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Search Results (353)

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Keywords = high conicity

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19 pages, 2616 KiB  
Article
Structural Analysis of Joints Made of Titanium Alloy TI-6AL-4V and Stainless Steel AISI 321 with Developed Conical Contact Surfaces Obtained by Diffusion Welding
by Olena Karpovych, Ivan Karpovych, Oleksii Fedosov, Denys Zhumar, Yevhen Karakash, Miroslav Rimar, Jan Kizek and Marcel Fedak
Materials 2025, 18(15), 3596; https://doi.org/10.3390/ma18153596 (registering DOI) - 31 Jul 2025
Abstract
The object of this study is welded joints of AISI 321 and Ti-6Al-4V, obtained by diffusion welding on developed conical surfaces. The problem of creating bimetallic joints of AISI 321 and Ti-6Al-4V with developed conical contact surfaces, using diffusion welding through an intermediate [...] Read more.
The object of this study is welded joints of AISI 321 and Ti-6Al-4V, obtained by diffusion welding on developed conical surfaces. The problem of creating bimetallic joints of AISI 321 and Ti-6Al-4V with developed conical contact surfaces, using diffusion welding through an intermediate Electrolytic Tough Pitch Copper (Cu-ETP) copper layer, was solved. The joints were studied using micro-X-ray spectral analysis, microstructural analysis, and mechanical tests. High mutual diffusion of copper and titanium, along with increased concentrations of Cr and V in copper, was detected. The shear strength of the obtained welded joints is 250 MPa and 235 MPa at 30 min and 15 min, respectively, which is higher than the copper layer’s strength (180 MPa). The obtained results are explained by the dislocation diffusion mechanism in the volume of grains and beyond, due to thermal deformations during welding. Under operating conditions of internal pressure and cryogenic temperatures, the strength of the connection is ensured by the entire two-layer structure, and tightness is ensured by a vacuum-tight diffusion connection. The obtained strength of the connection (250 MPa) is sufficient under the specified operating conditions. Analysis of existing solutions in the literature review indicates that industrial application of technology for manufacturing bimetallic adapters from AISI 321 stainless steel and Ti-6Al-4V titanium alloy is limited to butt joints with small geometric dimensions. Studies of the transition zone structure and diffusion processes in bimetallic joints with developed conical contact surfaces enabled determination of factors affecting joint structure and diffusion coefficients. The obtained bimetallic adapters, made of Ti-6Al-4V titanium alloy and AISI 321 stainless steel, can be used to connect titanium high-pressure vessels with stainless steel pipelines. Full article
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18 pages, 4703 KiB  
Article
Nanoparticle-Free 3D-Printed Hydrophobic Surfaces for Ice Mitigation Applications
by Ranim Zgaren, Maryam Hosseini, Reza Jafari and Gelareh Momen
Molecules 2025, 30(15), 3185; https://doi.org/10.3390/molecules30153185 - 30 Jul 2025
Viewed by 62
Abstract
Ice accumulation on exposed surfaces presents substantial economic and safety challenges across various industries. To overcome limitations associated with traditional anti-icing methods, such as the use of nanoparticles, this study introduces a novel and facile approach for fabricating superhydrophobic and anti-icing microstructures using [...] Read more.
