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35 pages, 3601 KiB  
Article
Carbon Emissions and Influencing Factors in the Areas Along the Belt and Road Initiative in Africa: A Spatial Spillover Perspective
by Suxin Yang and Miguel Ángel Benedicto Solsona
Sustainability 2025, 17(15), 7098; https://doi.org/10.3390/su17157098 (registering DOI) - 5 Aug 2025
Abstract
The carbon dioxide spillover effects and influencing factors of the “Belt and Road Initiative” (BRI) in African countries must be assessed to evaluate the effectiveness, promote low-carbon transmissions in African countries, and provide recommendations for achieving the 2030 Sustainable Development Goals. This novel [...] Read more.
The carbon dioxide spillover effects and influencing factors of the “Belt and Road Initiative” (BRI) in African countries must be assessed to evaluate the effectiveness, promote low-carbon transmissions in African countries, and provide recommendations for achieving the 2030 Sustainable Development Goals. This novel study employs carbon dioxide emission intensity (CEI) and per capita carbon dioxide emissions (PCE) as dual indicators to evaluate the spatial spillover effects of 54 BRI African countries on their neighboring countries’ carbon emissions from 2007 to 2023. It identifies the key factors and mechanisms affecting these spillover effects using the spatial differences-in-differences (SDID) model. Results indicate that since the launch of the BRI, the CEI and PCE of BRI African countries have significantly increased, largely due to trade patterns and industrialization structures. Greater trade openness has further boosted local economic development, thereby increasing carbon dioxide’s spatial spillover. Government management and corruption control levels show some heterogeneity in the spillover effects, which may be attributed to long-standing issues of weak institutional enforcement in Africa. Overall, this study reveals the complex relationship between BRI African economic development and environmental outcomes, highlighting the importance of developing sustainable development strategies and establishing strong differentiated regulatory regimes to effectively address environmental challenges. Full article
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23 pages, 3087 KiB  
Article
MCMBAN: A Masked and Cascaded Multi-Branch Attention Network for Bearing Fault Diagnosis
by Peng Chen, Haopeng Liang and Alaeldden Abduelhadi
Machines 2025, 13(8), 685; https://doi.org/10.3390/machines13080685 - 4 Aug 2025
Abstract
In recent years, deep learning methods have made breakthroughs in the field of rotating equipment fault diagnosis, thanks to their powerful data analysis capabilities. However, the vibration signals usually incorporate fault features and background noise, and these features may be scattered over multiple [...] Read more.
In recent years, deep learning methods have made breakthroughs in the field of rotating equipment fault diagnosis, thanks to their powerful data analysis capabilities. However, the vibration signals usually incorporate fault features and background noise, and these features may be scattered over multiple frequency levels, which increases the complexity of extracting important information from them. To address this problem, this paper proposes a Masked and Cascaded Multi-Branch Attention Network (MCMBAN), which combines the Noise Mask Filter Block (NMFB) with the Multi-Branch Cascade Attention Block (MBCAB), and significantly improves the noise immunity of the fault diagnostic model and the efficiency of fault feature extraction. NMFB novelly combines a wide convolutional layer and a top k neighbor self-attention masking mechanism, so as to efficiently filter unnecessary high-frequency noise in the vibration signal. On the other hand, MBCAB strengthens the interaction between different layers by cascading the convolutional layers of different scales, thus improving the recognition of periodic fault signals and greatly enhancing the diagnosis accuracy of the model when processing complex signals. Finally, the time–frequency analysis technique is employed to explore the internal mechanisms of the model in depth, aiming to validate the effectiveness of NMFB and MBCAB in fault feature recognition and to improve the feature interpretability of the proposed modes in fault diagnosis applications. We validate the superior performance of the network model in dealing with high-noise backgrounds by testing it on a standard bearing dataset from Case Western Reserve University and a self-constructed composite bearing fault dataset, and the experimental results show that its performance exceeded six of the top current fault diagnosis techniques. Full article
(This article belongs to the Special Issue Fault Diagnosis and Fault Tolerant Control in Mechanical System)
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19 pages, 1997 KiB  
Article
Mapping Bicycle Crash-Prone Areas in Ohio Using Exploratory Spatial Data Analysis Techniques: An Investigation into Ohio DOT’s GIS Crash Analysis Tool Data
by Modabbir Rizwan, Bhuiyan Monwar Alam and Yaw Kwarteng
Future Transp. 2025, 5(3), 103; https://doi.org/10.3390/futuretransp5030103 - 4 Aug 2025
Abstract
While there are studies on bicycle crashes, no study has investigated the spatial analysis of fatal and injury bicycle crashes in the state of Ohio. This study fills this gap in the literature by mapping and investigating the bicycle crash-prone areas in the [...] Read more.
