Search Results (1,329)

Existing deep-learning-based motor imagery (MI) electroencephalogram (EEG) decoding methods face challenges in generalizing across sessions and providing channel-level physiological interpretability. These limitations hinder the practical application of MI-EEG systems. Accordingly, DO-PI-EATCNet (Dream-Optimization-Enhanced, Physics-Inspired, Efficient-Attention Temporal Channel Network) is proposed to improve generalization and interpretability in MI-EEG classification. Unlike models that simply combine multiple components, DO-PI-EATCNet assigns distinct roles to feature representation, temporal channel modeling, temporal regularization, and channel compactness. Latent-Projected Attention (LPA) enhances spatiotemporal discriminability by aligning attention in a low-dimensional latent space, and Temporal Channel Cascaded Collaborative Attention (TCCA) refines dependencies between time and channels. Fractional-Order Difference Temporal Consistency Loss (FD-TCL) is introduced as a neurodynamics-inspired temporal regularizer to reduce high-frequency fluctuations in prediction sequences and improve within-subject cross-session prediction stability. The Multi-Population Dream Optimization Algorithm (MPDOA) is used for channel selection to obtain a compact EEG channel subset and reduce computational load, although it introduces a slight accuracy decrease compared with the uncompressed full model. Under a within-subject cross-session protocol on the BCI Competition IV-2a four-class MI dataset, the final compact model achieves an average accuracy of 84.4% and Cohen’s κ of 0.790, outperforming the reimplemented baselines. Compared with the uncompressed LPA-TCCA-FD-TCL variant, MPDOA slightly decreases accuracy from 84.9% to 84.4%, but reduces EEG channels from 22 to about 15 and decreases MACs by 27%. Scalp topographies and selected-channel visualizations provide qualitative support for channel-level anatomical plausibility, as the selected electrodes are mainly located over expected sensorimotor-related regions, while t-SNE offers a descriptive visualization of the learned feature distributions. Full article

Objective and reproducible diagnosis of attention-deficit/hyperactivity disorder (ADHD) remains challenging because of the limited availability of reliable electroencephalography (EEG) biomarkers and the high variability of neural signals. This study proposes a computational framework for ADHD detection based on dynamic functional connectivity and network-index modeling. Multichannel EEG recordings were transformed into temporal connectivity graphs using sliding-window correlations of band-limited amplitude envelopes. Several network-index models were evaluated, including linear, graph-based, recurrent, and hybrid spatio-temporal approaches. The proposed Hybrid Spatio-Temporal Graph Transformer demonstrated moderate, yet reproducible, subject-level classification performance. On the independent test set, the model achieved an accuracy of 63.16%, a balanced accuracy of 62.22%, a sensitivity of 80.00%, a specificity of 44.44%, an F1-score of 69.57%, and an AUC-ROC of 0.7444. Additional analysis of the derived network index demonstrated moderate intergroup separability, with a mean index shift of 1.16, Cohen’s d = 0.73, Pearson’s r = 0.36, and distribution overlap = 0.72. These findings suggest that the proposed framework captures informative spatio-temporal EEG connectivity patterns associated with ADHD; however, the model’s diagnostic applicability should be considered preliminary and requires validation in larger independent cohorts. Full article

Time-Sensitive Networking (TSN) with Cyclic Queuing and Forwarding (CQF) is a critical mechanism for ensuring deterministic forwarding. However, existing incremental schedulers typically rely on single-dimensional heuristics, which fail to address the coupled impact of traffic characteristics and spatiotemporal resource distribution. This limitation leads to suboptimal scheduling success, especially under complex topologies and high network loads. To address this, we propose TMCOA–MFS, a joint incremental scheduling framework that integrates the Triple-Mode Cooperative Optimization Algorithm (TMCOA) with a Multi-Feature Scheduling (MFS) strategy. The logic of our approach is twofold: First, to balance spatial resource distribution, we introduce the TMCOA—inspired by table-tennis offensive–defensive behaviors—to optimize path selection by minimizing port-load variance and escaping local optima through a three-mode population partition. Second, building upon the optimized spatial paths, the MFS strategy is employed to resolve temporal scheduling conflicts. By computing a composite priority score that accounts for path hops, offset configuration difficulty, and flow size, MFS enables a robust incremental offset search with integrated feasibility checking. Extensive simulations on benchmark functions and diverse TSN scenarios demonstrate that the TMCOA offers superior convergence and stability. More importantly, the integrated TMCOA–MFS framework significantly enhances scheduling success rates and load balancing, effectively overcoming the bottlenecks of high-load and topologically complex environments. Full article