Ice accumulation on exposed surfaces presents substantial economic and safety challenges across various industries. To overcome limitations associated with traditional anti-icing methods, such as the use of nanoparticles, this study introduces a novel and facile approach for fabricating superhydrophobic and anti-icing microstructures using cost-effective LCD 3D printing technology. The influence of diverse pillar geometries, including square, cylindrical, hexagonal, and truncated conical forms, was analyzed to assess their effects on the hydrophobic and anti-icing/icephobic performance in terms of wettability, ice adhesion strength, and icing delay time. The role of microstructure topography was further investigated through cylindrical patterns with varying geometric parameters to identify optimal designs for enhancing hydrophobic and icephobic characteristics. Furthermore, the effectiveness of surface functionalization using a low surface energy material was evaluated. Our findings demonstrate that the synergistic combination of tailored microscale geometries and surface functionalization significantly enhances anti-icing performance with reliable repeatability, achieving ice adhesion of 13.9 and 17.9 kPa for square and cylindrical pillars, respectively. Critically, this nanoparticle-free 3D printing and low surface energy treatment method offers a scalable and efficient route for producing high-performance hydrophobic/icephobic surfaces, opening promising avenues for applications in sectors where robust anti-icing capabilities are crucial, such as renewable energy and transportation. Full article
(This article belongs to the Special Issue Micro/Nano-Materials for Anti-Icing and/or De-Icing Applications)
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24 pages, 4281 KiB  
Article
Free Vibration Characteristics of FG-CNTRC Conical–Cylindrical Combined Shells Resting on Elastic Foundations Using the Haar Wavelet Discretization Method
by Jianyu Fan, Haoran Zhang, Yongqiang Tu, Shaohui Yang, Yan Huang, Zhichang Du and Hakim Boudaoud
Polymers 2025, 17(15), 2035; https://doi.org/10.3390/polym17152035 - 25 Jul 2025
Viewed by 178
Abstract
Functionally graded carbon nanotube reinforced composites (FG-CNTRCs) are a novel breed of polymer nanocomposite, in which the nonuniform distribution of the carbon nanotube (CNT) reinforcement is adopted to maximize the macro-mechanical performance of the polymer with a lower content of CNTs. Composite conical–cylindrical [...] Read more.
Functionally graded carbon nanotube reinforced composites (FG-CNTRCs) are a novel breed of polymer nanocomposite, in which the nonuniform distribution of the carbon nanotube (CNT) reinforcement is adopted to maximize the macro-mechanical performance of the polymer with a lower content of CNTs. Composite conical–cylindrical combined shells (CCCSs) are widely utilized as loading-bearing components in various engineering applications, and a comprehensive understanding of the vibration characteristics of these shells under different external excitations and boundary conditions is crucial for engineering applications. In this study, the free vibration behaviors of FG-CNTRC CCCSs supported by an elastic foundation are examined using the Haar wavelet discretization method (HWDM). First, by means of the HWDM, the equations of motion of each shell segment, the continuity and boundary conditions are converted into a system of algebraic equations. Subsequently, the natural frequencies and modes of the CCCSs are achieved by calculating the resultant algebraic equations. The convergence and accuracy are evaluated, and the results demonstrate that the proposed method has stable convergence, high efficiency, and excellent accuracy. Furthermore, an exhaustive parametric investigation is conducted to reveal the effects of foundation stiffnesses, boundary conditions, material mechanical properties, and geometric parameters on the vibration characteristics of the FG-CNTRC CCCS. Full article
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15 pages, 7744 KiB  
Article
FEM Analysis of Superplastic-Forming Process to Manufacture a Hemispherical Shell
by Gillo Giuliano and Wilma Polini
Appl. Sci. 2025, 15(14), 8080; https://doi.org/10.3390/app15148080 - 21 Jul 2025
Viewed by 187
Abstract
Superplastic materials are characterised by extreme lightness and remarkable ductility. Instead of a punch, a gas is used to push the sheet into the die cavity, and it is precisely regulated to control the material’s strain rate. Forming a superplastic material while maintaining [...] Read more.
