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  • Article
  • Open Access
13 Citations
4,024 Views
11 Pages

Endo-Periodontal Lesions—An Overlooked Etiology of Odontogenic Sinusitis

  • Jianyou Wu,
  • Ming Zheng,
  • Xiangdong Wang and
  • Songlin Wang

31 October 2023

The aim of this study was to analyze the oral etiology of patients with odontogenic sinusitis (ODS) and to compare the differences in demographic data, clinical symptoms, extent of sinus involvement, bone penetration of the maxillary sinus floor (MSF...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Article
  • Open Access
9 Citations
3,685 Views
11 Pages

The Influence of Endodontic Lesions on The Clinical Evolution of Odontogenic Sinusitis—A Cohort Study

  • Marta Aleksandra Kwiatkowska,
  • Kornel Szczygielski,
  • Agnieszka Brociek-Piłczyńska,
  • Aldona Chloupek and
  • Dariusz Jurkiewicz

31 January 2023

Endodontic disease with formation of periapical lesions (PALs) is one of the most common causes of chronic odontogenic sinusitis (ODS). It requires close collaboration between otolaryngologists and dentists, but the best sequence of management is sti...

(This article belongs to the Special Issue Advances in Treatment and Management of Chronic Rhinosinusitis)
  • Article
  • Open Access
653 Views
19 Pages

Quantitative PCR-Based Analysis of Bacterial Profiles in Periapical Lesions and Maxillary Sinus in Odontogenic Sinusitis

  • Marta Aleksandra Kwiatkowska,
  • Alicja Trębińska-Stryjewska,
  • Katarzyna Andrejuk,
  • Dariusz Jurkiewicz,
  • Elżbieta Anna Trafny and
  • Aneta Guzek

Odontogenic sinusitis (ODS) is a common cause of unilateral maxillary sinusitis arising from periapical lesions (PALs) or other dental sources. The infection is typically polymicrobial and dominated by anaerobic bacteria, which are often under detect...

(This article belongs to the Section Molecular Microbiology)
  • Article
  • Open Access
4 Citations
2,344 Views
14 Pages

Status of Microbiota in Odontogenic Inflammatory Lesions and Dental Surgery Procedures Performed on an Outpatient Basis

  • Tadeusz Morawiec,
  • Joanna Śmieszek-Wilczewska,
  • Mateusz Bogacz,
  • Magdalena Jędrusik-Pawłowska,
  • Anna Bubiłek-Bogacz and
  • Anna Mertas

Inflammations of the facial part of the skull are most commonly caused by a bacterial infection. They are a frequently occurring pathological process, which results from a rich bacterial flora of the oral cavity, as well as diseased teeth and periodo...

(This article belongs to the Section Antibiotic Therapy in Infectious Diseases)
  • Case Report
  • Open Access
2 Citations
1,146 Views
13 Pages

Diagnostic Pitfalls of Dental Follicles and Cyst-like Lesions in Juvenile Patients: An Early Odontogenic Myxoma Mimicking a Follicular Cyst

  • Kamil Nelke,
  • Klaudiusz Łuczak,
  • Michał Gontarz,
  • Grażyna Wyszyńska-Pawelec,
  • Agata Małyszek,
  • Ömer Uranbey,
  • Dayel Gerardo Rosales Díaz Mirón,
  • Maciej Dobrzyński,
  • Małgorzata Tarnowska and
  • Piotr Kuropka

12 January 2026

The occurrence of cysts and tumors in pediatric patients varies across different age groups. Follicular and dentigerous cysts are among the most common lesions. However, typical odontogenic tumors in juvenile patients are not frequently observed. Ear...

(This article belongs to the Special Issue Clinical Challenges and Advances in Periodontology and Oral Surgery: 2nd Edition)
  • Case Report
  • Open Access
1 Citations
1,381 Views
19 Pages

Odontogenic Infection Associated with Facial Vascular Malformation: Diagnostic, Surgical, and Quality-of-Life Considerations That Should Not Be Overlooked

  • Kamil Nelke,
  • Klaudiusz Łuczak,
  • Michał Gontarz,
  • Angela Rosa Caso,
  • Maciej Janeczek,
  • Ömer Uranbey,
  • Dayel Gerardo Rosales Díaz Mirón,
  • Maciej Dobrzyński,
  • Małgorzata Tarnowska and
  • Piotr Kuropka

3 April 2026

Background and Clinical Significance: Vascular lesions of the face, particularly arteriovenous malformations (AVM) and mixed hemangiomas (MH), pose significant diagnostic and therapeutic challenges because of their complex anatomy, unpredictable beha...

