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17 pages, 1191 KiB  
Article
The Effects of Group Fitness Programs Zumba and MoFit on Body Composition Parameters in Women
by Armin Zećirović, Dejan Ćeremidžić, Aleksandar Joksimović, Tatjana Ćeremidžić, Dina Joksimović, Nikola Aksović, Lazar Toskić, Cristian-Corneliu Dragoi, Vasile Cătălin Ciocan, Anghel Mihaela, Tatiana Dobrescu and Daniel-Lucian Dobreci
Life 2025, 15(8), 1225; https://doi.org/10.3390/life15081225 - 3 Aug 2025
Viewed by 53
Abstract
(1) Background: Physical inactivity is a major public health concern in modern society. Group fitness programs are widely used to promote physical activity, combining choreographed movements with various dance steps and music. This study aimed to examine the effects of Zumba and MoFit [...] Read more.
(1) Background: Physical inactivity is a major public health concern in modern society. Group fitness programs are widely used to promote physical activity, combining choreographed movements with various dance steps and music. This study aimed to examine the effects of Zumba and MoFit group fitness programs on body composition parameters in women. (2) Methods: The study included 98 female participants (Mean age = 27.8 ± 2.9 years), divided into three groups: E1 (n = 33), which followed the experimental Zumba program; E2 (n = 31), which followed the experimental MoFit program; and a control group (n = 34), which continued with their usual daily activities for 10 weeks. Body composition was assessed using 14 variables measured with the InBody 270 analyser. Statistical analyses included paired t-tests, MANCOVA, and ANCOVA. (3) Results: The findings confirmed the positive effects of both group fitness programs on most body composition parameters in women (p < 0.001). However, Bonferroni post hoc test results indicated that the Zumba program led to significantly greater improvements in most body composition variables compared to the MoFit program. (4) Conclusions: Both Zumba and MoFit programs were effective in reducing body fat, increasing muscle mass, total body water, and mineral content, whereas the control group did not achieve positive changes. Full article
(This article belongs to the Section Physiology and Pathology)
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16 pages, 2388 KiB  
Article
Evaluating Lumbar Biomechanics for Work-Related Musculoskeletal Disorders at Varying Working Heights During Wall Construction Tasks
by Md. Sumon Rahman, Tatsuru Yazaki, Takanori Chihara and Jiro Sakamoto
Biomechanics 2025, 5(3), 58; https://doi.org/10.3390/biomechanics5030058 - 3 Aug 2025
Viewed by 53
Abstract
Objectives: The aim of this study was to evaluate the impact of four working heights on lumbar biomechanics during wall construction tasks, focusing on work-related musculoskeletal disorders (WMSDs). Methods: Fifteen young male participants performed simulated mortar-spreading and bricklaying tasks while actual [...] Read more.
Objectives: The aim of this study was to evaluate the impact of four working heights on lumbar biomechanics during wall construction tasks, focusing on work-related musculoskeletal disorders (WMSDs). Methods: Fifteen young male participants performed simulated mortar-spreading and bricklaying tasks while actual body movements were recorded using Inertial Measurement Unit (IMU) sensors. Muscle activities of the lumbar erector spinae (ES), quadratus lumborum (QL), multifidus (MF), gluteus maximus (GM), and iliopsoas (IL) were estimated using a 3D musculoskeletal (MSK) model and measured via surface electromyography (sEMG). The analysis of variance (ANOVA) test was conducted to identify the significant differences in muscle activities across four working heights (i.e., foot, knee, waist, and shoulder). Results: Findings showed that working at foot-level height resulted in the highest muscle activity (7.6% to 40.6% increase), particularly in the ES and QL muscles, indicating an increased risk of WMSDs. The activities of the ES, MF, and GM muscles were statistically significant across both tasks and all working heights (p < 0.01). Conclusions: Both MSK and sEMG analyses indicated significantly lower muscle activities at knee and waist heights, suggesting these as the best working positions (47 cm to 107 cm) for minimizing the risk of WMSDs. Conversely, working at foot and shoulder heights was identified as a significant risk factor for WMSDs. Additionally, the similar trends observed between MSK simulations and sEMG data suggest that MSK modeling can effectively substitute for sEMG in future studies. These findings provide valuable insights into ergonomic work positioning to reduce WMSD risks among wall construction workers. Full article
(This article belongs to the Section Tissue and Vascular Biomechanics)
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10 pages, 621 KiB  
Review
Optimizing Hip Abductor Strengthening for Lower Extremity Rehabilitation: A Narrative Review on the Role of Monster Walk and Lateral Band Walk
by Ángel González-de-la-Flor
J. Funct. Morphol. Kinesiol. 2025, 10(3), 294; https://doi.org/10.3390/jfmk10030294 - 30 Jul 2025
Viewed by 379
Abstract
Introduction: Hip abductor strength is essential for pelvic stability, lower limb alignment, and injury prevention. Weaknesses of the gluteus medius and minimus contribute to various musculoskeletal conditions. Lateral band walks and monster walks are elastic resistance exercises commonly used to target the [...] Read more.
