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Search Results (5,505)

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22 pages, 757 KB  
Article
The Impact of ENSO Shocks on Firm Performance: The Role of Supply Chain Resilience and Network Complexity in Energy Firms
by Xueting Luo, Ke Gong, Aixing Li, Xiaomei Ding and Yuhang Yang
Sustainability 2026, 18(7), 3261; https://doi.org/10.3390/su18073261 (registering DOI) - 26 Mar 2026
Abstract
Escalating climate volatility, particularly the El Niño/Southern Oscillation (ENSO), poses severe operational and financial risks to corporate sustainability in the energy sector. However, quantitative evidence regarding how macro-level climate shocks transmit to micro-level operational performance remains scarce. Integrating dynamic capability and social network [...] Read more.
Escalating climate volatility, particularly the El Niño/Southern Oscillation (ENSO), poses severe operational and financial risks to corporate sustainability in the energy sector. However, quantitative evidence regarding how macro-level climate shocks transmit to micro-level operational performance remains scarce. Integrating dynamic capability and social network theories, this study analyzes a panel of 103 Chinese listed energy firms (2005–2022) using System GMM, mediation, and moderation models. The results indicate that ENSO intensity significantly impairs performance; specifically, a 1 °C rise in sea surface temperature anomalies decreases firms’ return on assets (ROAs) by 0.142%. We identify supply chain resilience as a critical strategic mechanism for climate adaptation, where response capacity acts as the dominant mediating channel, while recovery capacity functions as an independent compensatory mechanism. Conversely, supply network complexity—across horizontal, vertical, and spatial dimensions—amplifies the negative impact of climate disruptions by hindering resource mobility. Heterogeneity analysis reveals that state-owned enterprises exhibit stronger institutional resilience, and firms in southern regions partially offset impacts through hydropower advantages. This study bridges climate science with operations management, offering strategic guidance for managers to configure resilient, sustainable supply chains capable of withstanding environmental turbulence. Full article
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21 pages, 1441 KB  
Article
The Infrastructuralization of Water: Water Management and Sustainable Development of Kinmen Island
by Yan Zhou and Yong Zhou
Water 2026, 18(7), 791; https://doi.org/10.3390/w18070791 (registering DOI) - 26 Mar 2026
Abstract
Islands often suffer from relatively limited freshwater resources, and the effective utilization and distribution of water resources are a key issues for the sustainable development of island-based economies and societies. While island water security has been widely discussed, few studies trace the socio-technical [...] Read more.
Islands often suffer from relatively limited freshwater resources, and the effective utilization and distribution of water resources are a key issues for the sustainable development of island-based economies and societies. While island water security has been widely discussed, few studies trace the socio-technical construction of island water-supply systems across the stages of planning, construction, and operation. Integrating Actor-Network Theory with political ecology, this study investigates the water-supply infrastructure of Kinmen. Drawing on official archives, participant observation, and in-depth interviews, this research analyzes the collective actions mobilized to address Kinmen’s water scarcity following the lifting of martial law in 1992. These efforts jointly reshaped both water-supply practices and the infrastructural network. Over the past three decades, Kinmen’s water-supply system has transformed into a sophisticated technological network, integrating reservoirs, desalination plants, and advanced sewage infrastructure. The introduction of these technologies, which function as critical non-human actors within the system, marks a clear shift in how water is managed and distributed. However, the rapid expansion of water-intensive industries, especially tourism, liquor distilling, and cattle farming, has outpaced local ecological limits, precipitating the current water crisis. The study concludes that this shortage has been mitigated through the strategic integration of water sources, most notably the cross-strait pipeline from mainland China, which now provides more than 80 percent of the island’s water. This transition marks a profound shift in the island’s socio-technical and geopolitical network. Full article
23 pages, 1311 KB  
Article
An AI-Powered Integrated Management Model for a Sustainable Electric Vehicle Charging Infrastructure
by Arianna D’Ulizia, Alessia D’Andrea, Marco Pirrone and Daizhong Su
Sustainability 2026, 18(7), 3257; https://doi.org/10.3390/su18073257 (registering DOI) - 26 Mar 2026
Abstract
The rapid increase of electric mobility is challenging the deployment design and operation of electric vehicle charging infrastructure in a scalable, sustainable, operationally reliable, and regulation-compliant manner. Although advances in both digitization and artificial intelligence in recent years have made smarter charging solutions [...] Read more.
