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Search Results (30,780)

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Keywords = sustainable processes

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22 pages, 4300 KiB  
Article
Optimised DNN-Based Agricultural Land Cover Mapping Using Sentinel-2 and Landsat-8 with Google Earth Engine
by Nisha Sharma, Sartajvir Singh and Kawaljit Kaur
Land 2025, 14(8), 1578; https://doi.org/10.3390/land14081578 (registering DOI) - 1 Aug 2025
Abstract
Agriculture is the backbone of Punjab’s economy, and with much of India’s population dependent on agriculture, the requirement for accurate and timely monitoring of land has become even more crucial. Blending remote sensing with state-of-the-art machine learning algorithms enables the detailed classification of [...] Read more.
Agriculture is the backbone of Punjab’s economy, and with much of India’s population dependent on agriculture, the requirement for accurate and timely monitoring of land has become even more crucial. Blending remote sensing with state-of-the-art machine learning algorithms enables the detailed classification of agricultural lands through thematic mapping, which is critical for crop monitoring, land management, and sustainable development. Here, a Hyper-tuned Deep Neural Network (Hy-DNN) model was created and used for land use and land cover (LULC) classification into four classes: agricultural land, vegetation, water bodies, and built-up areas. The technique made use of multispectral data from Sentinel-2 and Landsat-8, processed on the Google Earth Engine (GEE) platform. To measure classification performance, Hy-DNN was contrasted with traditional classifiers—Convolutional Neural Network (CNN), Random Forest (RF), Classification and Regression Tree (CART), Minimum Distance Classifier (MDC), and Naive Bayes (NB)—using performance metrics including producer’s and consumer’s accuracy, Kappa coefficient, and overall accuracy. Hy-DNN performed the best, with overall accuracy being 97.60% using Sentinel-2 and 91.10% using Landsat-8, outperforming all base models. These results further highlight the superiority of the optimised Hy-DNN in agricultural land mapping and its potential use in crop health monitoring, disease diagnosis, and strategic agricultural planning. Full article
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33 pages, 2015 KiB  
Article
From Development to Regeneration: Insights into Flight Muscle Adaptations from Bat Muscle Cell Lines
by Fengyan Deng, Valentina Peña, Pedro Morales-Sosa, Andrea Bernal-Rivera, Bowen Yang, Shengping Huang, Sonia Ghosh, Maria Katt, Luciana Andrea Castellano, Lucinda Maddera, Zulin Yu, Nicolas Rohner, Chongbei Zhao and Jasmin Camacho
Cells 2025, 14(15), 1190; https://doi.org/10.3390/cells14151190 (registering DOI) - 1 Aug 2025
Abstract
Skeletal muscle regeneration depends on muscle stem cells, which give rise to myoblasts that drive muscle growth, repair, and maintenance. In bats—the only mammals capable of powered flight—these processes must also sustain contractile performance under extreme mechanical and metabolic stress. However, the cellular [...] Read more.
Skeletal muscle regeneration depends on muscle stem cells, which give rise to myoblasts that drive muscle growth, repair, and maintenance. In bats—the only mammals capable of powered flight—these processes must also sustain contractile performance under extreme mechanical and metabolic stress. However, the cellular and molecular mechanisms underlying bat muscle physiology remain largely unknown. To enable mechanistic investigation of these traits, we established the first myoblast cell lines from the pectoralis muscle of Pteronotus mesoamericanus, a highly maneuverable aerial insectivore. Using both spontaneous immortalization and exogenous hTERT/CDK4 gene overexpression, we generated two stable cell lines that retain proliferative capacity and differentiate into contractile myotubes. These cells exhibit frequent spontaneous contractions, suggesting robust functional integrity at the neuromuscular junction. In parallel, we performed transcriptomic and metabolic profiling of native pectoralis tissue in the closely related Pteronotus parnellii to define molecular programs supporting muscle specialization. Gene expression analyses revealed enriched pathways for muscle metabolism, development, and regeneration, highlighting supporting roles in tissue maintenance and repair. Consistent with this profile, the flight muscle is triglyceride-rich, which serves as an important fuel source for energetically demanding processes, including muscle contraction and cellular recovery. Integration of transcriptomic and metabolic data identified three key metabolic modules—glucose utilization, lipid handling, and nutrient signaling—that likely coordinate ATP production and support metabolic flexibility. Together, these complementary tools and datasets provide the first in vitro platform for investigating bat muscle research, enabling direct exploration of muscle regeneration, metabolic resilience, and evolutionary physiology. Full article
37 pages, 2438 KiB  
Article
Application of Prodigiosin Extracts in Textile Dyeing and Novel Printing Processes for Halochromic and Antimicrobial Wound Dressings
by Cátia Alves, Pedro Soares-Castro, Rui D. V. Fernandes, Adriana Pereira, Rui Rodrigues, Ana Rita Fonseca, Nuno C. Santos and Andrea Zille
Biomolecules 2025, 15(8), 1113; https://doi.org/10.3390/biom15081113 (registering DOI) - 1 Aug 2025
Abstract
The textile industry’s reliance on synthetic dyes contributes significantly to pollution, highlighting the need for sustainable alternatives like biopigments. This study investigates the production and application of the biopigment prodigiosin, which was produced by Pseudomonas putida with a yield of 1.85 g/L. Prodigiosin [...] Read more.
