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Article

Clinical Profile and Aspects of Differential Diagnosis in Patients with ME/CFS from Latvia

1
Department of Infectology, Rīga Stradiņš University, 16 Dzirciema St., LV-1007 Riga, Latvia
2
Institute of Microbiology and Virology, Rīga Stradiņš University, 5 Ratsupites St., LV-1067 Riga, Latvia
3
Department of Family Medicine, Rīga Stradiņš University, 16 Dzirciema St., LV-1007 Riga, Latvia
*
Author to whom correspondence should be addressed.
Academic Editor: Tibor Hortobágyi
Medicina 2021, 57(9), 958; https://doi.org/10.3390/medicina57090958
Received: 16 July 2021 / Revised: 4 September 2021 / Accepted: 6 September 2021 / Published: 11 September 2021
(This article belongs to the Special Issue ME/CFS: Causes, Clinical Features and Diagnosis)
Background and objectives: There is still an uncertainty regarding the clinical symptomatology and the diagnostic criteria in terms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), as different diagnostic criteria exist. Our aim is to identify the core symptoms of ME/CFS in the outpatient setting in Riga; to distinguish symptoms in patients with ME/CFS and those with symptoms of fatigue; and to investigate patient thoughts on the onset, symptoms, treatment and effect of ME/CFS. Materials and methods: Total of 65 Caucasian patients from an ambulatory care setting were included in the study. Questionnaires, specialist evaluation of the patients and visual analogue scale (VAS) measurements were used to objectify the findings. Results: The study showed that ME/CFS with comorbidities is associated with a more severe disease. A negative correlation was found regarding an increase in age and number of current symptoms, as well as an increase in VAS score and the duration of fatigue and age in the ME/CFS without comorbidities group. Conclusions: Comorbidities tend to present with a more severe course of ME/CFS. Fatigue, myalgia, arthralgia and sleep disturbances tend to be more prevalent in the ME/CFS patients compared to the non-ME/CFS patients. VAS score has a tendency to decrease with age and duration of fatigue. Nonsteroidal anti-inflammatory drugs are the most commonly used pharmacological drug class that reduces ME/CFS symptoms. View Full-Text
Keywords: myalgic encephalomyelitis/chronic fatigue syndrome; symptoms; diagnosis; visual analogue scale myalgic encephalomyelitis/chronic fatigue syndrome; symptoms; diagnosis; visual analogue scale
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MDPI and ACS Style

Krumina, A.; Vecvagare, K.; Svirskis, S.; Gravelsina, S.; Nora-Krukle, Z.; Gintere, S.; Murovska, M. Clinical Profile and Aspects of Differential Diagnosis in Patients with ME/CFS from Latvia. Medicina 2021, 57, 958. https://doi.org/10.3390/medicina57090958

AMA Style

Krumina A, Vecvagare K, Svirskis S, Gravelsina S, Nora-Krukle Z, Gintere S, Murovska M. Clinical Profile and Aspects of Differential Diagnosis in Patients with ME/CFS from Latvia. Medicina. 2021; 57(9):958. https://doi.org/10.3390/medicina57090958

Chicago/Turabian Style

Krumina, Angelika, Katrine Vecvagare, Simons Svirskis, Sabine Gravelsina, Zaiga Nora-Krukle, Sandra Gintere, and Modra Murovska. 2021. "Clinical Profile and Aspects of Differential Diagnosis in Patients with ME/CFS from Latvia" Medicina 57, no. 9: 958. https://doi.org/10.3390/medicina57090958

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