Accurate short-term traffic prediction is a key requirement for modern traffic management systems, yet many existing approaches remain focused on offline evaluation and do not address the challenges of continuous real-time deployment. In this work, we present a context-aware spatiotemporal graph convolutional network (STGCN) framework designed for low-latency, scalable traffic forecasting under operational conditions. The proposed approach integrates structural information from the road network, temporal regularities derived from historical data, and a residual correction mechanism trained on systematic prediction errors observed during real-time operation. The framework is designed to remain lightweight, enabling continuous minute-level inference without computational overhead that would hinder long-term deployment. The methodology is evaluated in two real-world case studies of different scale and complexity. In Thessaloniki, Greece, multiple forecasting models are evaluated across different temporal resolutions using one-minute speed data, with the proposed STGCN selected for real-time deployment. A residual correction module trained on historical prediction errors further improves real-time forecasting accuracy compared to the baseline STGCN deployment. Scalability is further demonstrated in the South Holland region of the Netherlands, where the same architecture is applied to a larger network and extended to multi-horizon forecasting. Results show that the proposed framework achieves competitive predictive performance while maintaining low computational cost, and that incorporating residual error learning provides a robust and practical solution for improving forecasting accuracy in real-world deployments. These findings highlight the importance of combining domain-specific modeling with operational considerations in traffic prediction systems. Full article

Despite decades of therapeutic advances, cardiovascular diseases remain the leading cause of global mortality, underscoring the need for strategies that move beyond untargeted systemic pharmacotherapy. Synthetic biology introduces a programmable therapeutic paradigm in which engineered gene circuits can sense, compute, and respond to pathological signals with spatiotemporal precision. This review examines the current progress of synthetic gene circuits for cardiovascular therapy, organized across three domains of clinical relevance. The first domain comprises circuits engineered for direct cardiac applications, from inducible switches to classifier systems. This discussion is further expanded by exploring circuits that indirectly target cardiovascular disease; these circuits address upstream risk factors such as cholesterol dysregulation and chronic inflammation. Looking ahead, the focus shifts to orthogonal architectures pioneered in other therapeutic contexts that hold promise for future cardiac applications. This review further discusses the emerging role of computational tools, including gene regulatory network inference and foundation models, in accelerating target discovery. Finally, a modified Design-Build-Test-Learn framework is proposed to overcome translational bottlenecks, thus paving the way for next-generation cardiac therapeutics. Full article

Grassland fire is one of the major disasters threatening regional ecological security. Its occurrence, development, and spread are closely related to the spatial distribution and coverage of surface vegetation and snow cover across grassland areas. As the primary combustible fuel source, higher vegetation coverage increases fuel load and continuity, thereby directly determining grassland fire danger levels and accelerating fire spread velocity. In contrast, snow cover imposes an indirect regulatory effect on the spatiotemporal pattern of fire danger factors: it lowers surface temperature, raises near-surface humidity, and restricts the germination and growth of herbaceous vegetation in cold seasons, which effectively reduces available combustible materials and weakens regional fire hazard conditions. Therefore, accurately obtaining the coverage status of vegetation (direct combustible fuel factor) and snow cover (indirect fire-regulating factor) in complex grassland scenarios is the essential premise for reliable grassland fire danger monitoring, early warning, disaster prevention and control, and regional ecological management. Aiming at the practical problems in complex grassland scenarios (such as undulating terrain, uneven vegetation growth, large differences in snow depth, and complex lighting conditions), including difficulty in extracting vegetation and snow-covered areas, blurred and confusing boundaries, and low accuracy in coverage calculation, which seriously restrict the technical bottleneck of precise monitoring of grassland fire danger factors, this study takes near-ground images collected by grassland fire danger factor monitoring stations as the core data source, and proposes an improved UNet image segmentation model combined with image segmentation technology and deep learning methods to realize precise extraction of vegetation and snow-covered areas and efficient calculation of coverage in complex scenarios. To improve the model’s feature extraction ability, boundary localization accuracy, and reduce model parameters and computational overhead, the CBAM-ASPP (Convolutional Block Attention Module—Atrous Spatial Pyramid Pooling) module is integrated at the end of the encoding path. The attention mechanism is used to enhance the weight of key features, and the multi-scale receptive field of atrous spatial pyramid pooling is utilized to strengthen the model’s ability to fuse features of vegetation and snow areas of different scales. The residual attention mechanism is introduced in the upsampling stage to effectively alleviate the gradient disappearance problem, improve the model’s ability to accurately locate the boundaries of vegetation and snow areas, and reduce segmentation errors. In the training process, a dynamically weighted hybrid loss function is adopted to dynamically adjust the weights according to the segmentation difficulty of different types of samples during training, optimize the model training effect, and improve the segmentation accuracy and generalization ability. Experiments were conducted using near-ground images of typical complex grassland scenarios as the dataset, and the performance of the proposed model was verified through comparative experiments. The results show that in the vegetation segmentation task, the mean Intersection over Union (mIoU) of the model reaches 84.70%, and the accuracy rate is 91.28%, which are 1.48 and 1.58 percentage points higher than those of the standard UNet model, respectively. In the snow segmentation task, the mIoU of the model reaches 92.74%, and the accuracy rate is 94.19%, which are 2.39 and 2.36 percentage points higher than those of the standard UNet model, respectively. At the same time, the number of parameters of the model is reduced by 12.85% compared with the standard UNet. Also, its comprehensive performance is significantly better than that of mainstream image segmentation models such as FCN, SegNet, and DeepLabv3+. Based on the standardized time-series data retrieved by the optimized segmentation model, this study further constructs a Grassland Fire Risk Index (GFRI) using the Analytic Hierarchy Process (AHP). Pearson correlation verification confirms that the GFRI has an extremely significant positive correlation with historical fire frequency, accurately capturing the seasonal dynamic rhythm of regional grassland fire occurrence. This integrated framework of intelligent segmentation and fire risk quantification provides a reliable technical solution for grassland fire factor monitoring, dynamic fire risk assessment, early warning systems, and refined regional ecological management. Full article

