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Keywords = polymer-based dental materials

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24 pages, 23717 KB  
Article
Fracture Strength of CAD/CAM Endocrown and Post-Core Restorations with Fiber Strip Reinforcement in Mandibular Premolars
by Kerem Yılmaz, Hakan Aydın, Zeynep Soylu, Özge Çiloğlu, Esma Fatıma Delican, Mehmet Mustafa Özarslan and Fehmi Gönüldaş
J. Funct. Biomater. 2026, 17(5), 248; https://doi.org/10.3390/jfb17050248 - 17 May 2026
Viewed by 275
Abstract
This study evaluated the effects of restorative material, restoration type, and fiber strip reinforcement on the fracture strength (FS) of endocrown (EC) and post-core (PC) restorations in endodontically treated premolars. Specimens were allocated according to restorative material [resin-nanoceramic (RNC) or feldspathic ceramic (FC)], [...] Read more.
This study evaluated the effects of restorative material, restoration type, and fiber strip reinforcement on the fracture strength (FS) of endocrown (EC) and post-core (PC) restorations in endodontically treated premolars. Specimens were allocated according to restorative material [resin-nanoceramic (RNC) or feldspathic ceramic (FC)], restoration type (EC or PC), and reinforcement [fiber strip-reinforced (FR) or -non-reinforced (NF)]. FS was determined using a universal testing machine under axial loading. Statistical analysis was performed using three-way ANOVA and Bonferroni tests (α = 0.05). Material, restoration type, and reinforcement significantly affected FS (p < 0.05). RNC restorations exhibited higher FS than FC restorations (861 ± 181 N vs. 715 ± 212 N; p < 0.001). EC restorations exhibited higher FS than PC restorations (828 ± 173 N vs. 748 ± 236 N; p = 0.046). FR groups exhibited higher FS than NF groups (848 ± 180 N vs. 728 ± 222 N; p = 0.003). The highest FS was observed in the RNC–PC–FR group (965 ± 144 N), whereas the lowest occurred in the FC–PC–NF group (480 ± 177 N). Although EC restorations showed higher FS than PC restorations, the effect of restoration type depended on material and reinforcement. Full article
(This article belongs to the Section Dental Biomaterials)
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13 pages, 1404 KB  
Article
Effects of Ultrasonic Scaling and Teeth Brushing on Surface Properties of PEEK Prosthetic Restorations
by Aleksandra D. Čairović, Mirjana M. Perić, Nevena Čairović, Luka Župac, Vesna M. Maksimović, Sanja S. Stevanović, Aleksandra B. Špadijer-Gostović and Dragan M. Stanimirović
Dent. J. 2026, 14(5), 303; https://doi.org/10.3390/dj14050303 - 15 May 2026
Viewed by 159
Abstract
Purpose: This study provides a comparative evaluation of surface changes in BioHPP materials under routine professional hygiene procedures, which is recommended by dentists, twice a year. BioHPP is a polyetheretherketone polymer used in prosthetic dentistry as a frame material. The aim was to [...] Read more.
Purpose: This study provides a comparative evaluation of surface changes in BioHPP materials under routine professional hygiene procedures, which is recommended by dentists, twice a year. BioHPP is a polyetheretherketone polymer used in prosthetic dentistry as a frame material. The aim was to investigate whether routine dental cleaning procedures such as ultrasonic scaling and brushing affect the surface proprieties of prosthetic BioHPP restorations. This study was conducted to evaluate the surface properties of different restorations based on BioHPP (veneered with composite resin and polished) after brushing and ultrasonic scaling exposure. Materials and Methods: The BioHPP specimens were divided into three groups. The first group (marked BioHPP) served as a baseline reference for assessing the effect of different surface processing approaches, and no further treatment was applied. The specimens in the second group (BioHPP-P) were polished, while the specimens in the third group (BioHPP-C) were veneered with composite resin. Group BioHPP-P and BioHPP-C of samples was divided into three subgroups: 0—no treatment, 1—exposed to tooth brushing, 2—exposed to ultrasonic scaling. Untreated samples (subgroup 0) served as controls for evaluating treatment-related changes within groups 2 and 3. The surface morphology was investigated by atomic force microscopy (AFM). The structure of samples was analyzed using the XRD technique, and the surface wettability was evaluated. Results: