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Int. J. Environ. Res. Public Health 2018, 15(10), 2226; https://doi.org/10.3390/ijerph15102226

Impacts of Type D Personality and Depression, Alone and in Combination, on Medication Non-Adherence Following Percutaneous Coronary Intervention

1
Red Cross College of Nursing, Chung-Ang University, Seoul 06974, Korea
2
College of Medicine, Division of Cardiology, Gachon University, Incheon 21565, Korea
3
Department of Community Health Sciences UCLA Fielding School of Public Health, Los Angeles, CA 90095-1771, USA
4
College of Nursing, Gachon University, Incheon 21936, Korea
*
Author to whom correspondence should be addressed.
Received: 13 September 2018 / Revised: 29 September 2018 / Accepted: 29 September 2018 / Published: 11 October 2018
(This article belongs to the Special Issue Dual Disorder Patients: Clinical and Therapeutical Aspects)
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Abstract

Background: Medication adherence after percutaneous coronary intervention (PCI) is essential to preventing the risk of restenosis. Even though Type D personality and depression have been known to affect medication non-adherence, their combined influence on PCI patients remains unclear. Aim: We aimed to identify how both Type D personality and depression were associated with medication non-adherence for 3 months after successful PCI. Methods: This prospective cohort study included 257 PCI patients, who took 3 or more cardiac medications, at a university hospital. We measured sociodemographic and clinical variables, Type D personality, depression, and medication non-adherence using face-to-face interviews and medical record reviews. Results: The total prevalence of medication non-adherence at the one- and three-month follow-ups was 14% and 16%, respectively. At one month, the prevalence of those with a combination of Type D personality and depression (23.4%) and depression alone (24%) was significantly higher than other groups. At three months, the prevalence of the Type D personality-only group (39.1%) was the highest. Type D personality increased the risk of medication non-adherence 5.089 times at three months, while depression increased it 2.6 times at one month. However, the risk of medication non-adherence was not increased in patients with combined Type D personality and depression. Conclusions: Individual assessments of Type D personality and depression are required. Therefore, psychological interventions focusing on personality and depression are crucial. Longitudinal follow-up studies must explore the interaction or individual impact of Type D personality and depression on medication non-adherence and other negative outcomes. View Full-Text
Keywords: Type D personality; depression; medication non-adherence; percutaneous coronary intervention Type D personality; depression; medication non-adherence; percutaneous coronary intervention
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Son, Y.-J.; Lee, K.; Morisky, D.E.; Kim, B.-H. Impacts of Type D Personality and Depression, Alone and in Combination, on Medication Non-Adherence Following Percutaneous Coronary Intervention. Int. J. Environ. Res. Public Health 2018, 15, 2226.

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