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36,192 Results Found

  • Article
  • Open Access
4 Citations
4,165 Views
19 Pages

Four New Species and a New Combination of Boletaceae (Boletales) from Subtropical and Tropical China

  • Rou Xue,
  • Lin-Jie Su,
  • Tai-Jie Yu,
  • Chang Xu,
  • Hong-Yan Huang,
  • Nian-Kai Zeng,
  • Guo-Li Zhang and
  • Li-Ping Tang

13 May 2024

Previous studies have shown that boletes are abundant and diverse in China, especially in tropical and subtropical regions. In the present study, morphological, ecological, host relationship, and a four-locus (28S, tef1, rpb1, and rpb2) molecular phy...

  • Article
  • Open Access
10 Citations
1,560 Views
25 Pages

New Electric Power System Stability Evaluation Based on Game Theory Combination Weighting and Improved Cloud Model

  • Mingrun Tang,
  • Ruoyang Li,
  • Xinyin Dai,
  • Xuefeng Yu,
  • Xiaoyu Cheng and
  • Shuxia Yang

19 July 2024

The development of new electric power system is a requirement for China to realize its “carbon peaking and carbon neutrality goals”, so it is of great importance that we assess the stability of a new electric power system under certain co...

  • Article
  • Open Access
13 Citations
5,721 Views
22 Pages

7 March 2023

GRACE observations and land subsidence data derived from InSAR both assess groundwater storage changes. However, GRACE data at local scales are restricted by the coarser spatial resolution of satellite systems, and inversion of Groundwater Storage An...

  • Review
  • Open Access
75 Citations
8,025 Views
57 Pages

Salvianolic Acid B: A Review of Pharmacological Effects, Safety, Combination Therapy, New Dosage Forms, and Novel Drug Delivery Routes

  • Guannan He,
  • Guangfeng Chen,
  • Weidong Liu,
  • Dongxue Ye,
  • Xuehuan Liu,
  • Xiaodong Liang and
  • Jing Song

Salvianolic acid B is extracted from the roots and rhizomes of Danshen (Salvia miltiorrhiza Bge., family Labiatae). It is a water-soluble, weakly acidic drug that has demonstrated antitumor and anti-inflammatory effects on various organs and tissues...

  • Article
  • Open Access
40 Citations
4,760 Views
22 Pages

One New Species and Two New Host Records of Apiospora from Bamboo and Maize in Northern Thailand with Thirteen New Combinations

  • Xingguo Tian,
  • Samantha C. Karunarathna,
  • Ausana Mapook,
  • Itthayakorn Promputtha,
  • Jianchu Xu,
  • Danfeng Bao and
  • Saowaluck Tibpromma

11 October 2021

The genus Apiospora is known as a cosmopolitan genus, found across various substrates. In this study, four Apiospora taxa were obtained from the decaying stems of bamboo and maize in northern Thailand. Apiospora collections were compared with known s...

  • Article
  • Open Access
10 Citations
7,427 Views
22 Pages

30 April 2023

Species of Cystolepiota are known as diminutive lepiotaceous fungi with a worldwide distribution. Previous studies revealed that Cystolepiota is not monophyletic and preliminary DNA sequence data from recent collections suggested that several new spe...

  • Article
  • Open Access
6 Citations
1,905 Views
19 Pages

26 October 2023

With the rapid increase in new energy penetration, the uncertainty of the power system increases sharply. We can smooth out fluctuations and promote the more grid-friendly integration of new energy by combining it with energy storage. This paper prop...

  • Review
  • Open Access
1 Citations
3,046 Views
18 Pages

Perovskite Topological Lasers: A Brand New Combination

  • Liangshen Wang,
  • Lijie Wu and
  • Yong Pan

21 December 2023

Nanolasers are the essential components of modern photonic chips due to their low power consumption, high energy efficiency and fast modulation. As nanotechnology has advanced, researchers have proposed a number of nanolasers operating at both wavele...

  • Article
  • Open Access
3 Citations
2,450 Views
19 Pages

Surfacing Positioning Point Prediction of Underwater Glider with a New Combination Model

  • Runfeng Zhang,
  • Wendong Niu,
  • Xu Wan,
  • Yining Wu,
  • Dongyang Xue and
  • Shaoqiong Yang

Combination prediction models have gained great development in the area of information science, and are widely applied in engineering fields. The underwater glider (UG) is a new type of unmanned vehicle used in ocean observation for the advantages of...

