Search Results (1,162)

Background/Objectives: Pulsed Electric Field (PEF) therapy is a non-thermal ablation technique that induces immunogenic cell death through high-voltage, short-duration electrical pulses. This may enhance antitumor immunity by releasing intact tumor antigens and potentially generating abscopal effects. We report early outcomes in 32 patients with primary lung cancer or lung oligometastases treated with PEF at a community hospital, with a median (IQR) follow-up of 180.5 (158–207) days. Methods: This retrospective study collected demographics, cancer type, treatment response, and outcomes for patients undergoing PEF ablation. Tumor response was assessed using Sum of Longest Dimensions per RECIST 1.1 to classify progressive disease, stable disease, partial response, or complete response. Volumetric changes were additionally analyzed using RECIST 1.1 percentage thresholds applied to change in volume. Results: At initial 3-month follow-up, 26 of 32 patients demonstrated stable disease, partial response, or complete response, suggesting an 81.25% disease control rate/clinical benefit rate among this cohort. Among patients with Stage III–IV disease, 27.6% (8/29) showed radiographic evidence of a possible abscopal response. At 6 months, 24 of 32 patients remained alive and evaluable, with 62.5% (20/32) maintaining stable disease, partial response, or complete response. Conclusions: Despite patients having progressive disease on systemic therapy before PEF, early outcomes post-ablation suggest favorable local control and potential immunologic benefit. Patients with early-stage disease not receiving systemic therapy also showed excellent local response. Patients tolerated therapy very well. Clinical benefit was observed in 81.25% of patients at 3 months and 62.5% at 6 months, with radiographic evidence of possible abscopal responses in 27.6% of advanced-stage patients, supporting further exploration of the immunogenic potential of PEF demonstrated in preclinical and emerging clinical studies. Full article

Multi-output, single-switch, hard-switched Pulse-Width Modulated (PWM) converters suffer from high switching losses, which strictly limit their power density. To significantly reduce these losses, this work proposes a novel family of non-isolated multi-output DC-DC converters based on a quasi-resonant, single-switch cell operating in the megahertz (MHz) range. Sixteen configurations are derived to enhance power density and minimize component stress. A comprehensive analysis derives the fundamental analytical expressions for operation, switching conditions, and power flow. These expressions form the basis of a design tool that facilitates parametric component selection and optimization. The developed tool calculates voltage and current stresses, alongside power losses, using RMS current analysis and user-defined parameters such as ESR and semiconductor non-idealities. Finally, experimental results from prototypes operating at approximately 1 MHz in both full-wave and half-wave modes, with step-up and step-down capabilities, confirm the accuracy of the analytical design tool and the simulation model. Full article

In high-frequency 400 V/48 V matrix planar LLC resonant converters for data center power supplies, enlarged interwinding parasitic capacitance can induce significant transformer-related common-mode (CM) displacement currents. However, the effects of secondary-side rectifier commutation and local winding position on the resulting CM spikes have not been sufficiently clarified. This paper establishes a unified analytical expression for the transformer-related CM current in a converter with a half-bridge primary and a full-bridge synchronous-rectifier (SR) secondary. The analysis shows that asynchronous SR commutation shifts the secondary reference potential and introduces additional excitation through the interwinding parasitic capacitances, thereby producing double-pulse CM current spikes. The unequal spike amplitudes among different secondary-side rectifier units are further explained by the combined effects of local winding position and distributed parasitic coupling. Based on these findings, a shielding-layer scheme was then proposed and verified on a 400 V/48 V, 300 kHz, 3 kW prototype. The experimental results show average reductions of about 15 dB over 150 kHz–800 kHz and 20 dB over 800 kHz–6.5 MHz in the CM voltage spectrum, whereas the prototype achieves a peak efficiency of 97.78%. Full article

Dual three-phase interior permanent magnet synchronous motors (DT-IPMSMs) are widely used in high-power and high-reliability applications, and accurate rotor polarity identification at startup is a critical prerequisite for their stable and efficient operation. This study aims to address the problem of initial position acquisition during the startup of DT-IPMSMs by proposing a simple and fast rotor polarity identification method. The proposed method is based on the high-frequency square-wave voltage injection (HFSWVI) in the vector space decomposition (VSD) space, where both the current and voltage are injected into the d-axis. The single-pulse direct current (DC) injection is used to alter the magnetic saturation. Then, the change rates of the d-axis high-frequency response current are compared before and after DC injection to identify the rotor magnetic polarity. In addition, a moving average filter (MAF) is applied to suppress the fluctuations in the current change rate, which increases the accuracy of polarity identification. Moreover, a simple compensation technique is designed to make the estimated d-axis current change smoothly when the estimated angle changes from N-pole to S-pole. The effectiveness of the proposed method is proved by the experimental results in both standstill and free-running states for the prototyped DT-IPMSMs. This method provides a practical and efficient solution for initial position identification of DT-IPMSMs, contributing to the advancement of control technology for dual three-phase motor systems in related fields. Full article