The rapid increase of electric mobility is challenging the deployment design and operation of electric vehicle charging infrastructure in a scalable, sustainable, operationally reliable, and regulation-compliant manner. Although advances in both digitization and artificial intelligence in recent years have made smarter charging solutions possible, today’s approaches tend to concentrate on individual technical parts without considering holistic views. This paper introduces an AI-driven integrated management model for sustainable EV charging infrastructures, composed of four interconnected layers, namely, Eco-Design, Digital Tools, Risk Management, and Governance. In particular, each layer focuses on specific aspects of functionality, including environmentally friendly design decisions, digital monitoring capabilities, proactive risk reduction, and strategic coordination. Compared with existing approaches that address isolated technical or operational aspects, the proposed model provides an integrated, multi-layer architecture that unifies eco-design, digital intelligence, risk management and governance, offering a more holistic and scalable foundation for sustainable EV charging infrastructures. It represents the conceptual output of a structured integration of existing technologies, design principles and governance needs. Considering that fragmented, solution-specific advances are reduced by including interdependencies between layers, the model allows us to better integrate technical operations, resilience mechanisms and sustainability goals. The model is theoretical and offers a scalable point of reference for researchers, as well as infrastructure operators and politicians. Full article
(This article belongs to the Special Issue The Role of AI in Sustainable Development and Risk Management)
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37 pages, 3866 KB  
Review
Open Surgical Management of Renal Cell Carcinoma with Infradiaphragmatic Venous Tumor Thrombus (Mayo Levels 0–III): The Epitome of Surgical Self-Reliance in Urology
by Dorin Novacescu, Adelina Baloi, Silviu Latcu, Flavia Zara, Dorel Sandesc, Cristina-Stefania Dumitru, Cristian Condoiu, Razvan Bardan, Vlad Dema, Radu Caprariu, Talida Georgiana Cut and Alin Cumpanas
Cancers 2026, 18(7), 1080; https://doi.org/10.3390/cancers18071080 - 26 Mar 2026
Abstract
Background/Objectives: Renal cell carcinoma (RCC) with venous tumor thrombus (VTT) extending into the inferior vena cava (IVC) occurs in 4–10% of patients and represents one of the most technically demanding scenarios in urologic surgery. Open radical nephrectomy with en bloc thrombectomy remains [...] Read more.
Background/Objectives: Renal cell carcinoma (RCC) with venous tumor thrombus (VTT) extending into the inferior vena cava (IVC) occurs in 4–10% of patients and represents one of the most technically demanding scenarios in urologic surgery. Open radical nephrectomy with en bloc thrombectomy remains the gold standard for infradiaphragmatic disease (Mayo Levels 0–III), offering the only realistic prospect for long-term cure. This narrative review provides a technically oriented, evidence-based guide for surgical urologists managing these complex cases. Methods: PubMed/MEDLINE, Scopus, and Web of Science were searched (1970–March 2025) using terms related to RCC, venous tumor thrombus, IVC thrombectomy, and perioperative management. Priority was given to prospective studies, systematic reviews, large retrospective cohorts, and current guidelines (EAU 2025, NCCN v2.2024). Original intraoperative photographs supplement procedural descriptions. Results: We detail the complete perioperative pathway: VTT classification (Mayo/AJCC), multimodal imaging, patient optimization, and level-specific open surgical techniques—ranging from Satinsky clamping for Level 0–I thrombi to full piggyback liver mobilization with hepatic vascular exclusion for Level III disease. Contemporary perioperative mortality is <2% at high-volume centers (reported in single and multicenter retrospective series from high-volume institutions), with 5-year cancer-specific survival of approximately 50–60% in non-metastatic cases. Adjuvant pembrolizumab is now a standard of care following the KEYNOTE-564 trial. Neoadjuvant immune checkpoint inhibitor plus tyrosine kinase inhibitor combinations show promising VTT downstaging rates (44–100%), though their role remains investigational. Robotic-assisted thrombectomy demonstrates favorable perioperative outcomes for Level I–II thrombi at experienced centers. Conclusions: Open surgery remains the cornerstone of curative treatment for RCC with infradiaphragmatic VTT, requiring meticulous preoperative planning and multidisciplinary collaboration at high-volume centers. Integration of perioperative systemic therapies and robotic-assisted approaches holds promise for further improving outcomes in this challenging patient population. Full article
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28 pages, 12137 KB  
Article
A Customized Business Intelligence Dashboard Utilizing Building Information Modeling for Better Control and Management of Construction Projects
by Hamzah Abdulaziz and Hani M. Ahmed
Buildings 2026, 16(7), 1318; https://doi.org/10.3390/buildings16071318 - 26 Mar 2026
Abstract
The construction sector is one of the primary areas that underpin a country’s economic development. However, this sector is characterized by various types of obstacles, including the participation of numerous stakeholders, strict schedules, limited resources, and the management of vast amounts of data [...] Read more.
