Search Results (90)

Background/Objectives: Evidence on the role of muscle mechanical (myotonic) properties in athletic performance remains limited in young adult and sub-elite populations, particularly in American football, and sex-specific patterns of association are not well understood. This study aimed to investigate the associations between lower extremity myotonic properties and performance outcomes (strength and balance) in American football athletes, with a specific focus on sex-related differences and candidate predictors. Methods: A cross-sectional design was implemented involving 35 American football athletes (17 female, 18 male). Lower extremity muscle tone, stiffness, and elasticity were assessed using MyotonPRO. Strength parameters (lower limb, handgrip, back, and shoulder internal rotation) and balance performance (static and dynamic under eyes-open and eyes-closed conditions) were evaluated using standardized measurement protocols. Pearson correlation analysis was conducted to examine bivariate associations, followed by Least Absolute Shrinkage and Selection Operator (LASSO) regression to determine candidate predictors while addressing multicollinearity. Results: Male athletes exhibited significantly greater height, body mass, and BMI (p < 0.001), alongside elevated myotonic values compared to females. Correlation analyses indicated distinct sex-specific association patterns between myotonic properties and performance metrics. LASSO regression revealed a distinct sex-specific divergence in strength prediction: female strength was predominantly driven by proximal musculature (quadriceps and hamstring elasticity/stiffness), whereas male strength was anchored by distal musculature (gastrocnemius tone/stiffness). Furthermore, rigorous penalization shrunk nearly all balance coefficients to zero in both sexes, indicating that resting myotonic properties do not independently predict dynamic or static postural control. Conclusions: While lower extremity myotonic properties are candidate predictors of multi-regional strength via sex-specific proximal and distal strategies, they do not independently predict balance performance, suggesting postural control relies primarily on active motor recruitment rather than passive resting mechanics. Given the cross-sectional design of this study, causal inferences cannot be drawn, and these findings should be interpreted accordingly. The observed sex-specific differences may support consideration of individualized, sex-informed training strategies in American football athletes. Full article

Stenting is a minimally invasive treatment used in managing peripheral artery disease (PAD). However, clinical challenges persist, including in-stent thrombosis and restenosis, primarily driven by axial foreshortening or elongation and suboptimal balance between radial stiffness and flexibility inherent to conventional stent designs. This study proposes an innovative arrow-shaped geometry exhibiting zero Poisson’s ratio (ZPR) behaviour for 3D-printed self-expanding Nitinol stents. The complete stent deployment process was modelled using finite element analysis (FEA), including radial crimping and subsequent expansion to enable systematic parametric investigation while accounting for µ-3D printing constraints. Response surface methodology (RSM) rigorously evaluated mechanical performance, defining peak stress, chronic outward force (COF), radial resistive force (RRF), and foreshortening (FS) as constraint and objective functions within the optimisation framework. The optimised ZPR stent achieved favourable performance: extremely low foreshortening (|FS| ≤ 0.12%), representing outstanding axial stability compared with previously reported self-expanding stents, and a well-balanced radial response with ~50% higher radial strength than positive Poisson’s ratio (PPR) structures, while 16.67% lower than negative Poisson’s ratio (NPR) counterparts. These results highlight the ZPR stent’s capability to minimise axial deformation while maintaining adequate radial support, highlighting substantial potential for precise, stable deployment in PAD applications. Full article

