Search Results (5,639)

Material selection in architectural design necessitates a multifaceted evaluation of economic, technical, esthetic, and cultural variables. Beyond fundamental requirements such as cost, structural integrity, and transparency, architects must synthesize subjective attributes, including warmth and formality, with objective constraints like multifunctionality and cultural heritage. Despite the strategic impact of material choice on project performance, empirical research systematically categorizing these governing criteria remains sparse. Furthermore, existing methodologies often overlook the psychophysical principles of human perception essential for construction material evaluation. Thus, this study identifies the fundamental factors influencing material selection and establishes a hierarchical framework to prioritize their relative significance within the design process. The research employs a weighted Analytic Hierarchy Process integrated with the Weber–Fechner law (W-AHP) to structure and quantify selection criteria. By incorporating perceptual scaling principles into the AHP framework, the methodology accounts for variations in judgment sensitivity across different evaluation scales. A hierarchical decision model was developed to categorize criteria and sub-criteria, followed by pairwise comparisons to derive priority weights. Results reveal a distinct priority hierarchy among the identified criteria and confirm that judgment sensitivity varies significantly across evaluation scales. The W-AHP method produced differentiated weightings that accurately reflect the psychological intensity of professional decision-making, offering a structured mechanism to balance functional performance with complex design intentions. This study contributes to the field of construction management by introducing the W-AHP method as a novel decision-support tool. The integration of Weber–Fechner perceptual principles enhances weight differentiation and addresses the inherent subjectivity of architectural evaluation, providing a transparent methodology to justify material procurement within a rigorous engineering management context. Full article

Aesthetic medicine is shifting from symptomatic correction to biological structural restoration. Regenerative aesthetics represents a frontier in dermatology, focusing on the restoration of the skin microenvironment to enhance cellular vitality and tissue resilience. Central to this approach is the concept of “skin bed preparation”, a strategic priming phase designed to optimize the physiological terrain before the delivery of advanced aesthetic interventions. This review explores the molecular and cellular mechanisms by which skin bed preparation modulates the extracellular matrix (ECM) and the dermal niche to maximize the efficacy of subsequent treatments and promote long-term skin longevity. Evidence suggests that biostimulatory priming utilizing senolytics, senomorphics, mitochondrial, and/or epigenetic rejuvenators rehabilitates the fibroblast–collagen interactome. By reducing oxidative stress and chronic low-grade inflammation, these preparatory steps transition the skin from a catabolic to an anabolic state. This metabolic reset ensures that subsequent procedures, such as laser therapy, injectable fillers, encounter a responsive cellular environment, resulting in superior collagen induction and prolonged clinical outcomes. Optimizing the skin microenvironment via regenerative aesthetics is not merely an adjunctive step but a fundamental requirement for therapeutic success. Integrating skin bed preparation into clinical protocols provides a synergistic framework that enhances immediate procedural results while addressing the underlying hallmarks of skin aging, ultimately redefining the trajectory of skin health and longevity. Full article

The expansion of accessible, fine-grained city data has significantly increased opportunities for evidence-based and informed policy-making. Despite this evolution, extracting actionable insights from heterogeneous data sources and effectively communicating findings remain persistent challenges. Most existing visualisation approaches and research prioritise technical implementation by focusing on how to visualise, often neglecting the importance of policy-driven visualisation questions and data contexts. This led to flawed analyses, particularly in complex domains such as smart cities and urban policy-making using digital twins. This article presents a novel, practical, step-by-step policy visualisation methodology grounded in empirical smart city research, shifting the emphasis toward policy-element-based questions informed by data-informed evidence. The methodology was successfully applied, tested, and adapted, resulting in an implementable, structured, and integrative approach that aligns with policymakers’ established policy design, implementation, and evaluation cycles. Through this approach, 20 user-driven smart city policy visualisations were operationalised and implemented in strategic policy decision-making contexts across smart city domains, including mobility, spatial planning, and environment. The results demonstrate how dashboards, algorithmic simulations, and digital twins visualisations can be systematically deployed to support evidence-informed decision-making. Full article