The surface roughness of the samples was evaluated via root mean square (RMS) parameter. Baseline BioHPP specimens exhibited higher roughness values compared to the other analyzed groups. The roughness of the non-treated specimens (0) decreased in the line 59.18→28.84→14.51 nm. Treatment of the samples by brushing and ultrasonic scaling was associated with an increase in surface roughness. Variations in water contact angle values were observed. However, no consistent treatment-related trend could be established. Conclusions: Composite veneered BioHPP showed a tendency toward higher surface resistance to brushing and ultrasonic scaling. These findings should be interpreted within the limitations of an in vitro descriptive study. Full article
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20 pages, 2581 KB  
Review
Advanced Biomaterials for Restorative Dentistry: From Biocompatibility to Bioactive and Smart Materials
by Maria Claudia Albu, Corina Laura Ștefănescu, Rodica Maria Murineanu, Mircea Grigorian, Liliana Sachelarie, Agripina Zaharia, Loredana Liliana Hurjui and Aureliana Caraiane
Bioengineering 2026, 13(5), 542; https://doi.org/10.3390/bioengineering13050542 - 9 May 2026
Viewed by 823
Abstract
(1) Background: The development of advanced dental biomaterials has significantly improved restorative dentistry, shifting the focus from purely mechanical restoration toward materials capable of interacting biologically with oral tissues. Modern restorative materials are expected to demonstrate high biocompatibility, adequate mechanical properties, and potential [...] Read more.
(1) Background: The development of advanced dental biomaterials has significantly improved restorative dentistry, shifting the focus from purely mechanical restoration toward materials capable of interacting biologically with oral tissues. Modern restorative materials are expected to demonstrate high biocompatibility, adequate mechanical properties, and potential bioactivity that may support tissue preservation and long-term clinical performance. This review aims to analyze recent advances in next-generation dental restorative materials and to evaluate their biological compatibility and potential clinical relevance. (2) Methods: A narrative literature review was conducted using major scientific databases, including PubMed, Scopus, and Web of Science, focusing on studies addressing advanced polymer-based composites, bioactive restorative materials, dental ceramics, computer-aided design and computer-aided manufacturing (CAD–CAM) restorative systems, and nanostructured biomaterials used in restorative dentistry. Relevant studies published in recent years were analyzed with respect to material composition, biological response, and reported clinical performance. (3) Results: The reviewed literature indicates that modern dental biomaterials, including nanocomposites, bioactive glass-containing materials, calcium silicate–based systems, and hybrid ceramic materials, show improved mechanical stability, enhanced remineralization potential, and reduced bacterial adhesion compared with traditional restorative materials. Advances in nanotechnology and material engineering have also contributed to the development of antimicrobial and bioactive restorative systems. (4) Conclusions: Next-generation dental restorative materials demonstrate promising characteristics that may improve clinical outcomes and biological integration in restorative dentistry; however, further long-term clinical investigations are required to fully confirm their safety, durability, and long-term effectiveness. Full article
(This article belongs to the Special Issue Advanced Dental Materials for Restorative Dentistry)
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19 pages, 3808 KB  
Article
Advancing Guidelines for the Design of Tooth-Supported Surgical Guides with Free-End Configurations: A Simulation Study of the Influence of Surgeon’s Hand Force
by Nikola Šimunić, Vladimir Tudić, Josip Hoster and Zvonimir Kralj
Appl. Sci. 2026, 16(7), 3287; https://doi.org/10.3390/app16073287 - 28 Mar 2026
Viewed by 315
Abstract
Numerous studies have demonstrated that tooth-supported dental guides improve the accuracy of implant placement. However, current manufacturing procedures and available materials are not yet optimal and may still lead to deviations from the planned implant position. The influence of the surgeon’s manual force [...] Read more.