  • Review
  • Open Access
32 Citations
6,732 Views
27 Pages

Overview of New Treatments with Immunotherapy for Breast Cancer and a Proposal of a Combination Therapy

  • Miguel Angel Galván Morales,
  • Raúl Barrera Rodríguez,
  • Julio Raúl Santiago Cruz and
  • Luis M. Teran

2 December 2020

According to data from the U.S. National Cancer Institute, cancer is one of the leading causes of death worldwide with approximately 14 million new cases and 8.2 million cancer-related deaths in 2018. More than 60% of the new annual cases in the worl...

  • Article
  • Open Access
1 Citations
1,045 Views
17 Pages

A new predefined time sliding mode control theme is proposed and applies to the multi-switch combination–combination synchronization (MSCCS) of fractional-order (FO) hyperchaotic systems. Firstly, based on the Lyapunov stability theory, we demo...

  • Review
  • Open Access
16 Citations
4,840 Views
15 Pages

18 December 2021

Background: The objective of the present study was to review the essential knowledge about the combinations of the most commonly used or under development targeted treatments and radiation therapy (RT). Methods: Preclinical and clinical studies inves...

  • Feature Paper
  • Article
  • Open Access
28 Citations
4,040 Views
14 Pages

Graphene Oxide-Linezolid Combination as Potential New Anti-Tuberculosis Treatment

  • Flavio De Maio,
  • Valentina Palmieri,
  • Giulia Santarelli,
  • Giordano Perini,
  • Alessandro Salustri,
  • Ivana Palucci,
  • Michela Sali,
  • Jacopo Gervasoni,
  • Aniello Primiano and
  • Massimiliano Papi
  • + 3 authors

22 July 2020

Global pandemic management represents a serious issue for health systems. In some cases, repurposing of existing medications might help find compounds that have the unexpected potential to combat microorganisms. In the same way, changing cell–d...

  • Review
  • Open Access
68 Citations
16,451 Views
25 Pages

New Drugs for the Treatment of Pseudomonas aeruginosa Infections with Limited Treatment Options: A Narrative Review

  • Angela Raffaella Losito,
  • Francesca Raffaelli,
  • Paola Del Giacomo and
  • Mario Tumbarello

P. aeruginosa is still one of the most threatening pathogens responsible for serious hospital-acquired infections. It is intrinsically resistant to many antimicrobial agents and additional acquired resistance further complicates the management of suc...

  • Article
  • Open Access
1,304 Views
19 Pages

The art of food–drink pairing has always fascinated gourmets and cooking enthusiasts. While wine has long held pride of place on the table, natural mineral water plays a central role in this new concept. Through the Pyramid of Natural Mineral W...

  • Review
  • Open Access
13 Citations
8,592 Views
13 Pages

New β-Lactam/β-Lactamase Inhibitor Combination Antibiotics

  • Maria Sargianou,
  • Panagiotis Stathopoulos,
  • Christos Vrysis,
  • Iva D. Tzvetanova and
  • Matthew E. Falagas

The growing problem of infections due to pathogens with antimicrobial resistance, especially Gram-negative bacteria, has led to the development of new β-lactam/β-lactamase inhibitor combination antibiotics. During the last 2 years from the...

  • Article
  • Open Access
243 Citations
73,267 Views
24 Pages

How to Respond to the Fourth Industrial Revolution, or the Second Information Technology Revolution? Dynamic New Combinations between Technology, Market, and Society through Open Innovation

  • MinHwa Lee,
  • JinHyo Joseph Yun,
  • Andreas Pyka,
  • DongKyu Won,
  • Fumio Kodama,
  • Giovanni Schiuma,
  • HangSik Park,
  • Jeonghwan Jeon,
  • KyungBae Park and
  • Xiaofei Zhao
  • + 2 authors

Since Klaus Schwab and the World Economic Forum declared the arrival of the Fourth Industrial Revolution, there has been much discussion about it. However, there is no commonly agreed-upon definition of the Fourth Industrial Revolution. Therefore, we...

  • Article
  • Open Access
1 Citations
2,355 Views
17 Pages

Onvansertib and Navitoclax Combination as a New Therapeutic Option for Mucinous Ovarian Carcinoma

  • Serena Petrella,
  • Marika Colombo,
  • Mirko Marabese,
  • Chiara Grasselli,
  • Andrea Panfili,
  • Michela Chiappa,
  • Valentina Sancisi,
  • Ilaria Craparotta,
  • Maria C. Barbera and
  • Giovanna Damia
  • + 1 author

Mucinous epithelial ovarian cancer (mEOC) is a rare subtype of epithelial ovarian cancer, characterized by poor responses to standard platinum-based chemotherapy. Polo-like kinase 1 (PLK1) is a key regulator of mitosis and cell cycle progression and...

