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Medicina, Volume 50, Issue 4

2014 August - 9 articles

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Articles (9)

  • Article
  • Open Access
7 Citations
1,030 Views
7 Pages

Postmastectomy internal mammary nodal irradiation: A long-term outcome

  • Eduardas Aleknavičius,
  • Vydmantas Atkočius,
  • Irena Kuzmickienė and
  • Rita Steponavičienė

7 October 2014

Background and objective: The internal mammary lymph nodes (IMN) have been recognized as a potential site of regional breast cancer spread. The aim of this study was to evaluate the impact of internal mammary node radiotherapy (RT) to on clinical out...

  • Article
  • Open Access
58 Citations
1,142 Views
8 Pages

Accumulation and biological effects of cobalt ferrite nanoparticles in human pancreatic and ovarian cancer cells

  • Vita Pašukonienė,
  • Agata Mlynska,
  • Simona Steponkienė,
  • Vilius Poderys,
  • Marija Matulionytė,
  • Vitalijus Karabanovas,
  • Urtė Statkutė,
  • Rasa Purvinienė,
  • Jan Aleksander Kraśko and
  • Ričardas Rotomskis
  • + 3 authors

6 October 2014

Background and objective: Superparamagnetic iron oxide nanoparticles (SPIONs) emerge as a promising tool for early cancer diagnostics and targeted therapy. However, both toxicity and biological activity of SPIONs should be evaluated in detail. The ai...

  • Other
  • Open Access
13 Citations
968 Views
7 Pages

Guidelines for diagnostics and treatment of aromatase inhibitor-induced bone loss in women with breast cancer A consensus of Lithuanian medical oncologists, radiation oncologists, endocrinologists, and family medicine physicians

  • Elona Juozaitytė,
  • Eduardas Aleknavičius,
  • Rasa Jančiauskienė,
  • Alvydas Česas,
  • Teresė Pipirienė-Želvienė,
  • Sigita Liutkauskienė,
  • Aurelija Krasauskienė and
  • Lina Vencevičienė

1 October 2014

The aim of this article is to inform about cancer treatment-induced bone loss, to identify patients at risk and those that can benefit from bone targeted treatment as well as highlight the importance of the multidisciplinary approach in the bone heal...

  • Article
  • Open Access
7 Citations
1,126 Views
7 Pages

Nevomelanocytic atypia detection by in vivo reflectance confocal microscopy

  • Ingrida Vaišnorienė,
  • Ričardas Rotomskis,
  • Vytautas Kulvietis,
  • Rimantas Eidukevičius,
  • Violeta Žalgevičienė,
  • Aida Laurinavičienė,
  • Jonas Venius and
  • Janina Didžiapetrienė

1 October 2014

Background and objective: In vivo reflectance confocal microscopy (RCM) is a promising novel technology for non-invasive early diagnostics of cutaneous melanoma. However, the possibility to detect melanocytic atypia in nevi by means of in vivo RCM re...

  • Article
  • Open Access
8 Citations
1,088 Views
8 Pages

The significance of reduced glutathione and glutathione S-transferase during chemoradiotherapy of locally advanced cervical cancer

  • Lina Daukantienė,
  • Birutė Kazbarienė,
  • Konstantinas Povilas Valuckas,
  • Janina Didžiapetrienė,
  • Aurelija Krikštaponienė and
  • Eduardas Aleknavičius

1 October 2014

Background and objective: To determine changes in reduced glutathione (GSH) and glutathione S-transferase (GST) during neoadjuvant chemotherapy followed by concurrent chemoradiation for patients with stage IIB–IIIB cervical cancer, and to evaluate th...

  • Case Report
  • Open Access
24 Citations
1,087 Views
6 Pages

1 October 2014

Sacral insufficiency fractures can occur as a complication after pelvic radiotherapy. Despite several recent studies showing high incidence of sacral insufficiency fractures in elderly women after pelvic radiotherapy this condition still remains unde...

  • Article
  • Open Access
35 Citations
1,283 Views
5 Pages

Significance of blood serum catalase activity and malondialdehyde level for survival prognosis of ovarian cancer patients

  • Janina Didžiapetrienė,
  • Jaroslav Bublevič,
  • Giedrė Smailytė,
  • Birutė Kazbarienė and
  • Rimantas Stukas

30 September 2014

Background and objective: Several markers were found to be potential prognostic factors in ovarian cancer. Among markers resembling systemic changes in the host's organism are markers of the oxidative stress. In this study we attempted to analyze the...

  • Article
  • Open Access
24 Citations
1,061 Views
6 Pages

Impact of microsatellite instability on survival of endometrial cancer patients

  • Daiva Kanopienė,
  • Giedrė Smailytė,
  • Jolanta Vidugirienė and
  • Jeff Bacher

30 September 2014

Background and objective: Endometrial cancer (EC) is the most commonly diagnosed gynecologic malignancy among women worldwide and may be classified on the basis of different molecular, pathologic and genetic alterations, including microsatellite inst...

  • Case Report
  • Open Access
3 Citations
928 Views
4 Pages

29 September 2014

Cetuximab (CTX) is used for the concurrent treatment with radiotherapy (RT) in squamous cell carcinoma of head and neck (HNSCC). There are no reliable clinical predictive markers of effectiveness of CTX at yet. We describe the clinical case of patien...

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Medicina - ISSN 1648-9144