While there are studies on bicycle crashes, no study has investigated the spatial analysis of fatal and injury bicycle crashes in the state of Ohio. This study fills this gap in the literature by mapping and investigating the bicycle crash-prone areas in the state. It analyzes fatal and injury bicycle crashes from 2014 to 2023 by utilizing four exploratory spatial data analysis techniques: nearest neighbor index, global Moran’s I index, hotspot and cold spot analysis, and local Moran’s I index at the state, county, census tract, and block group levels. Results vary slightly across techniques and spatial scales but consistently show that bicycle crash locations are clustered statewide, particularly in the state’s major metropolitan areas such as Columbus, Cincinnati, Toledo, Cleveland, and Akron. These urban centers have emerged as hotspots, indicating a higher vulnerability to bicycle crashes. While global Moran’s I analysis at the county level does not reveal significant spatial autocorrelation, a strong positive autocorrelation is observed at both the census tract (p = 0.01) and block group (p = 0.00) levels, indicating significant high clustering, signifying that finer geographical units yield more robust results. Identifying specific hotspots and vulnerable areas provides valuable insights for policymakers and urban planners to implement effective safety measures and improve conditions for non-motorized road users in Ohio. The study highlights the need for targeted mitigation strategies in high-risk areas, including comprehensive safety measures, infrastructure improvements, policy changes, and community-focused initiatives to reduce crash risk and create safer environments for cyclists throughout Ohio’s urban fabric. Full article
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28 pages, 41726 KiB  
Article
Robust Unsupervised Feature Selection Algorithm Based on Fuzzy Anchor Graph
by Zhouqing Yan, Ziping Ma, Jinlin Ma and Huirong Li
Entropy 2025, 27(8), 827; https://doi.org/10.3390/e27080827 (registering DOI) - 4 Aug 2025
Abstract
Unsupervised feature selection aims to characterize the cluster structure of original features and select the optimal subset without label guidance. However, existing methods overlook fuzzy information in the data, failing to model cluster structures between data effectively, and rely on squared error for [...] Read more.
Unsupervised feature selection aims to characterize the cluster structure of original features and select the optimal subset without label guidance. However, existing methods overlook fuzzy information in the data, failing to model cluster structures between data effectively, and rely on squared error for data reconstruction, exacerbating noise impact. Therefore, a robust unsupervised feature selection algorithm based on fuzzy anchor graphs (FWFGFS) is proposed. To address the inaccuracies in neighbor assignments, a fuzzy anchor graph learning mechanism is designed. This mechanism models the association between nodes and clusters using fuzzy membership distributions, effectively capturing potential fuzzy neighborhood relationships between nodes and avoiding rigid assignments to specific clusters. This soft cluster assignment mechanism improves clustering accuracy and the robustness of the graph structure while maintaining low computational costs. Additionally, to mitigate the interference of noise in the feature selection process, an adaptive fuzzy weighting mechanism is presented. This mechanism assigns different weights to features based on their contribution to the error, thereby reducing errors caused by redundant features and noise. Orthogonal tri-factorization is applied to the low-dimensional representation matrix. This guarantees that each center represents only one class of features, resulting in more independent cluster centers. Experimental results on 12 public datasets show that FWFGFS improves the average clustering accuracy by 5.68% to 13.79% compared with the state-of-the-art methods. Full article
(This article belongs to the Section Information Theory, Probability and Statistics)
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25 pages, 3258 KiB  
Article
MTRSRP: Joint Design of Multi-Triangular Ring and Self-Routing Protocol for BLE Networks
by Tzuen-Wuu Hsieh, Jian-Ping Lin, Chih-Min Yu, Meng-Lin Ku and Li-Chun Wang
Sensors 2025, 25(15), 4773; https://doi.org/10.3390/s25154773 - 3 Aug 2025
Viewed by 63
Abstract
This paper presents the multi-triangular ring and self-routing protocol (MTRSRP), which is a new decentralized strategy designed to boost throughput and network efficiency in multiring scatternets. MTRSRP comprises two primary phases: leader election and scatternet formation, which collaborate to establish an effective multi-triangular [...] Read more.
