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14 pages, 1502 KiB  
Review
A Bibliographic Analysis of Multi-Risk Assessment Methodologies for Natural Disaster Prevention
by Gilles Grandjean
GeoHazards 2025, 6(3), 41; https://doi.org/10.3390/geohazards6030041 - 1 Aug 2025
Viewed by 153
Abstract
In light of the increasing frequency and intensity of natural phenomena, whether climatic or telluric, the relevance of multi-risk assessment approaches has become an important issue for understanding and estimating the impacts of disasters on complex socioeconomic systems. Two aspects contribute to the [...] Read more.
In light of the increasing frequency and intensity of natural phenomena, whether climatic or telluric, the relevance of multi-risk assessment approaches has become an important issue for understanding and estimating the impacts of disasters on complex socioeconomic systems. Two aspects contribute to the worsening of this situation. First, climate change has heightened the incidence and, in conjunction, the seriousness of geohazards that often occur with each other. Second, the complexity of these impacts on societies is drastically exacerbated by the interconnections between urban areas, industrial sites, power or water networks, and vulnerable ecosystems. In front of the recent research on this problem, and the necessity to figure out the best scientific positioning to address it, we propose, through this review analysis, to revisit existing literature on multi-risk assessment methodologies. By this means, we emphasize the new recent research frameworks able to produce determinant advances. Our selection corpus identifies pertinent scientific publications from various sources, including personal bibliographic databases, but also OpenAlex outputs and Web of Science contents. We evaluated these works from different criteria and key findings, using indicators inspired by the PRISMA bibliometric method. Through this comprehensive analysis of recent advances in multi-risk assessment approaches, we highlight main issues that the scientific community should address in the coming years, we identify the different kinds of geohazards concerned, the way to integrate them in a multi-risk approach, and the characteristics of the presented case studies. The results underscore the urgency of developing robust, adaptable methodologies, effectively able to capture the complexities of multi-risk scenarios. This challenge should be at the basis of the keys and solutions contributing to more resilient socioeconomic systems. Full article
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10 pages, 459 KiB  
Article
Influence of Primary Care Physicians on End-of-Life Treatment Choices in Lung Cancer Diagnosed in the Emergency Department
by Tatsuyuki Kawahara, Nobuaki Ochi, Hirohito Kirishi, Yusuke Sunada, Ayaka Mimura, Naruhiko Ichiyama, Yoko Kosaka, Yasunari Nagasaki, Hidekazu Nakanishi, Hiromichi Yamane and Nagio Takigawa
J. Pers. Med. 2025, 15(8), 339; https://doi.org/10.3390/jpm15080339 - 1 Aug 2025
Viewed by 116
Abstract
Background: Lung cancer remains one of the leading causes of cancer-related mortality worldwide. While most diagnoses occur in outpatient settings, a subset of cases are incidentally identified during emergency department (ED) visits. The clinical characteristics and treatment decisions of these patients, particularly [...] Read more.
Background: Lung cancer remains one of the leading causes of cancer-related mortality worldwide. While most diagnoses occur in outpatient settings, a subset of cases are incidentally identified during emergency department (ED) visits. The clinical characteristics and treatment decisions of these patients, particularly in relation to social background factors such as living situation and access to primary care, remain poorly understood. Methods: We conducted a retrospective study of patients diagnosed with malignancies in the ED of a single institution between April 2018 and December 2021. Patients diagnosed with lung cancer within 60 days of an ED visit were included. Data on demographics, disease status, treatment decisions, and background factors—including whether patients lived alone or had a primary care physician (PCP)—were extracted and analyzed. Results: Among 32,108 patients who visited the ED, 148 were diagnosed with malignancy within 60 days; 23 had lung cancer. Of these, 69.6% had metastatic disease at diagnosis, and 60.9% received active treatment (surgery or chemotherapy). No significant associations were observed between the extent of disease and either living arrangement or PCP status. However, the presence of a PCP was significantly associated with the selection of best supportive care (p = 0.023). No significant difference in treatment decisions was observed based on age (cutoff: 75 years). Conclusions: Although social background factors such as living alone were not significantly associated with cancer stage or treatment choice, the presence of a primary care physician was associated with a higher likelihood of best supportive care being selected. This may indicate that patients with an established PCP have more clearly defined care goals at the end of life. These findings suggest that primary care access may play a role in shaping end-of-life care preferences, highlighting the importance of personalized approaches in acute oncology care. Full article
(This article belongs to the Special Issue New Insights into Personalized Care in Advance Care Planning)
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20 pages, 538 KiB  
Article
Segmenting Preventive Health Behavior: Gender Disparities and Psychosocial Predictors in a Culturally Diverse Italian Region
by Dietmar Ausserhofer, Verena Barbieri, Stefano Lombardo, Timon Gärtner, Klaus Eisendle, Giuliano Piccoliori, Adolf Engl and Christian J. Wiedermann
Eur. J. Investig. Health Psychol. Educ. 2025, 15(8), 148; https://doi.org/10.3390/ejihpe15080148 - 31 Jul 2025
Viewed by 128
Abstract
Grounded in health behavior theory, this study examined patterns of preventive health behavior in a culturally diverse, multilingual region of northern Italy using data from a representative population survey (n = 2090). Preventive behaviors were assessed using the 16-item Good Health Practices [...] Read more.