The textile industry’s reliance on synthetic dyes contributes significantly to pollution, highlighting the need for sustainable alternatives like biopigments. This study investigates the production and application of the biopigment prodigiosin, which was produced by Pseudomonas putida with a yield of 1.85 g/L. Prodigiosin was prepared under acidic, neutral, and alkaline conditions, resulting in varying protonation states that influenced its affinity for cotton and polyester fibers. Three surfactants (anionic, cationic, non-ionic) were tested, with non-ionic Tween 80 yielding a promising color strength (above 4) and fastness results with neutral prodigiosin at 1.3 g/L. Cotton and polyester demonstrated good washing (color difference up to 14 for cotton, 5 for polyester) and light fastness (up to 15 for cotton, 16 for polyester). Cellulose acetate, used in the conventional printing process as a thickener, produced superior color properties compared to commercial thickeners. Neutral prodigiosin achieved higher color strength, and cotton fabrics displayed halochromic properties, distinguishing them from polyester, which showed excellent fastness. Prodigiosin-printed samples also exhibited strong antimicrobial activity against Pseudomonas aeruginosa and retained halochromic properties over 10 pH cycles. These findings suggest prodigiosin as a sustainable dye alternative and pH sensor, with potential applications in biomedical materials, such as antimicrobial and pH-responsive wound dressings. Full article
(This article belongs to the Special Issue Applications of Biomaterials in Medicine and Healthcare)
25 pages, 830 KiB  
Article
Writing Is Coding for Sustainable Futures: Reimagining Poetic Expression Through Human–AI Dialogues in Environmental Storytelling and Digital Cultural Heritage
by Hao-Chiang Koong Lin, Ruei-Shan Lu and Tao-Hua Wang
Sustainability 2025, 17(15), 7020; https://doi.org/10.3390/su17157020 (registering DOI) - 1 Aug 2025
Abstract
In the era of generative artificial intelligence, writing has evolved into a programmable practice capable of generating sustainable narratives and preserving cultural heritage through poetic prompts. This study proposes “Writing Is Coding ” as a paradigm for sustainability education, exploring how students engage [...] Read more.
In the era of generative artificial intelligence, writing has evolved into a programmable practice capable of generating sustainable narratives and preserving cultural heritage through poetic prompts. This study proposes “Writing Is Coding ” as a paradigm for sustainability education, exploring how students engage with AI-mediated multimodal creation to address environmental challenges. Using grounded theory methodology with 57 twelfth-grade students from technology-integrated high schools, we analyzed their experiences creating environmental stories and digital cultural artifacts using MidJourney, Kling, and Sora. Data collection involved classroom observations, semi-structured interviews, and reflective journals, analyzed through systematic coding procedures (κ = 0.82). Five central themes emerged: writing as algorithmic design for sustainability (89.5%), emotional scaffolding for environmental awareness (78.9%), aesthetics of imperfection in cultural preservation (71.9%), collaborative dynamics in sustainable creativity (84.2%), and pedagogical value of prompt literacy (91.2%). Findings indicate that AI deepens environmental consciousness and reframes writing as a computational process for addressing global issues. This research contributes a theoretical framework integrating expressive writing with algorithmic thinking in AI-assisted sustainability education, aligned with SDGs 4, 11, and 13. Full article
25 pages, 7708 KiB  
Review
A Review of Heat Transfer and Numerical Modeling for Scrap Melting in Steelmaking Converters
by Mohammed B. A. Hassan, Florian Charruault, Bapin Rout, Frank N. H. Schrama, Johannes A. M. Kuipers and Yongxiang Yang
Metals 2025, 15(8), 866; https://doi.org/10.3390/met15080866 (registering DOI) - 1 Aug 2025
Abstract
Steel is an important product in many engineering sectors; however, steelmaking remains one of the largest CO2 emitters. Therefore, new governmental policies drive the steelmaking industry toward a cleaner and more sustainable operation such as the gas-based direct reduction–electric arc furnace process. [...] Read more.
