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Adaptive Optics Technology for High-Resolution Retinal Imaging
Fondazione G.B. Bietti IRCCS, Via Livenza 3, 00198 Rome, Italy
Applied Optics Group, School of Physics, National University of Ireland, Galway, Ireland
CNR-IPCF Unit of Support of Cosenza, c/o University of Calabria, Ponte P. Bucci Cubo 31/C,87036 Rende, Italy
Vision Engineering, Via Adda 7, 00198 Rome, Italy
* Author to whom correspondence should be addressed.
Received: 13 October 2012; in revised form: 5 December 2012 / Accepted: 6 December 2012 / Published: 27 December 2012
Abstract: Adaptive optics (AO) is a technology used to improve the performance of optical systems by reducing the effects of optical aberrations. The direct visualization of the photoreceptor cells, capillaries and nerve fiber bundles represents the major benefit of adding AO to retinal imaging. Adaptive optics is opening a new frontier for clinical research in ophthalmology, providing new information on the early pathological changes of the retinal microstructures in various retinal diseases. We have reviewed AO technology for retinal imaging, providing information on the core components of an AO retinal camera. The most commonly used wavefront sensing and correcting elements are discussed. Furthermore, we discuss current applications of AO imaging to a population of healthy adults and to the most frequent causes of blindness, including diabetic retinopathy, age-related macular degeneration and glaucoma. We conclude our work with a discussion on future clinical prospects for AO retinal imaging.
Keywords: adaptive optical systems; optical sensors; biomedical imaging techniques; eye
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MDPI and ACS Style
Lombardo, M.; Serrao, S.; Devaney, N.; Parravano, M.; Lombardo, G. Adaptive Optics Technology for High-Resolution Retinal Imaging. Sensors 2013, 13, 334-366.
Lombardo M, Serrao S, Devaney N, Parravano M, Lombardo G. Adaptive Optics Technology for High-Resolution Retinal Imaging. Sensors. 2013; 13(1):334-366.
Lombardo, Marco; Serrao, Sebastiano; Devaney, Nicholas; Parravano, Mariacristina; Lombardo, Giuseppe. 2013. "Adaptive Optics Technology for High-Resolution Retinal Imaging." Sensors 13, no. 1: 334-366.