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Open AccessArticle

A Low-Cost Breath Analyzer Module in Domiciliary Non-Invasive Mechanical Ventilation for Remote COPD Patient Monitoring

1
Institute for Microelectronics and Microsystems, National Research Council (CNR-IMM), Campus Ecotekne, Str. Prov. Lecce-Monteroni km 1.2, 73100 Lecce, Italy
2
Institute of Clinical Physiology, National Research Council (CNR-IFC), Campus Ecotekne, Str. Prov. Lecce-Monteroni km 1.2, 73100 Lecce, Italy
3
“A. Perrino” Hospital, Pulmonology Ward, 72100 Brindisi, Italy
4
Institute for Research on Population and Social Policies, (CNR-IRPPS), 72100 Brindisi, Italy
*
Authors to whom correspondence should be addressed.
This paper is an expanded version of “Radogna, A.V.; Capone, S.; Di Lauro, G.A.; Fiore, N.; Francioso, L.; Casino, F.; Siciliano, P.; Sabina, S.; Sabato, E. A smart device for supporting mechanical ventilo-therapy” in Proceedings of the IEEE International Conference on IC Design and Technology (ICICDT 2018), Otranto, Italy, 4–6 June 2018.
Sensors 2020, 20(3), 653; https://doi.org/10.3390/s20030653
Received: 15 November 2019 / Revised: 14 January 2020 / Accepted: 17 January 2020 / Published: 24 January 2020
(This article belongs to the Special Issue Medical Applications of Sensor Systems and Devices)
Smart Breath Analyzers were developed as sensing terminals of a telemedicine architecture devoted to remote monitoring of patients suffering from Chronic Obstructive Pulmonary Disease (COPD) and home-assisted by non-invasive mechanical ventilation via respiratory face mask. The devices based on different sensors (CO2/O2 and Volatile Organic Compounds (VOCs), relative humidity and temperature (R.H. & T) sensors) monitor the breath air exhaled into the expiratory line of the bi-tube patient breathing circuit during a noninvasive ventilo-therapy session; the sensor raw signals are transmitted pseudonymized to National Health Service units by TCP/IP communication through a cloud remote platform. The work is a proof-of-concept of a sensors-based IoT system with the perspective to check continuously the effectiveness of therapy and/or any state of exacerbation of the disease requiring healthcare. Lab tests in controlled experimental conditions by a gas-mixing bench towards CO2/O2 concentrations and exhaled breath collected in a sampling bag were carried out to test the realized prototypes. The Smart Breath Analyzers were also tested in real conditions both on a healthy volunteer subject and a COPD suffering patient. View Full-Text
Keywords: COPD; exhaled breath; noninvasive ventilation; sensors; patient monitoring COPD; exhaled breath; noninvasive ventilation; sensors; patient monitoring
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Radogna, A.V.; Siciliano, P.A.; Sabina, S.; Sabato, E.; Capone, S. A Low-Cost Breath Analyzer Module in Domiciliary Non-Invasive Mechanical Ventilation for Remote COPD Patient Monitoring. Sensors 2020, 20, 653.

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