  • Article
  • Open Access
3 Citations
3,635 Views
24 Pages

19 March 2024

Two new species of Boletaceae (Hortiboletus rubroreticulatus and Tylopilus aurantiovulpinus) discovered during an investigation of the mycobiota of Central Vietnam (Kon Chu Rang Nature Reserve; Ta Dung National Park; Bidoup—Nui Ba National Park...

  • Article
  • Open Access
7 Citations
5,631 Views
50 Pages

1 March 2019

A necro-coprophagous new genus tha is widespread in the whole Sub-Saharan Africa was identified within the tribe Onthophagini and named Tiaronthophagus n.gen. The new genus, which is well characterized by an exclusive set of characters, comprises, at...

  • Article
  • Open Access
21 Citations
3,092 Views
22 Pages

Cyclin-Dependent Kinases (CDKs) and the Human Cytomegalovirus-Encoded CDK Ortholog pUL97 Represent Highly Attractive Targets for Synergistic Drug Combinations

  • Markus Wild,
  • Friedrich Hahn,
  • Nadine Brückner,
  • Martin Schütz,
  • Christina Wangen,
  • Sabrina Wagner,
  • Mona Sommerer,
  • Stefan Strobl and
  • Manfred Marschall

24 February 2022

Human cytomegalovirus (HCMV) is a pathogenic human herpesvirus associated with serious, potentially life-threatening symptoms in the immunocompromised or immunonaïve host. The limitations encountered by antiviral therapy options currently availa...

  • Article
  • Open Access
5 Citations
9,072 Views
22 Pages

16 October 2020

We reviewed the species-level classification of Metriorrhynchina net-winged beetles to make the group accessible for further studies. Altogether, 876 valid species are listed in a checklist along with known synonyms, combinations, and distribution da...

  • Article
  • Open Access
3 Citations
3,748 Views
26 Pages

31 July 2023

The assassin bug genus Argolis Stål, 1861 (Hemiptera: Reduviidae: Stenopodainae) has a disjunct distribution in Sub-Saharan Africa and Asia. In the present study, the Asian species of Argolis are revised. Two species are recognized, redescribed...

  • Article
  • Open Access
2,679 Views
44 Pages

12 January 2025

The nomenclatural and taxonomic issues regarding the thread-legged bug genera Pleias Kirkaldy, 1901 and Bagauda Bergroth, 1903 are reviewed, and Pleias is concluded to be the valid name of the genus. A comprehensive review of Pleias is conducted, res...

  • Article
  • Open Access
5 Citations
1,767 Views
19 Pages

7 December 2022

This paper discusses the power generation characteristics between new energy and traditional energy. This paper uses different energy alliance operation modes for a power system led by new energy power generation. The peak-valley power imbalance issu...

  • Review
  • Open Access
16 Citations
11,259 Views
20 Pages

7 July 2022

Triple-negative breast cancer (TNBC) has a worse prognosis and remains the most challenging breast cancer subtype to treat. This is largely related to the heterogeneity of this disease and the lack of reliable oncological targets. In this review, we...

  • Article
  • Open Access
615 Views
27 Pages

11 December 2025

Iris speculatrix was described from plants collected in Hong Kong and is accepted to extend through southeastern China. The species is scheduled under the Forestry Regulations and is regarded as endangered (EN) according to the IUCN categories. This...

  • Review
  • Open Access
36 Citations
7,530 Views
26 Pages

22 April 2019

During recent years, synthetic methods combining microwaves and ionic liquids became accepted as a promising methodology for various materials preparations because of their high efficiency and low energy consumption. Ionic liquids with high polarity...

  • Review
  • Open Access
36 Citations
6,819 Views
18 Pages

16 March 2021

The approval of Bruton’s tyrosine kinase (BTK) inhibitors such as ibrutinib and acalabrutinib and the Bcl-2 inhibitor venetoclax have revolutionized the treatment of chronic lymphocytic leukemia (CLL). While these novel agents alone or in combination...

