Advances in Analysis Methods for Metabolomics and Lipidomics
Topic Information
Dear Colleagues,
The increasing need for novel analytical approaches with higher selectivity, speed, and coverage is of the utmost importance in the fields of metabolomics and lipidomics. In terms of prognostics and diagnostics, the ability to quantify and identify different metabolites and lipids in biospecimes, such as biofluids, tissues and lysates, is crucial, while, the use of high-throughput techniques in clinical settings is also highly desirable. This Topic will be focused on the development, validation, and application of original methodologies based on hyphenated methods, such as UHPLC-MS, GC-MS, and CE-MS, aimed at the qualitative–quantitative analysis of metabolites and lipids in complex matrices such as cells, plasma, serum, urine, and tissue homogenates. Particular attention will be given to method optimization and validation as well as the identification and quantitation of the profiled metabolites and lipids.
Dr. Eduardo Sommella
Dr. Giulia Mazzoccanti
Dr. Emanuela Salviati
Topic Editors
Keywords
- hyphenated chromatography–mass spectrometry method
- metabolites
- lipids
- biological samples
- electrophoresis mass spectrometry
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