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24,931 Results Found

  • Article
  • Open Access
1 Citations
1,527 Views
16 Pages

Few-shot relation extraction constitutes a critical task in natural language processing. Its aim is to train a model using a limited number of labeled samples when labeled data are scarce, thereby enabling the model to rapidly learn and accurately id...

  • Article
  • Open Access
23 Citations
13,153 Views
24 Pages

1 December 2014

Using three spatial network measures of “space syntax”, this correlational study describes four interaction-related behaviors among three groups of users in relation to visibility and accessibility of spaces in four adult intensive care units (ICUs)...

  • Article
  • Open Access
21 Citations
3,857 Views
23 Pages

In the era of digital economy and mobile internet, many platforms or brands have built various online or offline green communities to guide customers or fans to engage in green interactions. Obviously, community green interaction can enhance brand em...

  • Review
  • Open Access
8 Citations
4,272 Views
16 Pages

Peptide Targeting of PDZ-Dependent Interactions as Pharmacological Intervention in Immune-Related Diseases

  • Luis H. Gutiérrez-González,
  • Selma Rivas-Fuentes,
  • Silvia Guzmán-Beltrán,
  • Angélica Flores-Flores,
  • Jorge Rosas-García and
  • Teresa Santos-Mendoza

21 October 2021

PDZ (postsynaptic density (PSD95), discs large (Dlg), and zonula occludens (ZO-1)-dependent interactions are widely distributed within different cell types and regulate a variety of cellular processes. To date, some of these interactions have been id...

  • Article
  • Open Access
22 Citations
6,830 Views
15 Pages

In the context of pharmaceuticals, drug-drug interactions (DDIs) occur when two or more drugs interact, potentially altering the intended effects of the drugs and resulting in adverse patient health outcomes. Therefore, it is essential to identify an...

  • Article
  • Open Access
25 Citations
13,858 Views
16 Pages

Fundamental Power of Social Media Interactions for Building a Brand and Customer Relations

  • Ionica Oncioiu,
  • Sorinel Căpușneanu,
  • Dan Ioan Topor,
  • Attila Szora Tamaș,
  • Alina-Georgiana Solomon and
  • Tatiana Dănescu

The spread of social networks and the high level of penetration of digital content and mobile devices have created a society in which consumers expect constant communication from companies. In addition, communication on social media is often accompan...

  • Article
  • Open Access
5 Citations
5,585 Views
15 Pages

Strategies for Avoiding Typical Drug–Drug Interactions and Drug-Related Problems in Patients with Vascular Diseases

  • Klaus Peter Schmelzer,
  • Dominik Liebetrau,
  • Wolfgang Kämmerer,
  • Christine Meisinger and
  • Alexander Hyhlik-Dürr

17 April 2023

Background and objectives: Drug–drug interactions and drug-related problems in patients with vascular diseases are common. To date, very few studies have focused on these important problems. The aim of the present study is to investigate the mo...

  • Article
  • Open Access
936 Views
14 Pages

Gene–Environment Interactions of Apoptosis-Related Polymorphisms and Urinary Polycyclic Aromatic Hydrocarbon (PAH) Metabolites in Relation to Sperm Cell Apoptosis Among Men Attending Infertility Clinics

  • Shiting Yi,
  • Sitong Lin,
  • Jiabin Xie,
  • Zhihong Yang,
  • Junxia You,
  • Ximei Zhong,
  • Hui Yang,
  • Haiqing Lin,
  • Qian Wang and
  • Yingjun Chen
  • + 3 authors

31 December 2025

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental endocrine disruptors (EDCs) that enter the human body through respiratory, digestive, and dermal exposure. Prolonged exposure has been associated with adverse health outcomes, inclu...

  • Article
  • Open Access
5 Citations
2,816 Views
12 Pages

Genetic Dissection of Epistatic Interactions Contributing Yield-Related Agronomic Traits in Rice Using the Compressed Mixed Model

  • Ling Li,
  • Xinyi Wu,
  • Juncong Chen,
  • Shengmeng Wang,
  • Yuxuan Wan,
  • Hanbing Ji,
  • Yangjun Wen and
  • Jin Zhang

26 September 2022

Rice (Oryza sativa) is one of the most important cereal crops in the world, and yield-related agronomic traits, including plant height (PH), panicle length (PL), and protein content (PC), are prerequisites for attaining the desired yield and quality...

  • Article
  • Open Access
13 Citations
2,619 Views
21 Pages

24 September 2021

Human behaviors that greatly influence building energy consumption are stimulated by the indoor environment. However, the relative importance of different environmental factors remains unclear. Previous literature mostly focused on single behavior. H...