Superplastic materials are characterised by extreme lightness and remarkable ductility. Instead of a punch, a gas is used to push the sheet into the die cavity, and it is precisely regulated to control the material’s strain rate. Forming a superplastic material while maintaining a high strain rate sensitivity index requires the forming gas to follow a precise pressure–time loading curve. This can be excellently predicted with the aid of the finite element method (FEM). Therefore, for the superplastic material to exhibit its best formability throughout the entire process, it is necessary to control the strain rate step by step to keep the maximum strain rate within the material’s optimal superplastic range. In this work, the results of a superplastic-forming process used to create a hemispherical shell are presented. This was carried out using both a circular blank of uniform thickness and a blank with a conical cross-section. The analysis was performed using finite element modelling. Specifically, the results obtained using 3D analysis were compared with those obtained using axisymmetric analysis for conditions of axial symmetry. Using the conical cross-section blank helped achieve a more uniform thickness distribution in the produced hemispherical shell. The success of the numerical activity was validated through results from appropriate experimental work conducted on the magnesium alloy AZ31. The results show that, by employing a blank characterised by a conical section profile, the thickness distribution appears more uniform than that of a constant-thickness blank. Full article
(This article belongs to the Section Mechanical Engineering)
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12 pages, 1776 KiB  
Article
Effects of Different Moments of Inertia on Neuromuscular Performance in Elite Female Soccer Players During Hip Extension Exercise to Prevent Hamstring Asymmetries and Injuries: A Cross-Sectional Study
by Jordi Pumarola, Alesander Badiola-Zabala and Mònica Solana-Tramunt
Sports 2025, 13(7), 212; https://doi.org/10.3390/sports13070212 - 28 Jun 2025
Viewed by 353
Abstract
Background: High-intensity actions like accelerations and decelerations, often performed unilaterally, are crucial in elite female football but increase the risk of interlimb asymmetries and injury. Flywheel resistance training enhances eccentric strength, yet limited research has assessed how different inertial loads affect mechanical outputs [...] Read more.
Background: High-intensity actions like accelerations and decelerations, often performed unilaterally, are crucial in elite female football but increase the risk of interlimb asymmetries and injury. Flywheel resistance training enhances eccentric strength, yet limited research has assessed how different inertial loads affect mechanical outputs in unilateral exercises. Purpose: This study investigated how two inertial loads (0.107 kg·m2 and 0.133 kg·m2) influence power, acceleration, speed, and asymmetry during unilateral hip extensions in elite female footballers. Methods: Eighteen professional players (27 ± 4 years, 59.9 ± 6.5 kg, 168.2 ± 6.3 cm, BMI 21.2 ± 1.8) completed unilateral hip extensions on a conical flywheel under both inertia conditions. A rotary encoder measured peak/average power, acceleration, speed, and eccentric-to-concentric (E:C) ratios. Bilateral asymmetries between dominant (DL) and non-dominant (NDL) limbs were assessed. Paired t-tests and Cohen’s d were used for analysis. Results: Higher inertia reduced peak and mean acceleration and speed (p < 0.001, d > 0.8). Eccentric peak power significantly increased in the NDL (p < 0.001, d = 3.952). E:C ratios remained stable. Conclusions: Greater inertial loads reduce movement velocity but increase eccentric output in the NDL, offering potential strategies to manage neuromuscular asymmetries in elite female football players. Full article
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17 pages, 7359 KiB  
Article
Modeling of the Dynamics of Conical Separate Plates in a Wet Multi-Disc Clutch
by Qin Zhao, Biao Ma, Cenbo Xiong, Liang Yu, Bing Fu and Shufa Yan
Lubricants 2025, 13(6), 262; https://doi.org/10.3390/lubricants13060262 - 12 Jun 2025
Viewed by 357
Abstract
Wet multi-disc clutches in transmission systems suffer from the incomplete separation of the friction components, which raises the drag torque and results in power loss and heightened fuel consumption. This incomplete separation arises from the force imbalance between resistance forces, such as the [...] Read more.