(This article belongs to the Special Issue Current Challenges in Oral and Maxillofacial Surgery)
  • Article
  • Open Access
10 Citations
7,885 Views
13 Pages

Association between Maxillary Posterior Teeth Periapical Odontogenic Lesions and Maxillary Sinus Mucosal Thickening: A 3D Volumetric Computed Tomography Analysis

  • Regimantas Simuntis,
  • Paulius Tušas,
  • Ričardas Kubilius,
  • Marijus Leketas,
  • Nora Šiupšinskienė and
  • Saulius Vaitkus

2 December 2020

Background: The detailed relationship between apical periodontitis and maxillary sinus mucosal thickening is still unknown. The aim of this study was to evaluate the association between maxillary posterior teeth periapical odontogenic lesions and max...

  • Article
  • Open Access
1 Citations
631 Views
16 Pages

Microbiological PCR Characteristics of Odontogenic Sinusitis and Their Clinical Correlates: A Cross-Sectional Analysis

  • Marta Aleksandra Kwiatkowska,
  • Alicja Trębińska-Stryjewska,
  • Dariusz Jurkiewicz and
  • Elżbieta Anna Trafny

27 February 2026

Background: Odontogenic sinusitis (ODS) represents a distinct form of maxillary sinus inflammation arising from dental pathology and is most commonly unilateral. Despite its polymicrobial nature and predominance of anaerobic organisms, molecular char...

(This article belongs to the Section Otolaryngology)
  • Article
  • Open Access
1 Citations
3,738 Views
9 Pages

Curved Planar Reformation: A Useful Method for Screening Dental Pathologies in Chronic Rhinosinusitis via Paranasal Sinus Computed Tomography

  • Wei-Chih Chen,
  • Lisa Alice Hwang,
  • Wei-Che Lin,
  • Ching-Nung Wu,
  • Wei-Chia Su,
  • Kuan-Chung Fang and
  • Sheng-Dean Luo

16 September 2022

(1) Background: Curved planar reformation (CPR) is a multiplanar reformatting technique of computed tomography (CT) commonly used during dental cone-beam CT (CBCT) to generate panorex-like images for dental evaluation. Here, we evaluated the utility...

  • Article
  • Open Access
785 Views
11 Pages

Deep Learning-Assisted Localization of Cystic Lesions and Benign Tumors in the Maxillofacial Region Using Panoramic Radiographs: A Preliminary Feasibility Study

  • Kai-Hua Lien,
  • Sih-Yi Wu,
  • Yun-Ya Yang,
  • Jia-Yu Liu,
  • Yi-Cheng Chen,
  • Ten-Yi Huang,
  • Yu-Wen Tang,
  • Yen-Chu Hsiao,
  • Chung-Bin Wu and
  • Cheng-Chia Yu

7 April 2026

Background/Objectives: Automated localization of cystic lesions and benign tumors on panoramic radiographs may support lesion recognition in the maxillofacial region. This preliminary feasibility study aimed to develop and evaluate a deep learning mo...

(This article belongs to the Special Issue Artificial Intelligence (AI) in Dental Clinical Practice)
  • Article
  • Open Access
20 Citations
5,265 Views
15 Pages

Association between Cone-Beam Computed Tomography and Histological and Immunohistochemical Features in Periapical Lesions Correlated with Thickened Maxillary Sinus Mucosa

  • Alexandra Dumitrescu,
  • Maria-Alexandra Martu,
  • Alexandru Nemtoi,
  • Ana Sirghe,
  • Liliana Chelaru,
  • Diana Tatarciuc,
  • Ana-Maria Dumitrescu and
  • Danisia Haba

19 August 2021

Background and Objectives: Odontogenic sinusitis is a frequently underestimated pathology with fewer symptoms in patients with periapical lesions, periodontal disease, or iatrogenic foreign bodies in the maxillary sinus. The aim of our study was to d...

(This article belongs to the Collection New Concepts for Dental Treatments and Evaluations)
  • Case Report
  • Open Access
12 Citations
3,260 Views
10 Pages

15 November 2021

(1) Surgical intervention becomes crucial in situations in which lack of action would cause a decrease in quality of life for the patient. As healthcare professionals, our next objective is to reduce patient fear perception. This work’s aim is...