  • Article
  • Open Access
21 Citations
6,544 Views
25 Pages

21 March 2021

Autonomous vehicle technology increasingly allows drivers to turn their primary attention to secondary tasks (e.g., eating or working). This dramatic behavior change thus requires new input modalities to support driver–vehicle interaction, which must...

  • Article
  • Open Access
1 Citations
2,505 Views
24 Pages

29 May 2024

Social avoidance refers to active non-participation in social activities, which is detrimental to healthy interpersonal interaction for emerging adults. Social rejection is a kind of negative social evaluation from others making people feel social pa...

  • Article
  • Open Access
1,454 Views
20 Pages

4 March 2025

Background: Distant supervision employs external knowledge bases to automatically match with text, allowing for the automatic annotation of sentences. Although this method effectively tackles the challenge of manual labeling, it inevitably introduces...

  • Article
  • Open Access
1 Citations
3,095 Views
41 Pages

The purpose of this study is to examine the impact of integrity-related considerations, such as ethics, privacy, protection, security, and trust, on online consumer shopping intention within the interactive marketing environment. To achieve this, the...

  • Abstract
  • Open Access
1,833 Views
1 Page

Two Geogebra-based interactive applications to teach the Special Relativity Energy-Mass-Momentum relation are presented. They are useful tools to visualise the mathematical relation from a geometrical perspective, thus helping students facing calculu...

  • Review
  • Open Access
687 Views
12 Pages

ROGDI-Related Disorder Resulting from Disruption of Complex Interactive Neuro-Dental Developmental Networks: A Review and Description of the First Missense Variant

  • Sopio Gverdtsiteli,
  • Trine Bjørg Hammer,
  • Xenia Hermann,
  • Noemi Becser Andersen,
  • David Ros-Pardo,
  • Iñigo Marcos-Alcalde,
  • Paulino Gómez-Puertas,
  • Alan Henry Brook,
  • Asli Silahtaroglu and
  • Zeynep Tümer

14 October 2025

ROGDI-related neurodevelopmental and dental disorder (ROGDI-RD), also known as Kohlschütter–Tönz syndrome (KTZS, MIM #226750), is a rare condition characterized by developmental abnormalities affecting both the central nervous system...

  • Article
  • Open Access
5 Citations
3,746 Views
19 Pages

PON1 Status in Relation to Gulf War Illness: Evidence of Gene–Exposure Interactions from a Multisite Case–Control Study of 1990–1991 Gulf War Veterans

  • Lea Steele,
  • Clement E. Furlong,
  • Rebecca J. Richter,
  • Judit Marsillach,
  • Patricia A. Janulewicz,
  • Maxine H. Krengel,
  • Nancy G. Klimas,
  • Kimberly Sullivan and
  • Linda L. Chao

Background: Deployment-related neurotoxicant exposures are implicated in the etiology of Gulf War illness (GWI), the multisymptom condition associated with military service in the 1990–1991 Gulf War (GW). A Q/R polymorphism at position 192 of t...

  • Article
  • Open Access
1,402 Views
20 Pages

Leveraging Diverse Cell-Death Patterns to Decipher the Interactive Relation of Unfavorable Outcome and Tumor Microenvironment in Breast Cancer

  • Yue Li,
  • Ting Ding,
  • Tong Zhang,
  • Shuangyu Liu,
  • Jinhua Wang,
  • Xiaoyan Zhou,
  • Zeqi Guo,
  • Qian He and
  • Shuqun Zhang

Background: Programmed cell death (PCD) dynamically influences breast cancer (BC) prognosis through interactions with the tumor microenvironment (TME). We investigated 13 PCD patterns to decipher their prognostic impact and mechanistic links to TME-d...

  • Article
  • Open Access
3 Citations
2,617 Views
21 Pages

30 October 2022

The task of extracting drug entities and possible interactions between drug pairings is known as Drug–Drug Interaction (DDI) extraction. Computer-assisted DDI extraction with Machine Learning techniques can help streamline this expensive and ti...

  • Article
  • Open Access
50 Citations
9,213 Views
15 Pages

This study examined the additive and interactive effects of role stress and emotional intelligence for predicting engagement among 288 teachers. Emotional intelligence and engagement were positively associated. Role ambiguity and role conflict showed...