Grounded in health behavior theory, this study examined patterns of preventive health behavior in a culturally diverse, multilingual region of northern Italy using data from a representative population survey (n = 2090). Preventive behaviors were assessed using the 16-item Good Health Practices (GHP-16) scale. Latent profile analysis (LPA) identified five behavioral profiles, ranging from ‘Globally Low Engagers’ to ‘Comprehensive High Engagers’. Binary logistic regression compared ‘Globally Low Engagers’ to ‘Broadly Moderate Preventers’, examining predictors including gender, age, education, language, chronic disease status, health literacy (HLS-EU-Q16), patient activation (PAM-10), mistrust of health information, living situation, and healthcare employment. The results showed that men, younger adults, individuals with low patient activation, those living alone, and respondents with high mistrust of health information had higher odds of belonging to the low engagement group. Health literacy and language group membership were not significantly associated with the profile membership. Item-level comparisons revealed gender differences in information-seeking, oral hygiene, and dietary behaviors, with men reporting lower engagement. These findings support a segmentation-based understanding of preventive health behavior and highlight the need to address personal capacities and contextual barriers in interventions while challenging assumptions of uniformly higher female health vigilance. Full article
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22 pages, 1119 KiB  
Article
Intergenerational Tacit Knowledge Transfer: Leveraging AI
by Bettina Falckenthal, Manuel Au-Yong-Oliveira and Cláudia Figueiredo
Societies 2025, 15(8), 213; https://doi.org/10.3390/soc15080213 - 31 Jul 2025
Viewed by 251
Abstract
The growing number of senior experts leaving the workforce (especially in more developed economies, such as in Europe), combined with the ubiquitous access to artificial intelligence (AI), is triggering organizations to review their knowledge transfer programs, motivated by both financial and management perspectives. [...] Read more.
The growing number of senior experts leaving the workforce (especially in more developed economies, such as in Europe), combined with the ubiquitous access to artificial intelligence (AI), is triggering organizations to review their knowledge transfer programs, motivated by both financial and management perspectives. Our study aims to contribute to the field by analyzing options to integrate intergenerational tacit knowledge transfer (InterGenTacitKT) with AI-driven approaches, offering a novel perspective on sustainable Knowledge and Human Resource Management in organizations. We will do this by building on previous research and by extracting findings from 36 in-depth semi-structured interviews that provided success factors for junior/senior tandems (JuSeTs) as one notable format of tacit knowledge transfer. We also refer to the literature, in a grounded theory iterative process, analyzing current findings on the use of AI in tacit knowledge transfer and triangulating and critically synthesizing these sources of data. We suggest that adding AI into a tandem situation can facilitate collaboration and thus aid in knowledge transfer and trust-building. We posit that AI can offer strong complementary services for InterGenTacitKT by fostering the identified success factors for JuSeTs (clarity of roles, complementary skill sets, matching personalities, and trust), thus offering organizations a powerful means to enhance the effectiveness and sustainability of InterGenTacitKT that also strengthens employee productivity, satisfaction, and loyalty and overall organizational competitiveness. Full article
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16 pages, 343 KiB  
Article
The Relationship Between Changes in Physical Activity and Physical and Mental Health in Female Breast Cancer Survivors Undergoing Long-Term Activity Restrictions in Japan
by Naomi Tamai, Yasutaka Kimura, Ryuta Yoshizawa and Midori Kamizato
Nurs. Rep. 2025, 15(8), 279; https://doi.org/10.3390/nursrep15080279 - 30 Jul 2025
Viewed by 243
Abstract
Purpose: Exercise is recommended for survivors of breast cancer to alleviate adverse reactions and reduce the psychological burden. In recent years, however, environmental factors (e.g., pandemics and climate change) have made it difficult to exercise outdoors. Therefore, this study focused on the [...] Read more.