Numerous studies have demonstrated that tooth-supported dental guides improve the accuracy of implant placement. However, current manufacturing procedures and available materials are not yet optimal and may still lead to deviations from the planned implant position. The influence of the surgeon’s manual force on the deformation of dental guides during implant placement has not yet been sufficiently investigated. Therefore, this study evaluates the mechanical behavior of dental guides using finite element analysis (FEA) in order to assess the influence of the surgeon’s hand force during clinical application. Finite element simulations of deformation and stress were performed for four types of tooth-supported dental guides, including cantilever dental guides with free ends and beam-type guides with a large span between the supporting teeth. The manual force applied by the surgeon was arbitrarily set to 30 N. Simulations were conducted for five commonly used biocompatible polymer materials: Stratasys MED610, VeroGlaze MED620, EOS PA2200, Formlabs FLSGAM01, and Stratasys ULTEM 1010. The numerical results quantified the deformation of dental guides caused by the applied manual force during surgical manipulation. For all analyzed guide designs, the deflection was primarily influenced by the arm length, i.e., the distance between the support and the point of force application. Based on the obtained results, design diagrams were developed to provide guidelines for the design of beam-type (A and A1) and cantilever-type (B and B1) tooth-supported dental guides. Full article
(This article belongs to the Special Issue Dental Biomaterials and Implants: Latest Advances and Prospects)
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30 pages, 9485 KB  
Article
Morphological, Thermal, Mechanical and Cytotoxic Investigation of Hydroxyapatite Reinforced Chitosan/Collagen 3D Bioprinted Dental Grafts
by Ubeydullah Nuri Hamedi, Fatih Ciftci, Tülay Merve Soylu, Mine Kucak, Ali Can Özarslan and Sakir Altinsoy
Polymers 2026, 18(7), 816; https://doi.org/10.3390/polym18070816 - 27 Mar 2026
Viewed by 729
Abstract
Dental tissue regeneration, particularly alveolar bone and gingival repair, remains a major challenge in regenerative medicine. 3D bioprinting offers patient-specific and anatomically precise constructs, representing an advanced alternative to conventional grafting. In this study, nanohydroxyapatite (nHA), chitosan (CS), and collagen (CoL) were combined [...] Read more.
Dental tissue regeneration, particularly alveolar bone and gingival repair, remains a major challenge in regenerative medicine. 3D bioprinting offers patient-specific and anatomically precise constructs, representing an advanced alternative to conventional grafting. In this study, nanohydroxyapatite (nHA), chitosan (CS), and collagen (CoL) were combined to fabricate and characterize 3D bioprinted dental grafts. SEM revealed a highly porous, interconnected architecture favorable for cell infiltration and nutrient exchange. EDS confirmed Ca/P ratios of 2.06 for nHA/CoL and 1.83 for nHA/CS/CoL, both of which are above the stoichiometric 1.67, indicating the presence of additional mineral phases and ion substitutions. FTIR and XRD verified characteristic functional groups and crystalline phases, including B-type HA with carbonate substitution. Mechanical testing showed that pure nHA exhibited the lowest compressive strength, whereas CoL incorporation improved stiffness. The nHA/CS/CoL composite achieved the highest compressive strength, elastic modulus, and toughness, demonstrating superior mechanical resilience. DSC analysis indicated endothermic peaks at 106.49 °C and 351.91 °C, with enthalpy values (264.91 J/g and 15.09 J/g) surpassing those of nHA alone. TGA revealed ~28.8% weight loss across three degradation stages, confirming enhanced thermal stability. In vitro cytocompatibility testing using L929 fibroblasts validated the biocompatibility of the composites. Collectively, the synergy between bioceramics and biopolymers markedly improved both mechanical and thermal performance. These findings position the nHA/CS/CoL scaffold as a promising candidate for clinical applications in dental tissue regeneration. Unlike conventional grafting materials, this study introduces a synergistically optimized nHA/CS/CoL bio-ink formulation specifically designed for extrusion-based 3D bioprinting of patient-specific dental constructs. The core innovation lies in the precise integration of nHA within a dual-polymer matrix (CS/CoL), which bridges the gap between mechanical resilience and biological signaling, achieving a compressive strength that mimics native alveolar bone while maintaining high cytocompatibility. Full article
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19 pages, 3610 KB  
Article
Effects of Thermal Aging on Optical, Surface, Mechanical, and Biological Properties of CAD/CAM Polymer-Based Dental Materials
by Gül Ateş and Mustafa Gungormus
Polymers 2026, 18(6), 760; https://doi.org/10.3390/polym18060760 - 20 Mar 2026
Viewed by 689
Abstract
CAD/CAM polymer-based dental materials are increasingly used as metal-free alternatives for fixed and implant-supported restorations. High-performance polymers such as polyetheretherketone (PEEK), fiber-reinforced composites, and graphene-reinforced polymers have been introduced to improve material stability; however, evidence regarding the effects of thermal aging on their [...] Read more.
