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22 Results Found

  • Review
  • Open Access
51 Citations
9,219 Views
14 Pages

Yessotoxin, a Promising Therapeutic Tool

  • Amparo Alfonso,
  • Mercedes R. Vieytes and
  • Luis M. Botana

28 January 2016

Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in se...

  • Review
  • Open Access
180 Citations
21,068 Views
30 Pages

Yessotoxins, a Group of Marine Polyether Toxins: an Overview

  • Beatriz Paz,
  • Antonio H. Daranas,
  • Manuel Norte,
  • Pilar Riobó,
  • José M. Franco and
  • José J. Fernández

7 May 2008

Yessotoxin (YTX) is a marine polyether toxin that was first isolated in 1986 from the scallop Patinopecten yessoensis. Subsequently, it was reported that YTX is produced by the dinoflagellates Protoceratium reticulatum, Lingulodinium polyedrum and Go...

  • Article
  • Open Access
15 Citations
3,899 Views
12 Pages

15 February 2022

The analysis of marine lipophilic toxins in shellfish products still represents a challenging task due to the complexity and diversity of the sample matrix. Liquid chromatography coupled with mass spectrometry (LC-MS) is the technique of choice for a...

  • Article
  • Open Access
16 Citations
13,675 Views
11 Pages

Is Yessotoxin the Main Phycotoxin in Croatian Waters?

  • Živana Ninčević Gladan,
  • Ivana Ujević,
  • Anna Milandri,
  • Ivona Marasović,
  • Alfiero Ceredi,
  • Silvia Pigozzi,
  • Jasna Arapov,
  • Sanda Skejić,
  • Stjepan Orhanović and
  • Igor Isajlović

5 March 2010

With the aim of investigating whether yessotoxin (YTX) is responsible for diarrhetic shellfish poisoning (DSP) events in Croatian waters, three different methods were combined: a modified mouse bioassay (MBA) that discriminates YTX from other DSP tox...

  • Review
  • Open Access
50 Citations
10,107 Views
20 Pages

16 March 2010

In this review, we focus on processes, organs and systems targeted by the marine toxins yessotoxin (YTX), okadaic acid (OA) and palytoxin (PTX). The effects of YTX and their basis are analyzed from data collected in the mollusc Mytilus galloprovincia...

  • Article
  • Open Access
29 Citations
6,382 Views
13 Pages

Combined Effects of Lipophilic Phycotoxins (Okadaic Acid, Azapsiracid-1 and Yessotoxin) on Human Intestinal Cells Models

  • Pierre-Jean Ferron,
  • Kevin Dumazeau,
  • Jean-François Beaulieu,
  • Ludovic Le Hégarat and
  • Valérie Fessard

19 February 2016

Phycotoxins are monitored in seafood because they can cause food poisonings in humans. Phycotoxins do not only occur singly but also as mixtures in shellfish. The aim of this study was to evaluate the in vitro toxic interactions of binary combination...

  • Article
  • Open Access
1 Citations
2,083 Views
16 Pages

16 November 2023

The presence of yessotoxins (YTXs) was analyzed in 10,757 samples of Galician bivalves from 2014 to 2022. Only YTX and 45-OH YTX were found. YTX was detected in 31% of the samples, while 45-OH YTX was found in 11.6% of them. Among the samples contain...

  • Article
  • Open Access
19 Citations
4,779 Views
13 Pages

Aerosolizable Marine Phycotoxins and Human Health Effects: In Vitro Support for the Biogenics Hypothesis

  • Emmanuel Van Acker,
  • Maarten De Rijcke,
  • Jana Asselman,
  • Ilse M. Beck,
  • Steve Huysman,
  • Lynn Vanhaecke,
  • Karel A.C. De Schamphelaere and
  • Colin R. Janssen

10 January 2020

Respiratory exposure to marine phycotoxins is of increasing concern. Inhalation of sea spray aerosols (SSAs), during harmful Karenia brevis and Ostreopsis ovata blooms induces respiratory distress among others. The biogenics hypothesis, however, sugg...