The transition towards sustainable urban mobility requires planning approaches that integrate accessibility, social inclusion, environmental quality, and stakeholder preferences, particularly in medium-sized cities, where mobility challenges differ from those of large metropolitan areas. However, comparative evidence on how different stakeholder groups prioritize sustainable mobility strategies in such cities remains limited. This paper addresses this gap by applying a comparative Multi-Actor Multi-Criteria Analysis (MAMCA) to two medium-sized European cities: Cáceres, Spain, and Coimbra, Portugal. The analysis involved five stakeholder groups (citizens, entrepreneurs, public institutions, mobility operators, and academics) and used a common framework comprising five objectives, fifteen sub-objectives, and eight strategic alternatives for each city. The results show that both cities share strong priorities related to accessibility for vulnerable groups, safety, environmental quality, and public space. However, their preferred strategic pathways differ. In Coimbra, the highest support is associated with pedestrian infrastructure, public space improvements, and integrated spatial planning, whereas in Cáceres, the leading priorities are public transport connectivity, territorial integration, and accessibility for vulnerable groups. The study confirms the usefulness of MAMCA as a transferable decision-support framework for incorporating stakeholder preferences into sustainable mobility planning. Full article

Industrial heritage adaptive reuse occupies a structurally privileged position for degrowth: heritage listing already institutionalises material sufficiency as a regulatory obligation, mandating low intervention and resisting the demolish-and-replace logic of resource-intensive development. Yet this regulatory floor imposes no ceiling on how protected structures are programmed or who benefits; the same statutory instrument can produce different schemes depending entirely on governance. This paper demonstrates that gap through two contrasting UK gasholder adaptive reuse projects: King’s Cross Gasholders in London (private-led, luxury residential) and Granton Gasholder in Edinburgh (council-led community park). Applying De Castro Mazarro et al.’s multi-scalar degrowth framework across building, neighbourhood, and city scales through document analysis and site observations, we identify structural mechanisms explaining why building-scale alignment fails to propagate upward. The findings indicate three governance conditions are necessary to convert the structural degrowth potential of industrial heritage into substantive outcomes: public control over development decisions, community participation extended to strategic priorities rather than design preferences, and explicit integration of degrowth values into upstream planning frameworks. Industrial heritage adaptive reuse is not inherently a degrowth practice, but it is one of the few urban development contexts where the regulatory preconditions for degrowth alignment are already in place. Realising that potential requires governance structures that treat sufficiency and collective wellbeing as binding objectives, not rhetorical claims. Full article

Carbon nanotube field-effect transistors (CNT FETs) hold great promise for extending Moore’s Law, yet their performance is critically limited by excessive off-state leakage, caused by band-to-band tunneling (BTBT) in narrow bandgap CNT channels. In this work, we overcome this long-standing bottleneck by introducing a co-design strategy that integrates a small-diameter HiPco CNT channel with a novel asymmetric gate architecture. This approach strategically reshapes the channel electrostatics to simultaneously suppress the gate-induced drain leakage (GIDL) effect and preserve excellent carrier transport. The efficacy of this strategy is rigorously validated through calibrated technology computer-aided design (TCAD) simulations for both NMOS and PMOS operation, demonstrating an ultralow off-current of 10 fA/µm, an on-current of 1.08 mA/µm, and a record on–off ratio of 1.1 × 10¹¹ for back-gated CNTFETs at the 90 nm node. The design exhibits outstanding scalability: at the scaled 28 nm node with a supply voltage of 0.7 V, the PMOS device achieves 3 mA/µm on-current and 6 pA/µm off-current, maintaining an on–off ratio of 5 × 10⁸. This work establishes a scalable pathway toward femtoampere-level CNT CMOS, addressing the static power challenge in future nano-electronics. Full article

