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Molecules 2017, 22(11), 2039;

Direct Modification of Microcrystalline Cellulose with Ethylenediamine for Use as Adsorbent for Removal Amitriptyline Drug from Environment

Federal Institute of Education, Science and Technology of Piauí, Teresina-Central Campus, IFPI, Teresina 64000-040, PI, Brazil
Federal Institute of Education, Science and Technology of Rio Grande do Norte, Nova Cruz Campus, IFRN, Nova Cruz 59215-000, RN, Brazil
Institute of Chemistry, State University of Campinas, UNICAMP, Barão Geraldo, Campinas 13083-970, SP, Brazil
Interdisciplinary Laboratory for Advanced Materials-LIMAV, UFPI, Teresina 64049-550, PI, Brazil
Laboratory of Polymers and Biomaterials (BioPolMat), UNIARA, Araraquara 14801-340, SP, Brazil
Author to whom correspondence should be addressed.
Received: 4 October 2017 / Revised: 2 November 2017 / Accepted: 17 November 2017 / Published: 22 November 2017
(This article belongs to the Special Issue Cellulose Chemical Modifications—Towards Sustainable Materials)
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Cellulose derivatives have been widely used as adsorbents for the removal of micropollutants such as drugs, dyes, and metals, due to their abundance, low cost and non-contaminating nature. In this context, several studies have been performed searching for new adsorbents (cellulose derivatives) efficient at contaminant removal from aqueous solutions. Thus, a new adsorbent was synthesized by chemical modification of cellulose with ethylenediamine in the absence of solvent and applied to the adsorption of amitriptyline (AMI) in aqueous solution. The modification reaction was confirmed by X-ray Diffraction (XRD), elemental analysis, Fourier Transform Infrared Spectroscopy (FTIR), Thermogravimetry/Differential Scanning Calorimeter (TG/DSC), solid state Nuclear Magnetic Resonance of 1H and 13C (1H-NMR and 13C-NMR). Moreover, the effectiveness of reaction was confirmed by computational calculations using Density Functional Theory (DFT) at level B3LYP/6-31G(d). This adsorption process was influenced by pH, time, concentration, temperature and did not show significant changes due to the ionic strength variation. Through these experiments, it was observed that the maximum adsorption capacity of AMI by CN polymer at 298 K, 300 min, and pH 7 was 87.66 ± 0.60 mg·g−1. View Full-Text
Keywords: modified cellulose; amitriptyline; adsorption modified cellulose; amitriptyline; adsorption

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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D. S. Bezerra, R.; C. Leal, R.; S. da Silva, M.; I. S. Morais, A.; H. C. Marques, T.; A. Osajima, J.; B. Meneguin, A.; Da S. Barud, H.; C. da Silva Filho, E. Direct Modification of Microcrystalline Cellulose with Ethylenediamine for Use as Adsorbent for Removal Amitriptyline Drug from Environment. Molecules 2017, 22, 2039.

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