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Open AccessReview

Yessotoxin, a Promising Therapeutic Tool

1
Department of Pharmacology, Faculty of Veterinary, University of Santiago of Compostela, 27002 Lugo, Spain
2
Department of Physiology, Faculty of Veterinary, University of Santiago of Compostela, 27002 Lugo, Spain
*
Authors to whom correspondence should be addressed.
Academic Editor: Peer B. Jacobson
Mar. Drugs 2016, 14(2), 30; https://doi.org/10.3390/md14020030
Received: 4 December 2015 / Revised: 15 January 2016 / Accepted: 18 January 2016 / Published: 28 January 2016
Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cells, cytoskeleton or activation of different cellular death types have been published as consequence of YTX exposure. This review summarizes the main intracellular pathways modulated by YTX and their pharmacological and therapeutic implications. View Full-Text
Keywords: yessotoxin (YTX); apoptosis; autophagy; cellular death; signal transduction; cytoskeleton; immune system; Alzheimer; glucose metabolism yessotoxin (YTX); apoptosis; autophagy; cellular death; signal transduction; cytoskeleton; immune system; Alzheimer; glucose metabolism
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MDPI and ACS Style

Alfonso, A.; Vieytes, M.R.; Botana, L.M. Yessotoxin, a Promising Therapeutic Tool. Mar. Drugs 2016, 14, 30.

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