Skip to Content

300 Results Found

  • Article
  • Open Access
61 Citations
8,058 Views
14 Pages

Biodegradation Studies of Polyhydroxybutyrate and Polyhydroxybutyrate-co-Polyhydroxyvalerate Films in Soil

  • Jihyeon Kim,
  • Nevin S. Gupta,
  • Lindsey B. Bezek,
  • Jacqueline Linn,
  • Karteek K. Bejagam,
  • Shounak Banerjee,
  • Joseph H. Dumont,
  • Sang Yong Nam,
  • Hyun Woo Kang and
  • Kwan-Soo Lee
  • + 4 authors

Due to increased environmental pressures, significant research has focused on finding suitable biodegradable plastics to replace ubiquitous petrochemical-derived polymers. Polyhydroxyalkanoates (PHAs) are a class of polymers that can be synthesized b...

  • Article
  • Open Access
9 Citations
3,765 Views
13 Pages

Characterization of Polyhydroxybutyrate-Based Composites Prepared by Injection Molding

  • Marcos M. Hernandez,
  • Nevin S. Gupta,
  • Kwan-Soo Lee,
  • Aaron C. Pital,
  • Babetta L. Marrone,
  • Carl N. Iverson and
  • Joseph H. Dumont

18 December 2021

The waste generated by single-use plastics is often non-recyclable and non-biodegradable, inevitably ending up in our landfills, ecosystems, and food chain. Through the introduction of biodegradable polymers as substitutes for common plastics, we can...

  • Review
  • Open Access
15 Citations
4,552 Views
15 Pages

Polyhydroxybutyrate Metabolism in Azospirillum brasilense and Its Applications, a Review

  • María de los Ángeles Martínez Martínez,
  • Lucía Soto Urzúa,
  • Yovani Aguilar Carrillo,
  • Mirian Becerril Ramírez and
  • Luis Javier Martínez Morales

13 July 2023

Gram-negative Azospirillum brasilense accumulates approximately 80% of polyhydroxybutyrate (PHB) as dry cell weight. For this reason, this bacterium has been characterized as one of the main microorganisms that produce PHB. PHB is synthesized inside...

  • Communication
  • Open Access
8 Citations
4,599 Views
8 Pages

Biosynthesis of Polyhydroxybutyrate with Cellulose Nanocrystals Using Cupriavidus necator

  • Giyoung Shin,
  • Da-Woon Jeong,
  • Hyeri Kim,
  • Seul-A Park,
  • Semin Kim,
  • Ju Young Lee,
  • Sung Yeon Hwang,
  • Jeyoung Park and
  • Dongyeop X. Oh

5 August 2021

Polyhydroxybutyrate (PHB) is a natural polyester synthesized by several microorganisms. Moreover, it has excellent biodegradability and is an eco-friendly material because it converts water and carbon dioxide as final decomposition products. However,...

  • Article
  • Open Access
8 Citations
2,710 Views
18 Pages

A Novel Sphingomonas sp. Isolated from Argan Soil for the Polyhydroxybutyrate Production from Argan Seeds Waste

  • Amina Aragosa,
  • Benedetta Saccomanno,
  • Valeria Specchia and
  • Mariaenrica Frigione

18 January 2023

Polyhydroxybutyrate (PHB) is a biodegradable bio-based polymer synthesized by microorganisms under unfavorable conditions from agro-industrial residues as a source of carbon. These aspects make the bio-based polymer attractive for the mass production...

  • Article
  • Open Access
7 Citations
3,008 Views
18 Pages

Polyhydroxybutyrate Rice Hull and Torrefied Rice Hull Biocomposites

  • Zach McCaffrey,
  • Andrew Cal,
  • Lennard Torres,
  • Bor-Sen Chiou,
  • Delilah Wood,
  • Tina Williams and
  • William Orts

17 September 2022

Raw and torrefied rice hulls (RRH and TRH) were incorporated into polyhydroxybutyrate (PHB) as fillers using extrusion and injection molding to produce biomass-polymer composites. Filler and composite materials were characterized by particle size ana...