This paper presents the multi-triangular ring and self-routing protocol (MTRSRP), which is a new decentralized strategy designed to boost throughput and network efficiency in multiring scatternets. MTRSRP comprises two primary phases: leader election and scatternet formation, which collaborate to establish an effective multi-triangular ring topology. In the leader election phase, nodes exchange broadcast messages to gather neighbor information and elect coordinators through a competitive process. The scatternet formation phase determines the optimal number of rings based on the coordinator’s collected node information and predefined rules. The master nodes then send unicast connection requests to establish piconets within the scatternet, following a predefined role table. Intra- and inter-bridge nodes were activated to interconnect the piconets, creating a cohesive multi-triangular ring scatternet. Additionally, MTRSRP incorporates a self-routing addressing scheme within the triangular ring architecture, optimizing packet transmission paths and reducing overhead by utilizing master/slave relationships established during scatternet formation. Simulation results indicate that MTRSRP with dual-bridge connectivity outperforms the cluster-based on-demand routing protocol and Bluetooth low-energy mesh schemes in key network transmission performance metrics such as the transmission rate, packet delay, and delivery ratio. In summary, MTRSRP significantly enhances throughput, optimizes routing paths, and improves network efficiency in multi-ring scatternets through its multi-triangular ring topology and self-routing capabilities. Full article
(This article belongs to the Special Issue Advances in Wireless Sensor and Mobile Networks)
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17 pages, 3038 KiB  
Article
Neighbor Relatedness Contributes to Improvement in Grain Yields in Rice Cultivar Mixtures
by You Xu, Qin-Hang Han, Shuai-Shuai Xie and Chui-Hua Kong
Plants 2025, 14(15), 2385; https://doi.org/10.3390/plants14152385 - 2 Aug 2025
Viewed by 222
Abstract
The improvement in yield in cultivar mixtures has been well established. Despite increasing knowledge of the improvement involving within-species diversification and resource use efficiency, little is known about the benefits arising from relatedness-mediated intraspecific interactions in cultivar mixtures. This study used a relatedness [...] Read more.
