Next Article in Journal
Silyl Ketene Acetals/B(C6F5)3 Lewis Pair-Catalyzed Living Group Transfer Polymerization of Renewable Cyclic Acrylic Monomers
Previous Article in Journal
Theoretical Calculation and Experimental Verification Demonstrated the Impossibility of Finding Haptens Identifying Triphenylmethane Dyes and Their Leuco Metabolites Simultaneously
Open AccessArticle

Moringa oleifera Leaf Extracts as Multifunctional Ingredients for “Natural and Organic” Sunscreens and Photoprotective Preparations

1
Department of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technology, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy
2
Universidad Estatal Amazónica (Km 2 ½ Via Napo (Paso Lateral)), Puyo, Pastaza EC160150, Ecuador
3
Ambrosialab Srl, Via Mortara 171, 44121 Ferrara, Italy
*
Author to whom correspondence should be addressed.
Molecules 2018, 23(3), 664; https://doi.org/10.3390/molecules23030664
Received: 26 February 2018 / Revised: 12 March 2018 / Accepted: 12 March 2018 / Published: 15 March 2018
(This article belongs to the Section Natural Products Chemistry)
Moringa oleifera has gained increasing popularity as a food supplement but not in the pharmaceutical and cosmetic area. The aim of this study was the preparation, characterization, and evaluation of extracts from the leaves of Moringa oleifera as a herbal sun care phytocomplex. Three different extracts of Moringa oleifera leaves, from Senegal, have been prepared and chemically characterized in the phenolic fraction by HPLC-DAD and Folin–Ciocalteu test. To explore photoprotective properties, an extensive evaluation of UV filtering, antioxidant (DPPH, FRAP, ORAC, PCL), and anti-hyperproliferative (human melanoma Colo38 cells) capacities have been conducted. Furthermore, a formulation study regarding cosmetic prototypes has been carried out in order to determine the Sun Protection Factor (SPF), which was assessed in vitro. The extracts were demonstrated to confer significant values of protection, with an SPF 2, that corresponds to a 50% protection against UV-B rays, at concentrations as low as 2% to 4%. Finally, the evaluation on potential irritation of the finished formulations was conducted by Patch Test and no significant irritant potential was observed. These evidence enlarged the already significant number of activities and potential uses of this plant, which is well-known for its importance in the medicinal and nutritional fields. View Full-Text
Keywords: Moringa oleifera; natural sunscreen; sustainable sources; SPF determination; dermo-cosmetic safety; anti-proliferative activity Moringa oleifera; natural sunscreen; sustainable sources; SPF determination; dermo-cosmetic safety; anti-proliferative activity
Show Figures

Graphical abstract

MDPI and ACS Style

Baldisserotto, A.; Buso, P.; Radice, M.; Dissette, V.; Lampronti, I.; Gambari, R.; Manfredini, S.; Vertuani, S. Moringa oleifera Leaf Extracts as Multifunctional Ingredients for “Natural and Organic” Sunscreens and Photoprotective Preparations. Molecules 2018, 23, 664.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop