Search Results (10,448)

This paper investigates co-continuous structures in immiscible polymer blends through three-dimensional (3D) computational calculations based on a multiphase phase-field equation for fluid flow. The mathematical model describes phase separation with the Cahn–Hilliard (CH) equation and fluid motion with the incompressible Navier–Stokes (NS) equations. Both polymers are treated as Newtonian viscous fluids, and the model includes surface tension, viscosity, and volume fraction effects. A semi-implicit finite difference method (FDM) solves the CH equation, and a projection method maintains the incompressibility of the flow field. Multigrid techniques solve the nonlinear systems efficiently. In addition, a connectivity-based detection algorithm determines whether a phase forms a connected structure that reaches all boundaries of the numerical domain. The numerical results show that the morphology changes from a droplet–matrix structure to a co-continuous structure as the volume fraction increases. The interfacial area per unit volume reaches a local maximum near the transition between these two regimes. Full article

This study aims to identify and synthesize the major global trends that shaped 2025 by applying the DeflyCompass methodology to a curated corpus of strategic foresight reports. The study synthesizes insights from 23 strategic reports published by leading international organizations, including the World Economic Forum, Accenture, Euromonitor, and major technology firms. Methodologically, DeflyCompass operationalizes a structured hybrid human–AI pipeline comprising the deployment of multi-agent AI systems, automated knowledge graph construction, semantic clustering, and hybrid human–AI validation processes, reducing an initial set of 816 preliminary signals to a validated catalog of 50 high-priority trends across six PESTEL domains: Political, Economic, Social, Technological, Environmental, and Legal/Governance. Key findings indicate that artificial intelligence functions as a systemic enabling technology across all domains, climate and sustainability imperatives permeate multiple domains, geopolitical fragmentation introduces systemic tension, and trust deficits emerge as a critical vulnerability. The study contributes a replicable and scalable framework for global-level strategic foresight that operationalizes human–AI integration within a rigorous expert-driven validation process, complementing existing hybrid analytical approaches in the literature. Implications extend to decision-making in technology governance, sustainability strategy, social adaptation, and scenario planning, highlighting the necessity of integrating AI augmentation with human expertise for effective future-oriented planning. Full article

Urban resilience plays a critical role in sustainable regional development. This is particularly so for ecologically vulnerable urban agglomerations undergoing rapid urbanization. This study examines the spatiotemporal development and driving mechanisms of urban resilience in the Chengdu–Chongqing Urban Agglomeration (CCUA) via the perspective of ecological risk. Using panel data from 16 prefecture-level cities during 2010–2023, this study constructs ecological risk and urban resilience indices were constructed based on the entropy weight–TOPSIS method. The coupling coordination degree model was applied to analyze the interactive dynamics between the two subsystems, and a two-way fixed effects panel model was employed to identify the impact of ecological risk on urban resilience and its moderating mechanisms. The results show that urban resilience experienced a foundational stabilization phase followed by gradual improvement, while ecological risk underwent a three-stage transformation characterized by accumulation, stabilization, and decline. The coupling degree between ecological risk and urban resilience remained moderately high, indicating structural tension within the regional system. Econometric analysis indicates that ecological risk significantly suppresses urban resilience. Infrastructure development has a positive direct effect on resilience. However, it negatively moderates the marginal impact of ecological risk, indicating a nonlinear and conditional risk–resilience relationship. Full article

Global environmental norms increasingly shape commodity governance in the Global South, with the EU Deforestation-Free Regulation (EUDR) representing a prominent attempt to govern land-based products through extraterritorial sustainability criteria. This study examines how such norms are received, reinterpreted, negotiated, and resisted in Indonesia’s palm oil sector, focusing on smallholder-dominated value chains in Serdang Bedagai and Simalungun, North Sumatra. Centered on everyday resistance and policy decoupling as its core interpretive lenses, and drawing on habitus as a supporting concept, the study employs qualitative fieldwork, in-depth interviews, field observations, and critical discourse analysis to investigate tensions between deforestation-free supply chain expectations and local realities marked by fragmented landholdings, informal tenure, intermediary dependence, and cashflow-oriented livelihood strategies. The findings show that the EUDR is widely perceived not as a sustainability opportunity, but as an externally imposed regulatory pressure that threatens income stability and market access. Local actors respond through discursive reframing, continued reliance on informal trading practices, and partial or symbolic implementation of legality and traceability requirements. The study argues that inclusive deforestation-free governance requires differentiated obligations, transitional legality pathways, and cooperative-based traceability mechanisms that better align global norms with local institutional capacity and livelihood structures. Full article