Introduction: Hip abductor strength is essential for pelvic stability, lower limb alignment, and injury prevention. Weaknesses of the gluteus medius and minimus contribute to various musculoskeletal conditions. Lateral band walks and monster walks are elastic resistance exercises commonly used to target the hip abductors and external rotators in functional, weight-bearing tasks. Therefore, the aim was to summarize the current evidence on the biomechanics, muscle activation, and clinical applications of lateral and monster band walks. Methods: This narrative review was conducted following the SANRA guideline. A comprehensive literature search was performed across PubMed, Scopus, Web of Science, and SPORTDiscus up to April 2025. Studies on the biomechanics, electromyography, and clinical applications of lateral band walks and monster walks were included, alongside relevant evidence on hip abductor strengthening. Results: A total of 13 studies were included in the review, of which 4 specifically investigated lateral band walk and/or monster walk exercises. Lateral and monster walks elicit moderate to high activation of the gluteus medius and maximus, especially when performed with the band at the ankles or forefeet and in a semi-squat posture. This technique minimizes compensation from the tensor fasciae latae and promotes selective gluteal recruitment. Proper execution requires control of the trunk and pelvis, optimal squat depth, and consistent band tension. Anatomical factors (e.g., femoral torsion), sex differences, and postural variations may influence movement quality and necessitate tailored instruction. Full article
(This article belongs to the Special Issue Biomechanical Analysis in Physical Activity and Sports—2nd Edition)
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15 pages, 2397 KiB  
Article
Case Series and Literature Review on Botulinum Toxin Efficacy in Axial Extensor Truncal Dystonia
by Jarosław Sławek, Iga Alicja Łobińska, Michał Schinwelski, Joanna Kopcewicz-Wiśniewska and Anna Castagna
Toxins 2025, 17(8), 375; https://doi.org/10.3390/toxins17080375 - 29 Jul 2025
Viewed by 282
Abstract
Axial truncal dystonia can present as either flexion or extension, often with a tendency toward lateral movement. Flexion dystonia is more common and may represent a clinical spectrum associated with parkinsonism. In contrast, extensor trunk dystonia is less frequent and exhibits a diverse [...] Read more.
Axial truncal dystonia can present as either flexion or extension, often with a tendency toward lateral movement. Flexion dystonia is more common and may represent a clinical spectrum associated with parkinsonism. In contrast, extensor trunk dystonia is less frequent and exhibits a diverse range of causes. In this paper, we reviewed the literature on axial extensor trunk dystonia. We identified 11 studies involving 49 patients, of which only 10 had idiopathic trunk dystonia. Treatment with botulinum neurotoxin A (BoNT/A) emerged as the most effective therapy; however, many studies did not provide detailed descriptions of the treatment (4/11) and follow-up periods were not specified or short term (up to one–two years). We present four new, well-documented patients with the idiopathic form of extensor trunk dystonia who were treated with BoNT/A with moderate to significant effect according to Global Clinical Impression scale (GCI) and Burke-Fahn-Marsden (BFM) dystonia scale. These cases include long-term follow-up for three patients, all without any adverse events. While the diagnostic process and treatment can be challenging, we recommend using BoNT/A with adjusted doses tailored to the appropriate muscle groups as a first-line treatment. Full article
(This article belongs to the Special Issue Advances in the Treatment of Movement Disorders with Botulinum Toxins)
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16 pages, 5818 KiB  
Case Report
Novel Sonoguided Digital Palpation and Ultrasound-Guided Hydrodissection of the Long Thoracic Nerve for Managing Serratus Anterior Muscle Pain Syndrome: A Case Report with Technical Details
by Nunung Nugroho, King Hei Stanley Lam, Theodore Tandiono, Teinny Suryadi, Anwar Suhaimi, Wahida Ratnawati, Daniel Chiung-Jui Su, Yonghyun Yoon and Kenneth Dean Reeves
Diagnostics 2025, 15(15), 1891; https://doi.org/10.3390/diagnostics15151891 - 28 Jul 2025
Viewed by 991
Abstract
Background and Clinical Significance: Serratus Anterior Muscle Pain Syndrome (SAMPS) is an underdiagnosed cause of anterior chest wall pain, often attributed to myofascial trigger points of the serratus anterior muscle (SAM) or dysfunction of the Long Thoracic Nerve (LTN), leading to significant disability [...] Read more.