Steel is an important product in many engineering sectors; however, steelmaking remains one of the largest CO2 emitters. Therefore, new governmental policies drive the steelmaking industry toward a cleaner and more sustainable operation such as the gas-based direct reduction–electric arc furnace process. To become carbon neutral, utilizing more scrap is one of the feasible solutions to achieve this goal. Addressing knowledge gaps regarding scrap heterogeneity (size, shape, and composition) is essential to evaluate the effects of increased scrap ratios in basic oxygen furnace (BOF) operations. This review systematically examines heat and mass transfer correlations relevant to scrap melting in BOF steelmaking, with a focus on low Prandtl number fluids (thick thermal boundary layer) and dense particulate systems. Notably, a majority of these correlations are designed for fluids with high Prandtl numbers. Even for the ones tailored for low Prandtl, they lack the introduction of the porosity effect which alters the melting behavior in such high temperature systems. The review is divided into two parts. First, it surveys heat transfer correlations for single elements (rods, spheres, and prisms) under natural and forced convection, emphasizing their role in predicting melting rates and estimating maximum shell size. Second, it introduces three numerical modeling approaches, highlighting that the computational fluid dynamics–discrete element method (CFD–DEM) offers flexibility in modeling diverse scrap geometries and contact interactions while being computationally less demanding than particle-resolved direct numerical simulation (PR-DNS). Nevertheless, the review identifies a critical gap: no current CFD–DEM framework simultaneously captures shell formation (particle growth) and non-isotropic scrap melting (particle shrinkage), underscoring the need for improved multiphase models to enhance BOF operation. Full article
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20 pages, 804 KiB  
Article
Application of Animal- and Plant-Derived Coagulant in Artisanal Italian Caciotta Cheesemaking: Comparison of Sensory, Biochemical, and Rheological Parameters
by Giovanna Lomolino, Stefania Zannoni, Mara Vegro and Alberto De Iseppi
Dairy 2025, 6(4), 43; https://doi.org/10.3390/dairy6040043 (registering DOI) - 1 Aug 2025
Abstract
Consumer interest in vegetarian, ethical, and clean-label foods is reviving the use of plant-derived milk coagulants. Cardosins from Cynara cardunculus (“thistle”) are aspartic proteases with strong clotting activity, yet their technological impact in cheese remains under-explored. This study compared a commercial thistle extract [...] Read more.
Consumer interest in vegetarian, ethical, and clean-label foods is reviving the use of plant-derived milk coagulants. Cardosins from Cynara cardunculus (“thistle”) are aspartic proteases with strong clotting activity, yet their technological impact in cheese remains under-explored. This study compared a commercial thistle extract (PC) with traditional bovine rennet rich in chymosin (AC) during manufacture and 60-day ripening of Caciotta cheese. Classical compositional assays (ripening index, texture profile, color, solubility) were integrated with scanning electron microscopy, three-dimensional surface reconstruction, and descriptive sensory analysis. AC cheeses displayed slower but sustained proteolysis, yielding a higher and more linear ripening index, softer body, greater solubility, and brighter, more yellow appearance. Imaging revealed a continuous protein matrix with uniformly distributed, larger pores, consistent with a dairy-like sensory profile dominated by milky and umami notes. Conversely, PC cheeses underwent rapid early proteolysis that plateaued, producing firmer, chewier curds with lower solubility and darker color. Micrographs showed a fragmented matrix with smaller, heterogeneous pores; sensory evaluation highlighted vegetal, bitter, and astringent attributes. The data demonstrate that thistle coagulant can successfully replace animal rennet but generates cheeses with distinct structural and sensory fingerprints. The optimization of process parameters is therefore required when targeting specific product styles. Full article
(This article belongs to the Section Milk Processing)
26 pages, 1886 KiB  
Article
Landscape Ecological Risk Assessment of Peri-Urban Villages in the Yangtze River Delta Based on Ecosystem Service Values
by Yao Xiong, Yueling Li and Yunfeng Yang
Sustainability 2025, 17(15), 7014; https://doi.org/10.3390/su17157014 (registering DOI) - 1 Aug 2025
Abstract
The rapid urbanization process has accelerated the degradation of ecosystem services (ESs) in peri-urban rural areas of the Yangtze River Delta (YRD), leading to increasing landscape ecological risks (LERs). Establishing a scientifically grounded landscape ecological risk assessment (LERA) system and corresponding control strategies [...] Read more.