(This article belongs to the Special Issue Feature Papers in Dentistry Journal in 2021)
  • Review
  • Open Access
2 Citations
5,657 Views
17 Pages

15 July 2022

Tooth eruption disturbances associated with developmental odontogenic cysts represent a particular challenge in orthodontic treatment. Early diagnosis, crucial for prompt and effective therapy, is possible with a thorough radiological analysis. Three...

(This article belongs to the Special Issue Clinical Applications in Orthodontic)
  • Case Report
  • Open Access
2 Citations
8,133 Views
14 Pages

Ameloblastoma in a Three-Year-Old Child with Hurler Syndrome (Mucopolysaccharidosis Type I)

  • Mattia Di Bartolomeo,
  • Arrigo Pellacani,
  • Sara Negrello,
  • Martina Buchignani,
  • Riccardo Nocini,
  • Gianluca Di Massa,
  • Greta Gianotti,
  • Giuseppe Pollastri,
  • Giacomo Colletti and
  • Alexandre Anesi
  • + 1 author

15 March 2022

Mucopolysaccharidoses (MPS) are a family of genetic diseases associated with a deficiency of alpha-L iduronidase, which causes a lack of catabolism of glycosaminoglycans (GAGs). Therefore, the accumulation of GAGs determines a wide spectrum of sympto...

  • Systematic Review
  • Open Access
3 Citations
6,617 Views
76 Pages

Objective: This systematic review investigates the diagnostic, prognostic, and therapeutic implications of immunohistochemical markers in dentigerous cysts (DCs) and odontogenic keratocysts (OKCs) associated with impacted third molars. Materials and...

(This article belongs to the Special Issue Advances in the Diagnosis of Oral and Maxillofacial Disease)
  • Case Report
  • Open Access
4,325 Views
8 Pages

Dentinogenic Ghost Cell Tumor in a Sumatran Rhinoceros

  • Annas Salleh,
  • Zainal Z. Zainuddin,
  • Reza M. M. Tarmizi,
  • Chee K. Yap,
  • Chian-Ren Jeng and
  • Mohd Zamri-Saad

20 April 2021

An adult female Sumatran rhinoceros was observed with a swelling in the left infraorbital region in March 2017. The swelling rapidly grew into a mass. A radiograph revealed a cystic radiolucent area in the left maxilla. In June 2017, the rhinoceros w...

(This article belongs to the Special Issue Comparative Pathology and Immunohistochemistry of Veterinary Species)
  • Article
  • Open Access
1 Citations
3,009 Views
14 Pages

Extent of Endoscopic Sinus Surgery for Odontogenic Sinusitis of Endodontic Origin with Ethmoid and Frontal Sinus Involvement

  • Marta Aleksandra Kwiatkowska,
  • Kornel Szczygielski,
  • Dariusz Jurkiewicz and
  • Piotr Rot

18 October 2024

Background/Objectives: Odontogenic sinusitis (ODS) is the most common cause of unilateral maxillary sinus opacification. Initial treatment consists of intranasal steroids and antimicrobial therapy. In case of persistence of the disease, endoscopic si...

(This article belongs to the Special Issue Chronic Rhinosinusitis: Advances in Diagnosis, Management and Patient Experience)
  • Article
  • Open Access
1 Citations
805 Views
19 Pages

Radiomics in the Evaluation of Cystic and Neoplastic Lytic Lesions of the Jaws

  • Paola Di Giacomo,
  • Pasquale Frisina,
  • Alberto Fratocchi,
  • Pierluigi Barra,
  • Cira Rosaria Tiziana Di Gioia,
  • Flavia Adotti,
  • Giovanni Falisi,
  • Fabrizio Spallaccia,
  • Iole Vozza and
  • Daniela Messineo
  • + 2 authors

Background/Objectives. Radiomics is an emerging imaging-based tool that enhances lesion characterization beyond conventional diagnostic approaches. Its potential in evaluating osteolytic lesions of the jaws lies in improving discrimination between be...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
4 Citations
2,100 Views
13 Pages

Microbiological Comparison of Maxillary Sinus Rinses in Non-Odontogenic and Odontogenic Sinusitis of Primarily Endodontic Origin

  • Marta Aleksandra Kwiatkowska,
  • Aneta Guzek,
  • Dariusz Jurkiewicz,
  • Iwona Patyk,
  • Barbara Pajda and
  • Piotr Rot

9 July 2025

Objectives: Odontogenic sinusitis (ODS) is common but frequently overlooked condition that differs from rhinogenic sinusitis (CRS) and should be suspected in each case of unilateral sinusitis. Clinical symptoms such as foul smell, congestion, rhinorr...