The construction sector is one of the primary areas that underpin a country’s economic development. However, this sector is characterized by various types of obstacles, including the participation of numerous stakeholders, strict schedules, limited resources, and the management of vast amounts of data throughout the project lifecycle. Building Information Modeling (BIM) has emerged as a promising technology for centralizing and managing construction data throughout the project lifecycle. However, having the ability to extract real-time, decision-oriented insights from BIM models remains a challenge for project stakeholders. To address this limitation, this research paper explores the integration of BIM with Business Intelligence (BI) to enhance control and management of construction projects throughout the development of a customized Power BI dashboard. The proposed framework of the paper utilizes BIM’s data-rich environment and Power BI’s advanced analytical and visualization capabilities to deliver real-time and interactive insights about project performance and progress. The customized dashboard enables stakeholders, especially project managers, to monitor key performance indicators of the project that are related to cost and schedule. It also supports progress tracking, early identification of inefficiencies, and data-driven decision-making. To demonstrate the practical application of the proposed framework, a case study was conducted. The results indicate that integrating BIM with BI helps in enhancing project control, improving transparency, and facilitating collaboration between stakeholders through a centralized cloud platform that can be easily accessed through desktop and mobile devices. Full article
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26 pages, 962 KB  
Review
Integrating Technology into Urticaria Management: Telemedicine, Remote Monitoring and Patient-Centered Care
by Ester Topa, Mattia Cristallo, Angela Rizzi, Donatella Lamacchia, Sara Gamberale, Cristiano Caruso, Oliviero Rossi, Elisabetta Di Leo, Maria Bova and Eustachio Nettis
Biomedicines 2026, 14(4), 753; https://doi.org/10.3390/biomedicines14040753 - 26 Mar 2026
Abstract
Background: Urticaria, particularly chronic urticaria (CU), is a highly prevalent inflammatory skin disorder characterized by recurrent wheals and/or angioedema with a fluctuating and unpredictable course that significantly impairs quality of life and requires long-term monitoring. Despite established therapeutic guidelines, disease control remains [...] Read more.
Background: Urticaria, particularly chronic urticaria (CU), is a highly prevalent inflammatory skin disorder characterized by recurrent wheals and/or angioedema with a fluctuating and unpredictable course that significantly impairs quality of life and requires long-term monitoring. Despite established therapeutic guidelines, disease control remains suboptimal in a considerable proportion of patients. Telemedicine has emerged as a promising adjunctive strategy for chronic disease management. This review aims to critically evaluate the role, applications, benefits, and limitations of telemedicine and digital health interventions in urticaria management. Methods: A scoping review of the literature was conducted focusing on studies addressing telemedicine, digital patient-reported outcomes, mobile health applications, and remote monitoring strategies in urticaria. Evidence from pandemic and post-pandemic telemedicine models was also analyzed to identify transferable approaches. Results: Telemedicine demonstrates significant potential in urticaria management by enabling structured symptom monitoring, facilitating remote follow-up during therapeutic escalation (including biologic therapies), improving patient empowerment and adherence, and reducing healthcare utilization and indirect costs. Digital tools such as electronic diaries and validated PRO-based applications support continuous disease assessment. However, telemedicine cannot replace direct clinical examination, and limitations include diagnostic uncertainty, digital inequalities, data privacy concerns, and lack of large disease specific trials. Conclusions: Telemedicine represents a valuable complementary and integrative model for urticaria care, particularly suited for chronic disease monitoring. Hybrid care pathways combining remote and in-person management appear to be the most effective and sustainable strategy. Further high-quality urticaria-specific studies and standardized digital frameworks are required to optimize its clinical implementation. Full article
(This article belongs to the Special Issue Urticaria: New Insights into Pathogenesis, Diagnosis and Therapy)
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32 pages, 16696 KB  
Article
An Intelligent Framework for Crowdsource-Based Spectrum Misuse Detection in Shared-Spectrum Networks
by Debarun Das and Taieb Znati
Network 2026, 6(2), 19; https://doi.org/10.3390/network6020019 - 26 Mar 2026
Abstract
Dynamic Spectrum Access (DSA) has emerged as a viable solution to address spectrum scarcity in shared-spectrum networks. In response, the FCC established the Citizens Broadband Radio Service (CBRS) to manage and facilitate shared use of the federal and non-federal spectrum in a three-tiered [...] Read more.