The improvement in yield in cultivar mixtures has been well established. Despite increasing knowledge of the improvement involving within-species diversification and resource use efficiency, little is known about the benefits arising from relatedness-mediated intraspecific interactions in cultivar mixtures. This study used a relatedness gradient of rice cultivars to test whether neighbor relatedness contributes to improvements in grain yields in cultivar mixtures. We experimentally demonstrated the grain yield of rice cultivar mixtures with varying genetic relatedness under both field and controlled conditions. As a result, a closely related cultivar mixture had increased grain yield compared to monoculture and distantly related mixtures by optimizing the root-to-shoot ratio and accelerating flowering. The benefits over monoculture were most pronounced when compared to the significant yield reductions observed in distantly related mixtures. The relatedness-mediated improvement in yields depended on soil volume and nitrogen use level, with effects attenuating under larger soil volumes or nitrogen deficiency. Furthermore, neighbor relatedness enhanced the richness and diversity of both bacterial and fungal communities in the rhizosphere soil, leading to a significant restructuring of the microbial community composition. These findings suggest that neighbor relatedness may improve the grain yield of rice cultivar mixtures. Beneficial plant–plant interactions may be generated by manipulating cultivar kinship within a crop species. A thorough understanding of kinship strategies in cultivar mixtures offers promising prospects for increasing crop production. Full article
(This article belongs to the Special Issue Plant Chemical Ecology—2nd Edition)
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21 pages, 1646 KiB  
Article
How Does New Quality Productive Forces Affect Green Total Factor Energy Efficiency in China? Consider the Threshold Effect of Artificial Intelligence
by Boyu Yuan, Runde Gu, Peng Wang and Yuwei Hu
Sustainability 2025, 17(15), 7012; https://doi.org/10.3390/su17157012 - 1 Aug 2025
Viewed by 201
Abstract
China’s economy is shifting from an era of rapid expansion to one focused on high-quality development, making it imperative to tackle environmental degradation linked to energy use. Understanding how New Quality Productive Forces (NQPF) interact with energy efficiency, along with the mechanisms driving [...] Read more.
China’s economy is shifting from an era of rapid expansion to one focused on high-quality development, making it imperative to tackle environmental degradation linked to energy use. Understanding how New Quality Productive Forces (NQPF) interact with energy efficiency, along with the mechanisms driving this relationship, is essential for economic transformation and long-term sustainability. This study establishes an evaluation framework for NQPF, integrating technological, green, and digital dimensions. We apply fixed-effects models, the spatial Durbin model (SDM), a moderation model, and a threshold model to analyze the influence of NQPF on Green Total Factor Energy Efficiency (GTFEE) and its spatial implications. This underscores the necessity of distinguishing it from traditional productivity frameworks and adopting a new analytical perspective. Furthermore, by considering dimensions such as input, application, innovation capability, and market efficiency, we reveal the moderating role and heterogeneous effects of artificial intelligence (AI). The findings are as follows: The development of NQPF significantly enhances GTFEE, and the conclusion remains robust after tail reduction and endogeneity tests. NQPF has a positive spatial spillover effect on GTFEE; that is, while improving the local GTFEE, it also improves neighboring regions GTFEE. The advancement of AI significantly strengthens the positive impact of NQPF on GTFEE. AI exhibits a significant U-shaped threshold effect: as AI levels increase, its moderating effect transitions from suppression to facilitation, with marginal benefits gradually increasing over time. Full article
(This article belongs to the Section Energy Sustainability)
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22 pages, 2120 KiB  
Article
Machine Learning Algorithms and Explainable Artificial Intelligence for Property Valuation
by Gabriella Maselli and Antonio Nesticò
Real Estate 2025, 2(3), 12; https://doi.org/10.3390/realestate2030012 - 1 Aug 2025
Viewed by 146
Abstract
The accurate estimation of urban property values is a key challenge for appraisers, market participants, financial institutions, and urban planners. In recent years, machine learning (ML) techniques have emerged as promising tools for price forecasting due to their ability to model complex relationships [...] Read more.
