Voltammetric Determination of Cocaine in Confiscated Samples Using a Carbon Paste Electrode Modified with Different [UO2(X-MeOsalen)(H2O)]·H2O Complexes
by
Laura Siqueira De Oliveira 1, Ana Paula Dos Santos Poles 1, Marco Antonio Balbino 1, Matheus Manoel Teles de Menezes 1, José Fernando De Andrade 1, Edward Ralph Dockal 2, Heloísa Maria Tristão 3 and Marcelo Firmino De Oliveira 1,*
Laura Siqueira De Oliveira 1, Ana Paula Dos Santos Poles 1, Marco Antonio Balbino 1, Matheus Manoel Teles de Menezes 1, José Fernando De Andrade 1, Edward Ralph Dockal 2, Heloísa Maria Tristão 3 and Marcelo Firmino De Oliveira 1,*
1
Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-901, São Paulo, Brasil
2
Centro de Ciências Exatas e de Tecnologia, Departamento de Química, Universidade Federal de São Carlos, São Carlos 13565-905, São Paulo, Brasil
3
Perícias Criminalísticas de Ribeirão Preto, Superintendência de Polícia Técnico-Científica do Estado de São Paulo, Ribeirão Preto14015-040, São Paulo, Brasil
*
Author to whom correspondence should be addressed.
Sensors 2013, 13(6), 7668-7679; https://doi.org/10.3390/s130607668
Received: 20 April 2013 / Revised: 27 May 2013 / Accepted: 5 June 2013 / Published: 14 June 2013
(This article belongs to the Special Issue Novel Tools in Electrochemical Sensing)
A fast and non-destructive voltammetric method to detect cocaine in confiscated samples based on carbon paste electrode modified with methoxy-substituted N,N'-ethylene-bis(salcylideneiminato)uranyl(VI)complexes, [UO2(X-MeOSalen)(H2O)]·H2O, where X corresponds to the positions 3, 4 or 5 of the methoxy group on the aromatic ring, is described. The electrochemical behavior of the modified electrode and the electrochemical detection of cocaine were investigated using cyclic voltammetry. Using 0.1 mol·L−1 KCl as supporting-electrolyte, a concentration-dependent, well-defined peak current for cocaine at 0.62 V, with an amperometric sensitivity of 6.25 × 104 μA·mol·L−1 for cocaine concentrations ranging between 1.0 × 10−7 and 1.3 × 10−6 mol·L−1 was obtained. Chemical interference studies using lidocaine and procaine were performed. The position of the methoxy group affects the results, with the 3-methoxy derivative being the most sensitive.
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Keywords:
forensic chemistry; cocaine; Schiff base complexes; chemically modified electrodes; cyclic voltammetry
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MDPI and ACS Style
De Oliveira, L.S.; Dos Santos Poles, A.P.; Balbino, M.A.; Teles de Menezes, M.M.; De Andrade, J.F.; Dockal, E.R.; Tristão, H.M.; De Oliveira, M.F. Voltammetric Determination of Cocaine in Confiscated Samples Using a Carbon Paste Electrode Modified with Different [UO2(X-MeOsalen)(H2O)]·H2O Complexes. Sensors 2013, 13, 7668-7679.
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