CAD/CAM polymer-based dental materials are increasingly used as metal-free alternatives for fixed and implant-supported restorations. High-performance polymers such as polyetheretherketone (PEEK), fiber-reinforced composites, and graphene-reinforced polymers have been introduced to improve material stability; however, evidence regarding the effects of thermal aging on their physicochemical and biological properties remains limited. In this study, PEEK, a fiber-reinforced composite (FRC), and a graphene-reinforced PMMA-based polymer (G-CAM) were evaluated. Twenty-seven disc-shaped specimens (10 × 2 mm; n = 9 per material) were fabricated and subjected to 10,000 thermal cycles between 5 and 55 °C. Color change (ΔE00), surface roughness (Ra), and Vickers microhardness (VHN) were measured before and after aging. Chemical stability was assessed using FTIR and Raman spectroscopy, surface morphology by SEM analysis, and biological safety by cytotoxicity testing. Material-dependent differences were observed in color stability, surface roughness, and microhardness after thermal aging (p < 0.05). Microhardness decreased in the fiber-reinforced and graphene-reinforced materials, whereas PEEK showed no significant change. Spectroscopic analyses indicated preserved chemical structure, and all materials demonstrated acceptable cytocompatibility. Thermal aging influenced material behavior while chemical stability and biological safety were maintained, highlighting the importance of considering aging behavior during material selection for prosthetic restorations. Full article
(This article belongs to the Section Polymer Analysis and Characterization)
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20 pages, 739 KB  
Article
Bisphenol-A Release from Modern Resin-Based Dental Composites: A Time-Dependent In Vitro Assessment
by Angelo Aliberti, Fabiana Di Duca, Mirko Piscopo, Pietro Ausiello, Luigi Ausiello, Alfonso Acerra and Lucia Grumetto
Polymers 2026, 18(6), 707; https://doi.org/10.3390/polym18060707 - 14 Mar 2026
Cited by 1 | Viewed by 869
Abstract
Resin-based dental composites are widely used in restorative dentistry; however, concerns persist regarding their potential release of Bisphenol-A (BPA), a compound with recognized endocrine-disrupting activity. This in vitro study evaluated the time-dependent release of BPA from four contemporary resin-based dental filling composites immersed [...] Read more.
Resin-based dental composites are widely used in restorative dentistry; however, concerns persist regarding their potential release of Bisphenol-A (BPA), a compound with recognized endocrine-disrupting activity. This in vitro study evaluated the time-dependent release of BPA from four contemporary resin-based dental filling composites immersed in artificial saliva under different thermal conditions. Disk-shaped specimens (5.5 mm diameter and 2 mm thickness) of Estelite Sigma Quick, Clearfil Majesty ES-2, Omnichroma Flow, and Luna 2 were incubated in artificial saliva at physiological pH (6.8) at 37 °C and 44 °C. BPA concentrations were quantified after 1, 7, and 28 days using a validated UHPLC–MS/MS method. BPA release was observed for all materials except Luna 2, for which it remained below the limit of quantification (LOQ) at all time points and temperatures. Across all BPA-releasing composites, the highest concentrations were observed after 1 day of immersion, particularly at 44 °C. Estelite Sigma Quick exhibited the highest BPA release, followed by Clearfil Majesty ES-2 and Omnichroma Flow. BPA release decreased progressively over time for all materials. Statistical analysis confirmed significant effects of material type, temperature, and exposure duration on BPA release (p < 0.001). Within the limitations of this in vitro study, BPA release appears to be material-dependent and influenced by thermal conditions and immersion time. Although absolute BPA concentrations were low, these findings highlight the importance of material-specific evaluation and continued monitoring of potential sources of cumulative BPA exposure from restorative dental materials. Full article
(This article belongs to the Special Issue Recent Advances in Dental Resin-Based Polymers)
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32 pages, 993 KB  
Review
A Comprehensive Review of Polymeric Materials and Additive Manufacturing in Dental Crown Fabrication: State of the Art, Challenges, and Opportunities
by Faisal Khaled Aldawood
Polymers 2026, 18(6), 667; https://doi.org/10.3390/polym18060667 - 10 Mar 2026
Viewed by 1002
Abstract
For decades, zirconia- and ceramic-based materials have dominated dental crown fabrication due to their durability and aesthetic appeal. However, a fundamental shift is occurring as polymeric alternatives emerge with notable advantages: better adhesive bonding, versatile aesthetics, lower costs, and a lighter weight. The [...] Read more.
