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Review

17 Citations

16,535 Views

19 Pages

Corticosteroid-Induced Psychiatric Disorders: Mechanisms, Outcomes, and Clinical Implications

Lara Nasereddin,
Omar Alnajjar,
Homam Bashar,
Sara Feras Abuarab,
Rahma Al-Adwan,
Dinesh Kumar Chellappan and
Muna Barakat

Diseases2024, 12(12), 300;https://doi.org/10.3390/diseases12120300

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23 November 2024

Corticosteroids are extensively used in medicine for their powerful anti-inflammatory and immunosuppressive effects. However, their psychiatric side effects—such as mood disturbances, anxiety, and psychosis—are significant yet often under...

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Review

9 Citations

6,785 Views

22 Pages

Recent Updates on Corticosteroid-Induced Neuropsychiatric Disorders and Theranostic Advancements through Gene Editing Tools

Manisha Singh,
Vinayak Agarwal,
Divya Jindal,
Pranav Pancham,
Shriya Agarwal,
Shalini Mani,
Raj Kumar Tiwari,
Koushik Das,
Badrah S. Alghamdi and
Saurabh Kumar Jha
+ 2 authors

Diagnostics2023, 13(3), 337;https://doi.org/10.3390/diagnostics13030337

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17 January 2023

The vast use of corticosteroids (CCSs) globally has led to an increase in CCS-induced neuropsychiatric disorders (NPDs), a very common manifestation in patients after CCS consumption. These neuropsychiatric disorders range from depression, insomnia,...

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Review

2 Citations

3,869 Views

12 Pages

Immune Effector Cell-Associated Neurotoxicity Syndrome After CAR T-Cell Therapy and Other Psychiatric Manifestations: A Review and Case Series

Adela Georgiana Buciuc,
Sabrina Tran,
Mary Weber,
Vanessa Padilla,
Maria Rueda-Lara and
Zelde Espinel

J. Clin. Med.2025, 14(5), 1451;https://doi.org/10.3390/jcm14051451

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21 February 2025

Background/Objectives: Chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment of hematologic malignancies, achieving durable remissions in cases refractory to standard therapies. A potentially life-threatening complication is im...

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