  • Article
  • Open Access
12 Citations
6,379 Views
9 Pages

Stabilization of Iron (Micro)Particles with Polyhydroxybutyrate for In Situ Remediation Applications

  • Laura Chronopoulou,
  • Cleofe Palocci,
  • Francesco Valentino,
  • Ida Pettiti,
  • Stanisław Wacławek,
  • Miroslav Černík and
  • Marco Petrangeli Papini

9 December 2016

Groundwater is an extremely important resource that may, however, contain a variety of toxic and bioaccumulative contaminants. Traditional “Pump and Treat” technologies for treating contaminated groundwater are no longer time- or cost-effective; ther...

  • Article
  • Open Access
24 Citations
6,085 Views
15 Pages

Optimization of Polyhydroxybutyrate Production by Amazonian Microalga Stigeoclonium sp. B23

  • Murilo Moraes Mourão,
  • Diana Gomes Gradíssimo,
  • Agenor Valadares Santos,
  • Maria Paula Cruz Schneider,
  • Silvia Maria Mathes Faustino,
  • Vitor Vasconcelos and
  • Luciana Pereira Xavier

3 December 2020

The present work established the optimization and production of biodegradable thermoplastic polyhydroxybutyrate (PHB) from Amazonian microalga Stigeoclonium sp. B23. The optimization was performed in eight different growth media conditions of Stigeoc...

  • Article
  • Open Access
122 Citations
8,857 Views
21 Pages

Effects of Cellulose Nanocrystals and Cellulose Nanofibers on the Structure and Properties of Polyhydroxybutyrate Nanocomposites

  • Bobo Zhang,
  • Chongxing Huang,
  • Hui Zhao,
  • Jian Wang,
  • Cheng Yin,
  • Lingyun Zhang and
  • Yuan Zhao

11 December 2019

One of the major obstacles for polyhydroxybutyrate (PHB), a biodegradable and biocompatible polymer, in commercial applications is its poor elongation at break (~3%). In this study, the effects of nanocellulose contents and their types, including cel...

  • Article
  • Open Access
46 Citations
7,819 Views
13 Pages

Tequila Agave Bagasse Hydrolysate for the Production of Polyhydroxybutyrate by Burkholderia sacchari

  • Yolanda González-García,
  • Janessa Grieve,
  • Juan Carlos Meza-Contreras,
  • Berenice Clifton-García and
  • José Antonio Silva-Guzman

Tequila agave bagasse (TAB) is the fibrous waste from the Tequila production process. It is generated in large amounts and its disposal is an environmental problem. Its use as a source of fermentable sugars for biotechnological processes is of intere...

  • Article
  • Open Access
45 Citations
5,682 Views
12 Pages

14 February 2021

This work considers the application of eco-friendly, biodegradable materials based on polylactide (PLA) and polyhydroxybutyrate (PHB), instead of conventional polymeric materials, in order to prevent further environmental endangerment by accumulation...

  • Article
  • Open Access
15 Citations
3,160 Views
17 Pages

Antibacterial Composite Material Based on Polyhydroxybutyrate and Zn-Doped Brushite Cement

  • Inna V. Fadeeva,
  • Dina V. Deyneko,
  • Alexander V. Knotko,
  • Anatoly A. Olkhov,
  • Pavel V. Slukin,
  • Galina A. Davydova,
  • Taisiia A. Trubitsyna,
  • Ilya I. Preobrazhenskiy,
  • Alevtina N. Gosteva and
  • Julietta V. Rau
  • + 1 author

28 April 2023

A composite material based on electrospinning printed polyhydroxybutyrate fibers impregnated with brushite cement containing Zn substitution was developed for bone implant applications. Powder X-ray Diffraction (PXRD), Fourier Transform Infrared Spec...

  • Review
  • Open Access
10 Citations
3,489 Views
23 Pages

20 November 2025

The non-degradable polymers used in daily and commercial application are generally inexpensive; however, their excessive use leads to extensive environmental damage. In light of this, the demand for bio-derived, biocompatible, and biodegradable polym...

  • Article
  • Open Access
7 Citations
2,826 Views
27 Pages

1 October 2023

Polyhydroxybutyrate (PHB) is a promising biopolymer. However, processing PHB in pure form in thermoplastic processes is limited due to its rapid degradation, very low initial crystallization rate, strong post-crystallization, and its low final stretc...

