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Variation of Ursolic Acid Content in Eight Ocimum Species from Northeastern Brazil

Departamento de Química Analítica e Fisico-Química - Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, 60.455-970, Fortaleza, CE, Brazil
Laboratório de Química de Produtos Naturais, Universidade Estadual do Ceará, Campus do Itaperí, CEP 60.740-000, Fortaleza, CE, Brazil
Parque de Desenvolvimento Tecnológico (PADETEC), 60455-970, Fortaleza, CE, Brazil
Universidade de Fortaleza, 60811-905, Fortaleza, CE, Brazil
Author to whom correspondence should be addressed.
Molecules 2008, 13(10), 2482-2487;
Received: 27 June 2008 / Revised: 16 September 2008 / Accepted: 16 September 2008 / Published: 14 October 2008
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Ursolic acid is a very important compound due to its biological potential as an anti-inflammatory, trypanocidal, antirheumatic, antiviral, antioxidant and antitumoral agent. This study presents the HPLC analysis of ursolic acid (UA) content in eight different Ocimum species: O. americanum L., O. basilicum L, O. basilicum var purpurascens Benth, O. basilicum var. minimum L, O. gratissimum L, O. micranthum Willd, O. selloi Benth. and O. tenuiflorum L. grown in Northeastern Brazil. In these Ocimum species, UA was detected in different yields, with O. tenuiflorum showing the highest content (2.02%). This yield is very significant when compared with other sources of UA. View Full-Text
Keywords: Labiatae; Ursolic acid; Ocimum; HPLC Labiatae; Ursolic acid; Ocimum; HPLC

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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Silva, M.G.V.; Vieira, I.G.P.; Mendes, F.N.P.; Albuquerque, I.L.; Dos Santos, R.N.; Silva, F.O.; Morais, S.M. Variation of Ursolic Acid Content in Eight Ocimum Species from Northeastern Brazil. Molecules 2008, 13, 2482-2487.

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