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14 pages, 2579 KiB  
Article
Prediction of Subcutaneous Fat Thickness (SFT) in Pantaneiro Lambs: A Model Based on Adipometer and Body Measurements for Android Application
by Adrielly Lais Alves da Silva, Marcus Vinicius Porto dos Santos, Marcelo Corrêa da Silva, Hélio Almeida Ricardo, Marcio Rodrigues de Souza, Núbia Michelle Vieira da Silva and Fernando Miranda de Vargas Junior
AgriEngineering 2025, 7(8), 251; https://doi.org/10.3390/agriengineering7080251 - 7 Aug 2025
Abstract
The increasing adoption of digital technologies in the agriculture sector has significantly contributed to optimizing on-farm routines, especially in data-driven decision-making. This study aimed to develop an application to determine the slaughter point of lambs by predicting subcutaneous fat thickness (SFT) using pre-slaughter [...] Read more.
The increasing adoption of digital technologies in the agriculture sector has significantly contributed to optimizing on-farm routines, especially in data-driven decision-making. This study aimed to develop an application to determine the slaughter point of lambs by predicting subcutaneous fat thickness (SFT) using pre-slaughter parameters such as body weight (BW), body condition score (BCS), and skinfold measurements at the brisket (BST), lumbar (LST), and tail base (TST), obtained using an adipometer. A total of 45 Pantaneiros lambs were evaluated, finished in feedlot, and slaughtered at different body weights. Each pre-slaughter weight class showed a distinct carcass pattern when all parameters were included in the model. Exploratory analysis revealed statistical significance for all variables (p < 0.001). BW and LST were selected to construct the predictive equation (R2 = 55.44%). The regression equations were integrated into the developed application, allowing for in-field estimation of SFT based on simple measurements. Compared to conventional techniques such as ultrasound or visual scoring, this tool offers advantages in portability, objectivity, and immediate decision-making support. In conclusion, combining accessible technologies (e.g., adipometer) with traditional variables (e.g., body weight), represents an effective alternative for production systems aimed at optimizing and enhancing the value of lamb carcasses. Full article
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11 pages, 464 KiB  
Article
The Use of Self-Sampling Devices via a Smartphone Application to Encourage Participation in Cervical Cancer Screening: A Pilot Study
by Francesco Plotti, Fernando Ficarola, Giuseppina Fais, Carlo De Cicco Nardone, Roberto Montera, Daniela Luvero, Gianna Barbara Cundari, Alice Avian, Elisabetta Riva, Santina Castriciano, Silvia Angeletti, Massimo Ciccozzi, Roberto Angioli and Corrado Terranova
J. Clin. Med. 2025, 14(15), 5569; https://doi.org/10.3390/jcm14155569 - 7 Aug 2025
Abstract
Background: Cervical cancer ranks among the most prevalent tumors in low-income countries, with the Pap test as one of the primary screening tools. The Pap smear detects abnormal cells, the CLART test identifies specific HPV genotypes, and HPV self-sampling allows for self-collected HPV [...] Read more.
Background: Cervical cancer ranks among the most prevalent tumors in low-income countries, with the Pap test as one of the primary screening tools. The Pap smear detects abnormal cells, the CLART test identifies specific HPV genotypes, and HPV self-sampling allows for self-collected HPV testing. This study aimed to evaluate the feasibility of the first smartphone-based health device for home-collection HPV testing. Methods: Enrolled patients during the gynecological examination underwent three different samplings: Pap smear, HPV DNA genotyping test CLART, and vaginal HPV-Selfy swab. Each patient received a kit including an activation code, vaginal swab, and instructions. After performing the self-sample, patients returned the kit to our laboratory. Both the samples collected by the gynecologist and those collected by the patients themselves were analyzed. Results: A total of 277 patients were enrolled, with 226 self-collected swabs received for analysis. The assay yielded valid results for both self-collected and clinician-collected swabs in 190 patients. When comparing these results with paired clinician-taken vaginal swabs, we observed an agreement of 95.2% (Cohen’s Kappa: 0.845). We report an agreement of 93.7% (Cohen’s Kappa: 0.798). Conclusions: The study demonstrated the feasibility of HPV-Selfy as a complementary tool in cervical cancer screening, especially where adherence to traditional surveillance is low. Full article
(This article belongs to the Special Issue Recent Advances in Gynecological Cancer)
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22 pages, 728 KiB  
Article
Multi-Layered Security Assessment in mHealth Environments: Case Study on Server, Mobile and Wearable Components in the PHGL-COVID Platform
by Edi Marian Timofte, Mihai Dimian, Serghei Mangul, Alin Dan Potorac, Ovidiu Gherman, Doru Balan and Marcel Pușcașu
Appl. Sci. 2025, 15(15), 8721; https://doi.org/10.3390/app15158721 - 7 Aug 2025
Abstract
The growing use of mobile health (mHealth) technologies adds complexity and risk to the healthcare environment. This paper presents a multi-layered cybersecurity assessment of an in-house mHealth platform (PHGL-COVID), comprising a Docker-based server infrastructure, a Samsung Galaxy A55 smartphone, and a Galaxy Watch [...] Read more.