The SDGs and the New Urban Agenda both stress the importance of strengthening urban–rural linkages to promote balanced and inclusive development. Taking China as a case, this paper explores the underlying mechanisms driving the evolution of urban–rural relations. Existing studies have primarily periodized China’s urban–rural relations based on institutional changes, with limited attention to their endogenous evolutionary mechanisms. Drawing on New Institutional Economics, this study develops an “institutional–technological–cognitive” framework. It argues that China’s urban–rural relations have evolved through three stages: prior to the Reform and Opening-Up, institution-led governance resulted in urban–rural separation; in the 1980s–2010s, technological change reshaped the constraints and return structures of factor flows, resulting in urban–rural imbalance; in the 2010s–the present, early urban–rural integration was marked by tensions between cognitive reconstruction and existing institutional arrangements. Throughout the three stages, cognition has evolved from ideological cognition to opportunity-driven cognition and further to value-driven cognition, with its agency continuously strengthening and gradually becoming a key variable influencing the effectiveness of institutional operations and the pathways of technological empowerment. Accordingly, urban–rural relations should be understood not only as the outcome of factor allocation shaped by institutions and technology, but also as a dynamic structure embedded in the evolution of cognition. The advancement of urban–rural integration should place greater emphasis on people-centered cognitive transformation, rather than relying on improvements in factor mobility or population urbanization. Full article

Background: Handball involves unilateral, high-demand actions that increase injury risk. The Windlass mechanism (WM) is a position-dependent plantar fascia tensioning system, activated by dorsiflexion of the first metatarsophalangeal joint, which increases medial longitudinal arch stiffness and contributes to foot stability. WM activation can be mechanically simulated using hallux wedges to induce controlled dorsiflexion, allowing graded engagement of the mechanism under standardized conditions. The primary aim of this study was to investigate how different wedge inclinations, with and without visual biofeedback, affect foot muscle activity during squats in elite female handball players. Methods: Seventeen elite female handball players performed squats at 65% of one-repetition maximum under six conditions combining three wedge inclinations (0°, 10°, 30°) with the presence or absence of visual biofeedback. Electromyographic activity (RMS and %MVC) of intrinsic and extrinsic foot muscles was recorded. Results: A significant increase in left abductor hallucis activation with the 10° wedge without biofeedback. Visual biofeedback significantly increased RMS and %MVC in intrinsic foot muscles and increased RMS in the left gastrocnemius (p < 0.05). No significant interaction was observed between wedge inclination and biofeedback. Conclusions: Controlled activation of the WM via hallux wedges and the use of visual biofeedback modulate foot muscle activity during squats. These strategies may be considered in training programs aimed at improving foot stability and reducing injury risk in elite female handball players. Full article

A keloid is a benign fibroproliferative cutaneous disorder characterized by excessive extracellular matrix deposition, which is driven by persistent fibroblast proliferation and aberrant wound healing. Its complex pathogenesis involves genetic susceptibility, chronic inflammation, mechanical tension and dysregulated cellular signaling, resulting in poor clinical efficacy and high recurrence rates. Cellular senescence has recently become a central focus in exploring keloid pathophysiology, offering a novel perspective for elucidating its initiation, progression and recurrence. This review systematically summarizes the biological roles of cellular senescence in keloid pathology: it elaborates on the basic concepts and core molecular features of cellular senescence, details the spatial heterogeneity of senescent cell accumulation, the activation and pathological effects of senescence-associated secretory phenotype (SASP), and clarifies the molecular link between senescence-resumed proliferation (SRP) and keloid recurrence and treatment resistance. It also summarizes advances in senescence-related markers, the regulatory roles of the p53/p21 and Wnt/β-catenin pathways, and potential senescence-targeted therapies (senolytic, senomorphic, signaling intervention, cell reprogramming). Finally, we discuss the challenges and future perspectives for translating senescence research into clinical keloid treatments, aiming to provide a novel theoretical framework and therapeutic targets for keloid management. Full article

This qualitative study investigates the challenges teachers face when teaching English as a foreign language (EFL) to deaf (in this article, deaf (lower case) refers to the audiological condition of hearing loss, whereas Deaf (capitalized) is used to denote individuals who identify as members of the Deaf community and share a common sign language and distinct cultural values) and hard-of-hearing (DHH) students in German schools for the Deaf. The study is situated within a structural–theoretical professionalization framework, which focuses on the relationship between institutional conditions, teacher education structures, and professional action. Semi-structured interviews were conducted with 16 teachers of DHH students and the data were examined using qualitative content analysis. The findings reveal five central areas of challenge: (1) heterogeneity of the student body; (2) limited time (for preparing and adapting materials); (3) restricted subject-matter and sign-language competence, including missing links between EFL didactics and Deaf education in teacher training; (4) uncertainties surrounding the language design of EFL instruction, particularly the role of American Sign Language (ASL), German Sign Language (DGS), and written English; and (5) the lack of consistent, accessible exam formats and standards. Teachers report substantial insecurity due to the absence of coherent concepts, policy frameworks, and specialized training pathways, which fosters divergent classroom practices and tensions within teaching staff. The results highlight an urgent need for systematic integration of Deaf education, sign language training, and EFL pedagogy in teacher education, as well as for evidence-based guidelines on language classroom practice and assessment for DHH learners. Full article