Metabolic dysfunction-associated steatotic liver disease (MASLD) affects 25–30% of adults globally. Dietary sugar reduction is one of the key therapeutic targets, but elimination of sugar-sweetened foods may compromise adherence to calorie-restricted diets. Brazzein, a natural sweet protein that is 500–2000 times sweeter than sucrose, offers a promising substitute, yet clinical data in patients with MASLD are lacking. In a double-blind, randomized, two-period crossover trial, 103 adults with MASLD tasted iso-sweet vanilla ice cream sweetened with either brazzein or sucrose on two consecutive days. Overall impression and sensory attributes (appearance, color, aroma, taste, and texture) were rated on 5-point hedonic scales, and the percentage of the 100 g portion consumed was recorded. Brazzein-sweetened ice cream met the prespecified criteria for both non-inferiority and equivalence versus sucrose for overall impression. Top-2 box acceptance (ratings ≥ 4) was extremely high and nearly identical (96.1% for brazzein and 98.1% for sucrose). Mean consumption exceeded 98% of the portion for both products, with no significant difference between sweeteners. Secondary sensory ratings were closely similar, and multivariate analyses indicated highly overlapping sensory profiles. Exploratory subgroup analyses suggested consistent findings across most demographic and clinical characteristics, although participants with advanced liver fibrosis (LSM ≥ 9.6 kPa) showed numerically higher ratings for sucrose. In exploratory analyses, liver stiffness was associated with slightly lower intake at higher stiffness values. This study provides the first evidence that brazzein-sweetened ice cream maintains short-term sensory acceptability comparable to a conventional sucrose-sweetened product in adults with MASLD. These findings support further development and evaluation of brazzein-containing sugar-reduced foods, including repeated-exposure sensory studies and separate metabolic investigations. Full article

Geopolymeric concrete beams are gaining increasing attention as sustainable structural members. The paper presents an experimental investigation on the deflection and cracking behavior of geopolymeric recycled aggregate concrete (GRAC) beams, with emphasis on effects of the longitudinal reinforcement ratio and the recycled aggregate (RA) replacement ratio. Using digital image correlation (DIC) technology, the failure modes, load–deflection curves, deflection characteristics, stiffness, and cracking behavior were systematically analyzed. The results indicated that increasing the reinforcement ratio leads to the same trend in GRAC beams as that observed in ordinary reinforced concrete beams. At 50% RA replacement, GRAC beams exhibit improved cracking resistance, 13.41% higher cracking stiffness, 6.93% lower deflection, and enhanced ductility compared to specimens without RA, attributed to the enhanced RA–matrix interface. However, a further increase in the RA replacement ratio leads to poorer flexural performance of the GRAC beams. In addition, predictive models for cracking moment, stiffness, deflection, and maximum crack width of GRAC beams were proposed based on the experimental results, incorporating the plastic influence coefficient, the comprehensive coefficient for the average strain at the extreme compression zone of concrete and the maximum crack width correction factor. The calculated values agreed well with the test data, offering a basis for structural design and engineering application. Full article

This paper focuses on the characterization of the micro-leakage channel geometry in the flange-gasket rough contact interface of hazardous chemicals transport vehicles. This work represents the first step in a multi-physics simulation framework for optical-fiber-based micro-leakage monitoring. Directly establishing a full-scale contact model from micron-scale rough peaks and valleys to the decimeter-scale flange structure would lead to extremely high computational costs; a nonlinear contact model based on quasi-representative volume element (quasi-RVE) and quasi-periodic boundary condition (quasi-PBC) is proposed in this paper. Quasi-RVE refers to a local region selected from the overall rough surface. Unlike a traditional RVE that requires strict geometric periodicity, the quasi-RVE is only approximately consistent with the overall surface with respect to key morphological parameters and volume parameters. Quasi-PBC only imposes in-plane displacement compatibility constraint on the relative side boundary without imposing periodic constraints in the peak-valley height direction. In this paper, the average interface gap and its distribution are selected as the geometric descriptors of the micro-leakage channel, and the reliability of the contact model is verified by comparing with the existing experimental and numerical results. On this basis, the influences of surface roughness, gasket material and loading conditions on the geometric characteristics of the micro-leakage channel are further analyzed. The results show that the lower stiffness gasket is easier to fit with the rough flange surface under the same load conditions, so as to obtain a larger contact area and a smaller average gap. The quasi-RVE contact model established in this paper can effectively reduce the computational scale of contact analysis of the rough sealing interface, and provide reliable channel geometric information for subsequent micro-leakage fluid simulation and optical fiber signal response simulation. Full article