  • Article
  • Open Access
14 Citations
5,036 Views
24 Pages

23 July 2019

In vitro and in vivo studies have shown that phycotoxins can impact intestinal epithelial cells and can cross the intestinal barrier to some extent. Therefore, phycotoxins can reach cells underlying the epithelium, such as enteric glial cells (EGCs),...

  • Article
  • Open Access
35 Citations
9,241 Views
18 Pages

Acute Cardiotoxicity Evaluation of the Marine Biotoxins OA, DTX-1 and YTX

  • Sara F. Ferreiro,
  • Cristina Carrera,
  • Natalia Vilariño,
  • M. Carmen Louzao,
  • Germán Santamarina,
  • Antonio G. Cantalapiedra and
  • Luis M. Botana

27 March 2015

Phycotoxins are marine toxins produced by phytoplankton that can get accumulated in filter feeding shellfish. Human intoxication episodes occur due to contaminated seafood consumption. Okadaic acid (OA) and dynophysistoxins (DTXs) are phycotoxins res...

  • Commentary
  • Open Access
40 Citations
15,593 Views
12 Pages

23 July 2012

This work proposes to use the marine algal toxin yessotoxin (YTX) to establish reference model experiments to explore medically valuable effects from induction of multiple cell death pathways. YTX is one of few toxins reported to make such induction....

  • Article
  • Open Access
4 Citations
4,443 Views
27 Pages

Morphological, Phylogenetic and Toxinological Characterization of Potentially Harmful Algal Species from the Marine Coastal Waters of Buenos Aires Province (Argentina)

  • Jonás Adrián Tardivo Kubis,
  • Francisco Rodríguez,
  • Araceli E. Rossignoli,
  • Pilar Riobó,
  • Eugenia A. Sar and
  • Inés Sunesen

7 February 2023

In the framework of a monitoring program of harmful microalgae from the marine coastal waters of the Buenos Aires Province, seven strains were isolated and characterized by morphological and molecular analysis (LSU rDNA partial sequencing, D1–D...

  • Article
  • Open Access
17 Citations
4,400 Views
16 Pages

New Trends in the Occurrence of Yessotoxins in the Northwestern Adriatic Sea

  • Silva Rubini,
  • Sabrina Albonetti,
  • Simonetta Menotta,
  • Antonio Cervo,
  • Emanuele Callegari,
  • Monica Cangini,
  • Sonia Dall’Ara,
  • Erika Baldini,
  • Silvia Vertuani and
  • Stefano Manfredini

9 September 2021

Yessotoxins (YTXs) are polycyclic toxic ether compounds produced by phytoplanktonic dinoflagellates which accumulate in filter-feeding organisms. We know that the water temperature in our areas Northwestern Adriatic Sea is optimal for the growth of p...

  • Article
  • Open Access
13 Citations
3,452 Views
25 Pages

New Knowledge on Distribution and Abundance of Toxic Microalgal Species and Related Toxins in the Northwestern Black Sea

  • Nina Dzhembekova,
  • Snejana Moncheva,
  • Nataliya Slabakova,
  • Ivelina Zlateva,
  • Satoshi Nagai,
  • Stephan Wietkamp,
  • Marvin Wellkamp,
  • Urban Tillmann and
  • Bernd Krock

6 October 2022

Numerous potentially toxic plankton species commonly occur in the Black Sea, and phycotoxins have been reported. However, the taxonomy, phycotoxin profiles, and distribution of harmful microalgae in the basin are still understudied. An integrated mic...

  • Article
  • Open Access
27 Citations
7,885 Views
22 Pages

Occurrence of Lipophilic Marine Toxins in Shellfish from Galicia (NW of Spain) and Synergies among Them

  • Laura P. Rodríguez,
  • Virginia González,
  • Aníbal Martínez,
  • Beatriz Paz,
  • Jorge Lago,
  • Victoria Cordeiro,
  • Lucía Blanco,
  • Juan Manuel Vieites and
  • Ana G. Cabado

25 March 2015

Lipophilic marine toxins pose a serious threat for consumers and an enormous economic problem for shellfish producers. Synergistic interaction among toxins may play an important role in the toxicity of shellfish and consequently in human intoxication...