Dynamic Spectrum Access (DSA) has emerged as a viable solution to address spectrum scarcity in shared-spectrum networks. In response, the FCC established the Citizens Broadband Radio Service (CBRS) to manage and facilitate shared use of the federal and non-federal spectrum in a three-tiered access and authorization framework. However, due to the open nature of spectrum access and the usually limited coverage of the monitoring infrastructure, enforcing access rights in a shared-spectrum network becomes a daunting challenge. In this paper, we stipulate the use of crowdsourcing as a viable approach to engaging volunteers in spectrum monitoring in order to enforce spectrum access rights robustly and reliably. The success of this approach, however, hinges strongly on ensuring that spectrum access enforcement is carried out by reliable and trustworthy volunteers within the monitored area. To this end, a hybrid spectrum monitoring framework is proposed, which relies on opportunistically recruiting volunteers to augment the otherwise limited infrastructure of trusted devices. Although a volunteer’s participation has the potential to enhance monitoring significantly, their mobility may become problematic in ensuring reliable coverage of the monitored spectrum area. To ensure continued monitoring, inspite of volunteer mobility, deep learning-based models are used to predict the likelihood that a volunteer will be available within the monitoring area. Three models, namely LSTM, GRU, and Transformer, are explored to assess their feasibility and viability to predict a volunteer’s availability likelihood over an extended time interval, in a given spectrum monitoring area. Recurrent Neural Networks (RNNs) such as GRU and LSTM are effective for tasks involving sequential data, where both spatial and temporal patterns matter, which is the focus of volunteer availability prediction in spectrum monitoring. Transformers, on the other hand, excel at handling long range dependencies and contextual understanding. Furthermore, their parallel processing capabilities allows faster training and inference compared to RNN-based models like GRU and LSTM. A simulation-based study is developed to assess the performance of these models, and carry out a comparative analysis of their ability to predict volunteers’ availability to monitor the spectrum reliably. To this end, a real-world trace dataset of volunteers’ location, collected over five years, is used. The simulation results show that the three models achieve high prediction accuracy of volunteers’ availability, ranging from 0.82 to 0.92. The results also show that a GRU-based model outperforms LSTM and Transformer-based models, in terms of accuracy, Root Mean Square Error (RMSE), geodesic distance, and execution time. Full article
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19 pages, 4824 KB  
Article
Understanding Regional and Stylistic Diversity in Chinese Rural Paper-Cutting Through Convolutional Neural Network-Based Image Classification
by Xiaochu Wu, Xiaoyue Yin, Xiaofeng Chen, Xudong You, Fang Zhang and Yi Xiao
Appl. Sci. 2026, 16(7), 3174; https://doi.org/10.3390/app16073174 - 25 Mar 2026
Abstract
As an important component of Chinese folk art, rural paper-cutting embodies rich regional cultural connotations and distinctive aesthetic expressions. In this study, a Chinese rural paper-cutting image dataset covering multiple regions and artistic styles was constructed, and a convolutional neural network (CNN)-based framework [...] Read more.
