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Search Results (1,237)

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Keywords = multilayer control

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19 pages, 2520 KiB  
Article
Research on a Blockchain-Based Quality and Safety Traceability System for Hymenopellis raphanipes
by Wei Xu, Hongyan Guo, Xingguo Zhang, Mingxia Lin and Pingzeng Liu
Sustainability 2025, 17(16), 7413; https://doi.org/10.3390/su17167413 (registering DOI) - 16 Aug 2025
Abstract
Hymenopellis raphanipes is a high-value edible fungus with a short shelf life and high perishability, which poses significant challenges for quality control and safety assurance throughout its supply chain. Ensuring effective traceability is essential for improving production management, strengthening consumer trust, and supporting [...] Read more.
Hymenopellis raphanipes is a high-value edible fungus with a short shelf life and high perishability, which poses significant challenges for quality control and safety assurance throughout its supply chain. Ensuring effective traceability is essential for improving production management, strengthening consumer trust, and supporting brand development. This study proposes a comprehensive traceability system tailored to the full lifecycle of Hymenopellis raphanipes, addressing the operational needs of producers and regulators alike. Through detailed analysis of the entire supply chain, from raw material intake, cultivation, and processing to logistics and sales, the system defines standardized traceability granularity and a unique hierarchical coding scheme. A multi-layered system architecture is designed, comprising a data acquisition layer, network transmission layer, storage management layer, service orchestration layer, business logic layer, and user interaction layer, ensuring modularity, scalability, and maintainability. To address performance bottlenecks in traditional systems, a multi-chain collaborative traceability model is introduced, integrating a mainchain–sidechain storage mechanism with an on-chain/off-chain hybrid management strategy. This approach effectively mitigates storage overhead and enhances response efficiency. Furthermore, data integrity is verified through hash-based validation, supporting high-throughput queries and reliable traceability. Experimental results from its real-world deployment demonstrate that the proposed system significantly outperforms traditional single-chain models in terms of query latency and throughput. The solution enhances data transparency and regulatory efficiency, promotes sustainable practices in green agricultural production, and offers a scalable reference model for the traceability of other high-value agricultural products. Full article
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20 pages, 2424 KiB  
Article
Predicting Vehicle-Engine-Radiated Noise Based on Bench Test and Machine Learning
by Ruijun Liu, Yingqi Yin, Yuming Peng and Xu Zheng
Machines 2025, 13(8), 724; https://doi.org/10.3390/machines13080724 - 15 Aug 2025
Abstract
As engines trend toward miniaturization, lightweight design, and higher power density, noise issues have become increasingly prominent, necessitating precise radiated noise prediction for effective noise control. This study develops a machine learning model based on surface vibration test data, which enhances the efficiency [...] Read more.
As engines trend toward miniaturization, lightweight design, and higher power density, noise issues have become increasingly prominent, necessitating precise radiated noise prediction for effective noise control. This study develops a machine learning model based on surface vibration test data, which enhances the efficiency of engine noise prediction and has the potential to serve as an alternative to traditional high-cost engine noise test methods. Experiments were conducted on a four-cylinder, four-stroke diesel engine, collecting surface vibration and radiated noise data under full-load conditions (1600–3000 r/min). Five prediction models were developed using support vector regression (SVR, including linear, polynomial, and radial basis function kernels), random forest regression, and multilayer perceptron, suitable for non-anechoic environments. The models were trained on time-domain and frequency-domain vibration data, with performance evaluated using the maximum absolute error, mean absolute error, and median absolute error. The results show that polynomial kernel SVR performs best in time domain modelling, with an average relative error of 0.10 and a prediction accuracy of up to 90%, which is 16% higher than that of MLP; the model does not require Fourier transform and principal component analysis, and the computational overhead is low, but it needs to collect data from multiple measurement points. The linear kernel SVR works best in frequency domain modelling, with an average relative error of 0.18 and a prediction accuracy of about 82%, which is suitable for single-point measurement scenarios with moderate accuracy requirements. Analysis of measurement points indicates optimal performance using data from the engine top between cylinders 3 and 4. This approach reduces reliance on costly anechoic facilities, providing practical value for noise control and design optimization. Full article
(This article belongs to the Special Issue Intelligent Applications in Mechanical Engineering)
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19 pages, 6692 KiB  
Article
A Deep Learning-Based Machine Vision System for Online Monitoring and Quality Evaluation During Multi-Layer Multi-Pass Welding
by Van Doi Truong, Yunfeng Wang, Chanhee Won and Jonghun Yoon
Sensors 2025, 25(16), 4997; https://doi.org/10.3390/s25164997 - 12 Aug 2025
Viewed by 175
Abstract
Multi-layer multi-pass welding plays an important role in manufacturing industries such as nuclear power plants, pressure vessel manufacturing, and ship building. However, distortion or welding defects are still challenges; therefore, welding monitoring and quality control are essential tasks for the dynamic adjustment of [...] Read more.