  • Article
  • Open Access
3 Citations
2,021 Views
14 Pages

Effects of 5 wt.% Polycaprolactone, Polyhydroxybutyrate and Polyvinyltrimethoxysilane on the Properties of Ag/Zn/Mg Alloy

  • Marzieh Rabiei,
  • Motahareh Sadat Raziyan,
  • Reza Ebrahimi-Kahrizsangi,
  • Sohrab Nasiri,
  • Arvydas Palevicius,
  • Giedrius Janusas and
  • Andrius Vilkauskas

5 August 2022

Mg-based alloys have several suitable properties for biomaterials, but they have major problems of being less antibacterial and have a low mechanical strength. To solve these problems, a new combination of Ag/Zn/Mg was prepared in this study, where t...

  • Article
  • Open Access
589 Views
16 Pages

This study systematically optimised extrusion-printing parameters for polyhydroxybutyrate (PHB) using a Design of Experiment (DoE) approach to improve printability and construct fidelity. A five-factor DoE was conducted to evaluate the individual and...

  • Article
  • Open Access
8 Citations
3,180 Views
17 Pages

Enhanced Natural Attenuation of Groundwater Cr(VI) Pollution Using Electron Donors: Yeast Extract vs. Polyhydroxybutyrate

  • Marina Tumolo,
  • Angela Volpe,
  • Natalia Leone,
  • Pietro Cotugno,
  • Domenico De Paola,
  • Daniela Losacco,
  • Vito Locaputo,
  • Maria Concetta de Pinto,
  • Vito Felice Uricchio and
  • Valeria Ancona

Remediation interventions based on the native bacteria’s capability to reduce Cr(VI) represent a valid strategy in terms of economic and environmental sustainability. In this study, a bioremediation test was carried out using viable microcosms...

  • Article
  • Open Access
28 Citations
4,513 Views
15 Pages

Finding of Novel Galactose Utilizing Halomonas sp. YK44 for Polyhydroxybutyrate (PHB) Production

  • Hee Ju Jung,
  • Su Hyun Kim,
  • Do Hyun Cho,
  • Byung Chan Kim,
  • Shashi Kant Bhatia,
  • Jongbok Lee,
  • Jong-Min Jeon,
  • Jeong-Jun Yoon and
  • Yung-Hun Yang

10 December 2022

Polyhydroxybutyrate (PHB) is a biodegradable bioplastic with potential applications as an alternative to petroleum-based plastics. However, efficient PHB production remains difficult. The main cost of PHB production is attributed to carbon sources; h...

  • Article
  • Open Access
2 Citations
1,903 Views
11 Pages

Polyhydroxybutyrate as a Novel Biopolymer for Dental Restorative Materials: Biological and Morphological Analysis

  • Cigdem Atalayin Ozkaya,
  • Beliz Ertan,
  • Gizem Kaftan Ocal,
  • Guliz Armagan,
  • Gokhan Gungor,
  • Murat Demirbilek,
  • Huseyin Tezel,
  • Vincenzo Notaro,
  • Nicola Scotti and
  • Andrea Baldi

24 January 2025

Polyhydroxybutyrate (PHB) is a biopolymer produced by bacteria. This study aimed to implement the production process of experimental medical-grade PHB and to evaluate its morphology and biocompatibility compared to conventional resin-based composites...

  • Article
  • Open Access
10 Citations
3,603 Views
12 Pages

Development of Optogenetic Dual-Switch System for Rewiring Metabolic Flux for Polyhydroxybutyrate Production

  • Sumeng Wang,
  • Yue Luo,
  • Wei Jiang,
  • Xiaomeng Li,
  • Qingsheng Qi and
  • Quanfeng Liang

18 January 2022

Several strategies, including inducer addition and biosensor use, have been developed for dynamical regulation. However, the toxicity, cost, and inflexibility of existing strategies have created a demand for superior technology. In this study, we des...

  • Article
  • Open Access
18 Citations
6,053 Views
22 Pages

Mechanical and Structural Properties of Polyhydroxybutyrate as Additive in Blend Material in Additive Manufacturing for Medical Applications

  • Muhammad Zulhilmi Zainuddin,
  • Ahmad Adnan Abu Bakar,
  • Ahmad Nurhelmy Adam,
  • Shahino Mah Abdullah,
  • Nizam Tamchek,
  • Muhammad Syafiq Alauddin,
  • Mohd Muzamir Mahat,
  • Nophadon Wiwatcharagoses,
  • Ahmad Alforidi and
  • Mohd Ifwat Mohd Ghazali

12 April 2023

Today, additive manufacturing (AM) is considered one of the vital tenets of the industry 4.0 revolution due to its high productivity, decentralized production and rapid prototyping. This work aims to study the mechanical and structural properties of...