As an important component of Chinese folk art, rural paper-cutting embodies rich regional cultural connotations and distinctive aesthetic expressions. In this study, a Chinese rural paper-cutting image dataset covering multiple regions and artistic styles was constructed, and a convolutional neural network (CNN)-based framework was proposed for regional and stylistic identification of paper-cutting works. Five representative mainstream CNN models were evaluated for both tasks. For regional classification, all models achieved high accuracy, with EfficientNet-B1 attaining the highest accuracy of 91.46%. The style classification task was more challenging due to subtle visual differences, with MobileNetV3-Small achieving the highest accuracy of 73.20%. In addition, t-distributed stochastic neighbor embedding (t-SNE) visualizations further confirmed that the models were able to effectively distinguish different regional and stylistic categories in high-dimensional space. To enhance model interpretability, Gradient-weighted Class Activation Mapping (Grad-CAM) was applied to visualize the optimal models. The results show that the CNNs consistently focus on core structural features of paper-cutting works, suggesting that CNNs can capture visually and culturally meaningful features. Overall, this study demonstrates the feasibility of applying CNNs to the analysis of traditional folk art and provides a practical technical pathway for digital management, intelligent classification, and educational dissemination of rural paper-cutting art. Full article
(This article belongs to the Section Computing and Artificial Intelligence)
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18 pages, 1111 KB  
Article
A Dynamic Operational Framework Integrating Life Cycle Assessment and Ride-Level Emission Modelling for Shared E-Scooter Systems
by Yelda Karatepe Mumcu and Eray Erkal
Sustainability 2026, 18(7), 3202; https://doi.org/10.3390/su18073202 - 25 Mar 2026
Abstract
Shared e-scooter systems are frequently characterized as zero-emission mobility solutions; however, lifecycle greenhouse gas (GHG) emissions depend on manufacturing, electricity generation, and operational logistics. While conventional life cycle assessment (LCA) studies quantify environmental impacts using static average parameters, they rarely integrate lifecycle emissions [...] Read more.
Shared e-scooter systems are frequently characterized as zero-emission mobility solutions; however, lifecycle greenhouse gas (GHG) emissions depend on manufacturing, electricity generation, and operational logistics. While conventional life cycle assessment (LCA) studies quantify environmental impacts using static average parameters, they rarely integrate lifecycle emissions into real-time fleet decision-making. This study proposes a formally defined carbon-aware operational framework that integrates ride-level telemetry, time-varying electricity grid carbon intensity, amortized production emissions, and dynamically allocated logistics impacts into a unified optimization architecture. Lifecycle emissions are computed at ride-level granularity and incorporated into charging and rebalancing decisions through a constrained optimization framework. A multi-objective extension is introduced to account for environmental–economic trade-offs. An illustrative simulation of 1000 rides was conducted to evaluate the operational performance of the framework. Under the assumed baseline scenario, the illustrative carbon-aware simulation indicated a potential reduction of up to 24.5% relative to conventional scheduling. Sensitivity analysis across variations in grid carbon intensity, scooter lifetime, energy consumption, and logistics emissions demonstrated reduction outcomes ranging between 18% and 29%, indicating robustness to parameter uncertainty. The study does not present large-scale empirical validation but provides a mathematically formalized decision-support architecture that operationalizes lifecycle assessment within shared micro-mobility fleet management. The results suggest that integrating carbon metrics into operational control may substantially enhance the environmental performance of shared e-scooter systems. Future research should validate the framework using real-world fleet data and incorporate a comprehensive economic assessment. The proposed framework provides a scalable methodological basis for integrating environmental metrics into real-time micro-mobility management and urban sustainability planning. Full article
(This article belongs to the Section Sustainable Transportation)
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24 pages, 4011 KB  
Article
Comparative Evaluation of Traffic Load Prediction Models for Intelligent Transportation Systems Using High-Resolution Urban Data
by Sara Atef
Smart Cities 2026, 9(4), 56; https://doi.org/10.3390/smartcities9040056 - 25 Mar 2026
Abstract
Short-term traffic load prediction is a fundamental component of intelligent transportation systems (ITSs), supporting real-time monitoring, congestion mitigation, and adaptive traffic management in smart cities. Owing to the dynamic and nonlinear nature of urban traffic, identifying prediction models that align with real-world traffic [...] Read more.