Wet multi-disc clutches in transmission systems suffer from the incomplete separation of the friction components, which raises the drag torque and results in power loss and heightened fuel consumption. This incomplete separation arises from the force imbalance between resistance forces, such as the oil viscosity force, and the lack of an axial separating force. Therefore, providing an axial separating force is a potential solution to this problem. In this investigation, small-angle conical separate plates were designed which can provide the elastic restoring force during the separation process. Based on its structural properties, a model describing the clutch engagement and separation process was established. Through bench tests, the feasibility of the model was verified. The influence of the conical plate on the dynamics of the clutch was studied, including the influence of the separation gap, uniformity, and drag torque. Though the transmitted torque was reduced by 10.31% in the low-piston-pressure condition and by less than 2% in the high-piston-pressure condition, the problem of incomplete separation was successfully resolved. The results show that when applying the conical plates, the separation time was reduced by 18.78%, with a 25.31% increase in the uniformity of the gaps. Accordingly, the drag torque was reduced by 37.73%. Full article
(This article belongs to the Special Issue Tribology in Vehicles)
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15 pages, 3393 KiB  
Article
Stereotactically Guided Microsurgical Approach for Deep-Seated Eloquently Located Lesions
by Jun Thorsteinsdottir, Sebastian Siller, Biyan Nathanael Harapan, Robert Forbrig, Jörg-Christian Tonn, Tobias Greve, Stefanie Quach and Christian Schichor
J. Clin. Med. 2025, 14(12), 4175; https://doi.org/10.3390/jcm14124175 - 12 Jun 2025
Viewed by 367
Abstract
Background/Objectives: Advancements in neuronavigation and intraoperative imaging have made gross-total resection of deep-seated lesions more feasible. However, in eloquently located regions, brain shift can lead to unintentional damage of functionally critical tissue during the approach. This study analyzes the feasibility and outcomes [...] Read more.
Background/Objectives: Advancements in neuronavigation and intraoperative imaging have made gross-total resection of deep-seated lesions more feasible. However, in eloquently located regions, brain shift can lead to unintentional damage of functionally critical tissue during the approach. This study analyzes the feasibility and outcomes of a stereotactically guided microsurgical approach supported by intraoperative CT (iCT) for such lesions. Methods: Patients with deep-seated, eloquently located lesions treated between 03/2017 and 04/2023 at the Department of Neurosurgery, Ludwig-Maximilians-University (LMU) Munich, Germany, were included. Frame-based, image-guided stereotaxy was used for trajectory planning and catheter placement, verified by iCT. Microsurgical resection was conducted along the catheter trajectory using 2 mm conical blade retractors and continuous neurophysiological monitoring. Postoperative MRI assessed the extent of resection. Neurological outcomes were evaluated postoperatively, at 6 weeks, and at long-term follow-up in 12/2023. Results: A total of 12 patients were treated using the stereotactically guided microsurgical approach described in this study. In all cases, the implanted catheter precisely matched the preoperative trajectory, as confirmed by fused iCT data. Median durations were 23 min for stereotaxy and 3 h 7 min for microsurgery. Complete resection was achieved in all cases. One patient experienced transient hemiparesis and aphasia, both of which were fully resolved. All other patients showed neurological improvement or remained seizure-free at long-term follow-up. Conclusions: In selected cases, a stereotactically guided microsurgical approach with iCT enabled intraoperative localization of the target with high spatial accuracy and without immediate procedure-related complications in this limited cohort. Our findings support the feasibility of the technique; however, conclusions regarding clinical efficacy or broader applicability are limited by the small sample size and non-comparative study design. Full article
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16 pages, 4200 KiB  
Article
Insights into Localized Crystallization in the 3D-Cone Solar Evaporator for High-Salinity Desalination
by Ruolan Tang, Wanqi Chen, Bo Yang, Banghe Lv, Haile Yan, Song Li and Liang Zuo
Materials 2025, 18(11), 2610; https://doi.org/10.3390/ma18112610 - 3 Jun 2025
Viewed by 444
Abstract
Solar-driven interfacial evaporation desalination is regarded as a promising solution to address freshwater scarcity. However, salt deposition remains a significant challenge. While structural designs such as designated deposition sites can control crystallization, the mechanisms of salt precipitation at specific locations are still unclear. [...] Read more.