For decades, zirconia- and ceramic-based materials have dominated dental crown fabrication due to their durability and aesthetic appeal. However, a fundamental shift is occurring as polymeric alternatives emerge with notable advantages: better adhesive bonding, versatile aesthetics, lower costs, and a lighter weight. The advances in polymer chemistry and additive manufacturing have significantly impacted prosthodontics, allowing the rapid creation of highly customized, patient-specific restorations with a precision previously impossible (achieved through advanced Computer-Aided Design software and standardized 3D-printing equipment) with traditional methods. This review provides a detailed analysis of 3D-printed polymeric dental crowns from various angles. It explores the materials science behind different polymers, compares manufacturing methods, and evaluates the mechanical performance and biocompatibility. Despite the progress, polymeric materials still fall short of matching the mechanical properties of advanced ceramics, especially in compressive strength and wear resistance. Moreover, there is limited long-term clinical data over five to ten years. The lack of standardized testing protocols complicates cross-study comparisons, and the regulatory pathways for patient-specific 3D-printed devices are still developing, creating uncertainty for manufacturers and clinicians. The future prospective looks promising in many ways such as innovations like four-dimensional printing, where materials respond dynamically to environmental stimuli, which could enable crowns that adapt to changing oral conditions. Nanocomposites with functionalized nanoparticles might enhance mechanical properties while maintaining printability. AI-driven design optimization could automate and improve the crown morphology, occlusal contacts, and fit. Incorporating bioactive materials could turn crowns into active therapeutic devices that promote remineralization and combat bacterial colonization. This review summarizes the current knowledge, highlights the key gaps, and suggests steps toward establishing polymeric 3D-printed crowns as viable long-term alternatives capable of competing with or surpassing traditional ceramic options. Full article
(This article belongs to the Special Issue Polymer Microfabrication and 3D/4D Printing)
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14 pages, 6894 KB  
Article
Microhardness Enhancement in Polymer Composites via BaZrO3-Based Ceramic Reinforcement
by Houda Ali Gamoudi, Vesna Radojevic, Aleksandar Stajcic, Milos Petrovic, Bojana Simovic, Dusica B. Stojanovic and Ivana Stajcic
Appl. Sci. 2026, 16(5), 2529; https://doi.org/10.3390/app16052529 - 6 Mar 2026
Viewed by 485
Abstract
Defect-tolerant oxide ceramics offer an alternative reinforcement strategy for high-performance polymer composites beyond conventional silica- and zirconia-based systems. In this work, a novel BaZrO3-Y2O3-SrTiO3 (BZYS) ceramic hybrid was introduced as a reinforcing phase in a polyetherimide [...] Read more.
Defect-tolerant oxide ceramics offer an alternative reinforcement strategy for high-performance polymer composites beyond conventional silica- and zirconia-based systems. In this work, a novel BaZrO3-Y2O3-SrTiO3 (BZYS) ceramic hybrid was introduced as a reinforcing phase in a polyetherimide (PEI) matrix to evaluate its effect on interphase formation, thermal stability and mechanical performance. BZYS powders were prepared by ball milling and incorporated at 1 and 3 wt% into solution-cast PEI films. X-ray diffraction confirmed the preservation of the BaZrO3 perovskite structure after mechanical activation, with a slight lattice expansion, indicating partial ion incorporation and defect-mediated structural accommodation. SEM analysis revealed predominantly submicron agglomerates with homogeneous dispersion at low loading and controlled agglomeration at higher content. Differential scanning calorimetry demonstrated a systematic increase in glass transition temperature from 202.0 °C for neat PEI to 210.4 °C and 212.0 °C for 1 wt% and 3 wt% composites, respectively, evidencing restricted segmental mobility and interphase formation. Instrumented microindentation showed substantial hardness enhancement of 40% and 83% for 1 wt% and 3 wt% reinforcement, respectively (p < 0.05), with a strong linear dependence on filler content (R2 = 0.9845). The results demonstrate that chemically stable, strain-tolerant BZYS ceramics effectively promote interphase-mediated reinforcement in PEI, establishing a novel oxide-based pathway for mechanically enhanced dental composite materials design. Full article
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21 pages, 6149 KB  
Article
New Mathematical Model for Correlation Between Tensile Elastic Modulus and Shore “A” and “00” Hardness for Flexible Polymers
by Josip Hoster, Nikola Šimunić, Tihana Kostadin and Bruno Vojnović
Polymers 2026, 18(5), 620; https://doi.org/10.3390/polym18050620 - 1 Mar 2026
Cited by 1 | Viewed by 859
Abstract
The paper presents the development of a correlation model for initial tensile elastic modulus for flexible polymers as a function of Shore hardness in OO and A scale based on measurement. Measured polymers are in groups of silicone rubber, nitrile butadiene rubber (NBR), [...] Read more.