The rapid urbanization process has accelerated the degradation of ecosystem services (ESs) in peri-urban rural areas of the Yangtze River Delta (YRD), leading to increasing landscape ecological risks (LERs). Establishing a scientifically grounded landscape ecological risk assessment (LERA) system and corresponding control strategies is therefore imperative. Using rural areas of Jiangning District, Nanjing as a case study, this research proposes an optimized dual-dimensional coupling assessment framework that integrates ecosystem service value (ESV) and ecological risk probability. The spatiotemporal evolution of LER in 2000, 2010, and 2020 and its key driving factors were further studied by using spatial autocorrelation analysis and geodetector methods. The results show the following: (1) From 2000 to 2020, cultivated land remained dominant, but its proportion decreased by 10.87%, while construction land increased by 26.52%, with minimal changes in other land use types. (2) The total ESV increased by CNY 1.67 × 109, with regulating services accounting for over 82%, among which water bodies contributed the most. (3) LER showed an overall increasing trend, with medium- to highest-risk areas expanding by 55.37%, lowest-risk areas increasing by 10.10%, and lower-risk areas decreasing by 65.48%. (4) Key driving factors include landscape vulnerability, vegetation coverage, and ecological land connectivity, with the influence of distance to road becoming increasingly significant. This study reveals the spatiotemporal evolution characteristics of LER in typical peri-urban villages. Based on the LERA results, combined with terrain features and ecological pressure intensity, the study area was divided into three ecological management zones: ecological conservation, ecological restoration, and ecological enhancement. Corresponding zoning strategies were proposed to guide rural ecological governance and support regional sustainable development. Full article
20 pages, 10391 KiB  
Article
Sustainable Substitution of Petroleum-Based Processing Oils with Soybean-Derived Alternatives in Styrene–Butadiene Rubber: Effects on Processing Behavior and Mechanical Properties
by Yang-Wei Lin, Tsung-Yi Chen, Chen-Yu Chueh, Yi-Ting Chen, Tsunghsueh Wu and Hsi-Ming Hsieh
Polymers 2025, 17(15), 2129; https://doi.org/10.3390/polym17152129 (registering DOI) - 1 Aug 2025
Abstract
This study evaluates the replacement of petroleum-based naphthenic oil with four types of soybean-derived alternatives—virgin soybean oil (SBO), epoxidized SBO (ESBO), expired SBO, and recycled SBO—in styrene–butadiene rubber (SBR) composites. The materials were tested in both staining rubber (SR) and non-staining rubber (NSR) [...] Read more.
This study evaluates the replacement of petroleum-based naphthenic oil with four types of soybean-derived alternatives—virgin soybean oil (SBO), epoxidized SBO (ESBO), expired SBO, and recycled SBO—in styrene–butadiene rubber (SBR) composites. The materials were tested in both staining rubber (SR) and non-staining rubber (NSR) systems to assess processing characteristics, mechanical performance, and environmental durability. Among the alternatives, SBO demonstrated the best overall performance, improving processability and tensile strength by over 10%, while ESBO enhanced ozone resistance by 35% due to its epoxide functionality. Expired and recycled SBOs maintained essential mechanical properties within 90% of virgin SBO values. The full replacement of CH450 with SBO in tire prototypes resulted in burst strength exceeding 1000 kPa and stable appearance after 5000 km of road testing. To validate industrial relevance, the developed green tire was exhibited at the 2025 Taipei International Cycle Show, attracting interest from international buyers and stakeholders for its eco-friendly composition and carbon footprint reduction potential, thereby demonstrating both technical feasibility and commercial viability. Full article
(This article belongs to the Special Issue Functional Polymers and Their Composites for Sustainable Development)
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25 pages, 2805 KiB  
Review
Cascade Processing of Agricultural, Forest, and Marine Waste Biomass for Sustainable Production of Food, Feed, Biopolymers, and Bioenergy
by Swarnima Agnihotri, Ellinor B. Heggset, Juliana Aristéia de Lima, Ilona Sárvári Horváth and Mihaela Tanase-Opedal
Energies 2025, 18(15), 4093; https://doi.org/10.3390/en18154093 (registering DOI) - 1 Aug 2025
Abstract
An increasing global population, rising energy demands, and the shift toward a circular bioeconomy are driving the need for more resource-efficient waste management. The increase in the world population—now exceeding 8 billion as of 2024—results in an increased need for alternative proteins, both [...] Read more.