  • Article
  • Open Access
8 Citations
2,989 Views
17 Pages

The intended circular economy for plastics envisages that they will be partially replaced by bio-based polymers in the future. In this work, the natural polyester polyhydroxybutyrate (PHB) was produced by Azohydromonas lata using cheese whey (CW) as...

  • Article
  • Open Access
16 Citations
4,866 Views
15 Pages

16 February 2024

In this work, we have studied the potential application for 3D-printing of a polymer made from combining a biodegradable and biocompatible polymer (i.e., polyhydroxybutyrate, PHB) with natural bio-based fiber (i.e., cellulose). To this end, a masterb...

  • Article
  • Open Access
14 Citations
5,682 Views
21 Pages

One-Step Oxidation of Orange Peel Waste to Carbon Feedstock for Bacterial Production of Polyhydroxybutyrate

  • Maryam Davaritouchaee,
  • Imann Mosleh,
  • Younas Dadmohammadi and
  • Alireza Abbaspourrad

30 January 2023

Orange peels are an abundant food waste stream that can be converted into useful products, such as polyhydroxyalkanoates (PHAs). Limonene, however, is a key barrier to building a successful biopolymer synthesis from orange peels as it inhibits microb...

  • Feature Paper
  • Article
  • Open Access
26 Citations
8,665 Views
18 Pages

30 December 2016

This study reports on the development of bio-based hydrophobic coatings for packaging papers through deposition of polyhydroxybutyrate (PHB) particles in combination with nanofibrillated cellulose (NFC) and plant wax. In the first approach, PHB parti...

  • Article
  • Open Access
154 Views
16 Pages

Dried okara (DOK), a lignocellulosic byproduct from tofu production, was evaluated as both a carbon source and culture medium to enable cost-effective polyhydroxybutyrate (PHB) production. Hydrolysis with either HCl or H2SO4 generated 48–51 g/L...

  • Article
  • Open Access
89 Citations
11,313 Views
18 Pages

Metabolic Changes in Synechocystis PCC6803 upon Nitrogen-Starvation: Excess NADPH Sustains Polyhydroxybutyrate Accumulation

  • Waldemar Hauf,
  • Maximilian Schlebusch,
  • Jan Hüge,
  • Joachim Kopka,
  • Martin Hagemann and
  • Karl Forchhammer

6 February 2013

Polyhydroxybutyrate (PHB) is a common carbon storage polymer among heterotrophic bacteria. It is also accumulated in some photoautotrophic cyanobacteria; however, the knowledge of how PHB accumulation is regulated in this group is limited. PHB synthe...

  • Article
  • Open Access
6 Citations
4,372 Views
18 Pages

Alkaline-Tolerant Bacillus cereus 12GS: A Promising Polyhydroxybutyrate (PHB) Producer Isolated from the North of Mexico

  • Gustavo de J. San Miguel-González,
  • María E. Alemán-Huerta,
  • Raul E. Martínez-Herrera,
  • Isela Quintero-Zapata,
  • Susana de la Torre-Zavala,
  • Hamlet Avilés-Arnaut,
  • Fátima L. Gandarilla-Pacheco and
  • Erick de J. de Luna-Santillana

Environmental pollution caused by petroleum-derived plastics continues to increase annually. Consequently, current research is interested in the search for eco-friendly bacterial polymers. The importance of Bacillus bacteria as producers of polyhydro...

  • Article
  • Open Access
40 Citations
12,212 Views
10 Pages

18 April 2011

Polyhydroxybutyrate (PHB) is one of the polyhydroxyalkanoates (PHAs) which has biodegradable and biocompatible properties. They are adopted in the biomedical field, in, for example, medical implants and drug delivery carriers. This study seeks to pro...