Background: Cardiometabolic diseases present a major challenge to contemporary public health. Diabetes mellitus (DM) is widely recognized as a strong cardiovascular risk factor. However, the utility of glycated hemoglobin percentage (HbA1c) for assessing cardiovascular health in individuals without DM remains uncertain. This study examines the association between HbA1c levels and both the presence and severity of subclinical atherosclerosis and arterial stiffness in non-diabetic individuals. Methods: A retrospective analysis was conducted on the data from 59 patients (72.88% female; mean age: 54.82 ± 17.34 years) who exhibited no signs of acute illness or exacerbation of chronic diseases. All patients were hospitalized in the Department of Internal Medicine, Angiology and Physical Medicine at the Medical University of Silesia in Katowice, Poland, between June 2022 and May 2024. HbA1c level determination, central blood pressure measurement with pulse wave analysis (PWA), carotid–femoral pulse wave velocity (cfPWV) measurement, and Doppler ultrasound of the carotid arteries and lower extremity arteries measuring the intima–media thickness (IMT) in the common carotid arteries (cIMT), common femoral arteries (cfIMT), and superficial femoral arteries (sfIMT) were performed. Spearman’s rank correlation test was applied for statistical analysis. Subsequently, a multivariate analysis model was constructed, adjusting for age, sex, body mass index (BMI), and smoking. Results: Among the assessed parameters, the strongest positive correlations were found between HbA1c and parameters such as cIMT (R = 0.532; p < 0.001), cfIMT (R = 0.63; p < 0.001), sfIMT (R = 0.539; p < 0.001), and cfPWV (R = 0.504; p < 0.001). In the multivariate analysis model, a significant relationship was found only between HbA1c and augmentation index normalized to a heart rate of 75 per minute (AIx75) (β = −0.286; 95% CI: −0.566, −0.006; p = 0.045). Conclusions: In summary, although HbA1c correlates with some parameters related to arterial stiffness and subclinical atherosclerosis in non-diabetic patients, most observed relationships are explained by confounding variables. Full article

Spar-type floating offshore wind turbines (FOWTs) operating in deep-sea environments are subjected to coupled wind and wave excitations spanning a wide frequency range, rendering single-frequency passive damping solutions inadequate. A folded-beam nonlinear energy sink (FB-NES) is proposed for broadband vibration suppression of spar-type FOWTs. The device employs pre-buckled elastic beam arms integrated with constrained layer damping patches, and a closed-form analytical relationship between the beam geometric parameters and the nonlinear stiffness coefficients is derived, enabling direct parameter design without iterative calibration. The pre-buckled geometry introduces a negative-stiffness mechanism that substantially lowers the targeted energy transfer (TET) threshold, ensuring device engagement under all normal operational sea states. A 14-degree-of-freedom aero-hydro-elastic model of the NREL 5 MW OC3-Hywind FOWT with the FB-NES is established via the Euler–Lagrange formulation and validated against OpenFAST. Based on the numerical results under operational and extreme parked load cases, the FB-NES achieves substantial broadband vibration reductions that grow monotonically with wave severity, consistently and substantially surpassing both the optimally tuned mass damper (TMD) and a conventional cubic nonlinear energy sink of equal mass. Wavelet analysis confirms that targeted energy transfer, rather than direct viscous damping, is the dominant energy dissipation mechanism. The FB-NES also maintains effective control over a wide frequency detuning range, demonstrating superior robustness compared to the TMD. Full article

This study investigates the thermal and vibration-attenuation performance of a novel 7-inch FPV drone frame manufactured from cast AZ31 magnesium alloy (MG), compared to 6061-T6 aluminum (AL) and carbon fiber (CF) composite structures under an extreme payload of 2 kg. Using quantitative spectral analysis of Blackbox flight logs, the research demonstrates that the MG frame provides superior system-level vibration damping, particularly under high-stress conditions. Under a 2 kg payload, the MG frame exhibited a 49% reduction in vibration power compared to the AL frame. Spectral data identified primary resonance peaks for the MG frame at 147 Hz (0 kg) and 204 Hz (2 kg), whereas the AL frame showed significantly higher frequency peaks at 179.5 Hz (0 kg) and 239.4 Hz (2 kg). Comparative modal hammer tests further validated these findings, with the magnesium design exhibiting lower impulse energy (0.22 mW/Hz) and faster decay than aluminum (0.24 mW/Hz). Thermal imaging analysis showed better motor cooling for the metallic frames; average motor temperatures on the magnesium frame (51.8 °C) and AL frame (50.3 °C) were significantly lower than on the CF structure (77.5 °C). The findings establish that AZ31 magnesium alloy offers an excellent synergy of lightweight stiffness and damping capacity, making it a viable alternative for heavy-duty FPV platforms requiring high signal integrity. Full article

