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Volume 57
Issue 2
10.3390/medicina57020107
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Case Report

Atypical Cardiac Location of Melanoma of Unknown Origin

by
Agnieszka Styczeń
1,
Mariusz Kozak
1,
Marta Karaś-Głodek
1,
Elżbieta Czekajska-Chehab
2,
Andrzej Tomaszewski
1,
Andrzej Wysokiński
1 and
Tomasz Zapolski
1,*
1
Department of Cardiology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland
2
Department of Radiology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland
*
Author to whom correspondence should be addressed.
Medicina 2021, 57(2), 107; https://doi.org/10.3390/medicina57020107
Submission received: 12 December 2020 / Revised: 20 January 2021 / Accepted: 22 January 2021 / Published: 25 January 2021
(This article belongs to the Special Issue New Perspectives in the Treatment of Skin Disease)
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Abstract

The subject was a 66-year-old woman, suffering from the chest pain evoked by physical activity. Transthoracic echocardiography (TTE) revealed an abnormal structure, 41 × 29 mm. In MSCT, a hypodensic mobile tissue lesion that was infiltrating the whole thickness of left ventricle was confirmed. PET excluded the existence of other remote lesions. After surgical tumor removal, histopathological differential diagnosis revealed melanoma, myoepithelial cancer, and MPNST “high–grade” sarcoma. A control TTE detected a tumor that was 14 × 10 mm. After immunohistochemical results, immunotherapy with pembrolizumab was used, which resulted in complete tumor resolution. Presently, surgical resection and neoadjuvant targeted immunochemotherapy remain the treatment of choice for clinical stage III/IV melanoma.
Keywords: 64-slice multidetector computed tomography; echocardiogram; melanoma malignum; pembrolizumab 64-slice multidetector computed tomography; echocardiogram; melanoma malignum; pembrolizumab

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MDPI and ACS Style

Styczeń, A.; Kozak, M.; Karaś-Głodek, M.; Czekajska-Chehab, E.; Tomaszewski, A.; Wysokiński, A.; Zapolski, T. Atypical Cardiac Location of Melanoma of Unknown Origin. Medicina 2021, 57, 107. https://doi.org/10.3390/medicina57020107

AMA Style

Styczeń A, Kozak M, Karaś-Głodek M, Czekajska-Chehab E, Tomaszewski A, Wysokiński A, Zapolski T. Atypical Cardiac Location of Melanoma of Unknown Origin. Medicina. 2021; 57(2):107. https://doi.org/10.3390/medicina57020107

Chicago/Turabian Style

Styczeń, Agnieszka, Mariusz Kozak, Marta Karaś-Głodek, Elżbieta Czekajska-Chehab, Andrzej Tomaszewski, Andrzej Wysokiński, and Tomasz Zapolski. 2021. "Atypical Cardiac Location of Melanoma of Unknown Origin" Medicina 57, no. 2: 107. https://doi.org/10.3390/medicina57020107

APA Style

Styczeń, A., Kozak, M., Karaś-Głodek, M., Czekajska-Chehab, E., Tomaszewski, A., Wysokiński, A., & Zapolski, T. (2021). Atypical Cardiac Location of Melanoma of Unknown Origin. Medicina, 57(2), 107. https://doi.org/10.3390/medicina57020107

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