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  • Article
  • Open Access
4 Citations
3,855 Views
17 Pages

2-Hydroxyoleic Acid as a Self-Assembly Inducer for Anti-Cancer Drug-Centered Nanoparticles

  • Antonia I. Antoniou,
  • Giulia Nordio,
  • Maria Luisa Di Paolo,
  • Eleonora Colombo,
  • Beatrice Gaffuri,
  • Laura Polito,
  • Arianna Amenta,
  • Pierfausto Seneci,
  • Lisa Dalla Via and
  • Daniele Passarella
  • + 1 author

A potent nontoxic antitumor drug, 2-hydroxyoleic acid (6, 2OHOA) used for membrane lipid therapy, was selected as a self-assembly inducer due to its ability to form nanoparticles (NPs) in water. For this purpose, it was conjugated with a series of an...