Solar-driven interfacial evaporation desalination is regarded as a promising solution to address freshwater scarcity. However, salt deposition remains a significant challenge. While structural designs such as designated deposition sites can control crystallization, the mechanisms of salt precipitation at specific locations are still unclear. In the present work, we designed a three-dimensional conical evaporator using low-cost cellulose paper for efficient solar-driven desalination. This innovative evaporator design achieves controlled salt crystallization by meticulously balancing the rates of salt diffusion and accumulation, thereby directing salt precipitation to a predetermined location approximately 1.4 cm above the conical base. This phenomenon arises from temperature variations across the evaporator’s three-dimensional surface, which induce differences in water surface tension and create favorable sites for salt precipitation. Such a salt management strategy allows for continuous operation for up to 8 h in high-salinity conditions (24.5 wt.%) without compromising performance. Under one sun irradiation, the evaporator demonstrates exceptional performance, with an evaporation rate of 2.54 kg·m−2·h−1 and an impressive energy conversion efficiency of 93.7%. This approach provides valuable insights into the salt precipitation mechanism, contributing to the future design of three-dimensional evaporators and innovative salt collection strategies. Full article
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12 pages, 635 KiB  
Article
Drift Versus Entropic Forces in Overdamped Diffusion Through a Widening Channel
by Michał Cieśla, Bartłomiej Dybiec, Monika Krasowska and Anna Strzelewicz
Molecules 2025, 30(11), 2316; https://doi.org/10.3390/molecules30112316 - 25 May 2025
Viewed by 378
Abstract
This study examines the diffusion of spherical particles in a conical widening channel, with a focus on the effects of deterministic drift and entropic forces. Through numerical simulations, we analyze the motion of particles from a reflecting boundary to an absorbing one. Properties [...] Read more.
This study examines the diffusion of spherical particles in a conical widening channel, with a focus on the effects of deterministic drift and entropic forces. Through numerical simulations, we analyze the motion of particles from a reflecting boundary to an absorbing one. Properties of diffusive motion are explored by inspection of mean squared displacement and mean first passage time. The results show that the diffusion type depends on the drift strength. Without the drift, entropic forces induce effective superdiffusion; however, the increasing drift strength can counterbalance entropic forces and shift the system to standard diffusion and then effective subdiffusion. The mean squared displacement exhibits bending points for high drift values, as predicted by one-dimensional theoretical considerations. The study underscores the importance of considering deterministic and entropic forces in confined geometries. Full article
(This article belongs to the Section Physical Chemistry)
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20 pages, 3955 KiB  
Article
Inversion Method Based on Temporal Convolutional Networks for Random Ice Load on Conical Offshore Platforms
by Wei Li, Ya Guo, Shuzhao Li, Yang Gao and Yan Qu
J. Mar. Sci. Eng. 2025, 13(5), 1000; https://doi.org/10.3390/jmse13051000 - 21 May 2025
Viewed by 359
Abstract
The randomness and complexity of ice loads present major challenges to the safety and stability of offshore platforms. Traditional methods for identifying ice loads often lack accuracy and adaptability under changing environmental conditions. This study proposes a novel inversion method based on Temporal [...] Read more.
The randomness and complexity of ice loads present major challenges to the safety and stability of offshore platforms. Traditional methods for identifying ice loads often lack accuracy and adaptability under changing environmental conditions. This study proposes a novel inversion method based on Temporal Convolutional Networks (TCNs), integrating finite element simulation with deep learning to effectively identify random ice loads. A random ice load model is first developed, and its dynamic characteristics are validated through finite element analysis. The TCN model is then applied to capture the time-dependent features of ice loads. To improve the model’s generalization ability, its hyperparameters are optimized using particle swarm optimization (PSO). The results show that the TCN model achieves goodness-of-fit (R2) values of 0.821 and 0.808 on the training and test sets, respectively, indicating strong predictive performance. Under different ice thickness and velocity conditions, the model achieves R2 values close to 0.99, demonstrating high robustness. This work represents the first application of TCN to ice load identification. By combining it with simulation data, we offer a high-precision, data-driven approach for dynamic load identification, enhancing the efficiency and reliability of safety assessments for conical offshore platforms. Full article
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12 pages, 2424 KiB  
Article
Growth of Two-Dimensional Edge-Rich Screwed WS2 with High Active Site Density for Accelerated Hydrogen Evolution
by Dengchao Hu, Chaocheng Sun, Yida Wang, Fade Zhao, Yubao Li, Limei Song, Cuncai Lv, Weihao Zheng and Honglai Li
Catalysts 2025, 15(5), 496; https://doi.org/10.3390/catal15050496 - 20 May 2025
Viewed by 659
Abstract
Two-dimensional transition metal dichalcogenides have attracted considerable attention in electrocatalytic hydrogen evolution due to their unique layered structures and tunable electronic properties. However, prior research has predominantly focused on the intrinsic catalytic activity of planar few-layer structures, which offer limited exposure of edge-active [...] Read more.
