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Exploring the Secrets of Long Noncoding RNAs

by 1,2, 1,2 and 1,2,*
1
National Engineering Laboratory for Tree Breeding, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China
2
Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China
*
Author to whom correspondence should be addressed.
Academic Editor: Martin Pichler
Int. J. Mol. Sci. 2015, 16(3), 5467-5496; https://doi.org/10.3390/ijms16035467
Received: 12 December 2014 / Revised: 22 February 2015 / Accepted: 3 March 2015 / Published: 10 March 2015
(This article belongs to the Collection Regulation by Non-Coding RNAs)
High-throughput sequencing has revealed that the majority of RNAs have no capacity to encode protein. Among these non-coding transcripts, recent work has focused on the roles of long noncoding RNAs (lncRNAs) of >200 nucleotides. Although many of their attributes, such as patterns of expression, remain largely unknown, lncRNAs have key functions in transcriptional, post-transcriptional, and epigenetic gene regulation; Also, new work indicates their functions in scaffolding ribonuclear protein complexes. In plants, genome-wide identification of lncRNAs has been conducted in several species, including Zea mays, and recent research showed that lncRNAs regulate flowering time in the photoperiod pathway, and function in nodulation. In this review, we discuss the basic mechanisms by which lncRNAs regulate key cellular processes, using the large body of knowledge on animal and yeast lncRNAs to illustrate the significance of emerging work on lncRNAs in plants. View Full-Text
Keywords: lncRNAs; functional genomics; transcriptional regulation; post-transcriptional regulation; epigenetics; lncRNAs in plants lncRNAs; functional genomics; transcriptional regulation; post-transcriptional regulation; epigenetics; lncRNAs in plants
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MDPI and ACS Style

Quan, M.; Chen, J.; Zhang, D. Exploring the Secrets of Long Noncoding RNAs. Int. J. Mol. Sci. 2015, 16, 5467-5496. https://doi.org/10.3390/ijms16035467

AMA Style

Quan M, Chen J, Zhang D. Exploring the Secrets of Long Noncoding RNAs. International Journal of Molecular Sciences. 2015; 16(3):5467-5496. https://doi.org/10.3390/ijms16035467

Chicago/Turabian Style

Quan, Mingyang; Chen, Jinhui; Zhang, Deqiang. 2015. "Exploring the Secrets of Long Noncoding RNAs" Int. J. Mol. Sci. 16, no. 3: 5467-5496. https://doi.org/10.3390/ijms16035467

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