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Open AccessArticle

Core-Shell Nanoencapsulation of α-Tocopherol by Blending Sodium Oleate and Rebaudioside A: Preparation, Characterization, and Antioxidant Activity

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Key Laboratory for Deep Processing of Major Grain and Oil, Ministry of Education, College of Food Science & Engineering, Wuhan Polytechnic University, Wuhan 430023, China
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Hubei Key Laboratory for Processing and Transformation of Agricultural Products, Wuhan Polytechnic University, Wuhan 430023, China
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Department of Food Science, The University of Tennessee, Knoxville, TN 37996, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Yangchao Luo
Molecules 2018, 23(12), 3183; https://doi.org/10.3390/molecules23123183
Received: 7 November 2018 / Revised: 28 November 2018 / Accepted: 1 December 2018 / Published: 3 December 2018
Nanoencapsulation of α-tocopherol (α-TOC) by blending sodium oleate (NaOl) and rebaudioside A (RebA) was successfully prepared by self-assembly method under mild conditions. The optimized nanoemulsion showed the loading capacity of α-TOC was 30 wt% of sodium oleate. FTIR analysis suggested that hydrogen bonds and hydrophobic interactions were the major forces in α-TOC-NaOl/RebA complexes that were spherical and possessed well-distinguishable core-shell structures. The freeze-dried α-TOC-NaOl/RebA complexes had great stability under ambient conditions. The release profile of α-TOC showed a first-order kinetics reaching around 67.9% after 90 h at 25 °C. Nanoencapsulation improved dispersibility and greatly increased the antioxidant activity of α-TOC. Therefore, the stable α-TOC-NaOl/RebA core-shell complexes prepared from “generally recognized as safe” (GRAS) ingredients have great potential to supplement α-TOC in food and cosmetic products. View Full-Text
Keywords: core-shell nanoencapsulation; α-tocopherol; sodium oleate; rebaudioside A; antioxidant activity core-shell nanoencapsulation; α-tocopherol; sodium oleate; rebaudioside A; antioxidant activity
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MDPI and ACS Style

He, J.; Shi, H.; Huang, S.; Han, L.; Zhang, W.; Zhong, Q. Core-Shell Nanoencapsulation of α-Tocopherol by Blending Sodium Oleate and Rebaudioside A: Preparation, Characterization, and Antioxidant Activity. Molecules 2018, 23, 3183.

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