The accurate estimation of urban property values is a key challenge for appraisers, market participants, financial institutions, and urban planners. In recent years, machine learning (ML) techniques have emerged as promising tools for price forecasting due to their ability to model complex relationships among variables. However, their application raises two main critical issues: (i) the risk of overfitting, especially with small datasets or with noisy data; (ii) the interpretive issues associated with the “black box” nature of many models. Within this framework, this paper proposes a methodological approach that addresses both these issues, comparing the predictive performance of three ML algorithms—k-Nearest Neighbors (kNN), Random Forest (RF), and the Artificial Neural Network (ANN)—applied to the housing market in the city of Salerno, Italy. For each model, overfitting is preliminarily assessed to ensure predictive robustness. Subsequently, the results are interpreted using explainability techniques, such as SHapley Additive exPlanations (SHAPs) and Permutation Feature Importance (PFI). This analysis reveals that the Random Forest offers the best balance between predictive accuracy and transparency, with features such as area and proximity to the train station identified as the main drivers of property prices. kNN and the ANN are viable alternatives that are particularly robust in terms of generalization. The results demonstrate how the defined methodological framework successfully balances predictive effectiveness and interpretability, supporting the informed and transparent use of ML in real estate valuation. Full article
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28 pages, 10147 KiB  
Article
Construction of Analogy Indicator System and Machine-Learning-Based Optimization of Analogy Methods for Oilfield Development Projects
by Muzhen Zhang, Zhanxiang Lei, Chengyun Yan, Baoquan Zeng, Fei Huang, Tailai Qu, Bin Wang and Li Fu
Energies 2025, 18(15), 4076; https://doi.org/10.3390/en18154076 - 1 Aug 2025
Viewed by 231
Abstract
Oil and gas development is characterized by high technical complexity, strong interdisciplinarity, long investment cycles, and significant uncertainty. To meet the need for quick evaluation of overseas oilfield projects with limited data and experience, this study develops an analogy indicator system and tests [...] Read more.
Oil and gas development is characterized by high technical complexity, strong interdisciplinarity, long investment cycles, and significant uncertainty. To meet the need for quick evaluation of overseas oilfield projects with limited data and experience, this study develops an analogy indicator system and tests multiple machine-learning algorithms on two analogy tasks to identify the optimal method. Using an initial set of basic indicators and a database of 1436 oilfield samples, a combined subjective–objective weighting strategy that integrates statistical methods with expert judgment is used to select, classify, and assign weights to the indicators. This process results in 26 key indicators for practical analogy analysis. Single-indicator and whole-asset analogy experiments are then performed with five standard machine-learning algorithms—support vector machine (SVM), random forest (RF), backpropagation neural network (BP), k-nearest neighbor (KNN), and decision tree (DT). Results show that SVM achieves classification accuracies of 86% and 95% in medium-high permeability sandstone oilfields, respectively, greatly surpassing other methods. These results demonstrate the effectiveness of the proposed indicator system and methodology, providing efficient and objective technical support for evaluating and making decisions on overseas oilfield development projects. Full article
(This article belongs to the Section H1: Petroleum Engineering)
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25 pages, 17227 KiB  
Article
Distributed Online Voltage Control with Feedback Delays Under Coupled Constraints for Distribution Networks
by Jinxuan Liu, Yanjian Peng, Xiren Zhang, Zhihao Ning and Dingzhong Fan
Technologies 2025, 13(8), 327; https://doi.org/10.3390/technologies13080327 - 31 Jul 2025
Viewed by 99
Abstract
High penetration of photovoltaic (PV) generation presents new challenges for voltage regulation in distribution networks (DNs), primarily due to output intermittency and constrained reactive power capabilities. This paper introduces a distributed voltage control method leveraging reactive power compensation from PV inverters. Instead of [...] Read more.