  • Article
  • Open Access
6 Citations
3,350 Views
14 Pages

8 January 2023

A single sensor is prone to decline recognition accuracy in the face of a complex environment, while the existing multi-sensor evidence theory fusion methods do not comprehensively consider the impact of evidence conflict and fuzziness. In this paper...

  • Article
  • Open Access
4 Citations
1,673 Views
24 Pages

6 October 2024

This paper presents a new slant insertion-opening combination sand fence designed to reduce the hazards of traditional railway sand damage along the line. This new fence aims to decrease the disturbance caused by lateral wind on the high-speed railwa...

  • Article
  • Open Access
7 Citations
3,363 Views
23 Pages

Effects of a New Combination of Natural Extracts on Glaucoma-Related Retinal Degeneration

  • Claudio Molinari,
  • Sara Ruga,
  • Mahitab Farghali,
  • Rebecca Galla,
  • Rosario Fernandez-Godino,
  • Nausicaa Clemente and
  • Francesca Uberti

15 August 2021

Background: Glaucoma is currently the leading cause of irreversible blindness; it is a neuropathy characterized by structural alterations of the optic nerve, leading to visual impairments. The aim of this work is to develop a new oral formulation abl...

  • Article
  • Open Access
29 Citations
8,736 Views
22 Pages

10 April 2015

The emergence of multi-drug-resistant bacteria, coupled with the lack of new antibiotics in development, is fast evolving into a global crisis. New strategies utilizing existing antibacterial agents are urgently needed. We propose one such strategy i...

  • Article
  • Open Access
5 Citations
2,477 Views
18 Pages

New Formulation–Microporation Combination Approaches to Delivering Ciclopirox across Human Nails

  • Juliana Kishishita,
  • Camila de Almeida Perez Pimenta,
  • Danielle Patricia Cerqueira Macedo,
  • M. Begoña Delgado-Charro and
  • Leila Bastos Leal

Topical treatments for onychomycosis are of interest to those seeking to avoid systemic drug interactions and to improve systemic safety. This work aimed to develop aqueous-based, simple, and cost-effective vehicles that provide high solubility for c...

  • Article
  • Open Access
14 Citations
2,288 Views
25 Pages

A New Power System Source-End Low Carbonization Evaluation System Considering Carbon Control Model

  • Gangjun Gong,
  • Ren Qiang,
  • Jiaxuan Yang,
  • Rui Hou,
  • Zeming Lv,
  • Mingfeng Xu,
  • Xuesong Liu and
  • Haixia Yang

1 January 2023

Under the global goal of “carbon peaking and carbon neutrality”, new power system is facing a new energy development trend of increasing the capacity of new energy and reducing the capacity and quantity of coal power. Furthermore, new pow...

  • Article
  • Open Access
29 Citations
6,053 Views
18 Pages

Exploitation of Potentially New Antibiotics from Mangrove Actinobacteria in Maowei Sea by Combination of Multiple Discovery Strategies

  • Qin-Pei Lu,
  • Jing-Jing Ye,
  • Yong-Mei Huang,
  • Di Liu,
  • Li-Fang Liu,
  • Kun Dong,
  • Elizaveta A. Razumova,
  • Ilya A. Osterman,
  • Petr V. Sergiev and
  • Cheng-Hang Sun
  • + 2 authors

Rediscovery of known antibiotics from actinobacteria, especially Streptomyces, has become a bottleneck issue. Nowadays, more specific identification and dereplication could be acquired by a combination of modern analytic techniques with various datab...

  • Article
  • Open Access
7 Citations
3,441 Views
13 Pages

11 August 2018

Research on cytokine recognition is of great significance in the medical field due to the fact cytokines benefit the diagnosis and treatment of diseases, but the current methods for cytokine recognition have many shortcomings, such as low sensitivity...

  • Review
  • Open Access
30 Citations
5,966 Views
16 Pages

The Interplay between PARP Inhibitors and Immunotherapy in Ovarian Cancer: The Rationale behind a New Combination Therapy

  • Brigida Anna Maiorano,
  • Domenica Lorusso,
  • Mauro Francesco Pio Maiorano,
  • Davide Ciardiello,
  • Paola Parrella,
  • Antonio Petracca,
  • Gennaro Cormio and
  • Evaristo Maiello

Ovarian cancer (OC) has a high impact on morbidity and mortality in the female population. Survival is modest after platinum progression. Therefore, the search for new therapeutic strategies is of utmost importance. BRCA mutations and HR-deficiency o...