The growing use of mobile health (mHealth) technologies adds complexity and risk to the healthcare environment. This paper presents a multi-layered cybersecurity assessment of an in-house mHealth platform (PHGL-COVID), comprising a Docker-based server infrastructure, a Samsung Galaxy A55 smartphone, and a Galaxy Watch 7 wearable. The objective was to identify vulnerabilities across the server, mobile, and wearable components by emulating real-world attacks and conducting systematic penetration tests on each layer. Tools and methods specifically tailored to each technology were applied, revealing exploitable configurations, insecure Bluetooth Low Energy (BLE) communications, and exposure of Personal Health Records (PHRs). Key findings included incomplete container isolation, BLE metadata leakage, and persistent abuse of Android privacy permissions. This work delivers both a set of actionable recommendations for developers and system architects to strengthen the security of mHealth platforms, and a reproducible audit methodology that has been validated in a real-world deployment, effectively bridging the gap between theoretical threat models and practical cybersecurity practices in healthcare systems. Full article
(This article belongs to the Special Issue Advances in Cyber Security)
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20 pages, 1119 KiB  
Article
Smartphone-Assisted Experimentation as a Medium of Understanding Human Biology Through Inquiry-Based Learning
by Giovanna Brita Campilongo, Giovanna Tonzar-Santos, Maria Eduarda dos Santos Verginio and Camilo Lellis-Santos
Educ. Sci. 2025, 15(8), 1005; https://doi.org/10.3390/educsci15081005 - 6 Aug 2025
Abstract
The integration of Inquiry-Based Learning (IBL) and mobile technologies can transform science education, offering experimentation opportunities to students from budget-constrained schools. This study investigates the efficacy of smartphone-assisted experimentation (SAE) within IBL to enhance pre-service science teachers’ understanding of human physiology and presents [...] Read more.
The integration of Inquiry-Based Learning (IBL) and mobile technologies can transform science education, offering experimentation opportunities to students from budget-constrained schools. This study investigates the efficacy of smartphone-assisted experimentation (SAE) within IBL to enhance pre-service science teachers’ understanding of human physiology and presents a newly developed and validated rubric for assessing their scientific skills. Students (N = 286) from a Science and Mathematics Teacher Education Program participated in a summative IBL activity (“Investigating the Human Physiology”—iHPhys) where they designed experimental projects using smartphone applications to collect body sign data. The scoring rubric, assessing seven criteria including hypothesis formulation, methodological design, data presentation, and conclusion writing, was validated as substantial to almost perfect inter-rater reliability. Results reveal that students exhibited strong skills in hypothesis clarity, theoretical grounding, and experimental design, with a high degree of methodological innovation observed. However, challenges persisted in predictive reasoning and evidence-based conclusion writing. The students were strongly interested in inquiring about the cardiovascular and nervous systems. Correlational analyses suggest a positive relationship between project originality and overall academic performance. Thus, integrating SAE and IBL fosters critical scientific competencies, creativity, and epistemic cognition while democratizing access to scientific experimentation and engaging students in tech-savvy pedagogical practices. Full article
(This article belongs to the Special Issue Inquiry-Based Learning and Student Engagement)
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16 pages, 5519 KiB  
Article
The Performance of a Novel Automated Algorithm in Estimating Truckload Volume Based on LiDAR Data
by Mihai Daniel Niţă, Cătălin Cucu-Dumitrescu, Bogdan Candrea, Bogdan Grama, Iulian Iuga and Stelian Alexandru Borz
Forests 2025, 16(8), 1281; https://doi.org/10.3390/f16081281 - 5 Aug 2025
Abstract
Significant improvements in the forest-based industrial sector are expected due to increased digitalization; however, examples of practical implementations remain limited. This study explores the use of an automated algorithm to estimate truckload volumes based on 3D point cloud data acquired using two different [...] Read more.