The paper presents the development of a correlation model for initial tensile elastic modulus for flexible polymers as a function of Shore hardness in OO and A scale based on measurement. Measured polymers are in groups of silicone rubber, nitrile butadiene rubber (NBR), thermoplastic polyurethane (TPU) and silicone. The model is composed of piecewise exponential functions with fixed coefficients chosen to minimize the S2 error norm and absolute value of relative error at the measured data points. Every chosen section of the hardness scale has one exponential function correlating the hardness to tensile elastic modulus with the argument in the form of a polynomial up to the fourth degree. The coefficients for the polynomial arguments were determined by enforcing interpolation conditions in a chosen set of points in the logarithmic scale for the elastic modulus. The correlation model possesses C0 continuity. For each material, five specimens were used for hardness measurements and five for the elastic modulus testing. The correlation model gives a positive value for elastic modulus of 0 for hardness, and a “finite”, “reasonable” value of 100 for hardness and is monotonic. Tensile properties were evaluated using true stress and logarithmic (Hencky) strain, with iterative correction of the changing cross-sectional area to account for large strain. The maximum relative error achieved in the correlation model for the OO scale is 13.4%, while for the A scale it is 7%. The developed model provides a practical and rapid method for estimating the initial tensile elastic modulus from non-destructive hardness measurements and is particularly useful in industrial applications and in the development of material models for dental surgery simulations. Full article
(This article belongs to the Section Polymer Analysis and Characterization)
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28 pages, 405 KB  
Review
Finite Element Analysis in Polymer-Based Adhesive Dental Restorations: A Narrative Review on Material Behavior, Methodological Validity, and Clinical Relevance
by Angelo Aliberti, Mario Caggiano, Mirko Piscopo, Roberta Gasparro, Mariangela Cernera, Niccoló Giuseppe Armogida and Pietro Ausiello
Polymers 2026, 18(5), 580; https://doi.org/10.3390/polym18050580 - 27 Feb 2026
Viewed by 682
Abstract
Finite element analysis (FEA) is increasingly used in conservative and restorative dentistry to investigate the mechanical behavior of adhesive direct and indirect polymer-based restorations. Despite the growing number of FEA-based studies, the literature currently lacks a dedicated critical synthesis specifically addressing the methodological [...] Read more.
Finite element analysis (FEA) is increasingly used in conservative and restorative dentistry to investigate the mechanical behavior of adhesive direct and indirect polymer-based restorations. Despite the growing number of FEA-based studies, the literature currently lacks a dedicated critical synthesis specifically addressing the methodological validity and clinical interpretability of FEA in adhesive restorative dentistry. This narrative review critically examines the current literature on the application of FEA in adhesive restorative dentistry, with particular attention to class I to class V cavities in anterior and posterior teeth restored with direct or indirect polymeric materials, including inlays, onlays, overlays, and tabletop restorations. A structured, non-systematic search of major databases was conducted, and selected studies were qualitatively appraised with emphasis on modeling assumptions, stress distribution, and clinical meaning. Unlike previous broad overviews of dental biomechanics, this review provides a clinically oriented framework for interpreting FEA findings across restorative strategies. FEA consistently identifies trends related to cavity configuration, cuspal support, restoration design, material stiffness, polymerization shrinkage, and adhesive interface behavior, helping to explain clinically observed failure patterns and supporting minimally invasive approaches. However, simplified material models, idealized bonding conditions, and static loading protocols limit prediction of long-term performance. When interpreted within these constraints and integrated with experimental and clinical evidence, FEA remains a valuable complementary tool for rational restorative decision-making. Full article
(This article belongs to the Special Issue Advanced Polymeric Materials for Dental Applications III)
13 pages, 661 KB  
Article
Impact of Various Mouthwashes on the Color Stability of Hybrid Ceramic and Reinforced Composite CAD/CAM Restorative Materials: An In Vitro Study
by Raul Rotar, Adrian Cândea, Alexandra Măroiu, Andrei-Bogdan Faur, Cristiana Cuzic, Roxana-Elena Rotar and Anca Jivănescu
Materials 2026, 19(4), 758; https://doi.org/10.3390/ma19040758 - 15 Feb 2026
Cited by 1 | Viewed by 517
Abstract
Caries control is essential for the long-term success of dental restorations, and the frequent use of mouthwashes may influence the esthetic properties of restorative materials. This study aimed to evaluate the effect of several commercially available mouthwashes on the color stability of resin-based [...] Read more.