Rhodium is a high-value strategic platinum-group metal extensively applied in automotive exhaust purification, fine chemicals, glass production and high-temperature materials. Restricted by uneven primary resource distribution and volatile market prices, recovering rhodium from secondary resources has become increasingly critical. Solvent extraction is regarded as a promising technology for continuous and selective separation of rhodium, yet direct extraction of Rh(III) from chloride media faces severe industrial limitations. These bottlenecks are mainly attributed to diversified chloro-aqua complexes, kinetic inertness of low-spin Rh(III), strong hydration capacity and polynuclear species generation, while solution aging and inconsistent thermodynamic-experimental results further complicate extraction behaviors. This review systematically summarizes recent advances in rhodium solvent extraction from chloride media, correlating aqueous speciation regulation, activation chemistry, extractant molecular structure and extraction-stripping mechanisms. Special emphasis is placed on SnCl₂-, ascorbic acid-, trichloroacetic acid- and malonate-assisted activation systems, as well as amine-, phosphorus-, sulfur-based, synergistic, ionic-liquid and deep-eutectic-solvent extractants. Key factors affecting extraction efficiency, distribution ratio, selectivity and stripping performance are clarified, and current challenges are outlined. Future research should focus on quantitative speciation analysis, in situ mechanistic characterization, targeted extractant design, and integrated evaluation of extraction, stripping, recyclability, cost and real-feed adaptability, so as to provide theoretical support for efficient and clean rhodium recovery. Full article

This study presents a comprehensive review of more than 100 research papers on sign language recognition (SLR) published between 2020 and 2026. The analysis focuses on deep learning approaches applied to video-based SLR, including spatiotemporal feature extraction, temporal modeling, attention mechanisms, motion-based representations, hybrid frameworks, transfer learning methods and other methods. Particular attention is given to how these methods model spatiotemporal dynamics and capture subtle gesture characteristics in sign language communication. The review highlights several recent developments, such as the introduction of specialized datasets, the emergence of real-time recognition systems, and the integration of multimodal fusion strategies. At the same time, persistent challenges remain, including data scarcity in low-resource sign languages, limited linguistic standardization of datasets, and insufficient model interpretability. The findings underline the importance of developing scalable and generalizable models capable of handling diverse datasets and user variability. The distinct contributions of this review are fourfold: (1) a comprehensive synthesis of over 100 studies published between 2020 and 2026, covering the full spectrum of deep learning architectures for video-based SLR; (2) a structured six-category taxonomy enabling systematic cross-architectural comparison; (3) a comprehensive focus on low-resource sign languages, which remain underrepresented in the existing literature; and (4) a critical analysis of the current benchmark landscape for low-resource sign languages, identifying key gaps and outlining strategic directions for future dataset development. These contributions are intended to guide further research toward more robust, inclusive, and universally applicable SLR systems. Full article

Industrial areas, which represent a specific type of urbanised area with an extremely high concentration of material reserves, can be considered key anthropogenic raw material reservoirs in the context of urban mining. Industrial areas, characterised by a high material density and a specific composition of structural systems, show extraordinary potential for providing secondary raw materials with high material and energy value. This increases the need for their systematic evaluation. The aim of the present study was to define the role of the selected industrial area as a strategic node for secondary raw material extraction, to identify the structure and quality of “urban deposits” in the selected location of the Ostrava–Karviná region (CZ), and to provide an analytical framework for its integration into circular planning processes. The methodological approach is based on a combination of pre-demolition audit, material flow mapping, spatial analysis, and structural element characterisation. It is becoming apparent that industrial areas have a high material density and contain significant amounts of recyclable metals, reinforced concrete elements, etc. These stocks are often concentrated in structural systems with predictable geometries, such as serial assembly prefabricated and steel frames, allowing for more accurate estimates of recoverable volumes. The results show that the incorporation of industrial areas into the process of urban mining can significantly reduce the consumption of primary raw materials, mitigate the environmental impacts associated with the extraction of raw materials, and, at the same time, promote the regeneration of industrial areas (or brownfields) through the planned decomposition of structures. The inclusion of urban mining in urban development strategies and the regeneration of industrial sites leads to the prediction that urban mining is one of the key elements for achieving a material-efficient and low-carbon urban environment. Full article

In the frame of the final analysis of the HERFUSE activities a life cycle assessment (LCA) has been planned to support the performance evaluation of the new Clean Aviation (CA) architectural concepts. The HERFUSE project is focused on designing innovative fuselage and empennages suitable for the future Hybrid-Electric Regional Aircraft (HER) that will contribute to the overall target to reduce greenhouse gas (GHG) emissions. HERFUSE will study the challenges in fuselage and empennage layout, material, components, manufacturing and assembly derived from the integration of the relevant fuselage systems for HER as defined in the strategic research and innovation agenda SRIA for a Hybrid-Electric Regional Aircraft and in HER-01 topic. Full article