Significant improvements in the forest-based industrial sector are expected due to increased digitalization; however, examples of practical implementations remain limited. This study explores the use of an automated algorithm to estimate truckload volumes based on 3D point cloud data acquired using two different LiDAR scanning platforms. This research compares the performance of a professional mobile laser scanning (MLS GeoSLAM) platform and a smartphone-based iPhone LiDAR system. A total of 48 truckloads were measured using a combination of manual, factory-based, and digital approaches. Accuracy was evaluated using standard error metrics, including the mean absolute error (MAE) and root mean square error (RMSE), with manual or factory references used as benchmarks. The results showed a strong correlation and no significant differences between the algorithmic and manual measurements when using the MLS platform (MAE = 2.06 m3; RMSE = 2.46 m3). For the iPhone platform, the results showed higher deviations and significant overestimation compared to the factory reference (MAE = 3.29 m3; RMSE = 3.60 m3). Despite these differences, the iPhone platform offers real-time acquisition and low-cost deployment. These findings highlight the trade-offs between precision and operational efficiency and support the adoption of automated measurement tools in timber supply chains. Full article
(This article belongs to the Section Forest Operations and Engineering)
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18 pages, 2879 KiB  
Article
Smartphone-Compatible Colorimetric Detection of CA19-9 Using Melanin Nanoparticles and Deep Learning
by Turgut Karademir, Gizem Kaleli-Can and Başak Esin Köktürk-Güzel
Biosensors 2025, 15(8), 507; https://doi.org/10.3390/bios15080507 - 5 Aug 2025
Abstract
Paper-based colorimetric biosensors represent a promising class of low-cost diagnostic tools that do not require external instrumentation. However, their broader applicability is limited by the environmental concerns associated with conventional metal-based nanomaterials and the subjectivity of visual interpretation. To address these challenges, this [...] Read more.
Paper-based colorimetric biosensors represent a promising class of low-cost diagnostic tools that do not require external instrumentation. However, their broader applicability is limited by the environmental concerns associated with conventional metal-based nanomaterials and the subjectivity of visual interpretation. To address these challenges, this study introduces a proof-of-concept platform—using CA19-9 as a model biomarker—that integrates naturally derived melanin nanoparticles (MNPs) with machine learning-based image analysis to enable environmentally sustainable and analytically robust colorimetric quantification. Upon target binding, MNPs induce a concentration-dependent color transition from yellow to brown. This visual signal was quantified using a machine learning pipeline incorporating automated region segmentation and regression modeling. Sensor areas were segmented using three different algorithms, with the U-Net model achieving the highest accuracy (average IoU: 0.9025 ± 0.0392). Features extracted from segmented regions were used to train seven regression models, among which XGBoost performed best, yielding a Mean Absolute Percentage Error (MAPE) of 17%. Although reduced sensitivity was observed at higher analyte concentrations due to sensor saturation, the model showed strong predictive accuracy at lower concentrations, which are especially challenging for visual interpretation. This approach enables accurate, reproducible, and objective quantification of colorimetric signals, thereby offering a sustainable and scalable alternative for point-of-care diagnostic applications. Full article
(This article belongs to the Special Issue AI-Enabled Biosensor Technologies for Boosting Medical Applications)
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14 pages, 2198 KiB  
Article
A Portable and Thermally Degradable Hydrogel Sensor Based on Eu-Doped Carbon Dots for Visual and Ultrasensitive Detection of Ferric Ion
by Hongyuan Zhang, Qian Zhang, Juan Tang, Huanxin Yang, Xiaona Ji, Jieqiong Wang and Ce Han
Molecules 2025, 30(15), 3280; https://doi.org/10.3390/molecules30153280 - 5 Aug 2025
Abstract
Degradable fluorescent sensors present a promising portable approach for heavy metal ion detection, aiming to prevent secondary environmental pollution. Additionally, the excessive intake of ferric ions (Fe3+), an essential trace element for human health, poses critical health risks that urgently require [...] Read more.