Purpose: Exercise is recommended for survivors of breast cancer to alleviate adverse reactions and reduce the psychological burden. In recent years, however, environmental factors (e.g., pandemics and climate change) have made it difficult to exercise outdoors. Therefore, this study focused on the COVID-19 pandemic in Japan and evaluated the relationship between changes in physical activity (PA) and mental and physical health in breast cancer survivors. Methods: A questionnaire survey was conducted among 345 outpatient female breast cancer survivors aged between 29 and 69 years. The questionnaire was based on the International Physical Activity Questionnaire, the Patient Health Questionnaire-9, the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire, and the Fear of COVID-19 Scale and included patient characteristics, changes in PA during pandemic restrictions, and needs for exercise support. The analysis categorized PA changes into two groups according to activity levels. The relationship between changes in PA and physical and mental health was evaluated using logistic regression analysis. Results: Patients with decreased PA accounted for 65.5% of the study population. Regardless of their activity level, these patients were aware of an increased susceptibility to COVID-19, showed a fear of the disease and a tendency for depression, and reported low life satisfaction and declined physical function. Of the patients who stopped exercising, 82.9% reported a decline in PA. Compared with those who had never exercised, those who stopped exercising saw their risk of depression increase by 15.6%. There was a high demand for personalized exercise support from healthcare professionals. Conclusions: Regardless of their activity level, decreasing PA during the pandemic decreased mental health and physical function in breast cancer survivors. There was a higher risk of depression among patients who stopped exercising. Because it is possible that similar situations may occur in the future, interventions by healthcare professionals must be considered in order to continue exercise. Full article
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10 pages, 216 KiB  
Article
Integrating Advance Care Planning into End-of-Life Education: Nursing Students’ Reflections on Advance Health Care Directive and Five Wishes Assignments
by Therese Doan and Sumiyo Brennan
Nurs. Rep. 2025, 15(8), 270; https://doi.org/10.3390/nursrep15080270 - 28 Jul 2025
Viewed by 256
Abstract
Background/Objectives: End-of-life care is a vital part of nursing education that has been overlooked until recent years. Advance care planning should be incorporated into the prelicensure nursing curriculum to build student nurses’ confidence in aiding patients and families with their preferred future [...] Read more.
Background/Objectives: End-of-life care is a vital part of nursing education that has been overlooked until recent years. Advance care planning should be incorporated into the prelicensure nursing curriculum to build student nurses’ confidence in aiding patients and families with their preferred future care plans. Advance care planning tools, such as the Advance Health Care Directive (AHCD) and Five Wishes, provide experiential learning opportunities that bridge theoretical knowledge with real-world patient advocacy. In this study, students were asked to complete either the AHCD or Five Wishes document as though planning for their own end-of-life care, encouraging personal reflection and professional insight. Embedding these assignments into nursing education strengthens students’ confidence in facilitating end-of-life discussions. This study applied Kolb’s experiential learning theory, including concrete experience, reflective observation, abstract conceptualization, and active experimentation, to explore student nurses’ perspectives on the Advance Health Care Directive and Five Wishes assignments, as well as their understanding of end-of-life care. Methods: This study used an exploratory–descriptive qualitative design featuring one open-ended question to collect students’ views on the assignments. Results: The final sample comprised 67 prelicensure student nurses from Bachelor of Science and Entry-Level Master’s programs. The Advance Health Care Directive and/or Five Wishes assignment enhanced students’ understanding of end-of-life decision-making. Conclusions: It is essential to complete the assignment and immerse oneself in an end-of-life situation to grasp patients’ perspectives and concerns regarding when to engage in difficult conversations with their patients. Full article
(This article belongs to the Section Nursing Education and Leadership)
27 pages, 1078 KiB  
Article
Employees’ Entrepreneurial Intention: Multiple Perspectives Challenge the “Common View”
by Leonel Prieto, Muhammad Rofiqul Islam and Md Farid Talukder
Adm. Sci. 2025, 15(8), 293; https://doi.org/10.3390/admsci15080293 - 25 Jul 2025
Viewed by 307
Abstract
Entrepreneurial intention research requires further examination of systemic relationships between constructs of comprehensive models that will more closely approximate the ontological realities of individuals. This research jointly examines relationships among basic individual values and constructs from the theory of planned behavior, entrepreneurial orientation, [...] Read more.