An increasing global population, rising energy demands, and the shift toward a circular bioeconomy are driving the need for more resource-efficient waste management. The increase in the world population—now exceeding 8 billion as of 2024—results in an increased need for alternative proteins, both human and feed grade proteins, as well as for biopolymers and bioenergy. As such, agricultural, forest, and marine waste biomass represent a valuable feedstock for production of food and feed ingredients, biopolymers, and bioenergy. However, the lack of integrated and efficient valorization strategies for these diverse biomass sources remains a major challenge. This literature review aims to give a systematic approach on the recent research status of agricultural, forest, and marine waste biomass valorization, focusing on cascade processing (a sequential combination of processes such as pretreatment, extraction, and conversion methods). Potential products will be identified that create the most economic value over multiple lifetimes, to maximize resource efficiency. It highlights the challenges associated with cascade processing of waste biomass and proposes technological synergies for waste biomass valorization. Moreover, this review will provide a comprehensive understanding of the potential of waste biomass valorization in the context of sustainable and circular bioeconomy. Full article
(This article belongs to the Special Issue Emerging Technologies for Waste Biomass to Green Energy and Materials)
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29 pages, 12910 KiB  
Article
Co-Creation, Co-Construction, and Co-Governance in Community Renewal: A Case Study of Civic Participation and Sustainable Mechanisms
by Yitong Shen, Ran Tan and Suhui Zhang
Land 2025, 14(8), 1577; https://doi.org/10.3390/land14081577 (registering DOI) - 1 Aug 2025
Abstract
This study focuses on Shanghai, a pioneer city in China’s community renewal practices. In recent years, community renewal driven by civic participation has become a prominent research topic, leading to the emergence of numerous exemplary cases in Shanghai. However, field investigations revealed that [...] Read more.
This study focuses on Shanghai, a pioneer city in China’s community renewal practices. In recent years, community renewal driven by civic participation has become a prominent research topic, leading to the emergence of numerous exemplary cases in Shanghai. However, field investigations revealed that many projects have experienced varying degrees of physical deterioration and a decline in spatial vitality due to insufficient maintenance, reflecting unsustainable outcomes. In response, this study examines a bottom-up community renewal project led by the research team, aiming to explore how broad civic participation can promote sustainable community renewal. A multidisciplinary approach incorporating perspectives from ecology, the humanities, economics, and sociology was used to guide citizen participation, while participatory observation methods recorded emotional shifts and maintenance behavior throughout the process. The results showed that civic participatory actions under the guidance of sustainability principles effectively enhanced citizens’ sense of community identity and responsibility, thereby facilitating the sustainable upkeep and operation of community spaces. However, the study also found that bottom-up efforts alone are insufficient. Sustainable community renewal also requires top-down policy support and institutional safeguards. At the end, the paper concludes by summarizing the practical outcomes and proposing strategies and mechanisms for broader application, aiming to provide a reference for related practices and research. Full article
(This article belongs to the Special Issue Planning for Sustainable Urban and Land Development, Second Edition)
20 pages, 3033 KiB  
Review
Recharge Sources and Flow Pathways of Karst Groundwater in the Yuquan Mountain Spring Catchment Area, Beijing: A Synthesis Based on Isotope, Tracers, and Geophysical Evidence
by Yuejia Sun, Liheng Wang, Qian Zhang and Yanhui Dong
Water 2025, 17(15), 2292; https://doi.org/10.3390/w17152292 (registering DOI) - 1 Aug 2025
Abstract
Karst groundwater systems are critical to water supply and ecological sustainability in northern China, yet their heterogeneity poses challenges for flow characterization. The Yuquan Mountain (YM) Spring, historically a major karst spring in western Beijing, has experienced persistent drying, raising concerns about its [...] Read more.