Degradable fluorescent sensors present a promising portable approach for heavy metal ion detection, aiming to prevent secondary environmental pollution. Additionally, the excessive intake of ferric ions (Fe3+), an essential trace element for human health, poses critical health risks that urgently require effective monitoring. In this study, we developed a thermally degradable fluorescent hydrogel sensor (Eu-CDs@DPPG) based on europium-doped carbon dots (Eu-CDs). The Eu-CDs, synthesized via a hydrothermal method, exhibited selective fluorescence quenching by Fe3+ through the inner filter effect (IFE). Embedding Eu-CDs into the hydrogel significantly enhanced their stability and dispersibility in aqueous environments, effectively resolving issues related to aggregation and matrix interference in traditional sensing methods. The developed sensor demonstrated a broad linear detection range (0–2.5 µM), an extremely low detection limit (1.25 nM), and rapid response (<40 s). Furthermore, a smartphone-assisted LAB color analysis allowed portable, visual quantification of Fe3+ with a practical LOD of 6.588 nM. Importantly, the hydrogel was thermally degradable at 80 °C, thus minimizing environmental impact. The sensor’s practical applicability was validated by accurately detecting Fe3+ in spinach and human urine samples, achieving recoveries of 98.7–108.0% with low relative standard deviations. This work provides an efficient, portable, and sustainable sensing platform that overcomes the limitations inherent in conventional analytical methods. Full article
(This article belongs to the Section Photochemistry)
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18 pages, 1582 KiB  
Article
Design of an ASIC Vector Engine for a RISC-V Architecture
by Miguel Bucio-Macías, Luis Pizano-Escalante and Omar Longoria-Gandara
Chips 2025, 4(3), 33; https://doi.org/10.3390/chips4030033 - 5 Aug 2025
Abstract
Nowadays, Graphical Processor Units (GPUs) are a great technology to implement Artificial Intelligence (AI) processes; however, a challenge arises when the inclusion of a GPU is not feasible due to the cost, power consumption, or the size of the hardware. This issue is [...] Read more.
Nowadays, Graphical Processor Units (GPUs) are a great technology to implement Artificial Intelligence (AI) processes; however, a challenge arises when the inclusion of a GPU is not feasible due to the cost, power consumption, or the size of the hardware. This issue is particularly relevant for portable devices, such as laptops or smartphones, where the inclusion of a dedicated GPU is not the best option. One possible solution to that problem is the use of a CPU with AI capabilities, i.e., parallelism and high performance. In particular, RISC-V architecture is considered a good open-source candidate to support such tasks. These capabilities are based on vector operations that, by definition, operate over many elements at the same time, allowing for the execution of SIMD instructions that can be used to implement typical AI routines and procedures. In this context, the main purpose of this proposal is to develop an ASIC Vector Engine RISC-V architecture compliant that implements a minimum set of the Vector Extension capable of the parallel processing of multiple data elements with a single instruction. These instructions operate on vectors and involve addition, multiplication, logical, comparison, and permutation operations. Especially, the multiplication was implemented using the Vedic multiplication algorithm. Contributions include the description of the design, synthesis, and validation processes to develop the ASIC, and a performance comparison between the FPGA implementation and the ASIC using different nanometric technologies, where the best performance of 110 MHz, and the best implementation in terms of silicon area, was achieved by 7 nm technology. Full article
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13 pages, 2224 KiB  
Article
Digital Eye Strain Monitoring for One-Hour Smartphone Engagement Through Eye Activity Measurement System
by Bhanu Priya Dandumahanti, Prithvi Krishna Chittoor and Murali Subramaniyam
J. Eye Mov. Res. 2025, 18(4), 34; https://doi.org/10.3390/jemr18040034 - 5 Aug 2025
Viewed by 2
Abstract
Smartphones have revolutionized our daily lives, becoming portable pocket computers with easy internet access. India, the second-highest smartphone and internet user, experienced a significant rise in smartphone usage between 2013 and 2024. Prolonged smartphone use, exceeding 20 min at a time, can lead [...] Read more.