Entrepreneurial intention research requires further examination of systemic relationships between constructs of comprehensive models that will more closely approximate the ontological realities of individuals. This research jointly examines relationships among basic individual values and constructs from the theory of planned behavior, entrepreneurial orientation, and entrepreneurial intention while accounting for multiple contextual factors. Situational factors are accounted for by random determination of mediators, examination of 23 model configurations, and use of quasi-random samples (e.g., respondents with different demographic factors from different organizations, industries, and regions) from two culturally and economically contrasting countries, the United States and India. Models were analyzed using PLS-SEM. Contrary to the “common view”—the idea that Western countries are individualistic and Asian and Latin American countries are collectivistic—individual personal focus values and passion relationships were stronger for India’s sample than for the United States. Contrary results were found for basic individual social focus values and subjective norms relationships. Results show a lack of stark disparities between the two country samples. Hence, it seems that between-country differences have been overemphasized, while more attention to context and to within-country variability is required. This study expands the entrepreneurial orientation nomological network by jointly considering basic individual values and TPB’s and EO’s constructs anteceding entrepreneurial intention and examining a large set of model configurations while accounting for multiple situational factors in two culturally and economically contrasting countries. Full article
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20 pages, 255 KiB  
Article
The Bonaventurian Synthesis of the Human Being as “Imago et Similitudo Dei”: The Existential Realisation of a Person as a “Seeker of Truth” and a “Wayfarer Summoned by Love”
by Francisco Javier Rubio Hípola
Religions 2025, 16(8), 963; https://doi.org/10.3390/rel16080963 - 25 Jul 2025
Viewed by 250
Abstract
This study explores the Bonaventurian synthesis of the human being as imago et similitudo Dei, highlighting its anthropological and existential implications. Against the backdrop of contemporary reductionist approaches that fragment the understanding of the human person, Bonaventure offers a holistic vision that integrates [...] Read more.
This study explores the Bonaventurian synthesis of the human being as imago et similitudo Dei, highlighting its anthropological and existential implications. Against the backdrop of contemporary reductionist approaches that fragment the understanding of the human person, Bonaventure offers a holistic vision that integrates intellectual, affective, and volitional dimensions within a Christocentric and Trinitarian framework. Through a systematic analysis of Bonaventure’s primary texts—particularly the Itinerarium mentis in Deum and the Collationes in Hexaëmeron—and supported by critical scholarship, the article argues that human fulfillment transcends the limits of pure rationality and culminates in the unitive act of love with God. The study identifies two central principles of what Lázaro Pulido calls “Christian Socratism”: (1) human life as a journey to the Father’s house, and (2) the configuration of the soul, in wisdom and love, as a dwelling place of God. By situating the moral and spiritual life within the logic of divine attraction, Bonaventure overcomes both Aristotelian intellectualism and postmodern individualism. Ultimately, his thought presents happiness not as self-realization but as conformity with Christ crucified, revealing a path where suffering acquires meaning and the human vocation to love finds its ultimate horizon in the Trinity. Full article
22 pages, 916 KiB  
Article
A Model Based on Variable Weight Theory and Interval Grey Clustering to Evaluate the Competency of BIM Construction Engineers
by Shaonan Sun, Yiming Zuo, Chunlu Liu, Xiaoxiao Yao, Ailing Wang and Zhihui Wang
Buildings 2025, 15(14), 2574; https://doi.org/10.3390/buildings15142574 - 21 Jul 2025
Viewed by 171
Abstract
Building information modeling (BIM) has emerged as a fundamental component of Industry 4.0 recently. BIM construction engineers (BCEs) play a pivotal role in implementing BIM, and their personal competency is crucial to the successful application and promotion of BIM technology. Existing research on [...] Read more.