Compliant mechanisms have contributed to many advances in soft robotics, and there is strong motivation to translate these ideas to assistive devices where adaptive motion at the human interface is required. This work presents novel reconfigurable compliant joints (RCJs) as a parameterized joint element for functional biomimicry in lower-extremity joints for prosthetic knees and ankle–foot orthoses, with concepts that extend to other limb joints. The RCJ uses a rigid hub and outer ring joined by an array of flexible links with centerlines defined by cubic Bézier curves. Link shapes are organized into four Bézier classes (A–D), with base types using 10, 12, or 14 uniformly distributed link slots and variants generated by modifying active-link count and distribution, forming a structured morphology space of 12 configurations for machine design. Dual-extrusion 3D-printed prototypes are characterized by a custom testing apparatus using a 2.2 kN load cell at 25 mm/s over a 0–90° rotation range across six recorded load cycles to measure torque–angle curves and stiffness under large deformations. Angle-dependent stiffness is evaluated over three fixed intervals (0–30°, 30–60°, and 60–90°) to quantify multi-stage behavior. A 2-dimensional corotational frame model and a Simscape Multibody model, including a rolling-contact knee configuration, use the same parameterization to relate geometry, nonlinear mechanics, and system-level motion. Experiments and simulations show multi-stage torque–angle profiles and predictable stiffness modulation across all configurations, with both magnitude and transition angle tunable through Bézier class and active-link distribution, positioning the RCJ as a CAD/CAE-compatible joint architecture for assistive devices or wearable robotic systems and a basis for advancing functional biomimicry in compliant mechanism design. Full article

With the rapidly growing global demand for clean energy, offshore wind power has become an important renewable energy source. To clarify how the principal dimensions affect the performance of a 15 MW-class floating wind turbine platform in 100 m water depth, this paper proposes a steel-concrete hybrid semi-submersible platform and systematically performs a parametric sensitivity analysis. The platform adopts a three-column configuration with heave tanks. The upper columns and cross braces are made of steel, while the lower hexagonal columns, pontoons, and heave tanks are constructed from concrete, significantly reducing steel consumption while satisfying structural and stability requirements. Focusing on three key design variables—draft, column spacing, and column diameter—this study establishes a unified normalized sensitivity analysis framework. It quantitatively evaluates their influence on platform mass, intact stability, natural periods, and fully coupled dynamic responses (including surge, heave, pitch motions, and mooring line tensions) under both operational and extreme conditions. The results reveal distinct roles of the principal dimensions in governing the platform dynamics: column spacing is the most sensitive parameter for tuning pitch response, restoring stiffness, and stability; increasing draft effectively suppresses heave and pitch responses but has only a limited effect on low-frequency surge motions; and column diameter strongly affects the natural periods of heave and pitch. Notably, dynamic responses exhibit significant nonlinear characteristics with variations in column diameter. When the diameter exceeds 110–120% of the baseline value, the peak pitch response under extreme sea states shows a deteriorating inflection point, accompanied by an accelerated surge in peak mooring loads. This indicates that excessive increases in column diameter may cause wave excitation forces to become dominant, thereby compromising the overall dynamic safety of the system. This paper identifies the governing geometric parameters for different motion modes and their control boundaries, providing a quantifiable and generalizable basis for the multi-objective collaborative design and cost reduction optimization of 15 MW steel-concrete hybrid semi-submersible floating wind turbine platforms. Full article