(This article belongs to the Section Otolaryngology)
  • Article
  • Open Access
7 Citations
10,023 Views
13 Pages

Dentigerous Cysts in Children: Clinical, Radiological, and Healing Aspects

  • Maria Cristina Langă,
  • Diana Florina Nica,
  • Virgil-Florin Duma,
  • Rodica Elena Heredea and
  • Cosmin Sinescu

14 July 2024

Background and Objectives: Dentigerous cysts are one of the most frequent pathologies associated with unerupted or impacted teeth. Such cysts show a male predilection and a preference for the mandibular region. Also, they commonly occur in the second...

(This article belongs to the Collection New Concepts for Dental Treatments and Evaluations)
  • Feature Paper
  • Article
  • Open Access
7 Citations
6,280 Views
8 Pages

A Comparative Statistical Analysis on the Incidence of Developmental, Inflammatory and Neoplastic Odontogenic Cysts—A Single Center Retrospective Analysis from Italy

  • Antonio Barresi,
  • Giacomo Oteri,
  • Angela Alibrandi,
  • Matteo Peditto,
  • Silvia Rapisarda,
  • Roberta Cardia,
  • Antonia Marcianò and
  • Maria Lentini

21 January 2021

The aim of this study was a comparative statistical analysis of three categories of maxillary odontogenic cysts, evaluating frequency in relation to localization (mandibular or maxillary region), age and gender of patients. The study was a retrospect...

  • Article
  • Open Access
23 Citations
5,961 Views
14 Pages

Emulating Clinical Diagnostic Reasoning for Jaw Cysts with Machine Learning

  • Balazs Feher,
  • Ulrike Kuchler,
  • Falk Schwendicke,
  • Lisa Schneider,
  • Jose Eduardo Cejudo Grano de Oro,
  • Tong Xi,
  • Shankeeth Vinayahalingam,
  • Tzu-Ming Harry Hsu,
  • Janet Brinz and
  • Joachim Krois
  • + 9 authors

The detection and classification of cystic lesions of the jaw is of high clinical relevance and represents a topic of interest in medical artificial intelligence research. The human clinical diagnostic reasoning process uses contextual information, i...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Case Report
  • Open Access
5 Citations
1,703 Views
5 Pages

22 June 2020

Odontogenic keratocyst (OKC) and ameloblastomas are distinct histopathologically diagnosed odontogenic lesions of the oral cavity. Both are primarily located in the posterior regions of the mandible, however, they can involve the maxilla as well. The...

  • Interesting Images
  • Open Access
2 Citations
10,645 Views
6 Pages

Gingival Cyst of the Adult: A Case Description with a Relevant Literature Analysis

  • Marta Forte,
  • Antonio d’Amati,
  • Alfonso Manfuso,
  • Massimiliano Vittoli,
  • Giorgia Girone,
  • Eliano Cascardi and
  • Saverio Capodiferro

24 June 2024

Gingival cysts of the adult are rare and benign odontogenic lesions of the oral cavity, accounting for almost 0.3% of all odontogenic cysts. Their differential diagnosis is still challenging for surgeons as it includes other gingival inflammatory or...

(This article belongs to the Special Issue Clinical Research on Oral Diseases)
  • Case Report
  • Open Access

Primordial Odontogenic Tumor of the Maxilla Mimicking Odontogenic Myxoma in a Child: A Case Report and Review of the Literature

  • Zuzanna Katarzyna Sokołowska,
  • Dawid Rahimi,
  • Maria Magdalena Szwajkowska,
  • Maciej Borowiec,
  • Aleksandra Sejda,
  • Łukasz Krakowczyk and
  • Krzysztof Dowgierd

13 October 2026

Introduction: Primordial odontogenic tumor (POT) is an exceptionally rare benign mixed odontogenic neoplasm recognized as a distinct entity in the 2017 World Health Organization classification of head and neck tumors. Owing to its rarity and overlapp...