Multi-layer multi-pass welding plays an important role in manufacturing industries such as nuclear power plants, pressure vessel manufacturing, and ship building. However, distortion or welding defects are still challenges; therefore, welding monitoring and quality control are essential tasks for the dynamic adjustment of execution during welding. The aim was to propose a machine vision system for monitoring and surface quality evaluation during multi-pass welding using a line scanner and infrared camera sensors. The cross-section modelling based on the line scanner data enabled the measurement of distortion and dynamic control of the welding plan. Lack of fusion, porosity, and burn-through defects were intentionally generated by controlling welding parameters to construct a defect inspection dataset. To reduce the influence of material surface colour, the proposed normal map approach combined with a deep learning approach was applied for inspecting the surface defects on each layer, achieving a mean average precision of 0.88. In addition to monitoring the temperature of the weld pool, a burn-through defect detection algorithm was introduced to track welding status. The whole system was integrated into a graphical user interface to visualize the welding progress. This work provides a solid foundation for monitoring and potential for the further development of the automatic adaptive welding system in multi-layer multi-pass welding. Full article
(This article belongs to the Section Fault Diagnosis & Sensors)
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21 pages, 3053 KiB  
Article
Photovoltaic Digital Twins: Mathematical Modeling vs. Neural Networks for Energy Management in Smart Buildings
by Doroteya Dimitrova-Angelova, Juan F. González-González, Diego Carmona-Fernández and Miguel A. Jaramillo-Morán
Appl. Sci. 2025, 15(16), 8883; https://doi.org/10.3390/app15168883 - 12 Aug 2025
Viewed by 175
Abstract
Efficiently controlling and managing photovoltaic installations for self-consumption is key to making optimal use of these systems. The first step to achieving that control is modeling the generation of electricity by photovoltaic panels with digital twins. This paper presents an experimental evaluation of [...] Read more.
Efficiently controlling and managing photovoltaic installations for self-consumption is key to making optimal use of these systems. The first step to achieving that control is modeling the generation of electricity by photovoltaic panels with digital twins. This paper presents an experimental evaluation of four photovoltaic power prediction models in a real-world environment using high-resolution, annual data from a university facility. A mathematical model and three neural network models (MLP, LSTM, and GRU) are compared under standardized metrics. The results demonstrate that the Multilayer Perceptron (MLP) achieves the highest overall accuracy and seasonal consistency. It outperforms the other three models, particularly in scenarios where the relationships between meteorological variables and power generation are predominantly static. However, the mathematical model maintains a competitive performance in conditions of low variability, such as in the summer and autumn. The seasonal analysis reveals the importance of selecting and adjusting models according to operational and climatic contexts. This study’s main contribution is identifying the MLP as the most efficient option for implementing digital twins in photovoltaic installation control. This facilitates real-time monitoring, optimization, and predictive maintenance and contributes to smart, sustainable energy management in buildings to align with climate neutrality guidelines. Full article
(This article belongs to the Special Issue Applications in Neural and Symbolic Artificial Intelligence)
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19 pages, 3371 KiB  
Article
Prediction of Photovoltaic Module Characteristics by Machine Learning for Renewable Energy Applications
by Rafał Porowski, Robert Kowalik, Bartosz Szeląg, Diana Komendołowicz, Anita Białek, Agata Janaszek, Magdalena Piłat-Rożek, Ewa Łazuka and Tomasz Gorzelnik
Appl. Sci. 2025, 15(16), 8868; https://doi.org/10.3390/app15168868 - 11 Aug 2025
Viewed by 401
Abstract
Photovoltaic (PV) modules undergo comprehensive testing to validate their electrical and thermal properties prior to market entry. These evaluations consist of durability and efficiency tests performed under realistic outdoor conditions with natural climatic influences, as well as in controlled laboratory settings. The overall [...] Read more.
