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Open AccessArticle

Design of New-Generation Usable Forms of Topical Haemostatic Agents Containing Chitosan

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R&D Project Department, Institute of Security Technologies MORATEX, Lodz 90-505, Poland
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Team of Biomaterials, Institute of Biopolymers and Chemical Fibres, Lodz 90-570, Poland
*
Author to whom correspondence should be addressed.
Molecules 2017, 22(12), 2240; https://doi.org/10.3390/molecules22122240
Received: 2 November 2017 / Revised: 28 November 2017 / Accepted: 12 December 2017 / Published: 15 December 2017
Designing usable forms of topical haemostatic agents is the most important activity during the design process, resulting in strengthened functional properties of the final medical devices. This study aimed to propose indications for a research programme based on risk management supporting the development of two usable forms of a topical haemostatic agent: chitosan/alginate lyophilized foam and chitosan/alginate impregnated gauze. Both of the usable forms of the topical haemostatic agent, being the main part of the modified combat gauze, were fabricated using the chitosan/alginate complex. Risk analysis is helpful in developing an appropriate research programme, significantly reducing the risk to an acceptable level. View Full-Text
Keywords: chitosan; risk analysis; designing; haemostatic agents chitosan; risk analysis; designing; haemostatic agents
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Zielińska, D.; Struszczyk, M.H.; Madej-Kiełbik, L.; Chmal-Fudali, E.; Kucharska, M.; Wiśniewska-Wrona, M.; Brzoza-Malczewska, K. Design of New-Generation Usable Forms of Topical Haemostatic Agents Containing Chitosan. Molecules 2017, 22, 2240.

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