  • Interesting Images
  • Open Access
1,596 Views
12 Pages

“Dry Tap” Fine-Needle Aspiration Biopsy as a Diagnostic Clue in Cyst-like Juvenile Jaw Lesions Mimicking Dentigerous Cysts on Panoramic Radiography and Cone-Beam Computed Tomography

  • Kamil Nelke,
  • Klaudiusz Łuczak,
  • Ömer Uranbey,
  • Büşra Ekinci,
  • Angela Rosa Caso,
  • Michał Gontarz,
  • Maciej Janeczek,
  • Zygmunt Stopa,
  • Piotr Kuropka and
  • Maciej Dobrzyński

Pediatric odontogenic tumors are rare but are frequently overlooked because they often mimic simple cysts on routine radiographic examinations. The radiographic appearance on panoramic imaging and cone-beam computed tomography (CBCT) frequently does...

(This article belongs to the Special Issue Pathology and Diagnosis of Head and Neck Diseases)
  • Review
  • Open Access
7 Citations
4,697 Views
21 Pages

The Stem Cell Expression Profile of Odontogenic Tumors and Cysts: A Systematic Review and Meta-Analysis

  • Eleni-Marina Kalogirou,
  • Georgios Lekakis,
  • Aristodimos Petroulias,
  • Konstantinos Chavdoulas,
  • Vasileios L. Zogopoulos,
  • Ioannis Michalopoulos and
  • Konstantinos I. Tosios

30 August 2023

Background: Stem cells have been associated with self-renewing and plasticity and have been investigated in various odontogenic lesions in association with their pathogenesis and biological behavior. We aim to provide a systematic review of stem cell...

(This article belongs to the Section Molecular Genetics and Genomics)
  • Case Report
  • Open Access
1,423 Views
10 Pages

Surgical Treatment of Maxillary Odontogenic Myxoma with Conservative Enucleation and Curettage: A Case Report

  • Oscar Arturo Benítez-Cárdenas,
  • Elhi Manuel Torres-Hernández,
  • Miguel Angel Noyola-Frías,
  • Ricardo Martínez-Rider and
  • Marlen Vitales-Noyola

3 July 2026

Background and Clinical Significance: Odontogenic myxoma (OM) is a rare benign neoplasm of the jawbones characterized by spindle-shaped cells embedded in a myxoid stroma. Despite its benign histological nature, it demonstrates locally aggressive beha...

  • Article
  • Open Access
6 Citations
5,052 Views
11 Pages

Benign Pediatric Jawbone Lesions: A 10-Year Clinical and Radiological Pilot Study

  • Emil Crasnean,
  • Alina Ban,
  • Mihaela Hedeșiu,
  • Raluca Roman,
  • Cristian Dinu,
  • Mihaela Băciuț,
  • Sergiu Văcăraș,
  • Ileana Mitre,
  • Oana Almășan and
  • Florin Onișor
  • + 3 authors

9 February 2023

This study aimed at presenting a retrospective longitudinal analysis of the pediatric jaw lesions treated at the Oral and Maxillofacial Surgery Clinic in Cluj-Napoca, Romania, over a timeframe of ten years (2012 to 2022). The clinical and radiologica...

(This article belongs to the Special Issue 10th Anniversary of Children: Pediatric Dentistry Progress)
  • Extended Abstract
  • Open Access
1 Citations
1,557 Views
3 Pages

Odontogenic Cysts: A 30-Year Retrospective Clinicopathological Study

  • Marco Mascitti,
  • Lucrezia Togni,
  • Lorenzo Lo Muzio,
  • Giuseppina Campisi,
  • Federico Mazzoni and
  • Andrea Santarelli

Odontogenic cysts (OC) are one of the most frequent lesions. [...]

(This article belongs to the Proceedings of The XV National and III International Congress of the Italian Society of Oral Pathology and Medicine)
  • Interesting Images
  • Open Access
417 Views
13 Pages

Odontogenic Sinusitis: The Selective Role of a Modified Caldwell–Luc Approach in Two CT/CBCT-Documented Cases

  • Kamil Nelke,
  • Suat Aktaş,
  • Ömer Uranbey,
  • Marceli Łukaszewski,
  • India Maag,
  • Maciej Janeczek,
  • Agata Małyszek,
  • Michał Gontarz,
  • Klaudiusz Łuczak and
  • Maciej Dobrzyński

14 August 2026

Tooth-bearing structures are commonly involved in the spread of various odontogenic lesions. Radicular and dentigerous cysts are among the most common odontogenic cysts, exhibiting significant variations in size and morphology within the jawbones. On...