Building information modeling (BIM) has emerged as a fundamental component of Industry 4.0 recently. BIM construction engineers (BCEs) play a pivotal role in implementing BIM, and their personal competency is crucial to the successful application and promotion of BIM technology. Existing research on evaluating BIM capabilities has mainly focused on the enterprise or project level, neglecting individual-level analysis. Therefore, this study aims to establish an individual-level competency evaluation model for BCEs. Firstly, the competency of BCEs was divided into five levels by referring to relevant standards and domestic and foreign research. Secondly, through the analysis of literature data and website data, the competency evaluation indicator system for BCEs was constructed, which includes four primary indicators and 27 secondary indicators. Thirdly, variable weight theory was used to optimize the weights determined by general methods and calculate the comprehensive weights of each indicator. Then the competency levels of BCEs were determined by the interval grey clustering method. To demonstrate the application of the proposed method, a case study from a Chinese enterprise was conducted. The main results derived from this case study are as follows: domain competencies have the greatest weight among the primary indicators; the C9-BIM model is the secondary indicator with the highest weight (ωj = 0.0804); and the competency level of the BCE is “Level 3”. These results are consistent with the actual situation of the enterprise. The proposed model in this study provides a comprehensive tool for evaluating BCEs’ competencies from an individual perspective, and offers guideline for BCEs to enhance their competencies in pursuing sustainable professional development. Full article
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15 pages, 1019 KiB  
Article
Micro-Yizkor and Hasidic Memory: A Post-Holocaust Letter from the Margins
by Isaac Hershkowitz
Religions 2025, 16(7), 937; https://doi.org/10.3390/rel16070937 - 19 Jul 2025
Viewed by 496
Abstract
This paper examines a previously unknown anonymous Hebrew letter inserted into a postwar edition of Shem HaGedolim, found in the library of the Jewish University in Budapest. The letter, composed in Győr in 1947, consists almost entirely of passages copied from Tiferet Chayim, [...] Read more.
This paper examines a previously unknown anonymous Hebrew letter inserted into a postwar edition of Shem HaGedolim, found in the library of the Jewish University in Budapest. The letter, composed in Győr in 1947, consists almost entirely of passages copied from Tiferet Chayim, a hagiographic genealogy of the Sanz Hasidic dynasty. Although derivative in content, the letter’s form and placement suggest it was not meant for transmission but instead served as a private act of mourning and historiographical preservation. By situating the letter within the broader context of post-Holocaust Jewish and Hasidic memory practices, including yizkor books, rabbinic memoirs, and grassroots commemorative writing, this study proposes that the document constitutes a “micro-yizkor”: a bibliographic ritual that aimed to re-inscribe lost tzaddikim into sacred memory. Drawing on theories of trauma, religious coping, and bereavement psychology, particularly the Two-Track Model of Bereavement, the paper examines the letter as both a therapeutic and historiographical gesture. The author’s meticulous copying, selective omissions, and personalized touches (such as modified honorifics and emotive phrases) reflect an attempt to maintain spiritual continuity in the wake of communal devastation. Engaging scholarship by Michal Shaul, Lior Becker, Gershon Greenberg, and others, the analysis demonstrates how citation, far from being a passive act, functions here as an instrument of resistance, memory, and redemptive reconstruction. The existence of such a document can also be examined through the lens of Maurice Rickards’ insights, particularly his characterization of the “compulsive note” as a salient form of ephemera, materials often inserted between the pages of books, which pose unique challenges for interpreting the time capsule their authors sought to construct. Ultimately, the paper argues that this modest and anonymous document offers a rare window into postwar Ultra-orthodox religious subjectivity. It challenges prevailing assumptions about Hasidic silence after the Holocaust and demonstarates how even derivative texts can serve as potent sites of historical testimony, spiritual resilience, and bibliographic mourning. The letter thus sheds light on a neglected form of Hasidic historiography, one authored not by professional historians, but by the broken-hearted, writing in the margins of sacred books. Full article
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11 pages, 305 KiB  
Article
Teachers’ Perspectives on the Impact of an Outdoor-Based Self-Care Training Program on Student Mental Health
by Katie A. Bucher, Connor M. Moriarty, Adam Lazarchak and Russell K. McIntire
Int. J. Environ. Res. Public Health 2025, 22(7), 1135; https://doi.org/10.3390/ijerph22071135 - 18 Jul 2025
Viewed by 474
Abstract
As mental health disorders in the U.S. increase at an alarming rate, schools are looking for prevention and mitigation interventions for their students. This study reports teachers’ perspectives on the effectiveness of a school program situated at the intersection of self-care and nature-based [...] Read more.