  • Article
  • Open Access
29 Citations
3,872 Views
14 Pages

Finding a Benign Plasticizer to Enhance the Microbial Degradation of Polyhydroxybutyrate (PHB) Evaluated by PHB Degrader Microbulbifer sp. SOL66

  • Jang Yeon Cho,
  • Su Hyun Kim,
  • Hee Ju Jung,
  • Do Hyun Cho,
  • Byung Chan Kim,
  • Shashi Kant Bhatia,
  • Jungoh Ahn,
  • Jong-Min Jeon,
  • Jeong-Jun Yoon and
  • Yung-Hun Yang
  • + 1 author

1 September 2022

As a biodegradable plastic, polyhydroxybutyrate (PHB) has relatively poor mechanical properties, preventing its wider use. Various plasticizers have been studied to improve the mechanical properties of PHB; however, due to the slow degradation speed...

  • Article
  • Open Access
12 Citations
2,641 Views
21 Pages

Biodegradation of Polyhydroxybutyrate, Polylactide, and Their Blends by Microorganisms, Including Antarctic Species: Insights from Weight Loss, XRD, and Thermal Studies

  • Volodymyr Skorokhoda,
  • Ihor Semeniuk,
  • Taras Peretyatko,
  • Viktoria Kochubei,
  • Oleksandr Ivanukh,
  • Yuriy Melnyk and
  • Yurij Stetsyshyn

2 March 2025

This study explores the biodegradation of polyhydroxybutyrate (PHB), polylactide (PLA), and their blends by 11 bacterial species (including Antarctic strains) and 6 fungal species. Aeration significantly enhanced PHB degradation by mold fungi (Asperg...

  • Feature Paper
  • Article
  • Open Access
2 Citations
2,565 Views
14 Pages

Optimized Polyhydroxybutyrate Production by Neobacillus niacini GS1 Utilizing Corn Flour, Wheat Bran, and Peptone: A Sustainable Approach

  • Gaurav Shrimali,
  • Ajit Gangawane,
  • Esha Rami,
  • Hardik Shah,
  • Kashyap Thummar,
  • Dipak Kumar Sahoo,
  • Ashish Patel and
  • Jens Ejbye Schmidt

8 November 2024

Plastic pollution is a pressing environmental challenge, necessitating the development of biodegradable alternatives like polyhydroxybutyrate (PHB). This study focuses on optimizing PHB production by Neobacillus niacini GS1, a bacterium isolated from...

  • Article
  • Open Access
16 Citations
4,740 Views
21 Pages

Characterization and Biotechnological Potential of Intracellular Polyhydroxybutyrate by Stigeoclonium sp. B23 Using Cassava Peel as Carbon Source

  • Murilo Moraes Mourão,
  • Luciana Pereira Xavier,
  • Ralph Urbatzka,
  • Lucas Barbosa Figueiroa,
  • Carlos Emmerson Ferreira da Costa,
  • Carmen Gilda Barroso Tavares Dias,
  • Maria Paula Cruz Schneider,
  • Vitor Vasconcelos and
  • Agenor Valadares Santos

25 February 2021

The possibility of utilizing lignocellulosic agro-industrial waste products such as cassava peel hydrolysate (CPH) as carbon sources for polyhydroxybutyrate (PHB) biosynthesis and characterization by Amazonian microalga Stigeoclonium sp. B23. was inv...

  • Review
  • Open Access
801 Views
35 Pages

Photovoltaic Microorganism Hybrid Systems for Enhanced Polyhydroxybutyrate Synthesis Through Material Design and Energy Mass Transfer Mechanisms

  • Jingyi Teng,
  • Xinyi Chen,
  • Hanyu Gao,
  • Kaixin Huangfu,
  • Silin Wu,
  • Zhuo Ma,
  • Ruiwen Wang,
  • Shaoqin Liu and
  • Yunfeng Qiu

19 December 2025

Polyhydroxybutyrate (PHB), as a biodegradable and green polymer, holds significant potential for replacing traditional petroleum-based plastics. However, its production efficiency and cost remain bottlenecks limiting large-scale application. In recen...

