Search Results (2,386)

Rainstorm floods constitute one of the major natural hazards threatening the safe and stable operation of power grid facilities. Constructing a rapid and accurate prediction model is of great significance in order to enhance the disaster prevention capacity of the power grid. This study proposes a rapid prediction model for urban rainstorm flood targeting power grid facilities based on deep learning. The model utilizes computational results of high-precision mechanism models as data-driven input and adopts a dual-branch prediction architecture of space and time: the spatial prediction module employs a multi-layer perceptron (MLP), and the temporal prediction module integrates convolutional neural network (CNN), long short-term memory network (LSTM), and attention mechanism (ATT). The constructed water dynamics model of the right bank of Liangshui River in Fengtai District of Beijing has been verified to be reliable in the simulation of the July 2023 (“23·7”) extreme rainstorm event in Beijing (the July 2023 event), which provides high-quality training and validation data for the deep learning-based surrogate model (SM model). Compared with traditional high-precision mechanism models, the SM model shows distinctive advantages: the R² value of the overall inundation water depth prediction of the spatial prediction module reaches 0.9939, and the average absolute error of water depth is 0.013 m; the R² values of temporal water depth processes prediction at all substations made by the temporal prediction module are all higher than 0.92. Only by inputting rainfall data can the water depth at power grid facilities be output within seconds, providing an effective tool for rapid assessment of flood risks to power grid facilities. In a word, the main contribution of this study lies in the proposal of the SM model driven by the high-precision mechanism model. This model, through a dual-branch module in both space and time, has achieved second-level high-precision prediction from rainfall input to water depth output in scenarios where the power grid is at risk of flooding for the first time, providing an expandable method for real-time simulation of complex physical processes. Full article

Accurate traffic flow prediction is a core component of intelligent transportation systems, supporting proactive traffic management, resource optimization, and sustainable urban mobility. However, urban traffic networks exhibit heterogeneous multi-scale periodic patterns and time-varying spatial interactions among road segments, which are not sufficiently captured by many existing spatio-temporal forecasting models. To address this limitation, this paper proposes PDR-STGCN (Periodicity-Aware Dynamic Relational Spatio-Temporal Graph Convolutional Network), an enhanced STGCN framework that jointly models multi-scale periodicity and dynamically evolving spatial dependencies for traffic flow prediction. Specifically, a periodicity-aware embedding module is designed to capture heterogeneous temporal cycles (e.g., daily and weekly patterns) and emphasize dominant social rhythms in traffic systems. In addition, a dynamic relational graph construction module adaptively learns time-varying spatial interactions among road nodes, enabling the model to reflect evolving traffic states. Spatio-temporal feature fusion and prediction are achieved through an attention-based Bidirectional Long Short-Term Memory (BiLSTM) network integrated with graph convolution operations. Extensive experiments are conducted on three datasets, including Metro Traffic Los Angeles (METR-LA), Performance Measurement System Bay Area (PEMS-BAY), and a real-world traffic dataset from Guizhou, China. Experimental results demonstrate that PDR-STGCN consistently outperforms state-of-the-art baseline models. For next-hour traffic forecasting, the proposed model achieves average reductions of 16.50% in RMSE, 9.00% in MAE, and 0.34% in MAPE compared with the second-best baseline. Beyond improved prediction accuracy, PDR-STGCN reveals latent spatio-temporal evolution patterns and dynamic interaction mechanisms, providing interpretable insights for traffic system analysis, simulation, and AI-driven decision-making in urban transportation networks. Full article

While 3D Gaussian Splatting (3DGS) has significantly advanced large-scale 3D reconstruction and novel view synthesis, it still suffers from high memory consumption and slow training speed. To address these issues without compromising reconstruction quality, we propose a novel 3DGS-based framework tailored for large-scale scenes. Specifically, we introduce a visibility-aware camera selection strategy within a divide-and-conquer training approach to dynamically adjust the number of input views for each sub-region. During training, a spatially aware densification strategy is employed to improve the reconstruction of distant objects, complemented by depth regularization to refine geometric details. Moreover, we apply an enhanced Gaussian pruning method to re-evaluate the importance of each Gaussian, prune redundant Gaussians with low contributions, and improve efficiency while reducing memory usage. Experiments on multiple large-scale scene datasets demonstrate that our approach achieves superior performance in both quality and efficiency. With its robustness and scalability, our method shows great potential for real-world applications such as autonomous driving, digital twins, urban mapping, and virtual reality content creation. Full article