As mental health disorders in the U.S. increase at an alarming rate, schools are looking for prevention and mitigation interventions for their students. This study reports teachers’ perspectives on the effectiveness of a school program situated at the intersection of self-care and nature-based interventions at a vocational technical high school. Eight classes received between one and four “Intro to Well-Being” sessions, designed to take students outside and develop self-awareness, sense of connection, and reduce stress. Upon the conclusion of the program, classroom teachers were interviewed to identify the perceptions of the sessions and their impact on student and classroom outcomes. Teachers described the sessions as beneficial to students’ expression of emotions, mindfulness skills, personal/social connections, and classroom atmosphere. Teachers also reflected on challenges and provided recommendations for future implementation. Outdoor-based self-care programs, administered at schools, may be a promising program model to support the social and emotional health of students. Full article
(This article belongs to the Special Issue Mental Health and Wellbeing of Children and Adolescents)
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24 pages, 327 KiB  
Article
Pope Francis’s Communication Strategies During His Middle East Pilgrimages: An Analysis of Interreligious Discourse and Pontifical Diplomacy
by Aldona Maria Piwko
Religions 2025, 16(7), 917; https://doi.org/10.3390/rel16070917 - 16 Jul 2025
Viewed by 405
Abstract
This article examines the communication strategies of religious diplomacy used by Pope Francis in his diplomatic relations with the countries of the Middle East from 2013 to 2025. The study identifies and characterizes key elements of papal communication, taking into account both verbal [...] Read more.
This article examines the communication strategies of religious diplomacy used by Pope Francis in his diplomatic relations with the countries of the Middle East from 2013 to 2025. The study identifies and characterizes key elements of papal communication, taking into account both verbal and nonverbal dimensions, in the context of the complex geopolitical and religious situation of the region. Based on the analysis of official documents, speeches, foreign visits and diplomatic initiatives, specific communication patterns are identified that distinguish Francis’ pontificate from that of his predecessors. The research results indicate an innovative approach of the Pope, combining traditional Vatican diplomacy with direct personal engagement, the use of symbolism of gestures and the promotion of interreligious dialogue as a tool for building peace and intercultural understanding. Full article
17 pages, 398 KiB  
Article
Turning Setbacks into Smiles: Exploring the Role of Self-Mocking Strategies in Consumers’ Recovery Satisfaction After E-Commerce Service Failures
by Yali Zhang, Jiale Huang and Qiwei Pang
J. Theor. Appl. Electron. Commer. Res. 2025, 20(3), 183; https://doi.org/10.3390/jtaer20030183 - 16 Jul 2025
Viewed by 406
Abstract
In today’s competitive environment of online service industries, particularly e-commerce, meeting consumer expectations is essential for service providers to ensure service quality. However, service failures are unavoidable, leading to unfavorable consequences for businesses. Understanding the mechanisms for customer recovery after negative service experiences [...] Read more.