High penetration of photovoltaic (PV) generation presents new challenges for voltage regulation in distribution networks (DNs), primarily due to output intermittency and constrained reactive power capabilities. This paper introduces a distributed voltage control method leveraging reactive power compensation from PV inverters. Instead of relying on centralized computation, the proposed method allows each inverter to make local decisions using real-time voltage measurements and delayed communication with neighboring PV nodes. To account for practical asynchronous communication and feedback delay, a Distributed Online Primal–Dual Push–Sum (DOPP) algorithm that integrates a fixed-step delay model into the push–sum coordination framework is developed. Through extensive case studies on a modified IEEE 123-bus system, it has been demonstrated that the proposed method maintains robust performance under both static and dynamic scenarios, even in the presence of fixed feedback delays. Specifically, in static scenarios, the proposed strategy rapidly eliminates voltage violations within 50–100 iterations, effectively regulating all nodal voltages into the acceptable range of [0.95, 1.05] p.u. even under feedback delays with a delay step of 10. In dynamic scenarios, the proposed strategy ensures 100% voltage compliance across all nodes, demonstrating superior voltage regulation and reactive power coordination performance over conventional droop and incremental control approaches. Full article
19 pages, 2913 KiB  
Article
Radiation Mapping: A Gaussian Multi-Kernel Weighting Method for Source Investigation in Disaster Scenarios
by Songbai Zhang, Qi Liu, Jie Chen, Yujin Cao and Guoqing Wang
Sensors 2025, 25(15), 4736; https://doi.org/10.3390/s25154736 - 31 Jul 2025
Viewed by 142
Abstract
Structural collapses caused by accidents or disasters could create unexpected radiation shielding, resulting in sharp gradients within the radiation field. Traditional radiation mapping methods often fail to accurately capture these complex variations, making the rapid and precise localization of radiation sources a significant [...] Read more.
Structural collapses caused by accidents or disasters could create unexpected radiation shielding, resulting in sharp gradients within the radiation field. Traditional radiation mapping methods often fail to accurately capture these complex variations, making the rapid and precise localization of radiation sources a significant challenge in emergency response scenarios. To address this issue, based on standard Gaussian process regression (GPR) models that primarily utilize a single Gaussian kernel to reflect the inverse-square law in free space, a novel multi-kernel Gaussian process regression (MK-GPR) model is proposed for high-fidelity radiation mapping in environments with physical obstructions. MK-GPR integrates two additional kernel functions with adaptive weighting: one models the attenuation characteristics of intervening materials, and the other captures the energy-dependent penetration behavior of radiation. To validate the model, gamma-ray distributions in complex, shielded environments were simulated using GEometry ANd Tracking 4 (Geant4). Compared with conventional methods, including linear interpolation, nearest-neighbor interpolation, and standard GPR, MK-GPR demonstrated substantial improvements in key evaluation metrics, such as MSE, RMSE, and MAE. Notably, the coefficient of determination (R2) increased to 0.937. For practical deployment, the optimized MK-GPR model was deployed to an RK-3588 edge computing platform and integrated into a mobile robot equipped with a NaI(Tl) detector. Field experiments confirmed the system’s ability to accurately map radiation fields and localize gamma sources. When combined with SLAM, the system achieved localization errors of 10 cm for single sources and 15 cm for dual sources. These results highlight the potential of the proposed approach as an effective and deployable solution for radiation source investigation in post-disaster environments. Full article
(This article belongs to the Section Navigation and Positioning)
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19 pages, 3436 KiB  
Article
An Improved Wind Power Forecasting Model Considering Peak Fluctuations
by Shengjie Yang, Jie Tang, Lun Ye, Jiangang Liu and Wenjun Zhao
Electronics 2025, 14(15), 3050; https://doi.org/10.3390/electronics14153050 - 30 Jul 2025
Viewed by 189
Abstract
Wind power output sequences exhibit strong randomness and intermittency characteristics; traditional single forecasting models struggle to capture the internal features of sequences and are highly susceptible to interference from high-frequency noise and predictive accuracy is still notably poor at the peaks where the [...] Read more.