This article examines the geopolitical transformation of the European Union within the context of polycrisis and intensified strategic rivalry following the events of 2022. It addresses the question of whether the EU’s response to contemporary crises represents a mere temporary adjustment triggered by an emergency, or rather a more permanent reconfiguration of European integration. Methodologically, the paper employs a qualitative research design combining conceptual analysis, interdisciplinary theoretical synthesis, and document-based comparative process-tracing of selected post-2022 policy responses, including sanctions policy, energy governance, and geoeconomic industrial policy. The analysis demonstrates that the EU has not evolved into a coherent, sovereign geopolitical actor, but rather into a more strategically adaptive and selectively integrated compound polity. This transformation is characterised by differentiated institutional deepening, expanded executive coordination, and growing tensions between efficiency, legitimacy, and democratic accountability. The article contributes to debates on European integration by conceptualising its current trajectory as a hybrid adaptation to a fragmented global order. Full article

From hours spent in waiting rooms amidst uncertainty to the experience of recovering from medical treatments, the lived time of illness is marked by intervals of suspended sense. By disorienting our relation to the future, illness disrupts and reconfigures lived time from within, shaping how we navigate our intersubjective milieu and make sense of our unfolding lives. In this paper, we introduce the phenomenological concept of “protentional friction” as a way of understanding these experiences. Drawing upon Simone de Beauvoir’s work on subjectivity and becoming, alongside Henri Bergson’s and Eugène Minkowski’s emphasis on durée and élan, we demonstrate how protentional friction allows us to negotiate the tensions of our situation, orient ourselves toward the future through projects, and gear into the ongoing work of sense-making. As a counterbalance to normalizing cultural discourses surrounding illness, we reinterpret the idea of the “quotidian” as the everyday practice of sense-making to find and sustain an equilibrium. Full article

In goafs formed by underground mineral resource extraction, the remaining pillars are often subjected to uniaxial loading at different loading rates, and their mechanical responses and failure mechanisms directly affect the long-term stability of the goafs. This study uses rock-like materials to conduct uniaxial compression tests at loading rates ranging from 0.001 mm/min to 0.05 mm/min, combined with acoustic emission (AE) monitoring, to systematically investigate the effects of loading rate on the mechanical properties, energy distribution, constitutive model, and AE characteristics of the material. The results show that an increase in loading rate significantly enhances the stiffness and strength of the material, promotes a transition in failure mode from a shear–tension composite to tension-dominated, intensifies brittle characteristics, and simultaneously inhibits full crack development and fragments generation. In terms of energy evolution, an increased loading rate enhances the pre-peak total strain energy and elastic strain energy storage but reduces the efficiency of energy dissipation, leading to an intensified mismatch between energy storage and dissipation capacities at peak stress. A damage variable induced by loading rate was proposed, and a damage constitutive model considering the loading rate was established, with the theoretical curves showing good agreement with the experimental data. AE characteristic analysis further reveals that an increase in loading rate causes the crack type to transition from shear-dominated to tension-dominated, and the fluctuating increase in the b-value reflects a reduction in pre-peak fracture scale and a decrease in the degree of material fragmentation. The research findings are expected to deepen the understanding of the damage and failure mechanisms of rock materials under different loading rates, thereby laying a research foundation for the stability assessment of goaf pillars and disaster warning. Full article

This paper addresses the optimal management of photovoltaic (PV) systems and distribution static synchronous compensators (D-STATCOMs) in modern electrical distribution networks. A mixed-integer nonlinear programming (MINLP) model is formulated which co-optimizes device placement, sizing, and multi-period dispatch to minimize the total annualized system costs while satisfying AC power flow and operational constraints. To solve this challenging problem, a decomposition methodology is proposed, wherein the binary location decisions for the PVs and D-STATCOMs are treated as predefined inputs, upon the basis of site selections commonly reported in the literature. With the integer variables fixed, the problem is reduced to a continuous nonlinear programming (NLP) subproblem for optimal capacity sizing and operational scheduling, which is solved using the interior point optimizer (IPOPT) via the Julia/JuMP environment. The core contribution of this work lies in its comprehensive demonstration of the economic superiority of variable reactive power injection over conventional fixed compensation schemes. Through numerical validation on standard 33- and 69-bus test systems, it is shown that a variable D-STATCOM operation yields substantial and consistent economic gains. Compared to optimized fixed-injection solutions, variable injection provides additional annual savings averaging USD 120,516 (33-bus feeder) and USD 125,620 (69-bus grid), corresponding to a further 3.4% reduction in total costs. These benefits prove robust across different device location sets identified by various metaheuristic algorithms, and they scale effectively to larger network topologies. The results demonstrate that transitioning to variable power injection is not merely an incremental improvement but a fundamental advancement for achieving techno-economic optimality in distribution system planning. The proposed methodology provides utilities with a computationally efficient framework for determining near-optimal PV and D-STATCOM management strategies by first fixing deployment locations based on established planning insights and then rigorously optimizing sizing and dispatch, in order to maximize economic returns while ensuring reliable network operation. Full article