In today’s competitive environment of online service industries, particularly e-commerce, meeting consumer expectations is essential for service providers to ensure service quality. However, service failures are unavoidable, leading to unfavorable consequences for businesses. Understanding the mechanisms for customer recovery after negative service experiences is crucial. Using cognitive–emotional personality systems theory and benign violation theory, this study constructed a theoretical model. A total of 351 samples were collected through a situational simulation experiment for a linear regression analysis. A self-mocking response strategy positively influenced brand trust through perceived brand authenticity regarding the dimensions of credibility, integrity, and symbolism. Simultaneously, brand trust was identified as a key driver of post-recovery satisfaction. This study proposes a chain mediation model, which incorporates perceived authenticity and brand trust, to fully comprehend the mechanisms underlying consumers’ satisfaction after service recovery. Our findings provide empirical evidence for the effects of self-mockery on post-recovery satisfaction, as well as suggestions for marketers seeking efficient means to meet consumers’ emotional and cognitive demands during service recovery situations. Full article
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26 pages, 2695 KiB  
Review
Bioactive Compounds as Modulators of N-Formyl Peptide Signaling in Chronic Diseases
by Livia Alvarenga, Ludmila F. M. F. Cardozo, Márcia Ribeiro, Fernanda Kussi, Marta Esgalhado and Denise Mafra
Molecules 2025, 30(14), 2981; https://doi.org/10.3390/molecules30142981 - 16 Jul 2025
Viewed by 478
Abstract
In physiological situations involving cell damage, molecules derived from mitochondria or bacteria are produced. These molecules are known as N-formyl peptides and are detected by formyl peptide receptors (FPRs), which stimulate immune cells to migrate to the specific site of injury or infection. [...] Read more.
In physiological situations involving cell damage, molecules derived from mitochondria or bacteria are produced. These molecules are known as N-formyl peptides and are detected by formyl peptide receptors (FPRs), which stimulate immune cells to migrate to the specific site of injury or infection. Despite their initially beneficial effects on health, N-formyl peptides also contribute to the development or exacerbation of chronic non-communicable diseases. Therefore, understanding the metabolic pathways related to the involvement of N-formyl peptides and FPRs may increase our ability to regulate immune responses and precisely target FPRs with personalized strategies, offering a promising approach for the treatment of specific diseases. In this way, bioactive compounds in food may influence N-formyl peptides, interacting with the receptors either competitively or by inhibiting them, which affects the inflammatory response and oxidative reactions of cells. This review examines the pathways associated with forming N-formyl peptides, the activation of FPRs, and the roles of bioactive compounds in regulating N-formyl peptides. Full article
(This article belongs to the Special Issue Exploring Bioactive Compounds in Foods and Nutrients for Human Health)
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22 pages, 1199 KiB  
Article
Less Is More: Analyzing Text Abstraction Levels for Gender and Age Recognition Across Question-Answering Communities
by Alejandro Figueroa
Information 2025, 16(7), 602; https://doi.org/10.3390/info16070602 - 13 Jul 2025
Viewed by 182
Abstract
In social networks like community Question-Answering (cQA) services, members interact with each other by asking and answering each other’s questions. This way they find counsel and solutions to very specific real-life situations. Thus, it is safe to say that community fellows log into [...] Read more.
In social networks like community Question-Answering (cQA) services, members interact with each other by asking and answering each other’s questions. This way they find counsel and solutions to very specific real-life situations. Thus, it is safe to say that community fellows log into this kind of social network with the goal of satisfying information needs that cannot be readily resolved via traditional web searches. And in order to expedite this process, these platforms also allow registered, and many times unregistered, internauts to browse their archives. As a means of encouraging fruitful interactions, these websites need to be efficient when displaying contextualized/personalized material and when connecting unresolved questions to people willing to help. Here, demographic factors (i.e., gender) together with frontier deep neural networks have proved to be instrumental in adequately overcoming these challenges. In fact, current approaches have demonstrated that it is perfectly plausible to achieve high gender classification rates by inspecting profile images or textual interactions. This work advances this body of knowledge by leveraging lexicalized dependency paths to control the level of abstraction across texts. Our qualitative results suggest that cost-efficient approaches exploit distilled frontier deep architectures (i.e., DistillRoBERTa) and coarse-grained semantic information embodied in the first three levels of the respective dependency tree. Our outcomes also indicate that relative/prepositional clauses conveying geographical locations, relationships, and finance yield a marginal contribution when they show up deep in dependency trees. Full article
(This article belongs to the Section Information Applications)
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