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Impact of Somatic DNA Repair Mutations on the Clinical Outcomes of Bone Metastases from Castration-Resistant Prostate Cancer
- Maria Concetta Cursano,
- Emilio Francesco Giunta,
- Emanuela Scarpi,
- Chiara Casadei,
- Alessandra Virga,
- Paola Ulivi,
- Sara Bleve,
- Nicole Brighi,
- Giorgia Ravaglia and
- Ugo De Giorgi
- + 3 authors
Up to 80% of castration-resistant prostate cancer (CRPC) patients develop bone metastases during the natural history of disease and about 25% harbor mutations in DNA damage repair (DDR) genes. This retrospective observational study evaluated the prev...