(This article belongs to the Special Issue Diagnosis and Management in Otolaryngology, 2nd Edition)
  • Systematic Review
  • Open Access
2 Citations
1,937 Views
20 Pages

Peripheral Odontogenic Keratocyst of the Gingiva: A Systematic Review of the Literature and Case Report

  • Marta Forte,
  • Alfonso Manfuso,
  • Giuseppe D’Albis,
  • Giulia Cianciotta,
  • Eliano Cascardi,
  • Grazia Pinto,
  • Giuseppe Ingravallo,
  • Gianfranco Favia,
  • Antonio d’Amati and
  • Saverio Capodiferro
  • + 1 author

16 October 2025

Background/Objectives: Odontogenic keratocysts are benign cysts originating from remnants of the dental lamina, rarely showing peripheral (gingival) localization. In this study, we compiled data on the peripheral variant by reviewing the literature a...

(This article belongs to the Special Issue Challenges Related to the Oral Cavity, Head and Neck: From Diagnosis to Therapy)
  • Article
  • Open Access
7 Citations
3,922 Views
22 Pages

Deep Learning-Assisted Diagnostic System: Apices and Odontogenic Sinus Floor Level Analysis in Dental Panoramic Radiographs

  • Pei-Yi Wu,
  • Yuan-Jin Lin,
  • Yu-Jen Chang,
  • Sung-Tsun Wei,
  • Chiung-An Chen,
  • Kuo-Chen Li,
  • Wei-Chen Tu and
  • Patricia Angela R. Abu

Odontogenic sinusitis is a type of sinusitis caused by apical lesions of teeth near the maxillary sinus floor. Its clinical symptoms are highly like other types of sinusitis, often leading to misdiagnosis as general sinusitis by dentists in the early...

(This article belongs to the Special Issue Artificial Intelligence Revolution in Biomedical Image and Signal Processing: Innovations and Applications)
  • Case Report
  • Open Access
21 Citations
21,352 Views
14 Pages

Dentigerous cyst is an odontogenic developmental cyst arising from the pericoronal tissue of an impacted tooth, and that may exhibit various radiological aspects. The aim of this article is to present four cases of histologically confirmed mandibular...

(This article belongs to the Topic Diagnostic Imaging in Oral and Maxillofacial Diseases)
  • Case Report
  • Open Access
860 Views
12 Pages

The Diagnostic Challenge of Coexisting Radicular and Nasopalatine Duct Cysts: The Role of CBCT

  • Nermine Joumaa,
  • Liam Rebetez,
  • Tommaso Lombardi and
  • Alexandre Perez

7 July 2026

A 66-year-old female patient was referred to the oral surgery unit for the enucleation of a radicular cyst centered at the apex of the necrotic tooth 12. Initial panoramic and intraoral periapical radiographs suggested a persistent periapical cystic...

  • Review
  • Open Access
2 Citations
3,211 Views
11 Pages

Odontogenic Myxoma Associated to Unerupted Mandibular Molar in a Pediatric Patient: A New Case Description with Comprehensive Literature Analysis

  • Marta Forte,
  • Giuseppe D’Albis,
  • Antonio d’Amati,
  • Giuseppe Ingravallo,
  • Luisa Limongelli,
  • Gianfranco Favia,
  • Adriano Di Grigoli,
  • Anna Montaruli,
  • Daniela Di Venere and
  • Saverio Capodiferro
  • + 1 author

28 January 2025

Background/Objectives: Odontogenic tumors in pediatric patients are uncommon; among all, the intraosseous occurrence of odontogenic myxoma is very rare, accounting for almost 8.5–11.6% of all odontogenic tumors in children. The radiological app...

(This article belongs to the Section Pediatric Dentistry & Oral Medicine)
  • Case Report
  • Open Access
5,587 Views
9 Pages

Odontogenic Keratocyst in an Edentulous Patient: Report of an Unusual Case

  • Alexandre Perez,
  • Valentina Calcoen and
  • Tommaso Lombardi

13 July 2023

The purpose of this study was to report a rare case of an odontogenic keratocyst occurring in the edentulous jaw area. A 64-year-old man presented with a painful swelling of the right posterior mandibular vestibule that prevented him from wearing a c...