Adipose tissue thermogenesis is a promising strategy to counter obesity and metabolic disease, but sustained activation of thermogenic adipocytes elevates oxidative and lipid-peroxidation stress, increasing susceptibility to ferroptotic cell death. Existing models often treat redox buffering, hypoxia signaling and ferroptosis as separate processes, which cannot explain why similar interventions—such as antioxidants, β-adrenergic agonists or iron modulators—alternately enhance thermogenesis or precipitate tissue failure. Here, we propose the Redox–Thermogenesis–Ferroptosis Compass (RTF-Compass) as a framework that maps adipose depots within a space defined by ferroptosis resistance capacity (FRC), ferroptosis signaling intensity (FSI) and HIF-1α-dependent hypoxic tone. Within this space, thermogenic output follows a hormetic, inverted-U trajectory, with a Thermogenic Ferroptosis Window (TFW) bounded by two failure states: a Reductive-Blunted state with excessive antioxidant buffering and weak signaling, and a Cytotoxic state with high ferroptotic pressure and inadequate defense. We use this model to reinterpret genetic, nutritional and pharmacological studies as state-dependent vectors that move depots through FRC–FSI–HIF space and to outline principles for precision redox medicine. Although the TFW is represented as coordinates in FRC–FSI–HIF space, we use ‘Compass’ to denote a coordinate framework in which perturbations act as vectors that orient depots toward thermogenic or cytotoxic outcomes. Finally, we highlight priorities for testing the model in vivo, including defining lipid species that encode ferroptotic tone, resolving spatial heterogeneity within depots and determining how metabolic memory constrains reversibility of pathological states. Full article

Background: Alzheimer’s disease (AD) features progressive cognitive decline and amyloid-beta (Aβ) accumulation. Insulin resistance in type 2 diabetes mellitus (T2DM) is increasingly recognised as a mechanistic link between metabolic dysfunction and neurodegeneration. Although sodium–glucose cotransporter-2 inhibitors (SGLT2is) have established glycaemic and cardioprotective benefits, their neuroprotective role remains less well defined. Objectives: This systematic review examines animal studies on the neuroprotective effects of SGLT2i in T2DM and AD models. Methods: A literature search was conducted across the Web of Science, Scopus, and PubMed databases, covering January 2014 to November 2024. Heterogeneity was assessed with I², and data were pooled using fixed-effects models, reported as standardised mean differences with 95% confidence intervals. We focus on spatial memory performance as measured by the Morris Water Maze (MWM) test, including escape latency and time spent in the target quadrant, as the primary endpoints. The secondary endpoints of Aβ accumulation, oxidative stress, and inflammatory markers were also analysed and summarised. Results: Twelve studies met the inclusion criteria for this review. A meta-analysis showed that SGLT2i treatment significantly improved spatial memory by reducing the escape latency in both T2DM and AD models. In addition, SGLT2i yielded a significant improvement in spatial memory, as indicated by an increased target quadrant time for both T2DM and AD. Furthermore, SGLT2i reduced Aβ accumulation in the hippocampus and cortex, which met the secondary endpoint; the treatment also lessened oxidative stress and inflammatory markers in animal brains. Conclusions: Our findings indicate that SGLT2is confer consistent neuroprotective benefits in experimental T2DM and AD models. Full article

The abrupt COVID-19 lockdown in early 2020 offered a unique natural experiment to examine vegetation productivity responses to sudden declines in human activity. Although vegetation often responds to environmental changes with time lags, how such lags operate under short-term, intensive disturbances remains unclear. This study combined multi-source environmental data with an interpretable machine learning framework (XGBoost-SHAP) to analyze spatiotemporal variations in net primary productivity (NPP) across the Beijing-Tianjin-Hebei region during the strict lockdown (March–May) and recovery (June–August) periods, using 2017–2019 as a baseline. Results indicate that: (1) NPP showed a significant increase during lockdown, with 88.4% of pixels showing positive changes, especially in central urban areas. During recovery, vegetation responses weakened (65.31% positive) and became more spatially heterogeneous. (2) Integrating lagged environmental variables improved model performance (R² increased by an average of 0.071). SHAP analysis identified climatic factors (temperature, precipitation, radiation) as dominant drivers of NPP, while aerosol optical depth (AOD) and nighttime light (NTL) had minimal influence and weak lagged effects. Importantly, under lockdown, vegetation exhibited stronger immediate responses to concurrent temperature, precipitation, and radiation (SHAP contribution increased by approximately 7.05% compared to the baseline), whereas lagged effects seen in baseline conditions were substantially reduced. Compared to the lockdown period, anthropogenic disturbances during the recovery phase showed a direct weakening of their impact (decreasing by 6.01%). However, the air quality improvements resulting from the spring lockdown exhibited a significant cross-seasonal lag effect. (3) Spatially, NPP response times showed an “urban-immediate, mountainous-delayed” pattern, reflecting both the ecological memory of mountain systems and the rapid adjustment capacity of urban vegetation. These findings demonstrate that short-term removal of anthropogenic disturbances shifted vegetation responses toward greater immediacy and sensitivity to environmental conditions. This offers new insights into a “green window period” for ecological management and supports evidence-based, adaptive regional climate and ecosystem policies. Full article