  • Article
  • Open Access
10 Citations
3,208 Views
23 Pages

Toward the Improvement of Maleic Anhydride Functionalization in Polyhydroxybutyrate (PHB): Effect of Styrene Monomer and Sn(Oct)2 Catalyst

  • Matheus Ferreira de Souza,
  • Carlos Bruno Barreto Luna,
  • Danilo Diniz Siqueira,
  • Ewerton de Oliveira Teotônio Bezerra,
  • Grazielle Rozendo de Cerqueira,
  • Edcleide Maria Araújo and
  • Renate Maria Ramos Wellen

22 September 2023

In this work, polyhydroxybutyrate (PHB) was maleic anhydride (MA)-grafted in the molten state, using dicumyl peroxide (DCP) as a reaction initiator. Tin(II) 2-ethylhexanoate (Sn(Oct)2) and styrene monomer (St.) were used to maximize the maleic anhydr...

  • Article
  • Open Access
17 Citations
4,452 Views
20 Pages

The 3D Printability and Mechanical Properties of Polyhydroxybutyrate (PHB) as Additives in Urethane Dimethacrylate (UDMA) Blends Polymer for Medical Application

  • Ahmad Adnan Abu Bakar,
  • Muhammad Zulhilmi Zainuddin,
  • Shahino Mah Abdullah,
  • Nizam Tamchek,
  • Ikhwan Syafiq Mohd Noor,
  • Muhammad Syafiq Alauddin,
  • Ahmad Alforidi and
  • Mohd Ifwat Mohd Ghazali

25 October 2022

The integration of additive manufacturing (3D printing) in the biomedical sector required material to portray a holistic characteristic in terms of printability, biocompatibility, degradability, and mechanical properties. This research aims to evalua...

  • Article
  • Open Access
1 Citations
677 Views
18 Pages

A Polyhydroxybutyrate-Supported Xerogel Biosensor for Rapid BOD Mapping and Integration with Satellite Data for Regional Water Quality Assessment

  • George Gurkin,
  • Alexey Efremov,
  • Irina Koryakina,
  • Roman Perchikov,
  • Anna Kharkova,
  • Anastasia Medvedeva,
  • Bruno Fabiano,
  • Andrea Pietro Reverberi and
  • Vyacheslav Arlyapov

24 October 2025

The growing threat of organic pollution to surface waters necessitates the development of rapid and scalable monitoring tools that transcend the limitations of the standard 5-day biochemical oxygen demand (BOD5) test. This study presents a novel appr...

  • Feature Paper
  • Article
  • Open Access
6 Citations
4,464 Views
20 Pages

27 July 2024

Non-recyclable fiber rejects from paper mills, particularly those from recycled linerboard mills, contain high levels of structural carbohydrates but are currently landfilled, causing financial and environmental burdens. The aim of this study was to...

  • Article
  • Open Access
1 Citations
5,773 Views
10 Pages

6 December 2022

The consumption of methane and the production of biodegradable polymers using alphaproteobacterial methanotrophs offers a promising strategy to mitigate greenhouse gas emissions and reduce non-biodegradable plastic pollution. This study identified an...

  • Article
  • Open Access
3 Citations
2,322 Views
12 Pages

13 November 2024

In this research work, a main biopolymer group of polyhydroxyalkanoates (PHAs) in the form of polyhydroxybutyrate (PHB) was synthesised by a pure bacterial strain of Azotobacter vinelandii via repeated fed-batch fermentation. An agricultural crop, su...

  • Article
  • Open Access
22 Citations
4,762 Views
15 Pages

14 May 2021

With the adverse environmental ramifications of the use of petroleum-based plastic outweighing the challenges facing the industrialization of bioplastics, polyhydroxyalkanoate (PHA) biopolymer has gained broad interest in recent years. Thus, an effic...

  • Article
  • Open Access
5 Citations
2,026 Views
10 Pages

Exploring Schwann Cell Behavior on Electrospun Polyhydroxybutyrate Scaffolds with Varied Pore Sizes and Fiber Thicknesses: Implications for Neural Tissue Engineering

  • María Florencia Lezcano,
  • Paulina Martínez-Rodríguez,
  • Karina Godoy,
  • Jeyson Hermosilla,
  • Francisca Acevedo,
  • Iván Emilio Gareis and
  • Fernando José Dias

6 December 2023

The placement of a polymeric electrospun scaffold is among the most promising strategies to improve nerve regeneration after critical neurotmesis. It is of great interest to investigate the effect of these structures on Schwann cells (SCs), as these...