Short-term traffic load prediction is a fundamental component of intelligent transportation systems (ITSs), supporting real-time monitoring, congestion mitigation, and adaptive traffic management in smart cities. Owing to the dynamic and nonlinear nature of urban traffic, identifying prediction models that align with real-world traffic dynamics remains a key challenge. This study presents a comparative evaluation of data-driven traffic load prediction models using high-resolution one-minute traffic data collected from a major urban roundabout in Jeddah, Saudi Arabia. The evaluated models include regression-based machine learning approaches and recurrent deep learning architectures, which are assessed under consistent preprocessing and evaluation conditions. Model performance is evaluated using standard error metrics and complemented by temporal and residual analyses to examine prediction behavior under different traffic regimes. The optimized GRU model achieved the best predictive accuracy with an RMSE of 149.12 veh/h, followed closely by the optimized LSTM model (RMSE = 150.85 veh/h). The results indicate that while conventional machine learning models can effectively capture overall traffic trends under relatively stable conditions, recurrent deep learning models demonstrate stronger capability in modeling nonlinear temporal dependencies and rapid traffic fluctuations when properly configured. In addition, a variability-based regime analysis was conducted to evaluate model robustness under different traffic demand dynamics, revealing that model performance advantages are context-dependent rather than universal. The findings highlight the importance of systematic comparative evaluation and data-driven model selection for developing reliable traffic prediction components in real-time ITS applications and sustainable urban mobility planning. Full article
(This article belongs to the Section Smart Urban Mobility, Transport, and Logistics)
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15 pages, 721 KB  
Article
Genetic Characterization of Carbapenem-Resistant Acinetobacter spp. Isolated from Diseased Companion Animals in Japan
by Saki Harada, Mari Matsuda, Yuta Hosoi, Taimu Toyama, Michiko Kawanishi and Hideto Sekiguchi
Antibiotics 2026, 15(4), 329; https://doi.org/10.3390/antibiotics15040329 - 24 Mar 2026
Abstract
Background/Objectives: Carbapenem-resistant Acinetobacter spp. represent an emerging concern in human medicine; however, their epidemiology and genetic backgrounds in companion animals in Japan remain unclear. This study aimed to determine the prevalence of carbapenem resistance among Acinetobacter spp. isolated from diseased dogs and cats [...] Read more.
Background/Objectives: Carbapenem-resistant Acinetobacter spp. represent an emerging concern in human medicine; however, their epidemiology and genetic backgrounds in companion animals in Japan remain unclear. This study aimed to determine the prevalence of carbapenem resistance among Acinetobacter spp. isolated from diseased dogs and cats and elucidate the underlying genetic mechanisms. Methods: In this surveillance study conducted as part of the Japanese Veterinary Antimicrobial Resistance Monitoring (JVARM) program, 139 isolates were collected from diseased companion animals across Japan (84 from dogs and 55 from cats) during 2020, 2021 and 2023. Antimicrobial susceptibility testing was performed for seven antimicrobials and carbapenem-resistant isolates (meropenem MIC ≥ 8 μg/mL) underwent whole-genome sequencing to identify resistance genes, genomic contexts, and associated mobile genetic elements. Results: Resistance rates to all tested antimicrobials were below 20%. Meropenem resistance was detected in three isolates: one from a dog and two from cats. These resistant strains were identified as A. radioresistens, A. proteolyticus, and A. johnsonii, all harboring carbapenemase genes. The A. radioresistens isolate carried chromosomal blaOXA-23, the A. proteolyticus isolate carried blaOXA-58, and the A. johnsonii isolate possessed a plasmid containing blaNDM-1 and blaOXA-58. This represents the first report of blaNDM-1-harboring Acinetobacter isolate from companion animals in Japan. Conclusions: Carbapenem-resistant Acinetobacter spp. remain rare in companion animals in Japan; however, insertion sequence mobility may promote resistance gene dissemination. As carbapenems are not approved for veterinary use in Japan, strict antimicrobial stewardship and appropriate hygiene management are essential. Full article
(This article belongs to the Special Issue Antibiotic Resistance in Bacterial Isolates of Animal Origin)
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13 pages, 1473 KB  
Article
Enhancing Ophthalmologists’ Accuracy in Detecting Convergence Insufficiency Using AI-Derived Graphical Outputs
by Ahmad Khatib, Haneen Jabaly-Habib, Shmuel Raz and Ilan Shimshoni
J. Clin. Transl. Ophthalmol. 2026, 4(2), 9; https://doi.org/10.3390/jcto4020009 - 24 Mar 2026
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Abstract
Background: Accurate evaluation of the Near Point of Convergence (NPC) is essential for diagnosing and managing convergence insufficiency (CI). Conventional assessment relies on the patient’s verbal feedback and the examiner’s visual observation, making it subjective and examiner-dependent. The AI-based MobileS platform, previously validated [...] Read more.