Alzheimer’s Disease (AD) is an advanced brain illness that affects millions of individuals across the world. It causes gradual damage to the brain cells, leading to memory loss and cognitive dysfunction. Although Magnetic Resonance Imaging (MRI) is widely used in AD diagnosis, the existing studies rely solely on the visual representations, leaving alternative features unexplored. The objective of this study is to explore whether MRI sonification can provide complementary diagnostic information when combined with conventional image-based methods. In this study, we propose a novel dual-stream multimodal framework that integrates 2D MRI slices with their corresponding audio representations. MRI images are transformed into audio signals using a multi-scale, multi-orientation Gabor filtering, followed by a Hilbert space-filling curve to preserve spatial locality. The image and sound modalities are processed using a lightweight CNN and YAMNet, respectively, then fused via logistic regression. The experimental results of the multimodal achieved the highest accuracy in distinguishing AD from Cognitively Normal (CN) subjects at 98.2%, 94% for AD vs. Mild Cognitive Impairment (MCI), and 93.2% for MCI vs. CN. This work provides a new perspective and highlights the potential of audio transformation of imaging data for feature extraction and classification. Full article

Healthcare has been fundamentally changed by the expansion of IoT, which enables advanced diagnostics and continuous monitoring of patients outside clinical settings. Frequently interconnected medical devices often encounter resource limitations and lack comprehensive security safeguards. Therefore, such devices are prone to intrusions, with DDoS attacks in particular threatening the integrity of vital infrastructure. To safe guard sensitive patient information and ensure the integrity and confidentiality of medical devices, this article explores the critical importance of robust security measures in healthcare IoT systems. In order to detect DDoS attacks in healthcare networks supported by WBSN-enabled IoT devices, we propose a hybrid detection model. The model utilizes the advantages of Long Short-Term Memory (LSTM) networks for modeling temporal dependencies in network traffic and Convolutional Neural Networks (CNNs) for extracting spatial features. The effectiveness of the model is demonstrated by simulation results on the CICDDoS2019 datasets, which indicate a detection accuracy of 99% and a loss of 0.05%, respectively. The evaluation results highlight the capability of the hybrid model to reliably detect potential anomalies, showing superior performance over leading contemporary methods in healthcare environments. Full article

Di-2-ethylhexyl phthalate (DEHP) is a widely used plasticizer with recognized sex-dependent neurotoxicity. However, research on adult neurotoxicity is scarce, especially in females. In this study, adult female rats were exposed to a high-dose experimental model of DEHP (500 mg/kg/day) for 28 days to systematically evaluate hippocampal neurotoxicity. We found that DEHP exposure significantly impaired spatial learning and memory. Transcriptomics revealed enrichment in oxidative stress, complement activation, and neurodegenerative pathways. Specifically, cellular and molecular analyses showed that DEHP induced mitochondrial structural defects and elevated markers of oxidative damage (8-OHdG and 3-NT). While the upregulation of mitochondrial and antioxidant proteins (COX4I1, SOD2, and NQO1) indicated an attempted compensatory response, it remained inadequate to restore redox homeostasis. Under this neurotoxic microenvironment, DEHP triggered early neurogenesis, marked by the upregulation of SOX2 and DCX; however, NeuN levels remained unchanged, suggesting that this compensatory effort failed to expand the mature neuronal population. Ultimately, these pathological processes culminated in neurodegeneration, as evidenced by reduced synaptic proteins, suppressed Olig1/2 expression, and increased tau phosphorylation. Collectively, this study provides a comprehensive neurotoxic profile of DEHP in adult female rats, filling a research gap in this field. Full article