Photovoltaic (PV) modules undergo comprehensive testing to validate their electrical and thermal properties prior to market entry. These evaluations consist of durability and efficiency tests performed under realistic outdoor conditions with natural climatic influences, as well as in controlled laboratory settings. The overall performance of PV cells is affected by several factors, including solar irradiance, operating temperature, installation site parameters, prevailing weather, and shading effects. In the presented study, three distinct PV modules were analyzed using a sophisticated large-scale steady-state solar simulator. The current–voltage (I-V) characteristics of each module were precisely measured and subsequently scrutinized. To augment the analysis, a three-layer artificial neural network, specifically the multilayer perceptron (MLP), was developed. The experimental measurements, along with the outputs derived from the MLP model, served as the foundation for a comprehensive global sensitivity analysis (GSA). The experimental results revealed variances between the manufacturer’s declared values and those recorded during testing. The first module achieved a maximum power point that exceeded the manufacturer’s specification. Conversely, the second and third modules delivered power values corresponding to only 85–87% and 95–98% of their stated capacities, respectively. The global sensitivity analysis further indicated that while certain parameters, such as efficiency and the ratio of Voc/V, played a dominant role in influencing the power-voltage relationship, another parameter, U, exhibited a comparatively minor effect. These results highlight the significant potential of integrating machine learning techniques into the performance evaluation and predictive analysis of photovoltaic modules. Full article
(This article belongs to the Special Issue New Trends in Renewable Energy and Power Systems)
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14 pages, 2205 KiB  
Article
Optimizing Preclinical Skill Assessment for Handpiece-Naïve Students: A Strategic Approach
by Reinhard Chun Wang Chau, Szabolcs Felszeghy, Maria F. Sittoni-Pino, Santiago Arias-Herrera, Sompop Bencharit, Margrit Maggio, Murat Mutluay, David P. Rice, Walter Yu Hang Lam, Sıla Nur Usta, Barry F. Quinn, Jorge Tricio, Masako Nagasawa, Mihaela Pantea, Marina Imre, Ana Maria Cristina Tancu, Amitha Ranauta, Arzu Tezvergil-Mutluay, Satu Korpisaari, Kaisa Leinonen, Mikko Liukkonen, Outi S. Huhtela, Ulf T. Örtengren and Peter Lingströmadd Show full author list remove Hide full author list
Dent. J. 2025, 13(8), 363; https://doi.org/10.3390/dj13080363 - 11 Aug 2025
Viewed by 268
Abstract
Background: Preclinical dental training requires simulation-based tools to develop fine motor skills, but traditional models like plastic teeth often lack realistic tactile feedback, and systematic evaluations of multi-layered drilling plates are scarce. This study aimed to evaluate the educational utility and perceived [...] Read more.