Peru’s recent national mental health (MH) reforms aim to decentralise care and expand access to MH services for rural populations by integrating services into primary healthcare through the expansion of Community Mental Health Centres (CMHCs). Evidence on the implementation of these reforms at the local level remains limited. This qualitative study aimed to (i) describe the structure and implementation framework of MH services, (ii) analyse local understandings of MH; and (iii) examine pathways to care and identify barriers and facilitators to MH service implementation from both the supply (service providers) and demand (users and community members) perspectives. MH services were mapped across three provinces of northern Peru using a review of national MH policies, 2 focus group discussions, and 31 semi-structured interviews. Data were analysed thematically to explore local understandings of MH, pathways to care, and health system barriers. Local understandings of MH are shaped by cultural beliefs, social norms, and economic conditions, with many individuals experiencing distress initially relying on family networks or traditional healers. Stigma and expectations of a quick recovery hinder engagement with formal services. While the expansion of CMHCs has improved geographical access to specialised care in rural areas through proximity and being patient-centred, the implementation of respectful provider interactions remains uneven. Weak referral pathways and limited coordination between primary care centres and CMHCs frequently shift the responsibility for navigating care onto users and their families. Family involvement and culturally sensitive practices foster trust and support continued engagement. Persistent challenges include the limited capacity of service providers, high staff turnover, and the follow-up mechanisms, stigma, and tensions between cultural and biomedical understandings of MH. Peru’s expansion of CMHCs represents a significant health system reform to improve equitable access for rural populations. To sustain these gains, it will be necessary to strengthen workforce stability, clarify referral processes, and integrate culturally responsive approaches within primary care systems, offering lessons for similar resource-constrained contexts. Full article

C3H-type zinc finger proteins play essential roles in plant responses to abiotic stresses, as well as in the regulation of growth, development, and signal transduction. Birch (Betula platyphylla Suk.), an ecologically adaptable tree species widely distributed in northern regions, has not yet been systematically characterized for its C3H gene family. In this study, a total of 15 BpC3Hs were identified from a genome-wide analysis of birch. Their physiochemical properties, gene structures, conserved motifs and domains were systematically analyzed. Promoter analysis identified cis-acting elements associated with stress responses, hormone signaling, and developmental regulation. Transcriptome data further showed that most BpC3Hs were responsive to salt, drought, high/low-temperature stresses, and light/dark treatment, and showed differential expression patterns in tension wood and opposite wood. Additionally, they displayed stage-specific expression patterns during male inflorescence development. This study lays a foundation for future functional characterization of the C3H gene family in birch and its application in molecular breeding for stress resistance. Full article

While macroscopic stress significantly impacts the performance of metallic components, the underlying atom–electron coupling mechanisms governed by distinct crystal symmetries remain insufficiently understood. To address this gap, this work systematically investigates the structural and electronic evolution of representative metallic materials under applied stress. Experimentally, X-ray diffraction (XRD) revealed complex macroscopic residual stress distributions in cold rolled titanium alloy and silicon steel. Motivated by these engineering observations, first-principles density functional theory (DFT) calculations were conducted to uncover the underlying physical mechanisms. Specifically, the responses of face-centered cubic (FCC) aluminum and copper, body-centered cubic (BCC) iron, and hexagonal close-packed (HCP) titanium crystals were investigated under tension and compression using the RPBE functional. Stress-dependent elastic properties, density of states (DOS), band structures, and phonon spectra were calculated. Results show that tension softens all metals (Al becomes mechanically unstable), whereas compression stiffens their lattices. Electronically, tensile loading sharpens DOS peaks near the Fermi level and shifts conduction bands closer to it, whereas compression smooths DOS peaks and shifts bands away. Phonon analysis indicates Cu and Ti remain dynamically stable, while Al and Fe exhibit phonon mode softening under high tension. These stress-induced changes highlight crucial atom–electron coupling mechanisms, providing a theoretical basis for tailoring metallic performance via stress engineering. Full article