The formation and stability of river ice covers in regulated waterways are critical for uninterrupted hydro-electric operations. This study investigates the modelling of ice cover development in the Beauharnois Canal along the St. Lawrence River with the presence and absence of ice booms. Ice booms are deployed in this canal to promote the rapid formation of a stable ice cover during freezing events, minimizing disruptions to dam operations. Remote sensing data were used to assess the spatial extent and temporal evolution of an ice cover and to calibrate the river ice model RIVICE. The model was applied to simulate ice formation for the 2019–2020 ice season, first for the canal with a series of three ice booms and then rerun under a scenario without booms. Comparative analysis reveals that the presence of ice booms facilitates the development of a relatively thinner and more uniform ice cover. In contrast, the absence of booms leads to thicker ice accumulations and increased risk of ice jamming, which could impact water management and hydroelectric generation operations. Computational efficiencies of the RIVICE model were also sought. RIVICE was originally compiled with a Fortran 77 compiler, which restricted modern optimization techniques. Recompiling with NVFortran significantly improved performance through advanced instruction scheduling, cache management, and automatic loop analysis, even without explicit optimization flags. Enabling optimization further accelerated execution, albeit marginally, reducing redundant operations and memory traffic while preserving numerical integrity. Tests across varying ice cross-sectional spacings confirmed that NVFortran reduced runtimes by roughly an order of magnitude compared to the original model. A test GPU (Graphics Processing Unit) version was able to run the data interpolation routines on the GPU, but frequent data transfers between the CPU (Central Processing Unit) and GPU caused by shared memory blocks and fixed-size arrays made it slower than the original CPU version. Achieving efficient GPU execution would require substantial code restructuring to eliminate global states, adopt persistent data regions, and parallelize at higher level loops, or alternatively, rewriting in a GPU-friendly language to fully exploit modern architectures. Full article

High-precision prediction of the crystal diameter during the growth of electronic-grade silicon single crystals is a critical step for the fabrication of high-quality single crystals. However, the process features high-temperature operation, strong nonlinearities, significant time-delay dynamics, and external disturbances, which limit the accuracy of conventional mechanism-based models. In this study, mechanism-based models denote physics-informed heat-transfer and geometric models that relate heater power and pulling rate to diameter evolution. To address this challenge, this paper proposes a hybrid deep learning model combining a convolutional neural network (CNN), a bidirectional long short-term memory network (BiLSTM), and self-attention to improve diameter prediction during the shoulder-formation and constant-diameter stages. The proposed model leverages the CNN to extract localized spatial features from multi-source sensor data, employs the BiLSTM to capture temporal dependencies inherent to the crystal growth process, and utilizes the self-attention mechanism to dynamically highlight critical feature information, thereby substantially enhancing the model’s capacity to represent complex industrial operating conditions. Experiments on operational production data collected from an industrial Czochralski (Cz) furnace, model TDR-180, demonstrate improved prediction accuracy and robustness over mechanism-based and single data-driven baselines, supporting practical process control and production optimization. Full article

Grain security is a fundamental guarantee for social stability and sustainable development. Accurate monitoring and prediction of overall granary temperature are essential for reducing storage losses and improving warehouse management efficiency. As an integrated system, the temperature evolution of the grain pile is deeply affected by its inherent physical structure and heat transfer pathways. Therefore, a multi-level warehouse–surface–line–point (WSLP) structural modeling approach driven by the physical properties of the grain pile is proposed to extract the joint environmental and spatial characteristics. Building upon the WSLP framework, a dual-channel time-series prediction architecture integrating both long short-term memory (LSTM) and iTransformer through a mutual verification fusion mechanism is developed to enable synchronized temperature forecasting across different regions of the grain piles. Experiments are conducted using real granary data from Shandong, China. The results demonstrate that the proposed model achieves more than 30% improvement over baseline methods in terms of MAE and RMSE. Moreover, the WSLP-LSTM–iTransformer framework significantly improves prediction accuracy in complex warehouse environments and enhances the interpretability and applicability of deep learning models for grain condition forecasting by incorporating real environmental characteristics. Full article