Background: Preclinical dental training requires simulation-based tools to develop fine motor skills, but traditional models like plastic teeth often lack realistic tactile feedback, and systematic evaluations of multi-layered drilling plates are scarce. This study aimed to evaluate the educational utility and perceived realism of a novel multi-layered drilling plate designed to simulate enamel, dentin, and pulp, with null hypotheses that it would not differ in realism from natural dental tissues or in educational utility from existing tools. Methods: Seventy dental educators (mean preclinical teaching experience: 112.9 ± 116.7 months) from 14 institutions across four continents assessed the plates using standardized protocols. Statistical analysis (Mann–Whitney U Test) was performed to analyze the results. Results: Quantitative ratings (1–10 scale) showed high mean scores for drilling quality (enamel: 7.80 ± 1.55, dentin: 7.27 ± 1.94, pulp: 7.48 ± 2.33), surface smoothness (enamel: 8.17 ± 1.55, dentin: 8.17 ± 1.57), and ergonomic visibility (8.56 ± 1.58), with 90% passing grades, rejecting the null hypothesis of no difference in educational utility. Tissue transition scores (enamel/dentin: 7.09 ± 2.56; dentin/pulp: 6.86 ± 2.46) showed significant differences (p < 0.05) in realism from natural tissues, rejecting the null hypothesis of no difference. Inter-rater reliability was poor (Krippendorff’s alpha: 0.449 for failing scores, 0.211 for passing scores). Qualitative feedback praised ease of use but noted limitations in dentin haptic simulation. Conclusions: The drilling plate shows promise for skill development, though without controlled comparisons to existing tools, its relative efficacy remains preliminary. Further research on student outcomes and tool refinement is needed to validate its use in dental education. Full article
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34 pages, 3764 KiB  
Review
Research Progress and Applications of Artificial Intelligence in Agricultural Equipment
by Yong Zhu, Shida Zhang, Shengnan Tang and Qiang Gao
Agriculture 2025, 15(15), 1703; https://doi.org/10.3390/agriculture15151703 - 7 Aug 2025
Viewed by 468
Abstract
With the growth of the global population and the increasing scarcity of arable land, traditional agricultural production is confronted with multiple challenges, such as efficiency improvement, precision operation, and sustainable development. The progressive advancement of artificial intelligence (AI) technology has created a transformative [...] Read more.
With the growth of the global population and the increasing scarcity of arable land, traditional agricultural production is confronted with multiple challenges, such as efficiency improvement, precision operation, and sustainable development. The progressive advancement of artificial intelligence (AI) technology has created a transformative opportunity for the intelligent upgrade of agricultural equipment. This article systematically presents recent progress in computer vision, machine learning (ML), and intelligent sensing. The key innovations are highlighted in areas such as object detection and recognition (e.g., a K-nearest neighbor (KNN) achieved 98% accuracy in distinguishing vibration signals across operation stages); autonomous navigation and path planning (e.g., a deep reinforcement learning (DRL)-optimized task planner for multi-arm harvesting robots reduced execution time by 10.7%); state perception (e.g., a multilayer perceptron (MLP) yielded 96.9% accuracy in plug seedling health classification); and precision control (e.g., an intelligent multi-module coordinated control system achieved a transplanting efficiency of 5000 plants/h). The findings reveal a deep integration of AI models with multimodal perception technologies, significantly improving the operational efficiency, resource utilization, and environmental adaptability of agricultural equipment. This integration is catalyzing the transition toward intelligent, automated, and sustainable agricultural systems. Nevertheless, intelligent agricultural equipment still faces technical challenges regarding data sample acquisition, adaptation to complex field environments, and the coordination between algorithms and hardware. Looking ahead, the convergence of digital twin (DT) technology, edge computing, and big data-driven collaborative optimization is expected to become the core of next-generation intelligent agricultural systems. These technologies have the potential to overcome current limitations in perception and decision-making, ultimately enabling intelligent management and autonomous decision-making across the entire agricultural production chain. This article aims to provide a comprehensive foundation for advancing agricultural modernization and supporting green, sustainable development. Full article
(This article belongs to the Section Agricultural Technology)
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27 pages, 502 KiB  
Article
A Blockchain-Based Secure Data Transaction and Privacy Preservation Scheme in IoT System
by Jing Wu, Zeteng Bian, Hongmin Gao and Yuzhe Wang
Sensors 2025, 25(15), 4854; https://doi.org/10.3390/s25154854 - 7 Aug 2025
Viewed by 219
Abstract
With the explosive growth of Internet of Things (IoT) devices, massive amounts of heterogeneous data are continuously generated. However, IoT data transactions and sharing face multiple challenges such as limited device resources, untrustworthy network environment, highly sensitive user privacy, and serious data silos. [...] Read more.