Wind power output sequences exhibit strong randomness and intermittency characteristics; traditional single forecasting models struggle to capture the internal features of sequences and are highly susceptible to interference from high-frequency noise and predictive accuracy is still notably poor at the peaks where the power curve undergoes abrupt changes. To address the poor fitting at peaks, a short-term wind power forecasting method based on the improved Informer model is proposed. First, the temporal convolutional network (TCN) is introduced to enhance the model’s ability to capture regional segment features along the temporal dimension, enhancing the model’s receptive field to address wind power fluctuation under varying environmental conditions. Next, a discrete cosine transform (DCT) is employed for adaptive modeling of frequency dependencies between channels, converting the time series data into frequency domain representations to extract its frequency features. These frequency domain features are then weighted using a channel attention mechanism to improve the model’s ability to capture peak features and resist noise interference. Finally, the Informer generative decoder is used to output the power prediction results, this enables the model to simultaneously leverage neighboring temporal segment features and long-range inter-temporal dependencies for future wind-power prediction, thereby substantially improving the fitting accuracy at power-curve peaks. Experimental results validate the effectiveness and practicality of the proposed model; compared with other models, the proposed approach reduces MAE by 9.14–42.31% and RMSE by 12.57–47.59%. Full article
(This article belongs to the Special Issue Digital Intelligence Technology and Applications)
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18 pages, 1777 KiB  
Article
Machine Learning in Sensory Analysis of Mead—A Case Study: Ensembles of Classifiers
by Krzysztof Przybył, Daria Cicha-Wojciechowicz, Natalia Drabińska and Małgorzata Anna Majcher
Molecules 2025, 30(15), 3199; https://doi.org/10.3390/molecules30153199 - 30 Jul 2025
Viewed by 165
Abstract
The aim was to explore using machine learning (including cluster mapping and k-means methods) to classify types of mead based on sensory analysis and aromatic compounds. Machine learning is a modern tool that helps with detailed analysis, especially because verifying aromatic compounds is [...] Read more.
The aim was to explore using machine learning (including cluster mapping and k-means methods) to classify types of mead based on sensory analysis and aromatic compounds. Machine learning is a modern tool that helps with detailed analysis, especially because verifying aromatic compounds is challenging. In the first stage, a cluster map analysis was conducted, allowing for the exploratory identification of the most characteristic features of mead. Based on this, k-means clustering was performed to evaluate how well the identified sensory features align with logically consistent groups of observations. In the next stage, experiments were carried out to classify the type of mead using algorithms such as Random Forest (RF), adaptive boosting (AdaBoost), Bootstrap aggregation (Bagging), K-Nearest Neighbors (KNN), and Decision Tree (DT). The analysis revealed that the RF and KNN algorithms were the most effective in classifying mead based on sensory characteristics, achieving the highest accuracy. In contrast, the AdaBoost algorithm consistently produced the lowest accuracy results. However, the Decision Tree algorithm achieved the highest accuracy value (0.909), demonstrating its potential for precise classification based on aroma characteristics. The error matrix analysis also indicated that acacia mead was easier for the algorithms to identify than tilia or buckwheat mead. The results show the potential of combining an exploratory approach (cluster map with the k-means method) with machine learning. It is also important to focus on selecting and optimizing classification models used in practice because, as the results so far indicate, choosing the right algorithm greatly affects the success of mead identification. Full article
(This article belongs to the Special Issue Analytical Technologies and Intelligent Applications in Future Food)
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14 pages, 1657 KiB  
Article
How Do the Surroundings of the C-NO2 Fragment Affect the Mechanical Sensitivity of Trinitroaromatic Molecules? Evidence from Crystal Structures and Ab Initio Calculations
by Danijela S. Kretić, Aleksandra B. Đunović, Dragan B. Ninković and Dušan Ž. Veljković
Crystals 2025, 15(8), 692; https://doi.org/10.3390/cryst15080692 - 30 Jul 2025
Viewed by 202
Abstract
The dissociation of the C-NO2 bond is the initial step in the process of the detonation of nitroaromatic explosives. The strength of the C-NO2 bond is significantly influenced by the relative position of the nitro group with respect to the aromatic [...] Read more.