Smartphones have revolutionized our daily lives, becoming portable pocket computers with easy internet access. India, the second-highest smartphone and internet user, experienced a significant rise in smartphone usage between 2013 and 2024. Prolonged smartphone use, exceeding 20 min at a time, can lead to physical and mental health issues, including psychophysiological disorders. Digital devices and their extended exposure to blue light cause digital eyestrain, sleep disorders and visual-related problems. This research examines the impact of 1 h smartphone usage on visual fatigue among young Indian adults. A portable, low-cost system has been developed to measure visual activity to address this. The developed visual activity measurement system measures blink rate, inter-blink interval, and pupil diameter. Measured eye activity was recorded during 1 h smartphone usage of e-book reading, video watching, and social-media reels (short videos). Social media reels show increased screen variations, affecting pupil dilation and reducing blink rate due to continuous screen brightness and intensity changes. This reduction in blink rate and increase in inter-blink interval or pupil dilation could lead to visual fatigue. Full article
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15 pages, 5856 KiB  
Article
Smart Personal Protective Equipment Hood Based on Dedicated Communication Protocol
by Mario Gazziro, Marcio Luís Munhoz Amorim, Marco Roberto Cavallari, João Paulo Carmo and Oswaldo Hideo Ando Júnior
Hardware 2025, 3(3), 8; https://doi.org/10.3390/hardware3030008 - 5 Aug 2025
Viewed by 73
Abstract
This project aimed to develop personal protective equipment (PPE) that provides full biological protection for the general public without the need for extensive training to use the equipment. With the proposal to develop a device guided by a smartphone monitoring application (to guide [...] Read more.
This project aimed to develop personal protective equipment (PPE) that provides full biological protection for the general public without the need for extensive training to use the equipment. With the proposal to develop a device guided by a smartphone monitoring application (to guide the user on the replacement of perishable components, ensuring their safety and biological protection in potentially contaminated places), the embedded electronics of this equipment were built, as well as their control system, including a smartphone app. Thus, a device was successfully developed to monitor and assist individuals in using an advanced PPE device. Full article
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13 pages, 1060 KiB  
Article
Condition Changes Before and After the Coronavirus Disease 2019 Pandemic in Adolescent Athletes and Development of a Non-Contact Medical Checkup Application
by Hiroaki Kijima, Toyohito Segawa, Kimio Saito, Hiroaki Tsukamoto, Ryota Kimura, Kana Sasaki, Shohei Murata, Kenta Tominaga, Yo Morishita, Yasuhito Asaka, Hidetomo Saito and Naohisa Miyakoshi
Sports 2025, 13(8), 256; https://doi.org/10.3390/sports13080256 - 4 Aug 2025
Viewed by 162
Abstract
During the coronavirus 2019 pandemic, sports activities were restricted, raising concerns about their impact on the physical condition of adolescent athletes, which remained largely unquantified. This study was designed with two primary objectives: first, to precisely quantify and elucidate the differences in the [...] Read more.
During the coronavirus 2019 pandemic, sports activities were restricted, raising concerns about their impact on the physical condition of adolescent athletes, which remained largely unquantified. This study was designed with two primary objectives: first, to precisely quantify and elucidate the differences in the physical condition of adolescent athletes before and after activity restrictions due to the pandemic; and second, to innovatively develop and validate a non-contact medical checkup application. Medical checks were conducted on 563 athletes designated for sports enhancement. Participants were junior high school students aged 13 to 15, and the sample consisted of 315 boys and 248 girls. Furthermore, we developed a smartphone application and compared self-checks using the application with in-person checks by orthopedic surgeons to determine the challenges associated with self-checks. Statistical tests were conducted to determine whether there were statistically significant differences in range of motion and flexibility parameters before and after the pandemic. Additionally, items with discrepancies between values self-entered by athletes using the smartphone application and values measured by specialists were detected, and application updates were performed. Student’s t-test was used for continuous variables, whereas the chi-square test was