Background and Clinical Significance: Serratus Anterior Muscle Pain Syndrome (SAMPS) is an underdiagnosed cause of anterior chest wall pain, often attributed to myofascial trigger points of the serratus anterior muscle (SAM) or dysfunction of the Long Thoracic Nerve (LTN), leading to significant disability and affecting ipsilateral upper limb movement and quality of life. Current diagnosis relies on exclusion and physical examination, with limited treatment options beyond conservative approaches. This case report presents a novel approach to chronic SAMPS, successfully diagnosed using Sonoguided Digital Palpation (SDP) and treated with ultrasound-guided hydrodissection of the LTN using 5% dextrose in water (D5W) without local anesthetic (LA), in a patient where conventional treatments had failed. Case Presentation: A 72-year-old male presented with a three-year history of persistent left chest pain radiating to the upper back, exacerbated by activity and mimicking cardiac pain. His medical history included two percutaneous coronary interventions. Physical examination revealed tenderness along the anterior axillary line and a positive hyperirritable spot at the mid axillary line at the 5th rib level. SDP was used to visualize the serratus anterior fascia (SAF) and LTN, and to reproduce the patient’s concordant pain by palpating the LTN. Ultrasound-guided hydrodissection of the LTN was then performed using 20–30cc of D5W without LA to separate the nerve from the surrounding tissues, employing a “fascial unzipping” technique. The patient reported immediate pain relief post-procedure, with the pain reducing from 9/10 to 1/10 on the Numeric Rating Scale (NRS), and sustained relief and functional improvement at the 12-month follow-up. Conclusions: Sonoguided Digital Palpation (SDP) of the LTN can serve as a valuable diagnostic adjunct for visualizing and diagnosing SAMPS. Ultrasound-guided hydrodissection of the LTN with D5W without LA may provide a promising and safe treatment option for patients with chronic SAMPS refractory to conservative management, resulting in rapid and sustained pain relief. Further research, including controlled trials, is warranted to evaluate the long-term efficacy and generalizability of these findings and to compare D5W to other injectates. Full article
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14 pages, 960 KiB  
Article
Backward Chaining Method for Teaching Long-Term Care Residents to Stand Up from the Floor: A Pilot Randomized Controlled Trial
by Anna Zsófia Kubik, Zsigmond Gyombolai, András Simon and Éva Kovács
J. Clin. Med. 2025, 14(15), 5293; https://doi.org/10.3390/jcm14155293 - 26 Jul 2025
Viewed by 387
Abstract
Objectives: Older adults who worry about not being able to stand up from the floor after a fall, reduce their physical activity, which leads to a higher risk of falling. The Backward Chaining Method (BCM) was developed specifically for this population to [...] Read more.