With the explosive growth of Internet of Things (IoT) devices, massive amounts of heterogeneous data are continuously generated. However, IoT data transactions and sharing face multiple challenges such as limited device resources, untrustworthy network environment, highly sensitive user privacy, and serious data silos. How to achieve fine-grained access control and privacy protection for massive devices while ensuring secure and reliable data circulation has become a key issue that needs to be urgently addressed in the current IoT field. To address the above challenges, this paper proposes a blockchain-based data transaction and privacy protection framework. First, the framework builds a multi-layer security architecture that integrates blockchain and IPFS and adapts to the “end–edge–cloud” collaborative characteristics of IoT. Secondly, a data sharing mechanism that takes into account both access control and interest balance is designed. On the one hand, the mechanism uses attribute-based encryption (ABE) technology to achieve dynamic and fine-grained access control for massive heterogeneous IoT devices; on the other hand, it introduces a game theory-driven dynamic pricing model to effectively balance the interests of both data supply and demand. Finally, in response to the needs of confidential analysis of IoT data, a secure computing scheme based on CKKS fully homomorphic encryption is proposed, which supports efficient statistical analysis of encrypted sensor data without leaking privacy. Security analysis and experimental results show that this scheme is secure under standard cryptographic assumptions and can effectively resist common attacks in the IoT environment. Prototype system testing verifies the functional completeness and performance feasibility of the scheme, providing a complete and effective technical solution to address the challenges of data integrity, verifiable transactions, and fine-grained access control, while mitigating the reliance on a trusted central authority in IoT data sharing. Full article
(This article belongs to the Special Issue Blockchain-Based Solutions to Secure IoT)
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46 pages, 3093 KiB  
Review
Security and Privacy in the Internet of Everything (IoE): A Review on Blockchain, Edge Computing, AI, and Quantum-Resilient Solutions
by Haluk Eren, Özgür Karaduman and Muharrem Tuncay Gençoğlu
Appl. Sci. 2025, 15(15), 8704; https://doi.org/10.3390/app15158704 - 6 Aug 2025
Viewed by 747
Abstract
The IoE forms the foundation of the modern digital ecosystem by enabling seamless connectivity and data exchange among smart devices, sensors, and systems. However, the inherent nature of this structure, characterized by high heterogeneity, distribution, and resource constraints, renders traditional security approaches insufficient [...] Read more.
The IoE forms the foundation of the modern digital ecosystem by enabling seamless connectivity and data exchange among smart devices, sensors, and systems. However, the inherent nature of this structure, characterized by high heterogeneity, distribution, and resource constraints, renders traditional security approaches insufficient in areas such as data privacy, authentication, access control, and scalable protection. Moreover, centralized security systems face increasing fragility due to single points of failure, various AI-based attacks, including adversarial learning, model poisoning, and deepfakes, and the rising threat of quantum computers to encryption protocols. This study systematically examines the individual and integrated solution potentials of technologies such as Blockchain, Edge Computing, Artificial Intelligence, and Quantum-Resilient Cryptography within the scope of IoE security. Comparative analyses are provided based on metrics such as energy consumption, latency, computational load, and security level, while centralized and decentralized models are evaluated through a multi-layered security lens. In addition to the proposed multi-layered architecture, the study also structures solution methods and technology integrations specific to IoE environments. Classifications, architectural proposals, and the balance between performance and security are addressed from both theoretical and practical perspectives. Furthermore, a future vision is presented regarding federated learning-based privacy-preserving AI solutions, post-quantum digital signatures, and lightweight consensus algorithms. In this context, the study reveals existing vulnerabilities through an interdisciplinary approach and proposes a holistic framework for sustainable, scalable, and quantum-compatible IoE security. Full article
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23 pages, 2295 KiB  
Review
Advances in Interfacial Engineering and Structural Optimization for Diamond Schottky Barrier Diodes
by Shihao Lu, Xufang Zhang, Shichao Wang, Mingkun Li, Shuopei Jiao, Yuesong Liang, Wei Wang and Jing Zhang
Materials 2025, 18(15), 3657; https://doi.org/10.3390/ma18153657 - 4 Aug 2025
Viewed by 365
Abstract
Diamond, renowned for its exceptional electrical, physical, and chemical properties, including ultra-wide bandgap, superior hardness, high thermal conductivity, and unparalleled stability, serves as an ideal candidate for next-generation high-power and high-temperature electronic devices. Among diamond-based devices, Schottky barrier diodes (SBDs) have garnered significant [...] Read more.