  • Review
  • Open Access
9 Citations
5,372 Views
17 Pages

Alzheimer’s Disease and Toxins Produced by Marine Dinoflagellates: An Issue to Explore

  • Maria João Botelho,
  • Jelena Milinovic,
  • Narcisa M. Bandarra and
  • Carlos Vale

2 April 2022

This paper examined the toxins naturally produced by marine dinoflagellates and their effects on increases in β-amyloid plaques along with tau protein hyperphosphorylation, both major drivers of Alzheimer’s disease (AD). This approach is i...

  • Article
  • Open Access
82 Citations
11,805 Views
12 Pages

Report on the First Detection of Pectenotoxin-2, Spirolide-A and Their Derivatives in French Shellfish

  • Zouher Amzil,
  • Manoella Sibat,
  • Florence Royer,
  • Nadine Masson and
  • Eric Abadie

23 November 2007

In the context of the French Phytoplankton and Phycotoxins MonitoringNetwork (REPHY) programme, shellfish samples were harvested from different locationswhere harmful algae blooms were known to have occurred. For all shellfish samples foundpositive b...

  • Article
  • Open Access
11 Citations
3,264 Views
19 Pages

Dissolved Algal Toxins along the Southern Coast of British Columbia Canada

  • Ryan B. Shartau,
  • Lenora D. M. Turcotte,
  • Julia C. Bradshaw,
  • Andrew R. S. Ross,
  • Blair D. Surridge,
  • Nina Nemcek and
  • Stewart C. Johnson

13 June 2023

Harmful algal blooms (HABs) in coastal British Columbia (BC), Canada, negatively impact the salmon aquaculture industry. One disease of interest to salmon aquaculture is Net Pen Liver Disease (NPLD), which induces severe liver damage and is believed...

  • Article
  • Open Access
18 Citations
6,427 Views
18 Pages

Occurrence and Seasonal Variations of Lipophilic Marine Toxins in Commercial Clam Species along the Coast of Jiangsu, China

  • Xin-Zhi Wang,
  • Ying Cheng,
  • Na Li,
  • Hong-Mei Wen,
  • Rui Liu,
  • Chen-Xiao Shan,
  • Chuan Chai and
  • Hao Wu

25 December 2015

Recent studies have examined lipophilic marine toxins (LMTs) in shellfish and toxic algae worldwide, but the occurrence and seasonal variations of LMTs in commercial clams (including Mactra veneriformis, Ruditapes philippinarum, Meretrix meretrix, an...

  • Article
  • Open Access
5 Citations
2,515 Views
16 Pages

3 November 2023

Algal toxins pose a serious threat to human and coastal ecosystem health, even if their potential impacts are poorly documented in New Caledonia (NC). In this survey, bivalves and seawater (concentrated through passive samplers) from bays surrounding...

  • Article
  • Open Access
2 Citations
1,962 Views
21 Pages

Effects of the Toxic Dinoflagellate Protoceratium reticulatum on Physiological Rates of Juvenile Scallops Argopecten purpuratus

  • María Gabriela Nieves,
  • Gonzalo Alvarez,
  • Jesús Antonio López-Carvallo,
  • Paulina Millanao,
  • Michael Araya,
  • Rosario Díaz and
  • Patricio A. Díaz

23 August 2024

Protoceratium reticulatum, a dinoflagellate species known for producing yessotoxins (YTX), can form harmful algal blooms (HABs) impacting marine life. This study examined how P. reticulatum influenced the physiological rates and affected the tissue h...

  • Article
  • Open Access
142 Citations
13,598 Views
21 Pages

Diarrhetic Shellfish Toxins and Other Lipophilic Toxins of Human Health Concern in Washington State

  • Vera L. Trainer,
  • Leslie Moore,
  • Brian D. Bill,
  • Nicolaus G. Adams,
  • Neil Harrington,
  • Jerry Borchert,
  • Denis A. M. Da Silva and
  • Bich-Thuy L. Eberhart

28 May 2013

The illness of three people in 2011 after their ingestion of mussels collected from Sequim Bay State Park, Washington State, USA, demonstrated the need to monitor diarrhetic shellfish toxins (DSTs) in Washington State for the protection of human heal...