  • Article
  • Open Access
3 Citations
2,451 Views
19 Pages

Additive and Interactive Associations of Environmental and Sociodemographic Factors with the Genotypes of Three Glutathione S-Transferase Genes in Relation to the Blood Arsenic Concentrations of Children in Jamaica

  • Mohammad H. Rahbar,
  • Maureen Samms-Vaughan,
  • Yuansong Zhao,
  • Sepideh Saroukhani,
  • Sheikh F. Zaman,
  • Jan Bressler,
  • Manouchehr Hessabi,
  • Megan L. Grove,
  • Sydonnie Shakspeare-Pellington and
  • Katherine A. Loveland

Arsenic (As) is a metalloid that has been classified as a xenobiotic with toxic effects on human beings, especially on children. Since the soil in Jamaica contains As, dietary intake is considered the main source of As exposure in Jamaicans. In addit...

  • Article
  • Open Access
8 Citations
4,089 Views
24 Pages

The identification of drug–drug and chemical–protein interactions is essential for understanding unpredictable changes in the pharmacological effects of drugs and mechanisms of diseases and developing therapeutic drugs. In this study, we...

  • Article
  • Open Access
7 Citations
8,048 Views
11 Pages

Interactive Associations between Physical Activity and Sleep Duration in Relation to Adolescent Academic Achievement

  • Denver M. Y. Brown,
  • Carah Porter,
  • Faith Hamilton,
  • Fernanda Almanza,
  • Christina Narvid,
  • Megan Pish and
  • Diego Arizabalo

Purpose: The present study aimed to examine independent and interactive associations between physical activity and sleep duration with adolescent academic achievement. Methods: This cross-sectional study used data from the 2019 cycle of the US-based...

  • Article
  • Open Access
7 Citations
3,218 Views
15 Pages

5 December 2022

Task-modality has been found to constrain the production of LREs in adults and children. However, there are no studies with young learners that have offered a comprehensive analysis of LREs. To this end, this paper will examine the effect of task-mod...

  • Article
  • Open Access
23 Citations
14,423 Views
15 Pages

In view of the rapid development of information and communication technologies, the present study sheds light on how work-related smartphone use during non-work time affects employees’ subsequent working day. Specifically, we examine work-relat...

  • Article
  • Open Access
7 Citations
3,560 Views
16 Pages

Soybean Mosaic Virus 6K1 Interactors Screening and GmPR4 and GmBI1 Function Characterization

  • Ting Hu,
  • Hexiang Luan,
  • Liqun Wang,
  • Rui Ren,
  • Lei Sun,
  • Jinlong Yin,
  • Hui Liu,
  • Tongtong Jin,
  • Bowen Li and
  • Haijian Zhi
  • + 1 author

Host proteins are essential during virus infection, and viral factors must target numerous host factors to complete their infectious cycle. The mature 6K1 protein of potyviruses is required for viral replication in plants. However, the interaction be...

  • Article
  • Open Access
4 Citations
3,485 Views
21 Pages

Oscillatory EEG Signatures of Affective Processes during Interaction with Adaptive Computer Systems

  • Mathias Vukelić,
  • Katharina Lingelbach,
  • Kathrin Pollmann and
  • Matthias Peissner

31 December 2020

Affect monitoring is being discussed as a novel strategy to make adaptive systems more user-oriented. Basic knowledge about oscillatory processes and functional connectivity underlying affect during naturalistic human–computer interactions (HCI...

  • Article
  • Open Access
7 Citations
4,750 Views
8 Pages

Sensory Reweighting for Postural Control in Older Adults with Age-Related Hearing Loss

  • Lydia Behtani,
  • Daniel Paromov,
  • Karina Moïn-Darbari,
  • Marie-Soleil Houde,
  • Benoit Antoine Bacon,
  • Maxime Maheu,
  • Tony Leroux and
  • François Champoux

23 November 2023

There is growing evidence linking hearing impairments and the deterioration of postural stability in older adults. To our knowledge, however, no study to date has investigated the effect of age-related hearing loss on the sensory reweighting process...

  • Article
  • Open Access
23 Citations
5,445 Views
11 Pages

Drug-Related Problems and Polypharmacy in Nursing Home Residents: A Cross-Sectional Study

  • Raquel Díez,
  • Raquel Cadenas,
  • Julen Susperregui,
  • Ana M. Sahagún,
  • Nélida Fernández,
  • Juan J. García,
  • Matilde Sierra and
  • Cristina López

At present, 19.2% of the Spanish population is aged 65 or older. Polypharmacy is a frequent condition among the elderly, especially in those living in nursing homes, which is associated with adverse outcomes, such as adverse drug events or drug-drug...