To mitigate large-scale blackout risks in urban distribution systems under typhoon-induced extreme weather and to reduce post-disaster restoration costs, this study proposes a resilience-oriented spatiotemporal co-optimization framework integrating transportation networks, power grids, and distributed energy resources. First, a city-scale typhoon spatiotemporal model is established, integrating static wind field, dynamic evolution, and trajectory-based mobility with urban-geometry-driven wind speed correction to characterize the spatiotemporal progression of extreme wind hazards. Second, the time-varying failure rates of distribution network components are quantified by explicitly accounting for network topology correlations, while the spatiotemporal dispatchability and output characteristics of distributed resources under disaster conditions are systematically modeled. Third, a pre-disaster proactive deployment model is formulated to minimize load curtailment costs and resource allocation expenditures. The model integrates active network reconfiguration with coordinated placement of distributed generation (DG) and mobile energy storage systems (MESSs), enabling resilience-enhancing pre-positioning strategies. Subsequently, a post-disaster restoration scheduling model is developed with the objective of minimizing unserved load. By embedding traffic flow constraints and optimal path computation under disrupted transportation conditions, the proposed framework realizes spatiotemporal coordination among MESSs, DG, and electric vehicles (EVs), thereby accelerating system-level recovery. Finally, the effectiveness of the proposed strategy is validated on a 51-node urban distribution system located in eastern coastal China, demonstrating significant improvements in restoration performance and resilience enhancement. Full article

Interfacial stress concentration induced by curing shrinkage during the manufacturing of epoxy resin is a primary trigger for micro-nano defect formation and electrical performance degradation in power equipment. To address the computational complexity of traditional viscoelastic models and the thermoelastic behavior wherein the stiffness of the epoxy resin varies with temperature during curing, this paper proposes an improved viscoelastic constitutive model incorporating a thermo-elastic factor. By coupling curing kinetics, heat conduction, chemical shrinkage, and mechanical effects, a multi-physics simulation framework is constructed to describe the complete epoxy curing process, thereby revealing the spatiotemporal evolution of curing stress deformation. To verify the model’s accuracy, an in situ monitoring system based on Fiber Bragg Grating (FBG) sensors was established. A temperature compensation method was utilized to effectively decouple temperature and stress within the complex exothermic curing environment. This study reveals a significant strain gradient effect during the resin curing process. Experimental measurements indicate strains of 21,609 με and 5800 με at the interface and surface, respectively, with numerical simulations exhibiting high agreement with the experimental data. This research not only provides an efficient simulation approach for predicting curing stress but also offers a theoretical basis for the crack-resistant structural design of high-performance epoxy-based power equipment. Full article