This article presents the design and characterization process of a lightweight Vivaldi antenna for high-voltage ultra-wideband systems. The proposed antenna consists of two radiating arms with different exponential curves on their inner and outer edges fed with an insulated-coplanar-plates transmission line. Weight reduction is achieved by implementing the antenna with sheets composed of a polyester layer between two aluminum layers, with a polylactic acid insulator inserted between the arms. The reflection coefficient of the implemented antenna demonstrates an impedance bandwidth ranging from 0.61 GHz to 3.44 GHz. High-voltage operation of up to 12.4 kV is also experimentally demonstrated. In addition to satisfying the high-voltage and ultra-wideband operational requirements, the proposed antenna is shown to achieve, among antennas with comparable characteristics, the most effective combination of low minimum operating frequency and low weight. The transfer function between the voltage applied to the antenna, $V_s$, and the radiated electric field, $E_r$, is measured. Using this transfer function, the radiated electric field is calculated for an input voltage pulse with a rise time of 110 ps to confirm the antenna’s capability of producing radiated pulses with low distortion. The calculated radiated electric field pulse closely matches the results obtained with full-wave simulation. To assess the similarity between the radiated and applied pulses, the pulse width stretch ratio is calculated, yielding a variation of 3.86% for the direction of maximum gain and 9.36% for 30° in the H-plane of the antenna. This feature is desirable for EMC, EMI and sensing applications. The antenna is also characterized in the frequency domain, achieving a maximum gain of 10.09 dBi at 3.63 GHz and a 30° 3 dB beamwidth for ultra-wideband pulses. Full article

High-frequency endoscopic ultrasound is crucial for the early diagnosis of gastrointestinal tumors. However, achieving high axial resolution, deep tissue signal-to-noise ratio, and real-time data processing simultaneously remains a significant challenge in hardware implementation. This paper proposes a miniaturized real-time high-frequency imaging system based on the Xilinx Artix-7 FPGA. To overcome attenuation limitations of high-frequency signals, we employ a 4-bit Barker code-encoded excitation scheme coupled with a programmable ±100 V high-voltage transmission circuit. This effectively enhances echo energy without exceeding peak voltage safety thresholds. At the receiver end, the system utilizes a multi-channel analog front end integrated with mixed-signal time-gain compensation technology. Furthermore, to address transmission bottlenecks for massive echo data, we designed a Low-Voltage Differential Signaling (LVDS) interface logic based on dynamic phase calibration, ensuring stable, high-speed data transfer to the host computer via USB 3.0. Experimental results with a 20 MHz transducer demonstrate that the system achieves real-time B-mode imaging at 30 frames per second. Phantom testing revealed an axial resolution of 0.13 mm, enabling clear differentiation of 0.1 mm microstructures. Compared to conventional single-pulse excitation, coded excitation technology improved signal-to-noise ratio (SNR) by approximately 4.5 dB at a depth of 40 mm. These results validate the system’s capability for high-precision deep imaging suitable for clinical endoscopy applications, delivered in a compact, low-power form factor. Full article

A novel modular multilevel converter (MMC)-based spark-gap trigger generator for high-voltage pulsed-power applications has been developed and presented in this work. It fully exploits the inherent modularity of MMC topology to generate high-voltage trigger pulses in a flexible and scalable manner. A prototype based on insulated gate bipolar transistors (IGBTs) was constructed to effectively trigger the breakdown of the spark gaps of a Marx Bank consisting of four capacitors charged to 50 kV. It is characterized by a fast rise time and produces pulses of 15 kV with a duration of ~200 ns. Using semiconductors and foil capacitors, the new trigger generator successfully replaces the thyratron-based generator. Full article

This work introduces a systematic small-signal modeling framework for a family of non-isolated high step-up dc–dc converters based on the multistate switching cell (MSSC) operating in continuous conduction mode (CCM). By analyzing the current and voltage waveforms associated with the switching cell, an averaged circuit model based on the pulse width modulation (PWM) switch technique is derived. The proposed method relies only on basic circuit principles, avoiding complex matrix manipulations. To validate the theoretical assumptions, a non-isolated dc–dc boost converter with a high voltage gain is evaluated, and its response is compared with that of the derived model. Full article

