Topic Editors
2. Animal and Veterinary Research Centre (CECAV), Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal
3. Center for the Study of Animal Sciences of the Institute of Sciences, Technologies and Agro-Environment of the University of Porto, CECA-ICETA, University of Porto, 4200-465 Porto, Portugal
Application of Animal Models: From Physiology to Pathology, 2nd Edition
Topic Information
Dear Colleagues,
We would like to invite submissions on the subject of animal models to this Topic, which is a continuation of a previously successful Topic.
The main objective of this Topic is to study the alterations in the different functions of the human body to elucidate the mechanisms underlying disease development. We particularly encourage hypothesis-driven studies that investigate the biological mechanisms linking normal physiological processes to pathological conditions.
In other words, we seek the keys to understand how imbalances in physiological processes lead to a series of pathological changes, such as alterations in organ or tissue function or the activation of certain cellular processes. Submissions should therefore aim to clarify the mechanistic relationships between physiological dysregulation and disease development and move beyond purely descriptive observations whenever possible.
The appearance of a disease may be subject to genetic or environmental factors or to a person’s lifestyle. Therefore, this Topic is responsible for analyzing all types of genetic mutations associated with complex conditions, as well as the reason why certain environmental factors may aggravate the disease.
In this way, new treatments can be developed to address these pathological processes or even to develop early detection programs to prevent the emergence of diseases such as diabetes.
In addition, this Topic can be of great use for the development of animal or cellular models in biomedical research. Studies using animal or cellular models should clearly justify model selection, address the biological question being investigated, and discuss the translational relevance and potential limitations of the model.
This Topic, titled ‘Application of Animal Models: From Physiology to Pathology, 2nd Edition’, covers the following fields:
- It helps us understand disease patterns: Pathophysiologist, physicians, and scientists can investigate and understand how diseases originate and how they can affect the human body. Studies addressing the underlying biological mechanisms of disease are particularly encouraged.
- It facilitates the development of specific treatments: This branch of study is very useful for creating new specific drugs that help reduce disease symptoms.
- It is useful for preventing the onset of diseases: Once the pathological mechanisms are understood, multiple conditions can be prevented, since the knowledge of their causes provide us with the information for preventing disease development.
- It allows the development of animal and cellular models to study diseases: Biomedical research also benefits those working in pathophysiology, and as a result, animal and cellular models can be developed for the study of diseases in laboratories. Manuscripts using experimental models should clearly describe their relevance for understanding human diseases and their potential translational implications.
- It helps to personalize medical care: As shown above, pathophysiology allows us to understand the causes that lead to the development of different conditions. In the case of a particular patient, physicians can plan specific treatments to treat their disease in a personalized way.
Dr. Juan Carlos Illera
Dr. Sara Cristina Caceres Ramos
Dr. Felisbina Luisa Queiroga
Topic Editors
Keywords
- physiology
- pathology
- disease
- treatment
- animal model
- biochemistry
- cellular processes
- therapy
Participating Journals
| Journal Name | Impact Factor | CiteScore | Launched Year | First Decision (median) | APC | |
|---|---|---|---|---|---|---|
Animals
|
3.2 | 5.5 | 2011 | 15.7 Days | CHF 2400 | Submit |
Cells
|
6.0 | 11.4 | 2012 | 14.9 Days | CHF 2700 | Submit |
Life
|
3.9 | 7.1 | 2011 | 15.3 Days | CHF 2600 | Submit |
Sci
|
4.1 | 5.4 | 2019 | 28.2 Days | CHF 1400 | Submit |
Veterinary Sciences
|
2.7 | 3.9 | 2014 | 16.3 Days | CHF 2100 | Submit |
Zoonotic Diseases
|
1.4 | 2.3 | 2021 | 27.5 Days | CHF 1200 | Submit |
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