Caries control is essential for the long-term success of dental restorations, and the frequent use of mouthwashes may influence the esthetic properties of restorative materials. This study aimed to evaluate the effect of several commercially available mouthwashes on the color stability of resin-based CAD/CAM restorative materials. Three CAD/CAM materials were investigated: a hybrid ceramic (Cerasmart), a polymer-infiltrated ceramic (Vita Enamic), and a reinforced composite (Brilliant Crios). Rectangular specimens were immersed in Eludril Classic, Listerine Total Care, Listerine Advanced White, and distilled water (control). Color measurements were performed at baseline and after immersion periods up to 24 h using a digital spectrophotometer, and color differences (ΔE00) were calculated. Statistical analysis revealed that both mouthwash type and immersion time had a statistically significant effect on color change (p ≤ 0.05). All tested materials exhibited ΔE00 values exceeding the clinically acceptable threshold. These findings suggest that prolonged mouthwash use may compromise the esthetic longevity of resin-based CAD/CAM restorations. The null hypothesis was that prolonged use of mouthwash does not influence the color of resin-based CAD/CAM materials especially for those containing alcohol. Full article
(This article belongs to the Special Issue Innovations in Digital Dentistry: Novel Materials and Technologies)
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14 pages, 280 KB  
Review
Next-Gen Restorative Materials to Revolutionise Smiles
by John Yun Niu, Kelsey Xingyun Ge, Iris Xiaoxue Yin, Olivia Lili Zhang, Irene Shuping Zhao and Chun Hung Chu
Bioengineering 2026, 13(2), 143; https://doi.org/10.3390/bioengineering13020143 - 27 Jan 2026
Cited by 2 | Viewed by 1565
Abstract
Recent breakthroughs in materials science have driven transformative advancements in restorative dentistry. Advanced dental materials, such as bioactive materials, nanocomposites, and fibre-reinforced composites, are attracting attention. Bioactive materials, such as calcium silicate-based cements and bioactive glass, represent a paradigm shift by interacting with [...] Read more.
Recent breakthroughs in materials science have driven transformative advancements in restorative dentistry. Advanced dental materials, such as bioactive materials, nanocomposites, and fibre-reinforced composites, are attracting attention. Bioactive materials, such as calcium silicate-based cements and bioactive glass, represent a paradigm shift by interacting with biological tissues to stimulate regeneration. They promote hydroxyapatite formation, accelerating mineralisation in hard and soft tissues, and are pivotal tools in minimally invasive procedures due to their functions of structural support and biological interaction. Nanomaterials, especially nanocomposites with embedded nanoparticles, effectively address polymerisation shrinkage and wear in traditional composites. With just 1.5% shrinkage, a flexural strength over 150 MPa, and 44–60% higher wear resistance than conventional composites, they offer significant improvements. Nanocomposites also provide enamel-like translucency and a bond strength of 27–38 MPa to dentin, ensuring excellent aesthetics and durability—making them ideal for direct restorations. Fibre-reinforced composites with glass or polymer fibres balance aesthetics with strength and are increasingly used in restorations. Their high fracture resistance, which closely approaches that of a natural tooth, enables clinicians to preserve more healthy teeth during restoration, in line with the principles of modern conservative dentistry. Overall, bioactive materials enhance tissue repair, nanocomposites optimise form and function, and fibre-reinforced composites deliver strength without compromising aesthetics. As these materials transition from research to clinical practice, they promise longer-lasting treatments, fewer complications, and higher patient satisfaction. This narrative review aims to explore three types of advanced dental materials and their role in improving clinical outcomes. Full article
(This article belongs to the Special Issue Advanced Dental Materials for Restorative Dentistry)
13 pages, 2145 KB  
Article
Dual-Target Antimicrobial Strategy Combining Cell-Penetrating Protamine Peptides and Membrane-Active ε-Poly-L-lysine
by Ryosuke Nakamura, Rie Togawa, Daisuke Koizumi, Masataka Kawarasaki, Keishi Iohara and Michiyo Honda
Micro 2026, 6(1), 7; https://doi.org/10.3390/micro6010007 - 21 Jan 2026
Viewed by 626
Abstract
Dental caries is a major global health issue associated with biofilm formation by Streptococcus mutans (S. mutans). Conventional antimicrobials often fail to eliminate biofilms due to their structural resistance, highlighting the need for new strategies. This study investigated the antibacterial and [...] Read more.