used for other variables. Following the coronavirus 2019 pandemic, athletes were stiffer than during the pre-pandemic period in terms of hip and shoulder joint rotation range of motion and heel–buttock distance. The dominant hip external rotation decreased from 53.8° to 46.8° (p = 0.0062); the non-dominant hip external rotation decreased from 53.5° to 48.0° (p = 0.0252); the dominant shoulder internal rotation decreased from 62.5° to 54.7° (p = 0.0042); external rotation decreased from 97.6° to 93.5° (p = 0.0282), and the heel–buttock distance increased from 4.0 cm to 10.4 cm (p < 0.0001). The heel–buttock distance and straight leg raising angle measurements differed between the self-check and face-to-face check. Although there are items that cannot be accurately evaluated by self-check, physical condition can be improved with less contact by first conducting a face-to-face evaluation under appropriate guidance and then conducting a self-check. These findings successfully address our primary objectives. Specifically, we demonstrated a significant decline in the physical condition of adolescent athletes following pandemic-related activity restrictions, thereby quantifying their impact. Furthermore, our developed non-contact medical checkup application proved to be a viable tool for monitoring physical condition with reduced contact, although careful consideration of measurable parameters is crucial. This study provides critical insights into the long-term effects of activity restrictions on young athletes and offers a practical solution for health monitoring during infectious disease outbreaks, highlighting the potential for hybrid checkup approaches. Full article
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21 pages, 1147 KiB  
Review
Recent Advances in Developing Cell-Free Protein Synthesis Biosensors for Medical Diagnostics and Environmental Monitoring
by Tyler P. Green, Joseph P. Talley and Bradley C. Bundy
Biosensors 2025, 15(8), 499; https://doi.org/10.3390/bios15080499 - 3 Aug 2025
Viewed by 234
Abstract
Cell-free biosensors harness the selectivity of cellular machinery without living cells’ constraints, offering advantages in environmental monitoring, medical diagnostics, and biotechnological applications. This review examines recent advances in cell-free biosensor development, highlighting their ability to detect diverse analytes including heavy metals, organic pollutants, [...] Read more.
Cell-free biosensors harness the selectivity of cellular machinery without living cells’ constraints, offering advantages in environmental monitoring, medical diagnostics, and biotechnological applications. This review examines recent advances in cell-free biosensor development, highlighting their ability to detect diverse analytes including heavy metals, organic pollutants, pathogens, and clinical biomarkers with high sensitivity and specificity. We analyze technological innovations in cell-free protein synthesis optimization, preservation strategies, and field deployment methods that have enhanced sensitivity, and practical applicability. The integration of synthetic biology approaches has enabled complex signal processing, multiplexed detection, and novel sensor designs including riboswitches, split reporter systems, and metabolic sensing modules. Emerging materials such as supported lipid bilayers, hydrogels, and artificial cells are expanding biosensor capabilities through microcompartmentalization and electronic integration. Despite significant progress, challenges remain in standardization, sample interference mitigation, and cost reduction. Future opportunities include smartphone integration, enhanced preservation methods, and hybrid sensing platforms. Cell-free biosensors hold particular promise for point-of-care diagnostics in resource-limited settings, environmental monitoring applications, and food safety testing, representing essential tools for addressing global challenges in healthcare, environmental protection, and biosecurity. Full article
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16 pages, 1053 KiB  
Article
The Relationship Between Parental Phubbing and Preschoolers’ Behavioral Problems: The Mediation Role of Mindful Attention Awareness
by Antonio Puligheddu, Annamaria Porru, Andrea Spano, Stefania Cataudella, Maria Lidia Mascia, Dolores Rollo, Cristina Cabras, Maria Pietronilla Penna and Daniela Lucangeli
Children 2025, 12(8), 1022; https://doi.org/10.3390/children12081022 - 2 Aug 2025
Viewed by 517
Abstract
Phubbing, a relatively new phenomenon in the field of digital risks, refers to the act of ignoring someone in favor of focusing on a smartphone during face-to-face interactions. Parental phubbing, a specific form of this behavior, is a prevalent negative parenting practice that [...] Read more.