Two-dimensional transition metal dichalcogenides have attracted considerable attention in electrocatalytic hydrogen evolution due to their unique layered structures and tunable electronic properties. However, prior research has predominantly focused on the intrinsic catalytic activity of planar few-layer structures, which offer limited exposure of edge-active sites due to their restricted two-dimensional geometry. Moreover, van der Waals interactions between layers impose substantial barriers to electron transport, significantly hindering charge transfer efficiency. To overcome these limitations, this study presents the innovative synthesis of high-quality single-screw WS2 with a 5° dislocation angle via physical vapor deposition. Second harmonic generation measurements revealed a pronounced asymmetric polarization response, while the selected area electron diffractionand atomic force microscopy elucidated the material’s distinctive screwed dislocation configuration. In contrast to planar monolayer WS2, the conical/screw-structured WS2—formed through screw-dislocation-mediated growth—exhibits a higher density of exposed edge-active catalytic sites and enhanced electron transport capabilities. Electrochemical performance tests revealed that in an alkaline medium, the screwed WS2 nanosheets exhibited an overpotential of 310 mV at a current density of −10 mA/cm2, with a Tafel slope of 204 mV/dec. Additionally, under a current density of 18 mA/cm2, the screwed WS2 can sustain this current density for at least 30 h. These findings offer valuable insights into the design of low-cost, high-efficiency, non-precious metal catalysts for hydrogen evolution reactions. Full article
(This article belongs to the Special Issue Two-Dimensional (2D) Materials in Catalysis)
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10 pages, 260 KiB  
Article
The Impact of LDL Cholesterol, HDL Cholesterol, Triglycerides, and Vitamin D on Short-Term Implant Survival Rate: A Prospective Observational Study
by Radu Ionut Grigoraș, Roberta Gasparro, Adina Simona Coșarcă, Timea Dakó and Alina Ormenișan
J. Clin. Med. 2025, 14(10), 3531; https://doi.org/10.3390/jcm14103531 - 18 May 2025
Viewed by 645
Abstract
Background/Objectives: Dental implant success is influenced by a range of systemic and local factors. Emerging evidence suggests that metabolic markers such as lipid profiles and vitamin D levels may play a role in osseointegration and implant survival. The aim of this study [...] Read more.
Background/Objectives: Dental implant success is influenced by a range of systemic and local factors. Emerging evidence suggests that metabolic markers such as lipid profiles and vitamin D levels may play a role in osseointegration and implant survival. The aim of this study was to evaluate the influence of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, and vitamin D levels on the short-term survival rate of dental implants. Materials and Methods: A prospective observational study was conducted on patients receiving dental implants. Preoperative serum levels of LDL, HDL, triglycerides, and vitamin D were recorded. A total of 556 conical, platform-switching implants were placed in 166 patients, smokers and no smokers with mean age 48 years ± 4.7. Implant survival was evaluated from 14 to 21 days after placement, at 6- and at a 12-month follow-up. Spearman’s rank correlation was performed to assess potential correlations between the abovementioned systemic factors and implant loss. Results: Out of 556 implants, 13 (2.34%) were lost from 14 to 21 days after placement, a further two (0.35%) were lost after 6 months after surgery and a further eight (1.44%) were lost 12 months after placement. No significant correlation was found between HDL levels, cholesterol levels, triglyceride levels and implant loss. Spearman’s correlation analysis revealed a strong negative correlation between vitamin D levels and implant loss with no statistical significance. Conclusions: Within the limitations of this study, no statistically significant associations were found between lipid profile markers or vitamin D levels and early dental implant loss. Further large-scale and long-term studies are warranted to validate these findings and better understand the interplay between systemic biochemical markers and implant survival rate. Full article
(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
30 pages, 15458 KiB  
Article
Morphology Design and Precision Control of Microneedles by PμSL 3D Printing
by Baoling Jia, Tiandong Xia, Yangtao Xu and Bei Li
Polymers 2025, 17(10), 1351; https://doi.org/10.3390/polym17101351 - 15 May 2025
Cited by 1 | Viewed by 607
Abstract
Microneedles (MNs) hold significant potential for applications in transdermal drug delivery and biosensing. However, when traditional 3D printing technology is used for their manufacture, a substantial deviation in output size occurs. The effects of various parameters on the morphology of MNs produced through [...] Read more.