Dental caries is a major global health issue associated with biofilm formation by Streptococcus mutans (S. mutans). Conventional antimicrobials often fail to eliminate biofilms due to their structural resistance, highlighting the need for new strategies. This study investigated the antibacterial and antibiofilm effects of protamine peptides (PPs), which are cell-penetrating antimicrobial peptides derived from salmon protamine, alone and in combination with antimicrobial agents. Antimicrobial susceptibility was evaluated using alamarBlue® and colony count assays, while biofilm formation was analyzed using crystal violet staining, confocal microscopy, and extracellular polysaccharide (EPS) quantification. PP exhibited moderate antibacterial activity but strongly suppressed EPS accumulation and biofilm development, leading to a flattened biofilm structure. Cotreatment with ε-poly-L-lysine (PL) significantly enhanced antibacterial and antibiofilm effects compared with either agent alone, whereas this effect was not observed with other cationic polymers. Fluorescence imaging revealed that PL promoted the intracellular localization of PP without increasing membrane damage, indicating a cooperative mechanism by which PL enhances membrane permeability and PP targets intracellular sites. These findings demonstrate that combining a cell-penetrating peptide with a membrane-active agent is a novel approach to overcome bacterial tolerance. The PP–PL combination effectively suppressed S. mutans growth and biofilm formation through dual action on membranes and EPS metabolism, offering a promising basis for the development of peptide-based preventive agents and biofilm-resistant dental materials. Full article
(This article belongs to the Section Microscale Biology and Medicines)
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33 pages, 405 KB  
Review
Contemporary Use of Polymers in Dentistry: A Narrative Review
by Svetla Ivanova, Zlatina Tomova, Angelina Vlahova, Iliyana L. Stoeva, Elena Vasileva, Yordanka Uzunova, Magdalina Urumova, Desislav Tomov and Atanas Chonin
Polymers 2026, 18(1), 138; https://doi.org/10.3390/polym18010138 - 2 Jan 2026
Cited by 6 | Viewed by 2587
Abstract
This narrative review examines contemporary applications of polymeric materials in dentistry from 2020 to 2025, spanning prosthodontics, restorative dentistry, orthodontics, endodontics, implantology, diagnostics, and emerging technologies. We searched PubMed, Scopus, Web of Science, and Embase for peer reviewed English language articles and synthesized [...] Read more.
This narrative review examines contemporary applications of polymeric materials in dentistry from 2020 to 2025, spanning prosthodontics, restorative dentistry, orthodontics, endodontics, implantology, diagnostics, and emerging technologies. We searched PubMed, Scopus, Web of Science, and Embase for peer reviewed English language articles and synthesized evidence on polymer classes, processing routes, mechanical and chemical behavior, and clinical performance. Approximately 116 articles were included. Polymers remain central to clinical practice: poly methyl methacrylate (PMMA) is still widely used for dentures, high performance systems such as polyether ether ketone (PEEK) are expanding framework and implant-related indications, and resin composites and adhesives continue to evolve through nanofillers and bioactive formulations aimed at improved durability and reduced secondary caries. Thermoplastic polyurethane and copolyester systems drive clear aligner therapy, while polymer-based obturation materials and fiber-reinforced posts support endodontic rehabilitation. Additive manufacturing and computer aided design computer aided manufacturing (CAD CAM) enable customized prostheses and surgical guides, and sustainability trends are accelerating interest in biodegradable or recyclable dental polymers. Across domains, evidence remains heterogeneous and clinical translation depends on balancing strength, esthetics, biocompatibility, aging behavior, and workflow constraints. Full article
(This article belongs to the Special Issue Polymers Strategies in Dental Therapy)
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