Objectives: Older adults who worry about not being able to stand up from the floor after a fall, reduce their physical activity, which leads to a higher risk of falling. The Backward Chaining Method (BCM) was developed specifically for this population to safely teach and practice the movement sequence required to stand up from the floor. Our aim is to evaluate the effectiveness of using the BCM to teach older adults how to stand up from the floor, and to determine whether this training has an impact on functional mobility, muscle strength, fear of falling, and life-space mobility. Methods: A total of 26 residents of a long-term care facility were randomly allocated to two groups. Residents in the intervention group (IG, n = 13) participated in a seven-week training program to learn how to stand up from the floor with BCM, in addition to the usual care generally offered in long-term care facilities. The participants in the control group (CG, n = 13) received the usual care alone. The primary outcome measure was functional mobility, assessed by the Timed Up and Go test. Secondary outcome measures included functional lower limb strength, grip strength, fear of falling, and life-space mobility. The outcomes were measured at baseline and after the seven-week intervention period. Results: We found no significant between-group differences in functional mobility, lower limb strength and grip strength; however, IG subjects demonstrated significantly lower fear of falling scores, and significantly higher life-space mobility and independent life-space mobility scores compared to CG subjects after the training program. Conclusions: This study demonstrates that the Backward Chaining Method is a feasible, well-tolerated intervention in a long-term care setting and it may have meaningful benefits, particularly in lessening fear of falling and improving life-space mobility and independent life-space mobility when incorporated into the usual physiotherapy interventions. Full article
(This article belongs to the Section Geriatric Medicine)
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10 pages, 409 KiB  
Article
Electromyographic Analysis of Lower Limb Muscles During Multi-Joint Eccentric Isokinetic Exercise Using the Eccentron Dynamometer
by Brennan J. Thompson, Merrill Ward, Brayden Worley and Talin Louder
Appl. Sci. 2025, 15(15), 8280; https://doi.org/10.3390/app15158280 - 25 Jul 2025
Viewed by 223
Abstract
Eccentric muscle actions are integral to human movement, rehabilitation, and performance training due to their characteristic high force output (overload) and low energy cost and perceived exertion. Despite the growing use of eccentric devices, a gap in the research exists exploring multi-muscle activation [...] Read more.
Eccentric muscle actions are integral to human movement, rehabilitation, and performance training due to their characteristic high force output (overload) and low energy cost and perceived exertion. Despite the growing use of eccentric devices, a gap in the research exists exploring multi-muscle activation profiles during multi-joint eccentric-only, isokinetic exercise. This study aimed to quantify and compare surface electromyographic (EMG) activity of four leg muscles—vastus lateralis (VL), tibialis anterior (TA), biceps femoris (BF), and medial gastrocnemius (GM)—during a standardized (isokinetic) submaximal eccentric multi-joint exercise using the Eccentron dynamometer. Eighteen healthy adults performed eccentric exercise at 40% of their maximal eccentric strength. Surface EMG data were analyzed using root mean square (RMS) and integrated EMG (iEMG) variables. Repeated-measures ANOVAs and effect sizes (ES) were used to evaluate within-subject differences across muscles. Results showed significantly greater activation in the VL compared to all other muscles (p < 0.05; and ES of 1.28–3.17 versus all other muscles), with the TA also demonstrating higher activation than the BF (p < 0.05). The BF exhibited the lowest activation, suggesting limited hamstring engagement. These findings highlight the effectiveness of the multi-joint isokinetic eccentric leg press movement (via an Eccentron machine) in targeting the quadriceps and dorsiflexors, while indicating the possible need for supplementary hamstring and plantar flexor exercises when aiming for a comprehensive lower body training routine. This study provides important insights for optimizing eccentric training protocols and rehabilitation strategies. Full article
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14 pages, 285 KiB  
Article
Effects of Stretching and Resistance Training on Psychophysical Awareness: A Pilot Study
by Giovanni Esposito, Rosario Ceruso, Pietro Luigi Invernizzi, Vincenzo Manzi and Gaetano Raiola
Appl. Sci. 2025, 15(15), 8259; https://doi.org/10.3390/app15158259 - 24 Jul 2025
Viewed by 286
Abstract
Muscle–joint flexibility is defined as the ability of a muscle to stretch in a controlled manner, allowing a wide range of movement at the joints. While numerous methodologies exist for improving flexibility, few studies have investigated the role of athletes’ perceptual processes and [...] Read more.
