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Molecules 2016, 21(1), 8;

The Synthesis of the Metabolites of 2′,3′,5′-Tri-O-acetyl-N6-(3-hydroxyphenyl) Adenosine (WS070117)

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China
Author to whom correspondence should be addressed.
Academic Editor: Maria Emília de Sousa
Received: 9 November 2015 / Revised: 15 December 2015 / Accepted: 16 December 2015 / Published: 28 December 2015
(This article belongs to the Section Metabolites)
Full-Text   |   PDF [880 KB, uploaded 28 December 2015]   |  


Seven metabolites of 2′,3′,5′-tri-O-acetyl-N6-(3-hydroxyphenyl) adenosine (WS070117) were synthesized by deacetylation, hydrolysis, cyclization, sulfonylation and glycosylation reactions, respectively. All these compounds, which could be useful as material standards for metabolic research, were characterized by NMR and HPLC-MS (ESI) analyses. View Full-Text
Keywords: WS070117; metabolites; synthesis WS070117; metabolites; synthesis

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Zhang, W.-X.; Wu, H.-N.; Li, B.; Wu, H.-L.; Wang, D.-M.; Wu, S. The Synthesis of the Metabolites of 2′,3′,5′-Tri-O-acetyl-N6-(3-hydroxyphenyl) Adenosine (WS070117). Molecules 2016, 21, 8.

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