Karst groundwater systems are critical to water supply and ecological sustainability in northern China, yet their heterogeneity poses challenges for flow characterization. The Yuquan Mountain (YM) Spring, historically a major karst spring in western Beijing, has experienced persistent drying, raising concerns about its recharge and flow mechanisms. This study integrates published isotope data, spatial distributions of Na+ and Cl as hydrochemical tracers, groundwater age estimates, and geophysical survey results to assess the recharge sources and flow pathways within the YM Spring catchment area. The analysis identifies two major recharge zones: the Tanzhesi area, primarily recharged by direct infiltration of precipitation through exposed carbonate rocks, and the Junzhuang area, which receives mixed recharge from rainfall and Yongding River seepage. Three potential flow pathways are proposed, including shallow flow along faults and strata, and a deeper, speculative route through the Jiulongshan-Xiangyu syncline. The synthesis of multiple lines of evidence leads to a refined conceptual model that illustrates how geological structures govern recharge, flow, and discharge processes in this karst system. These findings not only enhance the understanding of subsurface hydrodynamics in complex geological settings but also provide a scientific basis for future spring restoration planning and groundwater management strategies in the regions. Full article
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18 pages, 3271 KiB  
Article
Mobile App–Induced Mental Fatigue Affects Strength Asymmetry and Neuromuscular Performance Across Upper and Lower Limbs
by Andreas Stafylidis, Walter Staiano, Athanasios Mandroukas, Yiannis Michailidis, Lluis Raimon Salazar Bonet, Marco Romagnoli and Thomas I. Metaxas
Sensors 2025, 25(15), 4758; https://doi.org/10.3390/s25154758 (registering DOI) - 1 Aug 2025
Abstract
This study aimed to investigate the effects of mental fatigue on physical and cognitive performance (lower-limb power, isometric and handgrip strength, and psychomotor vigilance). Twenty-two physically active young adults (12 males, 10 females; Mage = 20.82 ± 1.47) were randomly assigned to [...] Read more.
This study aimed to investigate the effects of mental fatigue on physical and cognitive performance (lower-limb power, isometric and handgrip strength, and psychomotor vigilance). Twenty-two physically active young adults (12 males, 10 females; Mage = 20.82 ± 1.47) were randomly assigned to either a Mental Fatigue (MF) or Control group (CON). The MF group showed a statistically significant (p = 0.019) reduction in non-dominant handgrip strength, declining by approximately 2.3 kg (about 5%), while no such change was observed in the CON group or in dominant handgrip strength across groups. Reaction time (RT) was significantly impaired following the mental fatigue protocol: RT increased by 117.82 ms, representing an approximate 46% longer response time in the MF group (p < 0.001), whereas the CON group showed a smaller, non-significant increase of 32.82 ms (~12% longer). No significant differences were found in squat jump performance, indicating that lower-limb explosive power may be less affected by acute mental fatigue. These findings demonstrate that mental fatigue selectively impairs fine motor strength and cognitive processing speed, particularly reaction time, while gross motor power remains resilient. Understanding these effects is critical for optimizing performance in contexts requiring fine motor control and sustained attention under cognitive load. Full article
(This article belongs to the Special Issue Sensing Human Cognitive Factors)
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18 pages, 5287 KiB  
Article
Heuristic Optimization Rules Applied for the Sustainable Design of Lightweight Engineering Structures Under Loads Subject to Random Changes
by Katarzyna Tajs-Zielińska and Bogdan Bochenek
Sustainability 2025, 17(15), 7011; https://doi.org/10.3390/su17157011 (registering DOI) - 1 Aug 2025
Abstract
In engineering design, optimization is crucial for achieving sustainable goals. This involves creating environmentally responsible structures. Optimizing the design is the first step in reducing the environmental impact of construction. Topology optimization (TO) is one way to do this. TO is the process [...] Read more.