Muscle–joint flexibility is defined as the ability of a muscle to stretch in a controlled manner, allowing a wide range of movement at the joints. While numerous methodologies exist for improving flexibility, few studies have investigated the role of athletes’ perceptual processes and awareness related to their own body and movement control during such training. In this pilot study, we explored how two different training protocols—static and dynamic stretching (control group, CON) and multi-joint resistance training (experimental group, EXP)—influence both flexibility and psychophysical awareness, understood as a multidimensional construct involving perceived flexibility improvements, self-assessed control over exercise execution, and cognitive-emotional responses such as engagement, motivation, and satisfaction during physical effort. The study involved 24 male amateur track-and-field athletes (mean age 23 ± 2.5 years), randomized into two equal groups. Over 12 weeks, both groups trained three times per week. Flexibility was assessed using the Sit and Reach Test at three time points (pre-, mid-, and post-intervention). A 2 × 3 mixed ANOVA revealed a significant group × time interaction (F = 20.17, p < 0.001), with the EXP group showing greater improvements than the CON group. In the EXP group, Sit and Reach scores increased from pre = 28.55 cm (SD = 4.91) to mid = 29.39 cm (SD = 4.67) and post = 29.48 cm (SD = 4.91), with a significant difference between pre and post (p = 0.01; d = 0.35). The CON group showed minimal changes, with scores of pre = 28.66 cm (SD = 4.92), mid = 28.76 cm (SD = 5.03), and post = 28.84 cm (SD = 5.10), and no significant difference between pre and post (p = 0.20; d = 0.04). Psychophysical awareness was assessed using a custom questionnaire structured on a 5-point Likert scale, with items addressing perception of flexibility, motor control, and exercise-related bodily sensations. The questionnaire showed excellent internal consistency (Cronbach’s α = 0.92). Within the EXP group, psychophysical awareness increased significantly (from 3.50 to 4.17; p = 0.01; d = 0.38), while no significant change occurred in the CON group (p = 0.16). Post-hoc power analysis confirmed small to moderate effect sizes within the EXP group, although between-group differences lacked sufficient statistical power. These results suggest that resistance training may improve flexibility and concurrently enhance athletes’ psychophysical self-awareness more effectively than traditional stretching. Such findings offer practical implications for coaches seeking to optimize flexibility training by integrating alternative methods that promote both physical and perceptual adaptations. Full article
(This article belongs to the Section Applied Biosciences and Bioengineering)
12 pages, 262 KiB  
Article
Sex Differences in Bench Press Strength and Power: A Velocity-Based Analysis Adjusted for Body Composition
by Olga López-Torres, Raúl Nieto-Acevedo, Amelia Guadalupe-Grau and Valentín Emilio Fernández Elías
J. Funct. Morphol. Kinesiol. 2025, 10(3), 284; https://doi.org/10.3390/jfmk10030284 - 24 Jul 2025
Viewed by 749
Abstract
Background: Resistance training (RT) promotes muscle hypertrophy and strength gains in both men and women. However, sex differences in neuromuscular performance, muscle fiber composition, and the hormonal environment influence strength and power adaptations. While men generally exhibit greater absolute and relative strength, it [...] Read more.
Background: Resistance training (RT) promotes muscle hypertrophy and strength gains in both men and women. However, sex differences in neuromuscular performance, muscle fiber composition, and the hormonal environment influence strength and power adaptations. While men generally exhibit greater absolute and relative strength, it remains unclear to what extent these differences persist across various load intensities. A better understanding of sex-specific strength and power profiles may help optimize training strategies. The aim of this study was to compare strength and power performance during the bench press exercise in physically active males and females, relative to body mass and fat-free mass (FFM). Methods: Twenty-nine physically active individuals (16 men: 21.3 ± 4.1 years, 13 women: 22.6 ± 4.9 years) performed a one-repetition maximum (1RM) test and an incremental velocity-based assessment at 45%, 55%, 65%, 75%, and 85% of the 1RM using a Smith machine. The barbell velocity was measured via a linear transducer, with the mean propulsive velocity (MPV) recorded for each load. Power-related variables (e.g., peak force [F0], maximal velocity [V0], and maximal power [Pmax]) were analyzed. To account for differences in body composition, data were adjusted for body mass and FFM. Results: Men exhibited significantly greater strength and power than women across most loads when adjusted for both body mass and fat-free mass (FFM) (p < 0.05). These differences were particularly pronounced when normalized to FFM (45–75%1RM; p = 0.001–0.031), with large effect sizes observed (ηp2 = 0.185–0.383). Notably, sex differences in mean propulsive velocity (MPV) disappeared at 85%1RM (p = 0.208; ηp2 = 0.06), suggesting that maximal neuromuscular recruitment may minimize sex-related disparities at higher intensities. Furthermore, men demonstrated significantly higher values in six of the seven power-related variables, with no significant differences in the %1RM required to achieve an optimal power output. Conclusions: These findings confirm that men exhibit greater strength and power than women, even after adjusting for body composition. However, at high relative loads (≥85%1RM), sex differences in movement velocity appear to diminish, likely due to similar recruitment patterns of high-threshold motor units. These results highlight the importance of sex-specific resistance training programs, particularly in relation to load prescription and the application of velocity-based training methods. Full article
31 pages, 4621 KiB  
Perspective
Current Flow in Nerves and Mitochondria: An Electro-Osmotic Approach
by Robert S. Eisenberg
Biomolecules 2025, 15(8), 1063; https://doi.org/10.3390/biom15081063 - 22 Jul 2025
Viewed by 215
Abstract
The electrodynamics of current provide much of our technology, from telegraphs to the wired infrastructure powering the circuits of our electronic technology. Current flow is analyzed by its own rules that involve the Maxwell Ampere law and magnetism. Electrostatics does not involve magnetism, [...] Read more.
