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Sensors 2014, 14(8), 15496-15524; https://doi.org/10.3390/s140815496

Lab-on-Chip Cytometry Based on Magnetoresistive Sensors for Bacteria Detection in Milk

1
INESC–MN—Instituto de Engenharia de Sistemas e Computadores–Microsistemas e Nanotecnologias and IN—Institute of Nanoscience and Nanotechnology, Rua Alves Redol 9, 1000-029 Lisbon, Portugal
2
CIISA, Veterinary Medicine Faculty, Technical University of Lisbon, Av. da Universidade Técnica, 1300-477 Lisbon, Portugal
3
Physics Department, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisbon, Portugal
4
INL, International Iberian Nanotechnology Laboratory, Av.Mestre Jose Veiga, 4715-330 Braga, Portugal
*
Authors to whom correspondence should be addressed.
Received: 23 May 2014 / Revised: 14 July 2014 / Accepted: 1 August 2014 / Published: 21 August 2014
(This article belongs to the Special Issue Biomedical Sensors and Systems)
Full-Text   |   PDF [4767 KB, uploaded 21 August 2014]

Abstract

Flow cytometers have been optimized for use in portable platforms, where cell separation, identification and counting can be achieved in a compact and modular format. This feature can be combined with magnetic detection, where magnetoresistive sensors can be integrated within microfluidic channels to detect magnetically labelled cells. This work describes a platform for in-flow detection of magnetically labelled cells with a magneto-resistive based cell cytometer. In particular, we present an example for the validation of the platform as a magnetic counter that identifies and quantifies Streptococcus agalactiae in milk. View Full-Text
Keywords: cytometer; microfluidic; magnetoresistive sensor; milk; Streptococcus agalactiae cytometer; microfluidic; magnetoresistive sensor; milk; Streptococcus agalactiae
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Fernandes, A.C.; Duarte, C.M.; Cardoso, F.A.; Bexiga, R.; Cardoso, S.; Freitas, P.P. Lab-on-Chip Cytometry Based on Magnetoresistive Sensors for Bacteria Detection in Milk. Sensors 2014, 14, 15496-15524.

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