The dissociation of the C-NO2 bond is the initial step in the process of the detonation of nitroaromatic explosives. The strength of the C-NO2 bond is significantly influenced by the relative position of the nitro group with respect to the aromatic ring plane since the planar arrangement enables the delocalization of electron density, which strengthens this bond. In this study, we have combined a statistical analysis of geometrical parameters extracted from crystal structures of trinitroaromatic molecules with ab initio calculations of non-covalent index plots and Wiberg bond index values for selected trinitroaromatic molecules to elucidate the influence of nearby substituents on the relative position of nitro groups with respect to the aromatic ring plane. The results of the analysis showed that neighboring substituents have a significant impact on the geometry of nitro groups. The results also showed that this influence arises from the repulsive interaction of voluminous substituents, attractive non-covalent contacts, and the electronic effects of substituents. Full article
(This article belongs to the Section Organic Crystalline Materials)
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24 pages, 3726 KiB  
Article
Telemedicine-Supported CPAP Therapy in Patients with Obstructive Sleep Apnea: Association with Treatment Adherence and Clinical Outcomes
by Norbert Wellmann, Versavia Maria Ancusa, Monica Steluta Marc, Ana Adriana Trusculescu, Camelia Corina Pescaru, Flavia Gabriela Martis, Ioana Ciortea, Alexandru Florian Crisan, Adelina Maritescu, Madalina Alexandra Balica and Ovidiu Fira-Mladinescu
J. Clin. Med. 2025, 14(15), 5339; https://doi.org/10.3390/jcm14155339 - 29 Jul 2025
Viewed by 205
Abstract
Background/Objectives: Obstructive sleep apnea (OSA) is a highly prevalent disorder that significantly impacts quality of life and daily functioning. While continuous positive airway pressure (CPAP) therapy is effective, long-term adherence remains a challenge. This single-arm observational study aimed to evaluate clinical outcomes and [...] Read more.
Background/Objectives: Obstructive sleep apnea (OSA) is a highly prevalent disorder that significantly impacts quality of life and daily functioning. While continuous positive airway pressure (CPAP) therapy is effective, long-term adherence remains a challenge. This single-arm observational study aimed to evaluate clinical outcomes and adherence patterns during telemedicine-supported CPAP therapy and identify distinct phenotypic response clusters in Romanian patients with OSA. Methods: This prospective observational study included 86 adults diagnosed with OSA, treated with ResMed Auto CPAP devices at “Victor Babeș” University Hospital in Timișoara, Romania. All patients were remotely monitored via the AirView™ platform and received monthly telephone interventions to promote adherence when necessary. Clinical outcomes were assessed through objective telemonitoring data. K-means clustering and t-distributed stochastic neighbor embedding (t-SNE) were employed to explore phenotypic response patterns. Results: During telemedicine-supported CPAP therapy, significant clinical improvements were observed. The apnea–hypopnea index (AHI) decreased from 42.0 ± 21.1 to 1.9 ± 1.3 events/hour. CPAP adherence improved from 75.5% to 90.5% over six months. Average daily usage increased from 348.4 ± 85.8 to 384.2 ± 65.2 min. However, post hoc analysis revealed significant concerns about the validity of self-reported psychological improvements. Self-esteem changes showed negligible correlation with objective clinical measures (r < 0.2, all p > 0.1), with only 3.3% of variance being explained by measurable therapeutic factors (R2 = 0.033). Clustering analysis identified four distinct adherence and outcome profiles, yet paradoxically, patients with lower adherence showed greater self-esteem improvements, contradicting therapeutic causation. Conclusions: Telemedicine-supported CPAP therapy with structured monthly interventions was associated with substantial clinical improvements, including excellent AHI reduction (22-fold) and high adherence rates (+15% after 6 months). Data-driven phenotyping successfully identified distinct patient response profiles, supporting personalized management approaches. However, the single-arm design prevents definitive attribution of improvements to telemonitoring versus natural adaptation or placebo effects. Self-reported psychological outcomes showed concerning patterns suggesting predominant placebo responses rather than therapeutic benefits. While the overall findings demonstrate the potential value of structured telemonitoring for objective CPAP outcomes, controlled trials are essential to establishing true therapeutic efficacy and distinguishing intervention effects from measurement bias. Full article
(This article belongs to the Special Issue Advances in Pulmonary Disease Management and Innovation in Treatment)
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