Diamond, renowned for its exceptional electrical, physical, and chemical properties, including ultra-wide bandgap, superior hardness, high thermal conductivity, and unparalleled stability, serves as an ideal candidate for next-generation high-power and high-temperature electronic devices. Among diamond-based devices, Schottky barrier diodes (SBDs) have garnered significant attention due to their simple architecture and superior rectifying characteristics. This review systematically summarizes recent advances in diamond SBDs, focusing on both metal–semiconductor (MS) and metal–interlayer–semiconductor (MIS) configurations. For MS structures, we critically analyze the roles of single-layer metals (including noble metals, transition metals, and other metals) and multilayer metals in modulating Schottky barrier height (SBH) and enhancing thermal stability. However, the presence of interface-related issues such as high densities of surface states and Fermi level pinning often leads to poor control of the SBH, limiting device performance and reliability. To address these challenges and achieve high-quality metal/diamond interfaces, researchers have proposed various interface engineering strategies. In particular, the introduction of interfacial layers in MIS structures has emerged as a promising approach. For MIS architectures, functional interlayers—including high-k materials (Al2O3, HfO2, SnO2) and low-work-function materials (LaB6, CeB6)—are evaluated for their efficacy in interface passivation, barrier modulation, and electric field control. Terminal engineering strategies, such as field-plate designs and surface termination treatments, are also highlighted for their role in improving breakdown voltage. Furthermore, we emphasize the limitations in current parameter extraction from current–voltage (I–V) properties and call for a unified new method to accurately determine SBH. This comprehensive analysis provides critical insights into interface engineering strategies and evaluation protocols for high-performance diamond SBDs, paving the way for their reliable deployment in extreme conditions. Full article
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19 pages, 5098 KiB  
Article
Quantification of Suspended Sediment Concentration Using Laboratory Experimental Data and Machine Learning Model
by Sathvik Reddy Nookala, Jennifer G. Duan, Kun Qi, Jason Pacheco and Sen He
Water 2025, 17(15), 2301; https://doi.org/10.3390/w17152301 - 2 Aug 2025
Viewed by 483
Abstract
Monitoring sediment concentration in water bodies is crucial for assessing water quality, ecosystems, and environmental health. However, physical sampling and sensor-based approaches are labor-intensive and unsuitable for large-scale, continuous monitoring. This study employs machine learning models to estimate suspended sediment concentration using images [...] Read more.