In engineering design, optimization is crucial for achieving sustainable goals. This involves creating environmentally responsible structures. Optimizing the design is the first step in reducing the environmental impact of construction. Topology optimization (TO) is one way to do this. TO is the process of designing the material layout in the design domain according to selected criteria. The criteria can be explicitly defined to promote sustainability. As a result, a new structure topology is proposed to make the structure both lightweight and durable, with the aim of improving its functionality and reducing its environmental impact. In optimal engineering design, it is particularly important to take into account the structure’s special operating conditions, e.g., loads subject to random changes. Predicting topologies under such conditions is important since random load changes can significantly affect the resulting topologies. In this paper, an easy to implement numerical method for this kind of problem is proposed. The basic idea is to transform a random loads case into the deterministic problem of multiple loads. A heuristic method of Cellular Automata is proposed as a numerical optimization tool. The examples of topology optimization have been performed to illustrate the concept, confirming the efficiency, versatility, and ease of its implementation. Full article
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19 pages, 300 KiB  
Review
Sprouted Grains as a Source of Bioactive Compounds for Modulating Insulin Resistance
by Yan Sun, Caiyun Li and Aejin Lee
Appl. Sci. 2025, 15(15), 8574; https://doi.org/10.3390/app15158574 (registering DOI) - 1 Aug 2025
Abstract
Sprouted grains are gaining attention as a natural and sustainable source of bioactive compounds with potential benefits in managing insulin resistance (IR), a hallmark of obesity-related metabolic disorders. This review aims to synthesize current findings on the biochemical changes induced during grain germination [...] Read more.
Sprouted grains are gaining attention as a natural and sustainable source of bioactive compounds with potential benefits in managing insulin resistance (IR), a hallmark of obesity-related metabolic disorders. This review aims to synthesize current findings on the biochemical changes induced during grain germination and their relevance to metabolic health. We examined recent in vitro, animal, and human studies focusing on how germination enhances the nutritional and functional properties of grains, particularly through the synthesis of compounds such as γ-aminobutyric acid, polyphenols, flavonoids, and antioxidants, while reducing anti-nutritional factors. These bioactive compounds have been shown to modulate metabolic and inflammatory pathways by inhibiting carbohydrate-digesting enzymes, suppressing pro-inflammatory cytokines, improving redox balance, and influencing gut microbiota composition. Collectively, these effects contribute to improved insulin sensitivity and glycemic control. The findings suggest that sprouted grains serve not only as functional food ingredients but also as accessible dietary tools for preventing or alleviating IR. Their role in delivering multiple bioactive molecules through a simple, environmentally friendly process highlights their promise in developing future nutrition-based strategies for metabolic disease prevention. Full article
(This article belongs to the Special Issue New Insights into Bioactive Compounds)
33 pages, 949 KiB  
Article
Evaluating Freshwater, Desalinated Water, and Treated Brine as Water Feed for Hydrogen Production in Arid Regions
by Hamad Ahmed Al-Ali and Koji Tokimatsu
Energies 2025, 18(15), 4085; https://doi.org/10.3390/en18154085 (registering DOI) - 1 Aug 2025
Abstract
Hydrogen production is increasingly vital for global decarbonization but remains a water- and energy-intensive process, especially in arid regions. Despite growing attention to its climate benefits, limited research has addressed the environmental impacts of water sourcing. This study employs a life cycle assessment [...] Read more.
Hydrogen production is increasingly vital for global decarbonization but remains a water- and energy-intensive process, especially in arid regions. Despite growing attention to its climate benefits, limited research has addressed the environmental impacts of water sourcing. This study employs a life cycle assessment (LCA) approach to evaluate three water supply strategies for hydrogen production: (1) seawater desalination without brine treatment (BT), (2) desalination with partial BT, and (3) freshwater purification. Scenarios are modeled for the United Arab Emirates (UAE), Australia, and Spain, representing diverse electricity mixes and water stress conditions. Both electrolysis and steam methane reforming (SMR) are evaluated as hydrogen production methods. Results show that desalination scenarios contribute substantially to human health and ecosystem impacts due to high energy use and brine discharge. Although partial BT aims to reduce direct marine discharge impacts, its substantial energy demand can offset these benefits by increasing other environmental burdens, such as marine eutrophication, especially in regions reliant on carbon-intensive electricity grids. Freshwater scenarios offer lower environmental impact overall but raise water availability concerns. Across all regions, feedwater for SMR shows nearly 50% lower impacts than for electrolysis. This study focuses solely on the environmental impacts associated with water sourcing and treatment for hydrogen production, excluding the downstream impacts of the hydrogen generation process itself. This study highlights the trade-offs between water sourcing, brine treatment, and freshwater purification for hydrogen production, offering insights for optimizing sustainable hydrogen systems in water-stressed regions. Full article
(This article belongs to the Special Issue Advances in Hydrogen Production in Renewable Energy Systems)
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