Core-Shell Nanoencapsulation of α-Tocopherol by Blending Sodium Oleate and Rebaudioside A: Preparation, Characterization, and Antioxidant Activity
Abstract
:1. Introduction
2. Results and Discussion
2.1. Preparation and Characterization of α-TOC Loaded Nanoemulsions
2.2. Stability of α-TOC in the Freeze-Dried Samples
2.3. Interaction Forces Studied With FTIR
2.4. Particle Structures Studied with TEM
2.5. Release Profile of α-TOC from Nanoemulsion
2.6. Antioxidant Activity of Nanoemulsion
3. Materials and Methods
3.1. Materials
3.2. Preparation of Nanoemulsions
3.3. Characterization of Nanoemulsions
3.4. Encapsulation Efficiency of α-TOC
3.5. Freeze-Drying
3.6. Stability of α-TOC in the Freeze-Dried Sample
3.7. FTIR Spectra
3.8. Transmission Electron Microscopy (TEM)
3.9. Release Profile of α-TOC
3.10. Antioxidant Activity
3.11. Statistical Analysis
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Sample Availability: Samples of the compounds are not available from the authors. |
Model | Equation | Correlation Coefficient (r) |
---|---|---|
First order | ln(1 − Q) = −0.0049t − 0.1709 | 0.8323 |
Higuchi | Q = 0.0456t1/2 + 0.0527 | 0.9330 |
Hixcon Crowell | (1 − Q)1/3 = −0.0016t + 0.9499 | 0.8098 |
Nibergull | (1 − Q)1/2 = −0.0021t + 0.9183 | 0.8182 |
Weibull | lnln(1/(1 − Q)) = 0.536lnt − 2.7257 | 0.9629 |
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He, J.; Shi, H.; Huang, S.; Han, L.; Zhang, W.; Zhong, Q. Core-Shell Nanoencapsulation of α-Tocopherol by Blending Sodium Oleate and Rebaudioside A: Preparation, Characterization, and Antioxidant Activity. Molecules 2018, 23, 3183. https://doi.org/10.3390/molecules23123183
He J, Shi H, Huang S, Han L, Zhang W, Zhong Q. Core-Shell Nanoencapsulation of α-Tocopherol by Blending Sodium Oleate and Rebaudioside A: Preparation, Characterization, and Antioxidant Activity. Molecules. 2018; 23(12):3183. https://doi.org/10.3390/molecules23123183
Chicago/Turabian StyleHe, Junbo, Hao Shi, Shuangshuang Huang, Lijuan Han, Weinong Zhang, and Qixin Zhong. 2018. "Core-Shell Nanoencapsulation of α-Tocopherol by Blending Sodium Oleate and Rebaudioside A: Preparation, Characterization, and Antioxidant Activity" Molecules 23, no. 12: 3183. https://doi.org/10.3390/molecules23123183