Next-generation vaccines are being developed to elicit durable and cross-protective immune responses against diverse pathogens, particularly those targeting the respiratory and enteric systems. By strategically engaging T cell-centric antigen design, mucosal immune engagement, and induction of trained innate immunity, these innovative platforms are expected to reshape the paradigm of immunoprophylaxis and to offer promising avenues for enhanced protection against complex infectious diseases. Conventional antibody-based vaccines, though effective against many infections, often lack the capacity to induce durable or cross-protective immunity at mucosal surfaces. Advances in antigen design, delivery platforms, and adjuvant technologies now facilitate precise activation of tissue-resident memory T cells and enhancement of mucosal secretory IgA responses, thereby achieving sterilizing immunity at barrier surfaces while reinforcing systemic immune protection. Advanced delivery platforms, including lipid nanoparticles, viral vectors, and nano or liposomal carriers, further refine antigen presentation, enhancing stability, targeting, and overall immunogenicity. Concurrently, progress in understanding trained innate immunity highlights opportunities to induce broad, non-antigen-specific protection through epigenetic and metabolic reprogramming of innate cells. The integration of these adaptive and innate mechanisms may enhance early pathogen control, limits transmission, and strengthens defense against variant and antimicrobial-resistant pathogens across diverse populations. However, translating these immunological insights into safe, scalable, and globally accessible vaccines remains a major challenge. This review explores the emerging conceptual framework of next-generation vaccines that demonstrate partial integration of these axes in preclinical models, though human translation and functional synergy require Phase II validation. It highlights progress toward next-generation vaccines leveraging integrated adaptive and innate immune reprogramming for superior protection against respiratory and enteric pathogens. Full article

Adopting a circular economy approach requires new business models, multi-stakeholder engagement, and tailored financial models and mechanisms as core pillars. This paper examines the conditions needed to scale circular economy initiatives in Europe by analysing insights collected from the DECISO project and conducting a comparative analysis of 38 European projects. The study adopts a mixed methods approach that integrates an online stakeholder survey with inputs generated through participatory workshops and discussions of selected use cases. This combined approach is used to identify the main structural barriers limiting the maturity and investment readiness of circular economy projects, such as regulatory complexity, difficulties in accessing funding, and weak stakeholder dialogue mechanisms. The approach was also used for enabling factors that can support development of circular economy. Particular attention is given to the role of project development assistance, modular financing strategies, and de-risking tools, which are highlighted as crucial elements for supporting the technical and economic credibility of projects and attracting public and private investors. The article also identifies and addresses seven unresolved research gaps in the literature, including the lack of interoperable policy instruments, the absence of business models capable of integrating investor expectations, the paucity of integrated methodologies for assessing technical and economic regulatory feasibility, and the need for trust-building procedures. The findings suggest that the transition to a regenerative economy requires a systemic approach based on coherent policies, de-risking financial instruments, collaborative governance, and strategic technical support throughout the project development cycle. Full article

The integration of digital technologies is increasingly recognized as a critical enabler of lean practices in prefabricated construction projects. However, a systematic understanding of the underlying factors that drive this lean–digital transformation remains limited. To address the gap, this study identified 18 factors through an in-depth review of 30 papers and a follow-up questionnaire survey. The factors are divided into five dimensions, i.e., organizational, social, technological, economic and environmental, according to an extended framework of the Socio-Technical Systems (STS) and Technology–Organization–Environment (TOE). These 18 factors were then analyzed via a back propagation (BP) neural network model. The empirical data were collected from 148 practitioners across 11 regions in China where PC industrialization, digital technology adoption, and lean-related practices are relatively mature. These regions were selected because digitalization-driven lean practices are more observable in such contexts, allowing the BP model to capture the comprehensive contribution of key factors more effectively. The findings reveal that the effective implementation of the smart lean practices via digitalization is primarily driven by a systematic process, where greater attention should be directed toward simulation-based process optimization, robust information management, integrated design and construction, lean management systems, and the workers’ digital skills. Although the empirical evidence is derived from relatively mature PC and digital construction markets in China, the identified factors provide reference insights for broader PC projects including less mature regions to make effective measures to improve lean implementation. This study contributes to the existing knowledge body of lean in PC by extending the theories of STS and TOE to advance the understanding of digital drivers. Additionally, the results serve as a reference for stakeholders by informing strategic priorities such as resource allocation for workforce development, advancing the realization of smart lean prefabricated construction. Full article

