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Open AccessArticle

An Efficient Synthesis of 1-Aryl-3-(indole-3-yl)-3-(2-aryl-1,2,3-triazol-4-yl)propan-1-one Catalyzed by a Brønsted Acid Ionic Liquid

by Chen-Jiang Liu 1,2,* and Chuan-Ji Yu 2
1
Physics and Chemistry Detecting Center, Xinjiang University, 830046 Urumqi, China
2
Key Laboratory of Oil and Gas Fine Chemicals Ministry of Education, School of Chemistry and Chemical Engineering, Xinjiang University, 830046 Urumqi, China
*
Author to whom correspondence should be addressed.
Molecules 2010, 15(12), 9197-9204; https://doi.org/10.3390/molecules15129197
Received: 11 October 2010 / Revised: 3 December 2010 / Accepted: 7 December 2010 / Published: 10 December 2010
An efficient synthesis of novel 1-aryl-3-(indole-3-yl)-3-(2-aryl-1,2,3-triazol-4-yl)propan-1-ones from indoles and 1-aryl-3-(2-aryl-1,2,3-triazol-4-yl)propan-1-one using a Brønsted acid ionic liquid [Sbmim][HSO4] as catalyst is described. Satisfactory results with excellent yields and short reaction time were obtained in the experiments. The catalyst could be recovered conveniently and reused efficiently. View Full-Text
Keywords: Brønsted acidic ionic liquid; Michael reaction; indoles; 1,2,3-triazole Brønsted acidic ionic liquid; Michael reaction; indoles; 1,2,3-triazole
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Liu, C.-J.; Yu, C.-J. An Efficient Synthesis of 1-Aryl-3-(indole-3-yl)-3-(2-aryl-1,2,3-triazol-4-yl)propan-1-one Catalyzed by a Brønsted Acid Ionic Liquid. Molecules 2010, 15, 9197-9204.

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