Background/Objectives: Lower extremity peripheral artery disease (PAD) is recognized as a significant public health issue, particularly due to its strong association with adverse cardiovascular events. Despite this, little attention has been given to its influence on left ventricular (LV) and left atrial (LA) function in patients with chronic heart failure (CHF). This study aims to examine the relationship between femoral plaque burden and structural and functional properties of the LV and LA in patients with CHF. Methods: Study design: cross-sectional observational single-center study. A total of 89 patients with CHF underwent comprehensive assessments, including duplex ultrasonography of lower extremity arteries and two-dimensional echocardiography. Analysis focused on evaluating femoral plaque burden, left ventricular deformation, and ventricular–arterial coupling. Results: Findings indicated that increased femoral plaque burden was associated with reductions in LA deformation and increases in LA stiffness. Similarly, there was evidence of impaired LV mechanics and elevated arterial loading, suggesting impaired ventricular–arterial coupling in patients with CHF and significant lower extremity atherosclerosis. Conclusions: Femoral plaque burden is closely linked to detrimental changes in LA and LV function, as well as disturbances in ventricular–arterial coupling, underscoring the importance of addressing lower extremity atherosclerosis in managing CHF patients. Full article

Background/Objectives: Neuromuscular functions (NMFs) encompass biomechanical and viscoelastic properties that are essential for coordinated movement and muscular control. While NMFs have been extensively investigated in the lower limb, normative data for the upper extremity remain limited, particularly regarding the interaction between neuromuscular properties, superficial fascia, and body composition. As body composition and fascial characteristics may influence neuromuscular behavior and the interpretation of mechanical measurements, this study aimed to establish reference values for upper limb NMF, analyze dominance-related differences, and investigate the relationship between superficial fascia thickness and body mass composition. Methods: A descriptive, non-experimental study was conducted involving 61 healthy adults (122 upper limbs). Assessments included body composition (bioimpedance), superficial fascia thickness (skinfolds), viscoelastic properties (MyotonPro), and isometric strength (handheld dynamometry). Standardized protocols were applied for all measurements. Comparisons were performed between sexes and between dominant and non-dominant limbs. Correlation analyses explored associations between NMF, adiposity, and fascia parameters. Results: Dominant limbs showed slightly greater strength; however, these differences were not statistically significant. Viscoelastic properties were largely symmetrical between limbs, with minimal dominance-related differences. Clear sex differences were observed: men demonstrated greater strength, lean mass, and increased stiffness, whereas women presented higher skinfold thickness and lower muscle tone. Weak correlations were identified between stiffness, relaxation, and strength, as well as between adiposity and superficial fascia thickness. Greater adipose thickness was associated with lower stiffness values in the triceps (rho= −0304; iC95% 0.041/0.528; p = 0.017). Conclusions: Upper limb neuromuscular properties exhibit high bilateral symmetry, with limb dominance influencing strength. Sex and body composition significantly modulate both viscoelastic and functional parameters. These findings provide normative reference values and highlight the relevance of considering body composition and fascial characteristics when assessing neuromuscular function in clinical and sports contexts. Full article

To address the technical challenge where traditional high-pressure, large-flow emulsion pump stations cannot adapt to the drastic flow rate changes in hydraulic supports due to the fixed displacement of their quantitative pumps—leading to frequent system unloading, severe impacts, and damage—this study proposes an intelligent flow control method based on the digital flow distribution principle for actively perceiving and matching support demands. Building on this method, a compact, electro-hydraulically separated prototype with stepless flow regulation was developed. The system integrates high-speed switching solenoid valves, a piston push rod, a plunger pump, sensors, and a controller. By monitoring piston position in real time, the controller employs an optimized combined regulation strategy that integrates adjustable duty cycles across single, dual, and multiple cycles. This dynamically adjusts the switching timing of the pilot solenoid valve, thereby precisely controlling the closure of the inlet valve. As a result, part of the fluid can return to the suction line during the compression phase, fundamentally achieving accurate and smooth matching between the pump output flow and support demand, while significantly reducing system fluctuations and impacts. This research adopts a combined approach of co-simulation and experimental validation to deeply investigate the dynamic coupling relationship between the piston’s extreme position and delayed valve closure. It further establishes a comprehensive dynamic coupling model covering the response of the pilot valve, actuator motion, and backflow control characteristics. By analyzing key parameters such as reset spring stiffness, piston cylinder diameter, and actuator load, the system reliability is optimized. Evaluation of the backflow strategy and delay phase verifies the effectiveness of the multi-mode composite regulation strategy based on digital displacement pump technology, which extends the effective flow range of the pump to 20–100% of its rated flow. Experimental results show that the system achieves a flow regulation range of 83% under load and 57% without load, with energy efficiency improved by 15–20% due to a significant reduction in overflow losses. Compared with traditional unloading methods, this approach demonstrates markedly higher control precision and stability, with substantial reductions in both flow root mean square error (53.4 L/min vs. 357.2 L/min) and fluctuation amplitude (±3.5 L/min vs. ±12.8 L/min). The system can intelligently respond to support conditions, providing high pressure with small flow during the lowering stage and low pressure with large flow during the lifting stage, effectively achieving on-demand and precise supply of dynamic flow and pressure. The proposed “demand feedforward–flow coordination” control architecture, the innovative electro-hydraulically separated structure, and the multi-cycle optimized regulation strategy collectively provide a practical and feasible solution for upgrading the fluid supply system in fully mechanized mining faces toward fast response, high energy efficiency, and intelligent operation. Full article

