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Open AccessArticle

Lab-on-Chip Cytometry Based on Magnetoresistive Sensors for Bacteria Detection in Milk

INESC–MN—Instituto de Engenharia de Sistemas e Computadores–Microsistemas e Nanotecnologias and IN—Institute of Nanoscience and Nanotechnology, Rua Alves Redol 9, 1000-029 Lisbon, Portugal
CIISA, Veterinary Medicine Faculty, Technical University of Lisbon, Av. da Universidade Técnica, 1300-477 Lisbon, Portugal
Physics Department, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal
INL, International Iberian Nanotechnology Laboratory, Av.Mestre Jose Veiga, 4715-330 Braga, Portugal
Authors to whom correspondence should be addressed.
Sensors 2014, 14(8), 15496-15524;
Received: 23 May 2014 / Revised: 14 July 2014 / Accepted: 1 August 2014 / Published: 21 August 2014
(This article belongs to the Special Issue Biomedical Sensors and Systems)
Flow cytometers have been optimized for use in portable platforms, where cell separation, identification and counting can be achieved in a compact and modular format. This feature can be combined with magnetic detection, where magnetoresistive sensors can be integrated within microfluidic channels to detect magnetically labelled cells. This work describes a platform for in-flow detection of magnetically labelled cells with a magneto-resistive based cell cytometer. In particular, we present an example for the validation of the platform as a magnetic counter that identifies and quantifies Streptococcus agalactiae in milk. View Full-Text
Keywords: cytometer; microfluidic; magnetoresistive sensor; milk; Streptococcus agalactiae cytometer; microfluidic; magnetoresistive sensor; milk; Streptococcus agalactiae
MDPI and ACS Style

Fernandes, A.C.; Duarte, C.M.; Cardoso, F.A.; Bexiga, R.; Cardoso, S.; Freitas, P.P. Lab-on-Chip Cytometry Based on Magnetoresistive Sensors for Bacteria Detection in Milk. Sensors 2014, 14, 15496-15524.

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