Marine oil spill detection using Synthetic Aperture Radar (SAR) is crucial but challenged by dynamic marine conditions, diverse spill scales, and limitations in existing algorithms regarding model size and real-time performance. To address these challenges, we propose LSFE-YOLO, a YOLOv8s-optimized (You Only Look Once version 8) lightweight model with an original, domain-tailored synergistic integration of FasterNet, GN-LSC Head (GroupNorm Lightweight Shared Convolution Head), and C2f_MBE (C2f Mobile Bottleneck Enhanced). FasterNet serves as the backbone (25% neck width reduction), leveraging partial convolution (PConv) to minimize memory access and redundant computations—overcoming traditional lightweight backbones’ high memory overhead—laying the foundation for real-time deployment while preserving feature extraction. The proposed GN-LSC Head replaces YOLOv8’s decoupled head: its shared convolutions reduce parameter redundancy by approximately 40%, and GroupNorm (Group Normalization) ensures stable accuracy under edge computing’s small-batch constraints, outperforming BatchNorm (Batch Normalization) in resource-limited scenarios. The C2f_MBE module integrates EffectiveSE (Effective Squeeze and Excitation)-optimized MBConv (Mobile Inverted Bottleneck Convolution) into C2f: MBConv’s inverted-residual design enhances multi-scale feature capture, while lightweight EffectiveSE strengthens discriminative oil spill features without extra computation, addressing the original C2f’s scale variability insufficiency. Additionally, an SE (Squeeze and Excitation) attention mechanism embedded upstream of SPPF (Spatial Pyramid Pooling Fast) suppresses background interference (e.g., waves, biological oil films), synergizing with FasterNet and C2f_MBE to form a cascaded feature optimization pipeline that refines representations throughout the model. Experimental results show that LSFE-YOLO improves mAP (mean Average Precision) by 1.3% and F1 score by 1.7% over YOLOv8s, while achieving substantial reductions in model size (81.9%), parameter count (82.9%), and computational cost (84.2%), alongside a 20 FPS (Frames Per Second) increase in detection speed. LSFE-YOLO offers an efficient and effective solution for real-time marine oil spill detection. Full article

The accurate prediction of human movement direction plays a crucial role in fields such as rehabilitation monitoring, sports science, and intelligent military systems. Based on plantar pressure and inertial sensor data, this study developed a hybrid deep learning model integrating a Convolutional Neural Network (CNN) and a Bidirectional Long Short-Term Memory (BiLSTM) network to enable joint spatiotemporal feature learning. Systematic comparative experiments involving four distinct deep learning models—CNN, BiLSTM, CNN-LSTM, and CNN-BiLSTM—were conducted to evaluate their convergence performance and prediction accuracy comprehensively. Results show that the CNN-BiLSTM model outperforms the other three models, achieving the lowest RMSE (0.26) and MAE (0.14) on the test set, with an R² of 0.86, which indicates superior fitting accuracy and generalization ability. The superior performance of the CNN-BiLSTM model is attributed to its ability to effectively capture local spatial features via CNN and model bidirectional temporal dependencies via BiLSTM, thus demonstrating strong adaptability for complex motion scenarios. This work focuses on the optimization and comparison of deep learning algorithms for spatiotemporal feature extraction, providing a reliable framework for real-time human motion prediction and offering potential applications in intelligent gait analysis, wearable monitoring, and adaptive human–machine interaction. Full article

Vista landscapes of historic cities embody unique spatial order and cultural memory, and the scientific quantification of their visual quality presents a common challenge for both heritage conservation and urban renewal. Focusing on the Beijing Central Axis, this study integrates VR panoramic technology with the SBE-SD evaluation method to develop a visual quality assessment framework suitable for vista landscapes of historic cities, systematically evaluating sectional differences in scenic beauty and identifying their key influencing factors. Thirteen typical viewing places and 17 assessment points were selected, and panoramic images were captured at each point. The evaluation framework comprising 3 first-level factors, 11 secondary factors, and 24 third-level factors was established, and a corresponding scoring table was designed through which students from related disciplines were recruited to conduct the evaluation. After obtaining valid data, scenic beauty values and landscape factor scores were analyzed, followed by correlation tests and backward stepwise regression. The results show the following: (1) The scenic beauty of the vista landscapes along the Central Axis shows sectional differentiation, with the middle section achieving the highest scenic beauty value, followed by the northern section, with the southern section scoring the lowest; specifically, Wanchunting Pavilion South scored the highest, while Tianqiao Bridge scored the lowest. (2) In terms of landscape factor scores, within spatial form, color scored the highest, followed by texture and scale, with volume scoring the lowest; within marginal profile, integrity scored higher than visual dominance; within visual structure, visual organization scored the highest, followed by visual patches, with visual hierarchy scoring the lowest. (3) Regression analysis identified six key influencing factors, ranked in descending order of significance as follows: color coordination degree of traditional buildings, spatial openness, spatial symmetry, hierarchy sense of buildings, texture regularity of traditional buildings, and visual dominance of historical landmark buildings. This study establishes a quantitative assessment pathway that connects subjective perception and objective environment with a replicable process, providing methodological support for the refined conservation and optimization of vista landscapes in historic cities while demonstrating the application potential of VR panoramic technology in urban landscape evaluation. Full article