Next Article in Journal
Application of Omics and Bioinformatics Tools in Streptococcus Research
Previous Article in Journal
ComDE Two-Component Signal Transduction Systems in Oral Streptococci: Structure and Function
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
CIMB
Volume 32
Issue 1
10.21775/cimb.032.259
cimb-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Current Issues in Molecular Biology is published by MDPI from Volume 43 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Caister Press.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Regulation of Cell Division in Streptococci: Comparing with the Model Rods

by
Zhenting Xiang
1,
Zongbo Li
1,
Jumei Zeng
2,
Yuqing Li
1,* and
Jiyao Li
1,*
1
State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
2
Department of Infectious Diseases, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA
*
Authors to whom correspondence should be addressed.
Curr. Issues Mol. Biol. 2019, 32(1), 259-326; https://doi.org/10.21775/cimb.032.259
Submission received: 8 March 2019 / Revised: 11 April 2019 / Accepted: 14 May 2019 / Published: 5 June 2019
Versions Notes

Abstract

Streptococcus is a genus of oval-shaped bacteria that act as both commensals and pathogens. Streptococcal infections are relevant to high morbidity and huge socioeconomic costs, with drug resistant strains becoming an increasing threat. Cell division plays an essential role during streptococcal colonization and infection, rendering it an ideal target for antibiotics. Substantial progress has been made to uncover the molecular biology and cellular processes of cell division, favoring the target strategies. This review discusses recent advances in our understanding of streptococcal cell division and its regulatory mechanisms regarding the conserved proteins, by comparing with model rods. Peptidoglycan synthesis that involved in septum formation and the maintenance of the unique oval shape have been spatiotemporally controlled in concert with the pace of division. With newly available tools of genetic and cytological study, streptococci will become an additional model bacterial system for cytokinesis and novel therapeutic agents that target cell division.
Keywords: regulation; division; streptococci; comparing; mmodel regulation; division; streptococci; comparing; mmodel

Share and Cite

MDPI and ACS Style

Xiang, Z.; Li, Z.; Zeng, J.; Li, Y.; Li, J. Regulation of Cell Division in Streptococci: Comparing with the Model Rods. Curr. Issues Mol. Biol. 2019, 32, 259-326. https://doi.org/10.21775/cimb.032.259

AMA Style

Xiang Z, Li Z, Zeng J, Li Y, Li J. Regulation of Cell Division in Streptococci: Comparing with the Model Rods. Current Issues in Molecular Biology. 2019; 32(1):259-326. https://doi.org/10.21775/cimb.032.259

Chicago/Turabian Style

Xiang, Zhenting, Zongbo Li, Jumei Zeng, Yuqing Li, and Jiyao Li. 2019. "Regulation of Cell Division in Streptococci: Comparing with the Model Rods" Current Issues in Molecular Biology 32, no. 1: 259-326. https://doi.org/10.21775/cimb.032.259

APA Style

Xiang, Z., Li, Z., Zeng, J., Li, Y., & Li, J. (2019). Regulation of Cell Division in Streptococci: Comparing with the Model Rods. Current Issues in Molecular Biology, 32(1), 259-326. https://doi.org/10.21775/cimb.032.259

Article Metrics

Back to TopTop