In osteopetrotic mice with homozygous inactivating mutations in the colony stimulating factor 1 (Csf1^op/op) or its receptor (Csf1r^−/−) gene, teeth fail to erupt due to severe reduction in osteoclastogenesis. Dental abnormalities have been described in the unerupted teeth of these models, but it remains unclear whether these defects arise from direct roles of CSF1R in odontogenesis or indirectly from impaired bone remodeling associated with failed eruption. Here, we examined the spatiotemporal expression of CSF1R during tooth development and inhibited CSF1R pharmacologically in utero using PLX5622 during early stages of tooth morphogenesis. Teeth and surrounding bone were analyzed at embryonic and postnatal stages using histology and high-resolution micro-computed tomography. Embryonic CSF1R inhibition resulted in reproducible abnormalities in incisor and molar morphology that were evident before and after birth and were associated with loss of normal bone remodeling at the tooth–bone interface. In contrast, postnatal CSF1R inhibition did not affect the structure or continuous growth of adult incisors. Together, these findings demonstrate a temporally restricted, indirect role for CSF1R in odontogenesis that is independent of tooth eruption and associated with remodeling of the bony crypts surrounding developing teeth by CSF1R-dependent cells. Full article

Real-time crash risk assessment is a key component of proactive road safety management, enabling the identification of hazardous conditions within short temporal intervals before crashes occur. Traditional crash-based models are unsuitable for such applications due to the rarity, reporting delay, and stochastic nature of crash data. Traffic conflicts, capturing near-miss interactions between road users, provide a practical alternative for real-time safety analysis. Over the past decade, numerous modelling approaches have been developed to translate conflict information into crash risk estimates; however, the literature remains fragmented and lacks a unified analytical synthesis. This review presents a state-of-the-art, model-centric analysis of conflict-based approaches, classifying them into five paradigms: statistical/regression-based, Bayesian, extreme value theory (EVT), machine learning (ML), and hybrid models. Beyond classification, the study conducts a structured cross-paradigm comparison across key dimensions, including conflict representation, data characteristics, temporal modelling, uncertainty treatment, validation strategies, computational complexity, and operational readiness. The paradigms are further interpreted through the complementary lenses of conflict frequency and severity. The review identifies key research gaps, including fragmented conflict definitions, challenges in modelling rare and extreme events, incomplete treatment of uncertainty and spatiotemporal dynamics, and limitations in validation, transferability, and deployment. Emerging research directions include standardized and adaptive conflict indicators, EVT–machine learning integration, integrated uncertainty-aware frameworks, advanced spatiotemporal modelling, transferable models, and scalable real-time implementation. By combining structured evidence mapping and cross-paradigm synthesis, this study supports model selection, development, and deployment for dynamic crash risk assessment. Full article

The attribution of systemic financial stress to specific market sectors requires metrics that are faithful to the model’s computations, statistically consistent, and connected to a physically meaningful measure of directed information flow. This paper addresses all three requirements through information geometry, contributing to SDGs 7, 8, 9, and 17 through an entropic causal chain linking energy infrastructure failure to financial market stress. We conjecture and empirically verify the Entropy–Saliency Equivalence: Metabolic Saliency is an asymptotically unbiased estimator of the local Kullback–Leibler divergence between stressed and resting sector return distributions, with bias decaying at a parametric rate under Gaussian regularity conditions. The finite-sample bias–variance decomposition of the Kraskov–Stögbauer–Grassberger transfer entropy estimator is derived, establishing a minimax-optimal convergence rate. A novel metric, the Spatio-Temporal Information Flux (STIF), quantifies directed inter-sector stress transmission in bits per trading day, providing a bootstrap-calibrated audit trail aligned with the South African Financial Sector Regulation Act and MiFID II. Empirical validation on the JSE canonical panel (87 securities, 2857 trading days, 2015–2026) with Eskom load-shedding stages as exogenous stress injectors confirms the equivalence ($R^2=0.810$, $\widehat{\rho }=0.90$), with walk-forward $R^2=0.789$ and placebo $R^2=0.081$ ruling out estimation artefacts. The energy sector is identified as the primary stress transmitter during Stage 4+ Eskom events (STIF rising from 0.14 to 0.43 bits/day, directional asymmetry ratio 4.7). Robustness checks confirm stability across non-Gaussian securities and rolling transfer entropy windows. Full article