The electrodynamics of current provide much of our technology, from telegraphs to the wired infrastructure powering the circuits of our electronic technology. Current flow is analyzed by its own rules that involve the Maxwell Ampere law and magnetism. Electrostatics does not involve magnetism, and so current flow and electrodynamics cannot be derived from electrostatics. Practical considerations also prevent current flow from being analyzed one charge at a time. There are too many charges, and far too many interactions to allow computation. Current flow is essential in biology. Currents are carried by electrons in mitochondria in an electron transport chain. Currents are carried by ions in nerve and muscle cells. Currents everywhere follow the rules of current flow: Kirchhoff’s current law and its generalizations. The importance of electron and proton flows in generating ATP was discovered long ago but they were not analyzed as electrical currents. The flow of protons and transport of electrons form circuits that must be analyzed by Kirchhoff’s law. A chemiosmotic theory that ignores the laws of current flow is incorrect physics. Circuit analysis is easily applied to short systems like mitochondria that have just one internal electrical potential in the form of the Hodgkin Huxley Katz (HHK) equation. The HHK equation combined with classical descriptions of chemical reactions forms a computable model of cytochrome c oxidase, part of the electron transport chain. The proton motive force is included as just one of the components of the total electrochemical potential. Circuit analysis includes its role just as it includes the role of any other ionic current. Current laws are now needed to analyze the flow of electrons and protons, as they generate ATP in mitochondria and chloroplasts. Chemiosmotic theory must be replaced by an electro-osmotic theory of ATP production that conforms to the Maxwell Ampere equation of electrodynamics while including proton movement and the proton motive force. Full article
(This article belongs to the Special Issue Advances in Cellular Biophysics: Transport and Mechanics)
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19 pages, 2191 KiB  
Article
In Vivo Study on 3D-Printed Polylactic Acid Nerve Tubes for Sciatic Nerve Injury Treatment
by Salih Kavuncu, Rauf Hamid and Ömer Faruk Sarıahmetoğlu
Polymers 2025, 17(14), 1992; https://doi.org/10.3390/polym17141992 - 21 Jul 2025
Viewed by 353
Abstract
Background/Objectives: Nerve injuries cause functional loss and psychosocial issues due to prolonged rehabilitation. Recently, 3D-modeled nerve conduits have been used to aid in surgical planning. This study investigated the impact of 3D-bioprinted PLA, chitosan, alginate, and collagen conduits on nerve regeneration in a [...] Read more.
Background/Objectives: Nerve injuries cause functional loss and psychosocial issues due to prolonged rehabilitation. Recently, 3D-modeled nerve conduits have been used to aid in surgical planning. This study investigated the impact of 3D-bioprinted PLA, chitosan, alginate, and collagen conduits on nerve regeneration in a rat sciatic nerve crush injury model. Methods: This study, conducted at Kütahya University of Health Sciences, involves 50 rats were divided into four groups: (1) sham-operated controls, (2) sciatic nerve injury without treatment, (3) injury treated with a PLA conduit, and (4) injury treated with 3D-printed tubes composed of chitosan and alginate. The procedures were performed, blood was collected, and the rats were sacrificed after two months. Weekly checks for infection, scar healing, and motor responses were performed. Results: Rats with nerve conduits showed less macroscopic scarring. Weekly assessments of motor nerve recovery showed no movement restrictions in limbs treated with PLA conduits, graft conduits, or conduits bridging retracted nerve stumps, based on responses to stimulus checks. An infection developed in the sciatic nerve and surrounding muscle tissue of one rat with a bio-graft conduit, prompting histopathological examination to investigate its cause. Conclusions: This proof-of-principle study demonstrates the feasibility of using 3D-printed biocompatible nerve conduits for peripheral nerve repair, providing a basis for future, more comprehensive investigations. Full article
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14 pages, 4344 KiB  
Article
Ultrasound-Based Morphological and Functional Assessment in Male CrossFit Athletes with Unilateral Subacromial Shoulder Pain: An Observational Study
by Fabien Guerineau, Ann Cools, Jaime Almazán-Polo, María Dolores Sosa-Reina, Vanesa Abuín-Porras, Cristian Baroa-Fernández, Pablo García-Ginés, Ana Román-Franganillo and Ángel González-de-la-Flor
Medicina 2025, 61(7), 1304; https://doi.org/10.3390/medicina61071304 - 19 Jul 2025
Viewed by 261
Abstract
Background and Objectives: CrossFit is a discipline involving a wide range of overhead movements performed at high intensity and under accumulated fatigue that predispose to a high risk of shoulder complex injuries. This study aimed to compare ultrasonographic findings between symptomatic and [...] Read more.