Background: Accurate evaluation of the Near Point of Convergence (NPC) is essential for diagnosing and managing convergence insufficiency (CI). Conventional assessment relies on the patient’s verbal feedback and the examiner’s visual observation, making it subjective and examiner-dependent. The AI-based MobileS platform, previously validated for both diagnosis and home-based therapy of CI, enables smartphone-based measurement and visualisation of NPC through eye tracking, without the need for verbal responses or additional equipment. This study, the third stage of our research programme, examined how ophthalmologists interpret NPC data when presented as videos versus AI-derived graphs. Methods: Twenty-two ophthalmologists completed an online questionnaire with 20 NPC test cases from the validated MobileS database, presented as both silent videos and AI-derived graphs. Accuracy was analysed using mixed-effects logistic regression, and continuous error was assessed using clustered bootstrap. Results: Graph-based interpretation showed higher odds of accurate NPC identification than video-based interpretation at the primary ±5 mm threshold (OR = 19.7, 95% CI: 13.50–28.74; p < 0.0001). Absolute error was lower for graphs than videos (Graphs − Videos: −22.73 mm; 95% CI: −26.88 to −18.59; p < 0.0001). “Uncertain” responses occurred in 28.2% of video-based assessments and 0% of graph-based assessments. Off-target errors decreased from 50.2% (videos) to 3.6% (graphs). Conclusions: AI-derived graphs of eye-movement data were associated with improved NPC estimation, suggesting a potential role in supporting clinical and tele-ophthalmology workflows. Full article
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20 pages, 1238 KB  
Article
Perceived Usability as a Factor Associated with Clinical Outcomes in Mobile Health Diabetes Management: A Bayesian Mediation and Equity Analysis
by Oscar Eduardo Rodríguez Montes, María del Carmen Gogeascoechea-Trejo and Clara Bermúdez-Tamayo
J. Clin. Med. 2026, 15(6), 2465; https://doi.org/10.3390/jcm15062465 - 23 Mar 2026
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Abstract
Background: While mobile health (mHealth) interventions show promise for type 2 diabetes management, mechanisms linking user experience to clinical outcomes remain poorly understood. We hypothesized that perceived usability may mediate associations between patient characteristics and short-term clinical changes, with implications for health equity [...] Read more.
Background: While mobile health (mHealth) interventions show promise for type 2 diabetes management, mechanisms linking user experience to clinical outcomes remain poorly understood. We hypothesized that perceived usability may mediate associations between patient characteristics and short-term clinical changes, with implications for health equity in digital interventions. Methods: Secondary analysis of the intervention arm from a randomized controlled trial in urban Mexican primary care (ClinicalTrials.gov NCT05924516). Participants used a diabetes self-management mobile application for 90 days. We assessed usability with the validated Computer System Usability Questionnaire (CSUQ; 16 items, 7-point scale) and measured clinical changes in body mass index (BMI), systolic blood pressure (SBP), and HbA1c. Bayesian mediation analysis (literature-informed priors) examined interface quality as a mediator of age-related clinical effects. Item-level analysis identified educational disparities in specific usability dimensions using independent t-tests adjusted for multiple comparisons. Results: Mean overall usability was 5.20/7 (SD = 0.89, 74th percentile). Interface quality mediated 39% of the age–SBP association. Participants experiencing high usability (≥6) versus low usability showed BMI reduction −0.78 vs. −0.21 kg/m2 (Cohen’s d = 0.56) and SBP reduction −7.3 vs. −1.2 mmHg (Cohen’s d = 0.51). No mediation effect was observed for HbA1c change. Users with ≤primary education (41% of sample) scored 1.9 points lower on error messages (3.2 vs. 5.1, p < 0.01) and 1.4 points lower on help documentation (3.6 vs. 5.0, p < 0.03). These disparities persisted after controlling for age and baseline severity. Conclusions: Perceived usability was associated with a potential mechanistic pathway linking user experience to clinical outcomes. Higher usability scores were associated with clinically meaningful improvements in cardiometabolic parameters. Educational disparities in understanding error messages and helping documentation represent modifiable design barriers. Implementing contextual error explanations with visual examples and plain-language help content may enhance both clinical effectiveness and equity in digital diabetes interventions. Full article
(This article belongs to the Special Issue Clinical Management for Metabolic Syndrome and Obesity)
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17 pages, 1493 KB  
Article
Slope-Controlled Partitioning of Vertical and Lateral Solute Transport Pathways Revealed by Inclined Leaching Experiments
by Xiaoli Zhou, Jiakun Dong, Buxu Sun, Ziyi Yang, Xiaoping Sun and Yu Shen
Water 2026, 18(6), 753; https://doi.org/10.3390/w18060753 - 23 Mar 2026
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Abstract
Using perfluorooctanoic acid (PFOA) as a representative highly mobile solute to isolate hydrological controls, we investigated how slope influences the partitioning of vertical and lateral transport pathways. While vertical percolation has been widely examined using conventional column leaching tests, lateral transport driven by [...] Read more.