  • Article
  • Open Access
8 Citations
8,500 Views
27 Pages

Abstract: The exploration of multidimensional datasets of all possible sizes and dimensions is a long-standing challenge in knowledge discovery, machine learning, and visualization. While multiple efficient visualization methods for n-D data analysis...

  • Review
  • Open Access
26 Citations
5,295 Views
30 Pages

1 January 2021

A growing number of soundscape studies involving audiovisual factors have been conducted; however, their bimodal and interactive effects on indoor soundscape evaluations have not yet been thoroughly reviewed. The overarching goal of this systematic r...

  • Article
  • Open Access
7 Citations
3,872 Views
16 Pages

26 January 2021

In multiple related time series prediction problems, the key is capturing the comprehensive influence of the temporal dependencies within each time series and the interactional dependencies between time series. At present, most time series prediction...

  • Article
  • Open Access
4 Citations
3,297 Views
17 Pages

Unveiling Drug-Drug Interactions in Dental Patients: A Retrospective Real-World Study

  • Daiana Colibășanu,
  • Sebastian Mihai Ardelean,
  • Florina-Diana Goldiș,
  • Maria-Medana Drăgoi,
  • Sabina-Oana Vasii,
  • Tamara Maksimović,
  • Șerban Colibășanu,
  • Codruța Șoica and
  • Lucreția Udrescu

9 June 2025

Background: Drug-drug interactions (DDIs) are a growing safety concern in dental care, particularly among patients with comorbidities and polypharmacy. However, real-world data (RWD) on the prevalence and severity of DDIs in dental settings remain sc...

  • Article
  • Open Access
2,435 Views
24 Pages

What Drives Hospitality Employees’ Trust in Service Robots?

  • Minkyung Park,
  • Diamond A. Andress,
  • Jae Hyup Chang,
  • Andy Lee and
  • Chung Hun Lee

4 November 2025

As service robots become more prevalent in hospitality settings, understanding what shapes employees’ trust in these technologies is essential for fostering effective human–robot collaboration. Despite extensive research on customer trust...

  • Article
  • Open Access
1 Citations
1,815 Views
22 Pages

23 August 2024

With the development of large language model technologies, the capability of social robots to interact emotionally with users has been steadily increasing. However, the existing research insufficiently examines the influence of robot stance attributi...

  • Article
  • Open Access
7 Citations
3,500 Views
21 Pages

23 April 2024

To achieve the “double carbon” goal, green value co-creation has been paid more and more attention. However, the role of users in green value co-creation, which is a vital aspect, could be overlooked. Understanding the internal mechanism...

  • Review
  • Open Access
14 Citations
8,100 Views
23 Pages

29 September 2015

Phosphatidylinositol 3-kinase-related kinases (PIKKs) play vital roles in the regulation of cell growth, proliferation, survival, and consequently metabolism, as well as in the cellular response to stresses such as ionizing radiation or redox changes...

  • Article
  • Open Access
1 Citations
1,656 Views
18 Pages

Impact of Drp1 Loss on Organelle Interaction, Metabolism, and Inflammation in Mouse Liver

  • Lixiang Wang,
  • Seiji Nomura,
  • Nao Hasuzawa,
  • Sadaki Yokota,
  • Ayako Nagayama,
  • Kenji Ashida,
  • Junjiro Rikitake,
  • Yoshinori Moriyama,
  • Masatoshi Nomura and
  • Ken Yamamoto

8 May 2025

Dynamin-related protein 1 (Drp1) is a crucial player in mitochondrial fission and liver function. The interactions between mitochondria, endoplasmic reticulum (ER), and lipid droplets (LDs) are fundamental for lipid metabolism. This study utilized li...

  • Article
  • Open Access
11 Citations
3,068 Views
29 Pages

To reduce greenhouse gas emissions, conserve the environment, and reduce dependency on fossil fuels, the transition from fossil energy to renewable energy is deemed essential. Several companies around the globe, especially big conglomerates, were pio...

  • Article
  • Open Access
3 Citations
3,976 Views
9 Pages

A Glance into MTHFR Deficiency at a Molecular Level

  • Castrense Savojardo,
  • Giulia Babbi,
  • Davide Baldazzi,
  • Pier Luigi Martelli and
  • Rita Casadio

23 December 2021

MTHFR deficiency still deserves an investigation to associate the phenotype to protein structure variations. To this aim, considering the MTHFR wild type protein structure, with a catalytic and a regulatory domain and taking advantage of state-of-the...