Background and Objectives: CrossFit is a discipline involving a wide range of overhead movements performed at high intensity and under accumulated fatigue that predispose to a high risk of shoulder complex injuries. This study aimed to compare ultrasonographic findings between symptomatic and asymptomatic shoulders in CrossFit athletes. Materials and Methods: A cross-sectional study was conducted to compare ultrasound parameters between the painful and non-painful shoulders in CrossFit athletes with unilateral subacromial shoulder pain. Assessed variables included subacromial subdeltoid bursa thickness, supraspinatus tendon thickness, the acromiohumeral distance, the coracoacromial ligament distance, the bicipital groove angle, cross-sectional area of the biceps brachii longus head tendon, as well as the serratus anterior and lower trapezius muscle thickness. Results: Twenty male CrossFit athletes (forty shoulders) with an average age of 25.70 ± 4.03 years participated in the study. A statistically significant increase was observed (p < 0.05) in the subacromial subdeltoid bursa thickness in the painful shoulder compared to the asymptomatic side. All other ultrasound parameters did not show statistically significant differences. Conclusions: Only subacromial subdeltoid bursa thickness differed significantly between sides. This isolated finding may not fully explain shoulder pain, which cannot be solely attributed to morphological changes. Further research is needed to determine the relationship between shoulder pain and ultrasound features in CrossFit athletes, as well as the role of ultrasound in predicting structural changes in pain conditions. Full article
(This article belongs to the Special Issue Recent Trends in Physical Therapy for Musculoskeletal Disorders)
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12 pages, 2851 KiB  
Article
Comparative Analysis of Mechanical Variables in Different Exercises Performed with a Rotational Inertial Device in Professional Soccer Players: A Pilot Study
by Álvaro Murillo-Ortiz, Luis Manuel Martínez-Aranda, Moisés Falces-Prieto, Samuel López-Mariscal, Francisco Javier Iglesias-García and Javier Raya-González
J. Funct. Morphol. Kinesiol. 2025, 10(3), 279; https://doi.org/10.3390/jfmk10030279 - 18 Jul 2025
Viewed by 323
Abstract
Background: Soccer performance is largely dependent on high-intensity, unilateral actions such as sprints, jumps, and changes of direction. These demands can lead to strength and power differences between limbs, highlighting the importance of individualised assessment in professional players. Rotational inertial devices offer a [...] Read more.
Background: Soccer performance is largely dependent on high-intensity, unilateral actions such as sprints, jumps, and changes of direction. These demands can lead to strength and power differences between limbs, highlighting the importance of individualised assessment in professional players. Rotational inertial devices offer a valuable method to evaluate and train these mechanical variables separately for each leg. The aim of this study was twofold: (a) to characterise the mechanical variables derived from several lower-body strength exercises performed on rotational inertial devices, all targeting the same muscle group; and (b) to compare the mechanical variables between the dominant and non-dominant leg for each exercise. Methods: Twenty-six male professional soccer players (age = 26.3 ± 5.1 years; height = 182.3 ± 0.6 cm; weight = 75.9 ± 5.9 kg; body mass index = 22.8 ± 1.1 kg/m2; fat mass percentage = 9.1 ± 0.6%; fat-free mass = 68.8 ± 5.3 kg), all belonging to the same professional Belgian team, voluntarily participated in this study. The players completed a single assessment session consisting of six unilateral exercises (i.e., quadriceps hip, hamstring knee, adductor, quadriceps knee, hamstring hip, and abductor). For each exercise, they performed two sets of eight repetitions with each leg (i.e., dominant and non-dominant) in a randomised order. Results: The quadriceps hip exercise resulted in higher mechanical values compared to the quadriceps knee exercise in both limbs (p < 0.004). Similarly, the hamstring hip exercise produced greater values across all variables and limbs (p < 0.004), except for peak force, where the hamstring knee exercise exhibited higher values (p < 0.004). The adductor exercise showed higher peak force values for the dominant limb (p < 0.004). The between-limb comparison revealed differences only in the abductor exercise (p < 0.004). Conclusions: These findings suggest the necessity of prioritising movement selection based on targeted outcomes, although it should be considered that the differences between limb differences are very limited. Full article
(This article belongs to the Special Issue Sports-Specific Conditioning: Techniques and Applications)
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14 pages, 8113 KiB  
Article
Cellular and Matrix Organisation of the Human Aortic Valve Interleaflet Triangles
by Najma Latif, Padmini Sarathchandra, Albaraa Al-Holy, Sanida Vaz, Adrian H. Chester and Magdi H. Yacoub
Biology 2025, 14(7), 863; https://doi.org/10.3390/biology14070863 - 16 Jul 2025
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Abstract
(1) Background: The sophisticated function of the aortic root relies on the coordinated movement of its constituent components. This study examines the extracellular components of the interleaflet triangles (ILTs) and characterises the cells that are present within this region of the aortic root. [...] Read more.