  • Article
  • Open Access
1 Citations
416 Views
22 Pages

Perilesional and Contextual Radiomic Features Improve Differentiation of Odontogenic Cysts on Panoramic Radiographs

  • Barbara Obuchowicz,
  • Joanna Zarzecka,
  • Marzena Jakubowska,
  • Rafał Obuchowicz and
  • Julia Lasek

27 July 2026

Background: Radiographic differentiation of odontogenic cysts remains challenging due to overlapping imaging features and limited specificity of conventional assessment. Radiomics offers a quantitative approach to extract imaging biomarkers that may...

(This article belongs to the Topic Machine Learning and Deep Learning in Medical Imaging)
  • Interesting Images
  • Open Access
1 Citations
1,674 Views
7 Pages

A Cystic-like Lesion of Uncertain Origin—A Discussion on Cemento-Osseous Dysplasia and Traumatic Bone Cysts

  • Kamil Nelke,
  • Maciej Karpiński,
  • Michał Scharoch,
  • Maciej Janeczek,
  • Agata Małyszek,
  • Evagelos Kalfarentzos,
  • Efthymios Mavrakos,
  • Piotr Kuropka,
  • Christos Perisanidis and
  • Maciej Dobrzyński

11 September 2025

Mandible cemento-osseous dysplasia (COD) can be found mostly associated with dental roots and tooth-bearing anatomical structures. A variety of odontogenic cysts and tumors might have similar appearances. A lesion in the jaw bone not associated with...

(This article belongs to the Collection Interesting Images)
  • Case Report
  • Open Access
2 Citations
4,695 Views
18 Pages

Odontogenic Sarcomas of the Mandible

  • Jared Akers,
  • Emily Geisler,
  • Suimin Qiu,
  • Petros Konofaos and
  • Hisham Marwan

Odontogenic sarcomas are exceedingly rare and account for less than 5% of all Maxillofacial Sarcomas. It usually affects the younger population. The posterior mandible is the most commonly affected site. Radiographically, it appears as a large destru...

(This article belongs to the Section Cancer Biology and Oncology)
  • Entry
  • Open Access
2 Citations
6,697 Views
16 Pages

Periapical Lesions: Diagnosis, Pathophysiology, and Management

  • Yuval Reiser,
  • Luka Marković,
  • Ivica Pelivan,
  • Ana Ivanišević and
  • Dragana Gabrić

The term “periapical lesion” refers to a pathological change in the tissues surrounding the apex of a tooth root, defined by its anatomical location rather than a distinct disease entity. Periapical lesions may be of endodontic origin, mo...

(This article belongs to the Section Medicine & Pharmacology)
  • Article
  • Open Access
4 Citations
3,369 Views
15 Pages

Human Periapical Odontogenic Granulomas: Aspects of Microvessel Density (MVD), Heterogeneity of Blood Vessels and Mast Cells Density (MCD)

  • Ciprian Roi,
  • Meda Lavinia Negruțiu,
  • Alexandra Roi,
  • Mircea Riviș,
  • Ruxandra Elena Luca,
  • Marius Raica,
  • Raluca Amalia Ceaușu,
  • Alexandru Cătălin Motofelea and
  • Pușa Nela Gaje

Periapical odontogenic granulomas are among the most encountered pathology that involve the alveolar bone, with severe consequences such as bone resorption, the presence of inflammatory infiltrate and the formation of abnormal vascularization. The pr...

(This article belongs to the Special Issue Cell Biology in Dentistry)
  • Article
  • Open Access
1 Citations
4,185 Views
12 Pages

Apical Periodontitis and Maxillary Sinus Alterations: Results of an Exploratory Cross-Sectional Tomographic In Vivo Study

  • Thaïs Coutinho,
  • Lucio Gonçalves,
  • Marilia Fagury Videira Marceliano-Alves,
  • Vivian Ronquete Figueiredo,
  • Josué da Costa Lima Junior,
  • Rafael Vidal Peres and
  • Fábio Vidal

Odontogenic sinusitis is a highly prevalent yet frequently overlooked condition. Since anatomically, the roots of the upper molars and premolars may be in proximity to the maxillary sinus, apical periodontitis affecting these teeth may lead to the de...