Using perfluorooctanoic acid (PFOA) as a representative highly mobile solute to isolate hydrological controls, we investigated how slope influences the partitioning of vertical and lateral transport pathways. While vertical percolation has been widely examined using conventional column leaching tests, lateral transport driven by topographic gradients remain insufficiently quantified under controlled conditions. Here, laboratory-scale inclined leaching experiments were conducted to resolve the distribution of solute transport among vertical leachate, lateral runoff, and solid-phase retention under systematically varied slope angles (0°, 4°, 9°, and 20°), flow regimes, and leaching volumes. Results show that solute migration shifted from vertical-dominated transport under flat conditions (91% at 0°) to lateral-dominated export at moderate slopes, with lateral pathways accounting for up to 75% of the recovered mass at 9°. This pathway shift was well described by an exponential partitioning model, f1(α) = fmax (1 − e), where fmax = 0.80 and k = 0.34°−1 (R2 = 0.97), indicating a critical crossover threshold at approximately 4° slope. Flow regime interacted with slope angle to modulate lateral transport efficiency: slower flow enhanced lateral export at moderate slopes, whereas faster flow promoted peak lateral transport under steeper conditions. In contrast, solid-phase retention remained consistently low (5–9%) across all treatments, indicating that the observed redistribution patterns were primarily governed by hydrological pathway partitioning rather than sorption processes. These results demonstrate that even modest topographic gradients can fundamentally alter solute transport pathways in sloped soils. The slope-dependent pathway partitioning framework developed here provides a process-based basis for incorporating lateral transport into hillslope hydrological models and for improving assessments of contaminant redistribution in both managed and natural landscapes. Full article
(This article belongs to the Section Hydrogeology)
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Article
A Mobility-Aware Zone-Based Key Management Scheme with Dynamic Key Refinement for Large-Scale Mobile Wireless Sensor Networks
by Abdelbassette Chenna, Djallel Eddine Boubiche, Abderrezak Benyahia, Homero Toral-Cruz, Rafael Martínez-Peláez and Pablo Velarde-Alvarado
Future Internet 2026, 18(3), 175; https://doi.org/10.3390/fi18030175 - 23 Mar 2026
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Abstract
Mobile Wireless Sensor Networks (MWSNs) enhance traditional wireless sensor networks by allowing sensor nodes to move, resulting in continuously changing network topologies. Although this mobility enables advanced applications such as disaster response, intelligent transportation systems, and mission-critical monitoring, it poses major challenges for [...] Read more.
Mobile Wireless Sensor Networks (MWSNs) enhance traditional wireless sensor networks by allowing sensor nodes to move, resulting in continuously changing network topologies. Although this mobility enables advanced applications such as disaster response, intelligent transportation systems, and mission-critical monitoring, it poses major challenges for secure and scalable key management in large-scale deployments. Most existing key management and key pre-distribution schemes are tailored to static or lightly mobile networks and therefore suffer from limited scalability, excessive memory consumption, inefficient key utilization, and increased vulnerability to node capture when applied to highly mobile environments. This paper proposes a mobility-aware, zone-based key management scheme that integrates an enhanced composite key distribution mechanism with dynamic key refinement. The network is partitioned into logical zones, each maintaining an independent key pool to confine security breaches and improve scalability. To adapt to mobility-induced topology changes, sensor nodes continuously refine their key rings by preserving only the cryptographic keys associated with persistent neighbor relationships. This selective retention strategy significantly reduces storage overhead while strengthening resilience against key compromise and unauthorized access. Comprehensive analytical modeling and performance evaluations demonstrate that the proposed scheme achieves higher secure connectivity, stronger resistance to node capture attacks, and improved scalability compared to existing approaches, particularly in dense and highly mobile MWSN scenarios. Full article
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