Silver nanoparticles (AgNPs) have attracted substantial scientific interest in biomedical research owing to their unique physicochemical characteristics, broad-spectrum antimicrobial activity, plasmonic properties, and therapeutic versatility. Although conventional physicochemical synthesis methods enable controlled NPs fabrication, their dependence on hazardous reagents, elevated energy input, and environmentally detrimental processing conditions has stimulated the development of sustainable biogenic alternatives. Biological synthesis utilizing plants, microorganisms, fungi, algae, and purified biomolecules has emerged as an eco-friendly and bio-compatible strategy for AgNP fabrication, enabling simultaneous reduction, stabilization, and intrinsic biofunctionalization of NPs. However, traditional biogenic synthesis remains constrained by limited mechanistic understanding, poor batch reproducibility, inadequate control over physicochemical properties, and challenges in large-scale manufacturing. Recent advances in bioengineering have transformed this field through the integration of metabolic engineering, synthetic biology, microfluidic-assisted synthesis, artificial intelligence-guided process optimization, and continuous-flow biomanufacturing, collectively enabling precision fabrication of biogenic AgNPs with enhanced uniformity, scalability, and functional tunability. Furthermore, strategic surface engineering and functionalization have expanded the applicability of biogenic AgNPs across targeted anticancer therapy, antimicrobial intervention, wound healing, regenerative medicine, drug delivery, and theranostic imaging. Despite these advancements, critical challenges remain regarding nano–bio interactions, toxicological safety, regulatory compliance, and translational scalability. Unlike conventional reviews focused primarily on green synthesis approaches, this review critically highlights emerging bioengineering paradigms that enable programmable, scalable, and precision-controlled biogenic AgNP fabrication. This review comprehensively examines next-generation paradigms and strategies for AgNPs biosynthesis, elucidates the molecular mechanisms governing their formation, highlights emerging functionalization and biomedical application paradigms, and discusses current translational barriers. Forming biogenic composites of AgNPs and heteroatom doped carbon nanodots needs intense research in near future. Full article

Traditional evaluation systems in the current process of urban–rural integration are guided by the goal of “equalization.” They predominantly focus on material facilities and services while neglecting both the integration of socio-cultural dimensions and the disparities between urban and rural areas. Consequently, they are ill-equipped to systematically assess or facilitate the formation of urban–rural communities. To address this gap, this study, grounded in community theory, constructs a county-level comprehensive evaluation framework for urban–rural equivalence that integrates the three dimensions of “material, service, and social” spheres, encompassing material infrastructure, socioeconomic services, and cultural identity. This framework consists of three dimensions, seven criteria, and twenty-one indicators, which are operationalized through statistical data, questionnaire surveys, and field investigations. An empirical application to Xiapu County, Fujian Province, yields a composite urban–rural equivalence index of 0.8184, indicating a moderate level of equivalence, with relatively balanced development across the three dimensions. Furthermore, diagnostic analysis reveals that the key bottlenecks constraining progress toward a higher level of equivalence are not absolute resource shortages but rather the organizational efficiency of spatial linkages, the grassroots-level transmission capacity of public services, and deficiencies in social identity and public participation. Accordingly, differentiated planning response pathways are proposed from the three perspectives of territorial community, governance community, and relational community. By constructing a multidimensional comprehensive evaluation framework, this study advances urban–rural equivalence assessment from mere “disparity description” toward “mechanism diagnosis,” thereby offering a more systematic and operationally feasible evaluation tool and strategic reference for county-level urban–rural integration. Full article