  • Article
  • Open Access
873 Views
21 Pages

Modulating the Behavior of Schwann Cells with NGF Exposure Combined with Different Energy Densities of Photobiomodulation Cultured on Polyhydroxybutyrate (PHB) Scaffolds

  • Bryan Enoc Quidel-Necul,
  • Paulina Martínez-Rodríguez,
  • Karina Godoy Sanchéz,
  • Glauce Crivelaro Nascimento,
  • Bruna Balbino de Paula,
  • Eduardo Borie and
  • Fernando José Dias

30 October 2025

This study evaluated the effect of irradiation of different energy densities in low-level laser therapy (LLLT) and exogenous nerve growth factor (NGF) on Schwann cells (SCs). SCs (SCL 4.1/F7) exposed to LLLT (4 or 80 J/cm2) and NGF (25 ng/mL) were ev...

  • Article
  • Open Access
2 Citations
2,592 Views
21 Pages

21 April 2023

The aim of this work was to study the valorization of argan seed pulp, a waste material obtained from argan oil extraction, for the biosynthesis of polyhydroxybutyrate (PHB). A new species that showed the metabolic capacity for the conversion of arga...

  • Article
  • Open Access
9 Citations
2,658 Views
15 Pages

Cupriavidus necator-Produced Polyhydroxybutyrate/Eudragit FS Hybrid Nanoparticles Mitigates Ulcerative Colitis via Colon-Targeted Delivery of Cyclosporine A

  • Juho Lee,
  • Aruzhan Saparbayeva,
  • Shwe Phyu Hlaing,
  • Dongmin Kwak,
  • Hyunwoo Kim,
  • Jihyun Kim,
  • Eun Hee Lee and
  • Jin-Wook Yoo

Polyhydroxybutyrate (PHB) has emerged as a novel material for replacing various plastics used in the medical field. However, its application as a drug-delivery carrier for colitis-targeted delivery has not been explored. In this study, we used biosyn...

  • Article
  • Open Access
19 Citations
4,688 Views
19 Pages

Evaluation of Angiogenesis in an Acellular Porous Biomaterial Based on Polyhydroxybutyrate and Chitosan Using the Chicken Ex Ovo Chorioallantoic Membrane Model

  • Zuzana Demcisakova,
  • Lenka Luptakova,
  • Zuzana Tirpakova,
  • Alena Kvasilova,
  • Lubomir Medvecky,
  • Ward De Spiegelaere and
  • Eva Petrovova

30 August 2022

The chorioallantoic membrane (CAM) is a highly vascularized avian extraembryonic membrane widely used as an in vivo model to study angiogenesis and its inhibition in response to tissues, cells, or soluble factors. In recent years, the use of CAM has...

  • Article
  • Open Access
57 Citations
6,048 Views
18 Pages

29 May 2019

Two major obstacles to utilizing polyhydroxybutyrate (PHB)—a biodegradable and biocompatible polymer—in commercial applications are its low tensile yield strength (<10 MPa) and elongation at break (~5%). In this work, we investigated t...

  • Article
  • Open Access
15 Citations
6,122 Views
14 Pages

4 June 2021

The environmental issues caused by the impacts of synthetic plastics use and derived wastes are arising the attention to bio-based plastics, natural polymers produced from renewable resources, including agricultural, industrial, and domestic wastes....

  • Article
  • Open Access
5 Citations
6,358 Views
8 Pages

Microscale Quantitative Analysis of Polyhydroxybutyrate in Prokaryotes Using IDMS

  • Mariana Itzel Velasco Alvarez,
  • Angela Ten Pierick,
  • Patricia T. N. Van Dam,
  • Reza Maleki Seifar,
  • Mark C. M. Van Loosdrecht and
  • S. Aljoscha Wahl

Poly(3-hydroxybutyrate) (PHB) is an interesting biopolymer for replacing petroleum-based plastics, its biological production is performed in natural and engineered microorganisms. Current metabolic engineering approaches rely on high-throughput strai...

  • Article
  • Open Access
3 Citations
2,790 Views
14 Pages

6 January 2021

Polyhydroxybutyrate (PHB) is a bio-based, biodegradable and commercially used polymer, which in its native form is unfortunately not generally applicable. A widely used technique to adapt polymers to a wider range of applications is the surface modif...

of 6