Monitoring sediment concentration in water bodies is crucial for assessing water quality, ecosystems, and environmental health. However, physical sampling and sensor-based approaches are labor-intensive and unsuitable for large-scale, continuous monitoring. This study employs machine learning models to estimate suspended sediment concentration using images captured in natural light, named RGB, and near-infrared (NIR) conditions. A controlled dataset of approximately 1300 images with SSC values ranging from 1000 mg/L to 150,000 mg/L was developed, incorporating temperature, time of image capture, and solar irradiance as additional features. Random forest regression and gradient boosting regression were trained on mean RGB values, red reflectance, time of captured, and temperature for natural light images, achieving up to 72.96% accuracy within a 30% relative error. In contrast, NIR images leveraged gray-level co-occurrence matrix texture features and temperature, reaching 83.08% accuracy. Comparative analysis showed that ensemble models outperformed deep learning models like Convolutional Neural Networks and Multi-Layer Perceptrons, which struggled with high-dimensional feature extraction. These findings suggest that using machine learning models and RGB and NIR imagery offers a scalable, non-invasive, and cost-effective way of sediment monitoring in support of water quality assessment and environmental management. Full article
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18 pages, 1621 KiB  
Article
The Evaluation of Cellulose from Agricultural Waste as a Polymer for the Controlled Release of Ibuprofen Through the Formulation of Multilayer Tablets
by David Sango-Parco, Lizbeth Zamora-Mendoza, Yuliana Valdiviezo-Cuenca, Camilo Zamora-Ledezma, Si Amar Dahoumane, Floralba López and Frank Alexis
Bioengineering 2025, 12(8), 838; https://doi.org/10.3390/bioengineering12080838 - 1 Aug 2025
Viewed by 507
Abstract
This research demonstrates the potential of plant waste cellulose as a remarkable biomaterial for multilayer tablet formulation. Rice husks (RC) and orange peels (OC) were used as cellulose sources and characterized for a comparison with commercial cellulose. The FTIR characterization shows minimal differences [...] Read more.
This research demonstrates the potential of plant waste cellulose as a remarkable biomaterial for multilayer tablet formulation. Rice husks (RC) and orange peels (OC) were used as cellulose sources and characterized for a comparison with commercial cellulose. The FTIR characterization shows minimal differences in their chemical components, making them equivalent for compression into tablets containing ibuprofen. TGA measurements indicate that the RC is slightly better for multilayer formulations due to its favorable degradation profile. This is corroborated by an XRD analysis that reveals its higher crystalline fraction (~55%). The use of a heat press at combined high pressures and temperatures allows the layer-by-layer tablet formulation of ibuprofen, taken as a model drug. Additionally, this study compares the release profile of three types of tablets compressed with cellulose: mixed (MIX), two-layer (BL), and three-layer (TL). The MIX tablet shows a profile like that of conventional ibuprofen tablets. Although both BL and TL tablets significantly reduce their release percentage in the first hours, the TL ones have proven to be better in the long run. In fact, formulations made of extracted cellulose sandwiching ibuprofen display a zero-order release profile and prolonged release since the drug release amounts to ~70% after 120 h. This makes the TL formulations ideal for maintaining the therapeutic effect of the drug and improving patients’ wellbeing and compliance while reducing adverse effects. Full article
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24 pages, 3553 KiB  
Article
A Hybrid Artificial Intelligence Framework for Melanoma Diagnosis Using Histopathological Images
by Alberto Nogales, María C. Garrido, Alfredo Guitian, Jose-Luis Rodriguez-Peralto, Carlos Prados Villanueva, Delia Díaz-Prieto and Álvaro J. García-Tejedor
Technologies 2025, 13(8), 330; https://doi.org/10.3390/technologies13080330 - 1 Aug 2025
Viewed by 335
Abstract
Cancer remains one of the most significant global health challenges due to its high mortality rates and the limited understanding of its progression. Early diagnosis is critical to improving patient outcomes, especially in skin cancer, where timely detection can significantly enhance recovery rates. [...] Read more.