Improving the quality of welded joints, as well as the advancement of equipment and materials, inevitably requires deep theoretical knowledge of the physical phenomena occurring in the arc column and in the cathode and anode regions. Achievements in the field of controlling metal transfer at the micro- and nanoscale through the regulation of current and voltage in welding power sources have encountered the problem of the formation of cathode and anode spots, which affect the stability of welding arcs and the quality of the weld. Under short current pulses and pauses, the stability of the arc discharge depends on the ability to form a cathode spot, melt the wire metal, and transfer it through the arc column. In this article, based on the generalization of known experimental facts and studies performed using a high-speed camera, it is shown that the current-carrying channel of the electric arc has a discrete structure consisting of a multitude of thin channels through which the main discharge current flows. The cathode spot of the arc discharge represents a highly heated and brightly luminous region on the cathode surface. Electron emission sustaining the discharge and the removal of cathode material occur from this region. A new method is proposed for investigating the reverse side of the cathode spot, which makes it possible to identify a structure consisting of individual cells or fragments of the cathode spot. For the first time, anode spots recorded with a high-speed camera are presented. An analysis of the spot structure is carried out. The parameters influencing the mobility of cathode and anode spots are determined. Based on the obtained experimental facts, a hypothesis is proposed regarding the non-uniform structure of cathode and anode spots in the arc discharge. Full article

Pulse Width Modulated (PWM) voltage source inverters are widely used to power induction motors in industrial applications. However, they generate common-mode voltage (CMV), which induces high shaft voltages and bearing currents, leading to premature motor failures. This paper proposes a novel active cancellation method to compensate for the CMV in high-voltage induction motor drives. The method utilizes Y-configured resistors for CMV detection and a push–pull amplifier with MOSFETs to generate reproduced CMV (RCMV). The RCMV is applied to the motor frame via an isolation transformer, effectively reducing the CMV-induced common-mode current (CMC). The proposed method achieves a significant reduction in the CMC, from 1.5 A to 4 mA peak-to-peak in a simulation and from 2.7 A to 57 mA peak in experiments with a 1.1 kW, 415 V/60 Hz motor. This cost-effective approach enhances motor drive reliability and mitigates electromagnetic interference (EMI), making it suitable for high-voltage applications. Full article

Silicone gel packaging for high-voltage power devices suffers severe insulation degradation under complex conditions involving sustained high voltages and steep pulses. DC superimposed pulse electric fields are the primary cause. However, existing research lacks a systematic quantitative analysis of key influencing factors. Motivated by this inadequacy, this study quantified the effects of four core factors via control variable-based electrical tree experiments and revealed the microscopic mechanism through charge vibration experiments. Results indicate that pulse voltage slew rate is the most critical factor, as the impact of altering the pulse voltage slew rate on the parameters of the electrical tree exceeds 200%, while the impacts of altering the superimposed DC amplitude and duty cycle are 49.92% and 77.56%, respectively. Further discussion demonstrates that pulse voltage slew rate reflects the charge dynamic behaviors, while DC amplitude and duty cycle reflect charge static accumulation, with charge dynamic behaviors posing a more significant effect. This work clarifies key control parameters for silicone gel insulation degradation and the intrinsic influence chain from influencing factors to molecular stress, charge dynamic behaviors, electrical tree growth and silicone gel insulation degradation, providing theoretical support and technical guidance for optimizing the design and enhancing the reliability of silicone gel in power electronic devices packaging insulation. Full article

In recent years, industrial systems and power electronic equipment have imposed increasingly stringent requirements on power quality, and therefore, the realization of a high-quality power supply has garnered extensive research attention. Selective harmonic elimination pulse width modulation (SHEPWM) features superior harmonic suppression performance and can effectively attenuate specific sub-harmonics; however, solving the associated system of nonlinear transcendental equations remains a critical challenge, primarily due to its inherent computational complexity and the risk of convergence to local optima. To address these limitations, we propose a multi-strategy enhanced chaotic black-winged kite algorithm (CMBKA). The proposed CMBKA integrates three synergistic optimization strategies: logistic–tent chaotic mapping for uniform population initialization, golden sine strategy to balance global exploration and local exploitation, and Monte Carlo perturbation to avoid convergence to local optima. In contrast to BKA, the proposed CMBKA achieves markedly higher calculation accuracy for switching angles, which is systematically validated on a five-level modified packed U-cell (MPUC) inverter platform. Experimental results verify that the proposed CMBKA achieves a lower total harmonic distortion (THD) than does the BKA, while the targeted specific sub-order harmonics are effectively suppressed to below 0.05%, with a maximum voltage deviation of 2.3% between the simulation results and experimental hardware tests. This work provides a high-precision SHEPWM solution for multilevel inverters, offering significant potential for renewable energy systems requiring minimal harmonic pollution and high power density. Full article