(1) Background: The sophisticated function of the aortic root relies on the coordinated movement of its constituent components. This study examines the extracellular components of the interleaflet triangles (ILTs) and characterises the cells that are present within this region of the aortic root. (2) Methods: A total of 10 human aortic valves and 6 porcine aortic valves were processed for immunohistochemical staining, scanning, and transmission electron microscopy. (3) Results: The three ILTs differed in size and macroscopic appearance. Each triangle comprised up to five distinct layers of tissue: an innermost endothelial layer, an inner elastin-rich layer, a thicker outer layer comprising densely packed layers of collagen and glycosaminoglycans, and an outer layer of intermingled myocardial and adipose tissue. A band of cells near the luminal surfaces of all ILTs expressed smooth muscle cell α-actin with variable expression of smooth muscle myosin heavy chain. In all the ILTs, there was evidence of neurofilament staining, indicating the presence of nerve fibres. (4) Conclusions: Each ILT is unique in its structure and organisation, with differing amounts of elastin and collagen, as well as myocardial, adipose, and fibrous content. The ILTs contain multiple cell types in varying abundance. Functional studies are required to determine the role of the different cells and their organisation in contributing to the sophisticated, dynamic behaviour of the aortic root. Full article
(This article belongs to the Section Cell Biology)
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31 pages, 40778 KiB  
Article
Crystal Organisation of Muscle Attachment Sites of Bivalved Marine Organisms: A Juxtaposition Between Brachiopod and Bivalved Mollusc Shells
by Sebastian Hoerl, Erika Griesshaber, Daniel Weller, Shahrouz Amini, Verena Häussermann, Maria A. Bitner, Klaus Achterhold, Franz Pfeiffer and Wolfgang W. Schmahl
Crystals 2025, 15(7), 649; https://doi.org/10.3390/cryst15070649 - 15 Jul 2025
Viewed by 249
Abstract
The movement of valves of bivalved invertebrates is enabled through the action of muscles and the interplay between the muscles and the hinge ligament. The muscles that move the valves attach to their internal surface. To promote the structural integrity at the mechanically [...] Read more.
The movement of valves of bivalved invertebrates is enabled through the action of muscles and the interplay between the muscles and the hinge ligament. The muscles that move the valves attach to their internal surface. To promote the structural integrity at the mechanically mismatched interfaces, a specific crystal microstructure and texture are present at the muscle attachment sites. These are different from the crystal microstructure and texture of the rest of the valves. We present here for modern two- and three-layered brachiopod shells (Magellania venosa, Liothyrella neozelanica and Gryphus vitreus) the mode of crystal organisation at sites of adductor and diductor muscle attachments (i) relative to the microstructure and texture that forms the other sections of the valves and (ii) relative to crystal organisation of muscle attachment sites of bivalved invertebrates of other phyla, namely, species of the class Bivalvia. We discuss similarities/differences in Ca-carbonate phase, microstructure and texture between rhynchonellate brachiopods and bivalves, and discuss whether the Ca-carbonate crystal organisation of muscle attachment sites is convergent for bivalved marine organisms. We show significant differences in muscle attachment site architecture and highlight the different structural solutions developed by nature for shells of marine organisms that serve the same purpose. Full article
(This article belongs to the Section Mineralogical Crystallography and Biomineralization)
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