Cancer remains one of the most significant global health challenges due to its high mortality rates and the limited understanding of its progression. Early diagnosis is critical to improving patient outcomes, especially in skin cancer, where timely detection can significantly enhance recovery rates. Histopathological analysis is a widely used diagnostic method, but it is a time-consuming process that heavily depends on the expertise of highly trained specialists. Recent advances in Artificial Intelligence have shown promising results in image classification, highlighting its potential as a supportive tool for medical diagnosis. In this study, we explore the application of hybrid Artificial Intelligence models for melanoma diagnosis using histopathological images. The dataset used consisted of 506 histopathological images, from which 313 curated images were selected after quality control and preprocessing. We propose a two-step framework that employs an Autoencoder for dimensionality reduction and feature extraction of the images, followed by a classification algorithm to distinguish between melanoma and nevus, trained on the extracted feature vectors from the bottleneck of the Autoencoder. We evaluated Support Vector Machines, Random Forest, Multilayer Perceptron, and K-Nearest Neighbours as classifiers. Among these, the combinations of Autoencoder with K-Nearest Neighbours achieved the best performance and inference time, reaching an average accuracy of approximately 97.95% on the test set and requiring 3.44 min per diagnosis. The baseline comparison results were consistent, demonstrating strong generalisation and outperforming the other models by 2 to 13 percentage points. Full article
(This article belongs to the Special Issue Application of Artificial Intelligence in Medical Image Analysis)
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12 pages, 3890 KiB  
Article
Visualization of Film Formation Process of Copolyesteramide Containing Phthalazine Moieties During Interfacial Polymerization
by Zeyuan Liu, Hailong Li, Qian Liu, Zhaoqi Wang, Danhui Wang, Peiqi Xu, Xigao Jian and Shouhai Zhang
Membranes 2025, 15(8), 233; https://doi.org/10.3390/membranes15080233 - 1 Aug 2025
Viewed by 299
Abstract
Interfacial polymerization (IP) has been widely utilized to synthesize composite membranes. However, precise control of this reaction remains a challenge due to the complexity of the IP process. Herein, an optical three-dimensional microscope was used to directly observe the IP process. To construct [...] Read more.
Interfacial polymerization (IP) has been widely utilized to synthesize composite membranes. However, precise control of this reaction remains a challenge due to the complexity of the IP process. Herein, an optical three-dimensional microscope was used to directly observe the IP process. To construct copolyesteramide containing phthalazine moiety films, rigid monomer 4-(4′-hydroxyphenyl)-2,3-phthalazin-1-one (DHPZ) and flexible monomer piperazine (PIP) were used as aqueous phase monomers, and trimesoyl chloride (TMC) served as the organic phase monomer. Multilayer cellular structures were observed for the copolyesteramide films during the IP process. The effects of multiple factors including the ratio between flexible and rigid monomers, co-solvents, and the addition of phase transfer catalysts on the film growth and the morphologies were investigated. This research aims to deepen our understanding of the IP process, especially for the principles which govern polymer film growth and morphology, to promote new methodologies for regulating interfacial polymerization in composite membrane preparation. Full article
(This article belongs to the Section Membrane Fabrication and Characterization)
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20 pages, 3810 KiB  
Article
Exploring Drought Response: Machine-Learning-Based Classification of Rice Tolerance Using Root and Physiological Traits
by Wuttichai Gunnula, Nantawan Kanawapee, Hathairat Chokthaweepanich and Piyaporn Phansak
Agronomy 2025, 15(8), 1840; https://doi.org/10.3390/agronomy15081840 - 29 Jul 2025
Viewed by 461
Abstract
Drought is a key limitation for rice productivity. While oxidative stress markers like hydrogen peroxide (H2O2) are important for drought adaptation, the predictive value of combining root anatomical and physiological traits is underexplored. We assessed 20 rice cultivars under [...] Read more.
Drought is a key limitation for rice productivity. While oxidative stress markers like hydrogen peroxide (H2O2) are important for drought adaptation, the predictive value of combining root anatomical and physiological traits is underexplored. We assessed 20 rice cultivars under drought and control conditions using a random forest, a multi-layer perceptron, and a SHAP-optimized stacking ensemble. The stacking ensemble achieved the highest classification accuracy (81.8%) and identified hydrogen peroxide, relative water content, and endodermis inner circumference as key predictors. SHAP analysis revealed important interactions between root anatomical and physiological traits, providing new biological insights into drought tolerance. Our integrative approach, supported by robust cross-validation, improves predictive power and transparency for breeding drought-resilient rice cultivars. Full article
(This article belongs to the Section Precision and Digital Agriculture)
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