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Open AccessArticle

Performance Evaluation of Miniature Integrated Electrochemical Cells Fabricated Using LTCC Technology

Faculty of Microsystem Electronics and Photonics, Wrocław University of Technology, Z. Janiszewskiego 11/17, 50-372 Wrocław, Poland
Author to whom correspondence should be addressed.
This paper is an extended version of the conference paper: Influence of the Geometry on the LTCC Integrated Electrochemical Cells Performance. In Proceedings of the EUROSENSORS 2018, Graz, Austria, 9–12 September 2018.
Sensors 2019, 19(6), 1314;
Received: 31 January 2019 / Revised: 11 March 2019 / Accepted: 12 March 2019 / Published: 15 March 2019
(This article belongs to the Special Issue Eurosensors 2018 Selected Papers)
Miniaturized and integrated analytical devices, including chemical sensors, are at the forefront of modern analytical chemistry. The construction of novel analytical tools takes advantage of contemporary micro- and nanotechnologies, as well as materials science and technology. Two electrochemical techniques were used in experiments: electrochemical impedance spectroscopy and cyclic voltammetry. The goal of this study was to investigate electron transfer resistance in a model solution containing Fe 2 + / 3 + ions and protein adsorption using integrated electrochemical cells with different geometry. Tests performed at various Fe 2 + / 3 + concentration allowed to verify that these cells work properly. The influence of bovine serum albumin adsorbing to the surface of the integrated electrochemical cells was investigated. In electrochemical impedance spectroscopy, the value of R c t increased with protein adsorption and the relative change of R c t was in range 21% to 55%. In cyclic voltammetry the decreasing amperometric response of the working electrode was used as evidence of protein adsorption on the electrode. View Full-Text
Keywords: electrochemical impedance spectroscopy; cyclic voltammetry; protein adsorption; LTCC electrochemical impedance spectroscopy; cyclic voltammetry; protein adsorption; LTCC
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Szymanowska, P.; Nowak, D.; Piasecki, T. Performance Evaluation of Miniature Integrated Electrochemical Cells Fabricated Using LTCC Technology. Sensors 2019, 19, 1314.

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