Phubbing, a relatively new phenomenon in the field of digital risks, refers to the act of ignoring someone in favor of focusing on a smartphone during face-to-face interactions. Parental phubbing, a specific form of this behavior, is a prevalent negative parenting practice that can affect parent–child relationships and child development. However, the impact of parental phubbing on the emotional and behavioral development of preschool children remains unclear. This study aims to explore the relationship between parental phubbing and preschoolers’ behavioral problems, as well as test whether parents’ mindful attention awareness (MAA) acts as a mediator between them. Method: A questionnaire was administered to 138 Italian parents (mean age = 38.5, SD = 6.2) of 138 kindergarten preschoolers (mean age = 3.9, SD = 1.03). Questionnaires included the Generic Scale of Phubbing (GSP), the Mindful Attention Awareness Scale (MAAS), and the Strengths and Difficulties Questionnaire (SDQ). Results: Analyses revealed a significant negative correlation between the MAAS and SDQ total scores, a positive correlation between the GSP total score and the SDQ total score, and a negative correlation between the GSP total score and the MAAS total score. The mediation analysis did not show a direct effect of GSP on SDQ, suggesting that parental phubbing did not directly predict children’s behavioral difficulties. Nevertheless, the indirect effect measured by bootstrapping was significant, indicating that parental MAA fully mediated the relationship between parental phubbing and preschoolers’ problematic behaviors. Conclusions: Although further research is needed, parental mindfulness may influence phubbing behaviors in parents providing valuable insights for early interventions aimed at reducing problem behaviors in young children. Full article
(This article belongs to the Section Pediatric Mental Health)
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21 pages, 2240 KiB  
Review
A Review of Fluorescent pH Probes: Ratiometric Strategies, Extreme pH Sensing, and Multifunctional Utility
by Weiqiao Xu, Zhenting Ma, Qixin Tian, Yuanqing Chen, Qiumei Jiang and Liang Fan
Chemosensors 2025, 13(8), 280; https://doi.org/10.3390/chemosensors13080280 - 2 Aug 2025
Viewed by 233
Abstract
pH is a critical parameter requiring precise monitoring across scientific, industrial, and biological domains. Fluorescent pH probes offer a powerful alternative to traditional methods (e.g., electrodes, indicators), overcoming limitations in miniaturization, long-term stability, and electromagnetic interference. By utilizing photophysical mechanisms—including intramolecular charge transfer [...] Read more.
pH is a critical parameter requiring precise monitoring across scientific, industrial, and biological domains. Fluorescent pH probes offer a powerful alternative to traditional methods (e.g., electrodes, indicators), overcoming limitations in miniaturization, long-term stability, and electromagnetic interference. By utilizing photophysical mechanisms—including intramolecular charge transfer (ICT), photoinduced electron transfer (PET), and fluorescence resonance energy transfer (FRET)—these probes enable high-sensitivity, reusable, and biocompatible sensing. This review systematically details recent advances, categorizing probes by operational pH range: strongly acidic (0–3), weakly acidic (3–7), strongly alkaline (>12), weakly alkaline (7–11), near-neutral (6–8), and wide-dynamic range. Innovations such as ratiometric detection, organelle-specific targeting (lysosomes, mitochondria), smartphone colorimetry, and dual-analyte response (e.g., pH + Al3+/CN) are highlighted. Applications span real-time cellular imaging (HeLa cells, zebrafish, mice), food quality assessment, environmental monitoring, and industrial diagnostics (e.g., concrete pH). Persistent challenges include extreme-pH sensing (notably alkalinity), photobleaching, dye leakage, and environmental resilience. Future research should prioritize broadening functional pH ranges, enhancing probe stability, and developing wide-range sensing strategies to advance deployment in commercial and industrial online monitoring platforms. Full article
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22 pages, 505 KiB  
Article
When Interaction Becomes Addiction: The Psychological Consequences of Instagram Dependency
by Blanca Herrero-Báguena, Silvia Sanz-Blas and Daniela Buzova
J. Theor. Appl. Electron. Commer. Res. 2025, 20(3), 195; https://doi.org/10.3390/jtaer20030195 - 2 Aug 2025
Viewed by 306
Abstract
The purpose of the present research is to analyse the negative outcomes associated with the excessive Instagram dependency of those users that access the application through their smartphones. An empirical study was conducted through online interviews using structured questionnaires, resulting in 342 valid [...] Read more.
The purpose of the present research is to analyse the negative outcomes associated with the excessive Instagram dependency of those users that access the application through their smartphones. An empirical study was conducted through online interviews using structured questionnaires, resulting in 342 valid responses, with the target population being young users over 18 years old who access Instagram daily. Research shows that dependency on Instagram is primarily driven by individuals’ need for orientation and understanding, with entertainment being a secondary motivation. The results indicate that dependency on the social network is positively associated with excessive use, addiction, and Instastress. Furthermore, excessive use contributes to personal and social problems and increases both stress levels and mindfulness related to the platform. In turn, this excessive use intensifies addiction, which functions as a mediating variable between overuse and Instastress, mindfulness, and emotional exhaustion. This study offers valuable insights for academics, mental health professionals, and marketers by emphasizing the importance of fostering healthier digital habits and developing targeted interventions. Full article
(This article belongs to the Topic Interactive Marketing in the Digital Era)
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