Large-scale integration of electric vehicle charging stations into the energy distribution network introduces highly variable power demands leading to additional voltage drops, increase in power losses, and quality degradation. Conventional mitigation strategies, including reactive power control only and multi-loop dq-axis-based controllers, often suffer from high computational complexity and limited flexibility for simultaneous active and reactive power control. This study presents a delay-modulated pulse width modulation control scheme for coordinated active and reactive power control in an energy distribution network with high penetration of electric vehicle charging load that are both time-varying and site-shifting in nature. The scheme uses a unified system comprising a solar photovoltaic array, battery storage system and a distribution STATCOM system. In this scheme, the control of active and reactive power is directly incorporated in the PWM pulse generation process by adding an adjustable delay parameter that controls the phase shift between the inverter current and the grid voltage. The proposed scheme is validated using a representative distribution feeder supplying the electric vehicle charging loads. The result illustrates that the feeder receiving end bus voltage drop is about 35% lower, the active power losses are about 40% lower, and the total harmonic distortion is at about 3%, which is within the IEEE 519 limit recommendations. Thus, the proposed control scheme is seen to be effective and computationally efficient, providing a scalable solution for real-time voltage regulation and power loss reduction. Full article

In electric vehicle (EV) charging systems, DC series arc faults, due to their high concealment and severe hazard, have become one of the important causes of electric vehicle fire accidents. An improved hybrid arc fault model of a charging system was established in Simulink for preliminary study. The results show that the high-frequency noise generated by arc faults affects the output voltage quality of the charger, and this noise is conducted to the battery voltage. Arc faults in a real electric vehicle charging experimental platform were further investigated, where it was found that, during arc fault events, the charging system provides no alarm indication, and the current signals exhibit significant large-amplitude random disturbances and nonlinear fluctuations. Moreover, under normal conditions during vehicle charging startup and the pre-charge stage, the current waveforms also present high-pulse spike characteristics similar to arc faults. Finally, a carefully designed deep neural network-based arc fault detection algorithm, Arc_TCNsformer, is proposed. The current signal samples are directly input into the network model without manual feature selection or extraction, enabling end-to-end fault recognition. By integrating a temporal convolutional network for multi-scale local feature extraction with a sparse Transformer for contextual information aggregation, the proposed method achieves strong robustness under complex charging noise environments. Experimental results demonstrate that the algorithm not only provides high detection accuracy but also maintains reliable real-time performance when deployed on embedded edge computing platforms. Full article

This study presents the engineering design and system-level modeling of a high-frequency power supply architecture for electrostatic precipitators intended to improve particulate removal efficiency and operational stability. Atmospheric air pollution by fine particulate matter (PM2.5) remains one of the most critical challenges in environmental protection and public health. Although electrostatic precipitators (ESPs) are widely used for industrial gas cleaning, the efficiency and stability of conventional 50 Hz power supplies are limited under conditions of strongly nonlinear corona discharge and high-resistivity dust. This paper presents the development and investigation of an advanced high-frequency power supply system for electrostatic precipitators based on a coupled electrical–electrophysical mathematical model. The work follows an engineering design methodology that integrates converter topology selection, electrophysical modeling of corona discharge, and control-oriented system optimization. The proposed model provides a unified description of electric field formation, space charge accumulation, ion transport, and particle motion in the corona discharge region. The simulation results show that in the operating voltage range of 10–100 kV, the electric field strength reaches (2–5)·10⁶ V/m, the ion concentration stabilizes in the range of 10¹³–10¹⁵ m⁻³, and the particle drift velocity increases from approximately 0.05 to 0.3 m/s, leading to an increase in collection efficiency from about 55% to 93%. It is demonstrated that the proposed system ensures stable output voltage regulation within ±2.5–5% even under strongly nonlinear load conditions. The use of an LC output filter (C = 1–10 nF, L = 10–100 mH) reduces the voltage ripple from about 14% to 1.4–4.8% and significantly improves the transient response. In addition, adaptive adjustment of the pulse repetition frequency in the range of 10–200 kHz makes it possible to reduce energy consumption by 12–18% while simultaneously increasing the collection efficiency by 8–15%. The obtained results confirm that the proposed high-frequency power supply architecture provides a physically well-founded and energy-efficient solution for improving the environmental performance and operational stability of electrostatic precipitators. Full article