This study systematically investigated the influence of approach kinematics on the subsequent kinetics and power production strategies during the approach to running jumps with a single leg (ARJSL). Twenty-five physically active male university students performed ARJSL trials under two prescribed approach speeds (fast and slow) and three approach distances (3, 6, and 9 m) in a 2 × 3 within-subjects design. Three-dimensional motion capture synchronized with force platform data was used to quantify jump height (JH), vertical touchdown velocity (TDv), reactive strength index (RSI), peak joint power (hip, knee, and ankle), and joint stiffness. Significant approach speed × distance interactions were observed for JH (p = 0.006), TDv (p < 0.001), RSI (p = 0.014), ankle stiffness (p = 0.006), and peak power generation at all lower-limb joints (all p < 0.034). The results demonstrate that changes in approach strategy systematically alter the distribution of mechanical power among the hip, knee, and ankle joints, thereby influencing the effectiveness of horizontal-to-vertical momentum conversion during take-off. Notably, RSI and ankle stiffness were particularly sensitive to combined manipulations of speed and distance, highlighting their value as neuromechanical indicators of stretch–shortening cycle intensity and joint loading demands. In conclusion, ARJSL performance depends on finely tuned, speed- and distance-specific biomechanical adaptations within the lower extremity. These findings provide a constrained, joint-level mechanical characterization of how approach speed and distance interact to influence power redistribution and stiffness behavior during ARJSL, without implying optimal or performance-maximizing strategies. Full article

Background and Objectives: Sarcopenia and muscle wasting contribute significantly to functional decline in older adults, but differences in lower extremity muscle stiffness and gait variability between these groups are not yet fully understood. This study aimed to compare gait variability, and lower extremity muscle stiffness during contraction and relaxation in community-dwelling older adults classified as non-diseased, sarcopenic, and dynapenic. Materials and Methods: This cross-sectional study included 164 community-dwelling older adults classified as non-diseased, dynapenic, or sarcopenic, based on handgrip strength, 5-time sit-to-stand test, and skeletal muscle index. Spatiotemporal gait variability was measured at the participants’ preferred speed. Moreover, muscle thickness, as well as the contractile and relaxed stiffness, were measured for the rectus femoris (RF), biceps femoris (BF), tibialis anterior (TA), gastrocnemius medialis (GAmed), and lateralis (GAlat). Results: In dynapenic and sarcopenic groups, gait variability increased across most parameters, but only the step width coefficient of variation differed significantly between the dynapenic and sarcopenic groups. Contractile stiffness of the RF, BF, and GAlat was lower in both groups, with additional GAmed stiffness reduction in the sarcopenic group. Relaxed stiffness of the BF and GAmed was significantly higher in the sarcopenic group than in the dynapenic group. Conclusions: This study identified differences in muscle thickness, stiffness, and gait variability among non-diseased, dynapenic, and sarcopenic older adults. Step width variability, GAmed contractile stiffness, and BF and GAmed relaxed stiffness emerged as potential early indicators for distinguishing dynapenia from sarcopenia. These findings highlight the importance of assessing muscle quality—including both mass and stiffness characteristics—to better characterize early stages of age-related muscle decline and to inform targeted intervention strategies. Full article