Diabetes and Obesity Under Environmental Stressors: Mechanisms and Clinical Implications

Topic Information

Dear Colleagues,

Diabetes and obesity represent two of the most significant health challenges of the 21st century, with rising prevalence rates that continue to strain healthcare systems worldwide. Traditionally, research has focused on genetic predisposition, lifestyle factors, and metabolic dysregulation. However, growing evidence highlights the critical role of environmental stressors in shaping disease onset, progression, and clinical outcomes.

This Special Issue aims to advance our understanding of how external environmental factors interact with biological systems to influence metabolic health. Environmental stressors, including viruses, air pollution and climate-related exposures, endocrine-disrupting chemicals, chronic psychosocial stress, and urbanization, are increasingly recognized as key contributors to metabolic dysfunction, insulin resistance, and adipose tissue dysregulation. Particular attention is given to mechanistic pathways linking environmental exposures to metabolic disease, including oxidative stress, inflammation, mitochondrial dysfunction, epigenetic modifications, and alterations in the gut microbiome. These mechanisms provide a crucial bridge between environmental exposure and the clinical manifestations of metabolic disease, including diabetes and obesity.

We welcome original research and review articles exploring these themes and contributing to the advancement of this evolving field.

Dr. Ioanna Eleftheriadou
Dr. Dimitris Kounatidis
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Biomolecules biomolecules	4.8	9.3	2011	17.9 Days	CHF 2700	Submit
Diabetology diabetology	2.2	3.2	2020	24.4 Days	CHF 1400	Submit
International Journal of Molecular Sciences ijms	4.9	10.0	2000	17.8 Days	CHF 2900	Submit
Journal of Clinical Medicine jcm	2.9	5.2	2012	18.5 Days	CHF 2600	Submit
Metabolites metabolites	3.7	8.1	2011	16.7 Days	CHF 2700	Submit
Nutrients nutrients	5.0	10.2	2009	15 Days	CHF 2900	Submit

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