  • Article
  • Open Access
49 Citations
4,008 Views
20 Pages

Characteristics and Mechanisms of Asphalt–Filler Interactions from a Multi-Scale Perspective

  • Wenyi Xu,
  • Xin Qiu,
  • Shanglin Xiao,
  • Haojue Hong,
  • Feng Wang and
  • Jie Yuan

17 June 2020

Asphalt mastic plays an important role in asphalt mixtures for pavement engineering. Understanding the asphalt–filler interaction behavior is essential to improve the pavement performance of asphalt mastics. The objective of this paper was to e...

  • Review
  • Open Access
6 Citations
2,289 Views
18 Pages

26 July 2025

Cadmium is widely recognized as an important environmental toxicant that may give rise to kidney dysfunction, bone disease, and cancer in humans and animals. Kidney dysfunction occurs at very low exposures and is often considered as the most sensitiv...

  • Article
  • Open Access
8 Citations
3,976 Views
20 Pages

Genome-Wide Association Study Reveals Candidate Genes for Root-Related Traits in Rice

  • Jun Xiang,
  • Chaopu Zhang,
  • Nansheng Wang,
  • Zhaojie Liang,
  • Zheng Zhenzhen,
  • Lunping Liang,
  • Hongyan Yuan and
  • Yingyao Shi

21 September 2022

Root architecture is a determinant factor of drought resistance in rice and plays essential roles in the absorption of water and nutrients for the survival of rice plants. Dissection of the genetic basis for root structure can help to improve stress-...

  • Article
  • Open Access
1 Citations
2,195 Views
18 Pages

Asoprisnil as a Novel Ligand Interacting with Stress-Associated Glucocorticoid Receptor

  • Ovinuchi Ejiohuo,
  • Donald Bajia,
  • Joanna Pawlak and
  • Aleksandra Szczepankiewicz

30 November 2024

Background/objective: The glucocorticoid receptor (GR) is critical in regulating cortisol production during stress. This makes it a key target for treating conditions associated with hypothalamic–pituitary–adrenal (HPA) axis dysregulation...

  • Article
  • Open Access
14 Citations
3,245 Views
17 Pages

31 March 2020

LM 25 is an aluminum alloy that has numerous applications such as in the manufacturing of automobile components and food industries, and especially in marine and seawater applications, due to its exceptional properties. An exertion has been taken for...

  • Article
  • Open Access
1 Citations
1,754 Views
13 Pages

18 December 2023

The rhizosphere bacteria Bacillus velezensis GJ-7, as a biological control agent (BCA), has significant biological control effects on Meloidogyne hapla, and has strong colonization ability in the root of Panax notoginseng. In this study, we conducted...

  • Article
  • Open Access
5 Citations
3,054 Views
10 Pages

22 April 2021

Temperature is considered one of the crucial environmental elements in plant pathological interactions, and previous studies have indicated that there is a relationship between temperature change and host–pathogen interactions. The objective of this...

  • Article
  • Open Access
8 Citations
3,371 Views
17 Pages

17 December 2020

Autonomous vehicles (AV) increasingly allow drivers to engage in secondary tasks such as eating or working on a laptop and thus require easy and reliable interaction inputs to facilitate communication between the driver and the vehicle. However, driv...

  • Systematic Review
  • Open Access
156 Views
12 Pages

Towards a Unified Terminology for Implant-Influenced Fractures: Implications for Musculoskeletal and Muscle–Implant Interaction Research

  • Giacomo Papotto,
  • Ignazio Prestianni,
  • Enrica Rosalia Cuffaro,
  • Alessio Ferrara,
  • Marco Ganci,
  • Calogero Cicio,
  • Alessandro Pietropaolo,
  • Marco Montemagno,
  • Saverio Comitini and
  • Rocco Ortuso
  • + 1 author

15 January 2026

Background: The global increase in orthopedic implant use—both for trauma fixation and arthroplasty—has profoundly transformed musculoskeletal surgery. As a consequence, fractures occurring in the presence of implants have become more fre...

  • Article
  • Open Access
27 Citations
8,826 Views
17 Pages

Theoretical Foundations to the Impact of Dog-Related Activities on Human Hedonic Well-Being, Life Satisfaction and Eudaimonic Well-Being

  • Ana Maria Barcelos,
  • Niko Kargas,
  • John Maltby,
  • Sophie Hall,
  • Phil Assheton and
  • Daniel S. Mills

Cross-sectional comparisons of well-being between dog owners and non-owners commonly generate inconsistent results. Focusing on the uniqueness of the relationship might help address this issue and provide a stronger foundation for dog-related psychot...

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