  • Article
  • Open Access
31 Citations
4,347 Views
23 Pages

Forecasting Day-Ahead Electricity Prices for the Italian Electricity Market Using a New Decomposition—Combination Technique

  • Hasnain Iftikhar,
  • Josue E. Turpo-Chaparro,
  • Paulo Canas Rodrigues and
  • Javier Linkolk López-Gonzales

18 September 2023

Over the last 30 years, day-ahead electricity price forecasts have been critical to public and private decision-making. This importance has increased since the global wave of deregulation and liberalization in the energy sector at the end of the 1990...

  • Article
  • Open Access
16 Citations
3,228 Views
19 Pages

Ethics and Meditation: A New Educational Combination to Boost Verbal Creativity and Sense of Responsibility

  • Hélène Hagège,
  • Mohammed El Ourmi,
  • Rebecca Shankland,
  • France Arboix-Calas,
  • Christophe Leys and
  • Todd Lubart

Both creativity and responsibility are important higher-order skills to develop to meet the challenges of the Anthropocene, and both are related to attentional states of consciousness and to ethics. Meditation is a set of practices that trains attent...

  • Article
  • Open Access
327 Views
35 Pages

This study explores a learning knowledge representation, using an iteratively reevaluated lattice of equivalence-classified properties. The proposed methodology is based on the evaluation feedback between the maximal and minimal elements of the compa...

  • Review
  • Open Access
220 Citations
22,174 Views
21 Pages

Irinotecan has been used in the treatment of various malignancies for many years. Still, the knowledge regarding this drug is expanding. The pharmacogenetics of the drug is the crucial component of response to irinotecan. Furthermore, new formulation...

  • Article
  • Open Access
1 Citations
1,286 Views
13 Pages

28 February 2025

Based on several sources of evidence from morphology, the micromorphology of the abaxial leaf epidermis, and a phylogenetic analysis using complete chloroplast genome data, a new combination and two new synonyms are reported in the genus Indocalamus...

  • Article
  • Open Access
18 Citations
5,754 Views
10 Pages

A New Twist: The Combination of Sulbactam/Avibactam Enhances Sulbactam Activity against Carbapenem-Resistant Acinetobacter baumannii (CRAB) Isolates

  • Fernando Pasteran,
  • Jose Cedano,
  • Michelle Baez,
  • Ezequiel Albornoz,
  • Melina Rapoport,
  • Jose Osteria,
  • Sabrina Montaña,
  • Casin Le,
  • Grace Ra and
  • Maria Soledad Ramirez
  • + 3 authors

An increasing number of untreatable infections are recorded every year. Many studies have focused their efforts on developing new β-lactamase inhibitors to treat multi-drug resistant (MDR) isolates. In the present study, sulbactam/avibactam and sulba...

  • Article
  • Open Access
16 Citations
4,861 Views
28 Pages

Combination of Solid State and Submerged Fermentation Strategies to Produce a New Jellyfish-Based Food

  • Francesca Anna Ramires,
  • Gianluca Bleve,
  • Stefania De Domenico and
  • Antonella Leone

8 December 2022

This study describes the set-up and optimization of a fermentation strategy applied to a composite raw material containing jellyfish biomass as the principal ingredient. New fermented food was developed by combining fresh jellyfish Rhizostoma pulmo a...

  • Article
  • Open Access
8 Citations
3,021 Views
16 Pages

9 December 2021

Clavicle injuries are common, but only few case reports describe combined clavicular injuries (CCI). CCI include combinations between clavicular fractures and acromioclavicular/sternoclavicular joint dislocations (SCJD). We present the first general...

  • Article
  • Open Access
9 Citations
3,967 Views
12 Pages

21 May 2020

Herein, a novel process of diesel exhaust purification by non-thermal plasma combined with wood fiber has been investigated to understand the effect of purification efficiency on the emission. The dielectric barrier discharge (DBD) and wood fiber (WF...

  • Review
  • Open Access
5 Citations
3,518 Views
20 Pages

23 August 2023

Background: Numerous studies have been developed in an attempt to understand which factors best predict improvements in cognitive function in the elderly such as exergaming. The aim of this study was to investigate and systematize literature on inter...

  • Systematic Review
  • Open Access
10 Citations
6,639 Views
17 Pages

Although the dopamine hypothesis of schizophrenia explains the effects of all the available antipsychotics in clinical use, there is an increasing need for developing new drugs for the treatment of the positive, negative, and cognitive symptoms of ch...

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