  • Article
  • Open Access
174 Citations
20,564 Views
14 Pages

Deep Learning for Automated Detection of Cyst and Tumors of the Jaw in Panoramic Radiographs

  • Hyunwoo Yang,
  • Eun Jo,
  • Hyung Jun Kim,
  • In-ho Cha,
  • Young-Soo Jung,
  • Woong Nam,
  • Jun-Young Kim,
  • Jin-Kyu Kim,
  • Yoon Hyeon Kim and
  • Dongwook Kim
  • + 3 authors

12 June 2020

Patients with odontogenic cysts and tumors may have to undergo serious surgery unless the lesion is properly detected at the early stage. The purpose of this study is to evaluate the diagnostic performance of the real-time object detecting deep convo...

(This article belongs to the Special Issue New Perspectives in Maxillo-Facial Surgery)
  • Case Report
  • Open Access
10 Citations
6,391 Views
8 Pages

Residual Cyst Mimicking an Aggressive Neoplasm—A Life-Threatening Condition

  • Emilia Lis,
  • Michał Gontarz,
  • Tomasz Marecik,
  • Grażyna Wyszyńska-Pawelec and
  • Jakub Bargiel

26 August 2024

Odontogenic cysts are frequently encountered in clinical practice. However, residual cysts, a specific type of inflammatory odontogenic cyst, are relatively rare. These cysts may slowly expand over time, damaging surrounding soft tissues and bone, ty...

  • Case Report
  • Open Access
1 Citations
2,618 Views
15 Pages

Comprehensive Management of Odontogenic Myxofibroma in the Mandible: A Four-Year Follow-Up Case Report with a Review of Differential Diagnosis and Treatment Approaches

  • Joanna Wójcik,
  • Liliia Yefanova,
  • Kacper Nijakowski,
  • Katarzyna Bednarek-Rajewska,
  • Krzysztof Osmola and
  • Maciej Okła

3 June 2025

Odontogenic myxofibroma (OMF) is a rare, benign, and slow-growing tumour arising from odontogenic ectomesenchyme. Despite its low prevalence, accounting for approximately 0.5% to 17.7% of all odontogenic tumours worldwide and 3.1% in specific regiona...

  • Review
  • Open Access
2 Citations
9,060 Views
16 Pages

6 January 2024

Well-defined, faintly radiopaque lesions are occasionally observed in the antrum of the maxillary sinus in asymptomatic patients during maxillary sinus floor elevation. These lesions are treated as antral pseudocysts (AP) based on the clinical diagno...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Case Report
  • Open Access
581 Views
21 Pages

Neuroblastoma Metastasis to the Mandible in Children: A Case Report and Focused Narrative Review of Reported Cases

  • Ronja Marquardt,
  • Simon Hundeshagen,
  • Felix Tilsen,
  • Frank Tavassol and
  • Waldemar Reich

25 July 2026

Background: Neuroblastoma is a common extracranial solid malignant tumor of early childhood; however, mandibular involvement is rare and may mimic odontogenic or inflammatory disease. Case Presentation: We report an 8-month-old girl with left paraman...

(This article belongs to the Section Pediatric Dentistry & Oral Medicine)
  • Interesting Images
  • Open Access
3 Citations
1,786 Views
9 Pages

The Occurrence of Mandible Brown Tumor Mimicking Central Giant Cell Granuloma in a Case Suspicious of Primary Hyperparathyroidism—Troublesome Diagnostic Dilemmas

  • Kamil Nelke,
  • Klaudiusz Łuczak,
  • Maciej Janeczek,
  • Marcelina Plichta,
  • Agata Małyszek,
  • Małgorzata Tarnowska,
  • Piotr Kuropka and
  • Maciej Dobrzyński

14 August 2025

The jaw bones can manifest various cysts and tumors of different origins and etiologies. Any bone lesions lacking any potential odontogenic origin might require more accurate diagnostics, adequate investigation, and careful patient anamnesis. In case...

(This article belongs to the Collection Interesting Images)
  • Interesting Images
  • Open Access
3 Citations
2,617 Views
3 Pages

Pindborg Tumor—An Uncommon Odontogenic Tumor Detected by 68Ga-DOTATOC

  • Anna Herden,
  • Deema Sabtan,
  • Katja Warnecke,
  • Christian Doll and
  • Christian Furth

A 62-year-old-woman with a suspected Tumor-induced-osteomalacia (TIO), a rare neoplastic syndrome that results in renal phosphate wasting with hypophosphatemia, underwent 68Ga-DOTATOC PET/CT on the suspicion of a mesenchymal tumor producing Fibroblas...

(This article belongs to the Special Issue Oral and Maxillofacial Image Diagnosis)

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