This paper presents a robust and efficient mmWave radar-based human activity recognition (HAR) framework optimized for practical real-time indoor deployment. Addressing computational inefficiencies and limited recognition scopes in existing systems, the framework introduces two core contributions: Multi-class Spatio-Temporal Network (MuST-Net), a lightweight, multi-class network, and an online detection process for enhanced temporal stability. MuST-Net utilizes a hybrid 2D convolutional neural network and temporal convolutional network architecture to recognize seven distinct classes, significantly broadening the system’s recognition repertoire. The online detection process implements a novel sliding-window post-processing chain that employs an activity-buffering mechanism, which maintains temporal continuity and effectively suppresses spurious detections at activity boundaries. Experimental results demonstrate the superior performance of our unified framework, attaining over 98.6% accuracy for multi-class classification by MuST-Net and achieving at least 97% accuracy for activity detection and a crucial 100% recall for fall detection. Robustness is validated across three distinct indoor environments and nine subjects—with two of the three sites entirely unseen during training—confirming strong generalization under installation, environment, and subject variations. Full article

Geothermal energy extraction, hydrocarbon recovery, and CO₂ geological sequestration are frequently hindered by interfacial barriers and slow mass transfer. While high-power ultrasound offers a sustainable, purely physical method for reservoir stimulation, its field effectiveness remains debated because traditional macroscopic experiments fail to isolate mechanisms like acoustic streaming and cavitation. This review systematically examines acoustic mechanisms in porous media via microfluidic visualization, focusing on pore-scale fluid dynamics during enhanced oil recovery, hydrate dissociation, and CO₂ sequestration. Microscopic evidence reveals that fluid transport mechanisms depend heavily on pore geometry and local acoustic intensity. In wider channels, nonlinear acoustic flow provides sustained, directed convection to strip away concentration boundary layers; in narrow throats, microjets and pulsed stresses generated by transient cavitation are responsible for physically breaking capillary barriers. The spatiotemporal synergy of these mechanisms is critical for multiphase fluid transport in tight porous networks. Pore geometry serves not only as the application context but also as a core physical variable. To translate microfluidic results into reservoir-scale applications, future research must address two-dimensional simplifications, thermodynamic discrepancies under high-temperature and high-pressure conditions, and bubble cluster interactions, alongside the development of adaptive frequency-modulated control and multiscale computational models. Full article

Traditional linear models in urban informatics struggle to capture the complex, non-linear spatial non-stationarity inherent in metropolitan housing markets. To overcome these constraints, this study introduces a data-driven computational framework integrating a Spatio-Temporal Graph Convolutional Network (STGCN) with gradient-based Explainable Artificial Intelligence (XAI) and Geographically Weighted Regression (GWR). This framework is empirically tested using 217,598 apartment transactions in Busan, the Republic of Korea, augmented with high-resolution micro-demographic grids and Digital Elevation Model (DEM) topographical data. Utilizing unsupervised K-Means clustering, the region is spatially stratified into a dense Urban Core and a dispersed Suburban Periphery. The STGCN demonstrates overwhelming predictive superiority ($R^2=0.802$) over the traditional Spatial Error Model ($R^2=0.437$). Crucially, gradient-based XAI and localized GWR coefficients successfully unspool the deep learning “black box,” visualizing hyper-localized economic realities that global linear models obscure. The analysis expose stark regional market segmentation driven by environmental topography, mathematically quantifying non-linear dynamics such as coastal high-floor premiums, severe mountainous altitude penalties, and latent urban reconstruction premiums. Ultimately, this research bridges the gap between predictive computational power and spatial economic interpretability, offering a robust informatics framework for equitable urban planning. Full article

Reliable onboard fault detection and diagnosis (FDD) is essential for autonomous small-satellite constellation operations. The satellite telemetry streams are typically high-dimensional, strongly time-correlated, and severely imbalanced. These characteristics make rare but critical faults hard to recognize. To address these issues, this paper proposes an imbalance-aware spatiotemporal diagnostic framework based on three-dimensional convolutional neural networks (3D-CNNs). Multivariate telemetry is first converted into structured spatiotemporal volumes via sliding-window segmentation and grid-based embedding. This enables the model to jointly learn temporal evolution and cross-parameter coupling patterns. A lightweight residual 3D-CNN is developed to enable end-to-end multi-class classification. In addition, a class-balanced focal objective function is introduced to mitigate class-imbalance issues and enhance sensitivity to minority fault modes. The Lumelite series satellite telemetry dataset, comprising 23 fault types, is constructed for training and evaluation. The proposed lightweight residual 3D-CNN is benchmarked against long short-term memory–random forest (LSTM-RF), support vector machine (SVM), 2D-CNN, CNN-LSTM, and residual neural network models. Experimental results show that the proposed algorithm has the highest overall accuracy and Macro-F1 score. It also obtains higher Recall for low-frequency faults. The computational complexity studies indicate that the proposed algorithm has promising potential for real-time satellite health monitoring. Full article