Microneedles (MNs) hold significant potential for applications in transdermal drug delivery and biosensing. However, when traditional 3D printing technology is used for their manufacture, a substantial deviation in output size occurs. The effects of various parameters on the morphology of MNs produced through microscale 3D printing remain unclear. This study investigated the relationship between the design and fabrication of acrylic resin MNs and their output forms via a projection microstereolithography (PµSL) technology system. Modifying the shape parameters and array configurations elucidates the causes of size deviation and proposes a control strategy. This is particularly significant for the prototyping and mold manufacturing of MNs in relevant fields. This study indicates that a printing layer thickness of 10 µm optimally balances efficiency and clinical conversion requirements. Additionally, an exposure intensity of 65 mW/cm2 achieves both a high fidelity and an appropriate base size. The printing angle significantly influences the morphology and mechanical properties of MNs. The diameter and aspect ratio of solid MNs correlate with their dimensional stability. Clinically, conical or quadrilateral MNs with defined parameters are recommended. A critical spacing (≥40 µm) and an optimal arrangement of the MN arrays were established. The specific exposure intensity and vertical printing angle of the hollow MNs ensure the precision of the micropore diameter and wall thickness. This approach offers theoretical insights and process parameters essential for high-precision, customizable MN engineering design. Full article
(This article belongs to the Special Issue 3D Printing of Polymer Composites, 2nd Edition)
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19 pages, 6096 KiB  
Article
Experimental Investigation on Water-Exit Dynamics of Slender Cylinders: Effects of Velocity, Geometry, and Material Properties
by Hualin Zheng, Hongfu Qiang, Yujie Zhu, Dudou Wang, Yuxiang Liu and Xiafei Guan
J. Mar. Sci. Eng. 2025, 13(5), 957; https://doi.org/10.3390/jmse13050957 - 15 May 2025
Viewed by 389
Abstract
This work studies the water-exit problems of slender cylinders under various conditions through experimental investigation. An experimental platform was equipped with high-speed photography. A total of 13 experimental cases with varying head shapes (conical, spherical, and truncated cone designs), length-to-diameter ratios (5:1–7:1), ejection [...] Read more.
This work studies the water-exit problems of slender cylinders under various conditions through experimental investigation. An experimental platform was equipped with high-speed photography. A total of 13 experimental cases with varying head shapes (conical, spherical, and truncated cone designs), length-to-diameter ratios (5:1–7:1), ejection velocities (7.24–17.93 m/s), and elastic moduli (227.36–279.14 MPa) were conducted to capture water-exit characteristics. The investigation identified ejection velocity as the predominant parameter governing cavity morphology and stability, with higher velocities correlating to increased cavity dimensions and reduced drag coefficients by 54%. Conical head shape resulted in superior drag reduction characteristics, forming a typical cigar-shaped cavity with clear and regular boundaries. Additionally, an increased length-to-diameter ratio substantially improved drag reduction performance by 33%. Material elastic moduli proved crucial for water-exit stability, as cylinders with lower moduli experienced severe bending deformation and even trajectory changes, while higher moduli cylinders maintained their form with minimal deformation. This study illuminates the physical mechanisms of slender body water-exit under multi-factor coupling conditions, providing experimental evidence and theoretical guidance for cross-media vehicle design and underwater equipment optimization. Full article
(This article belongs to the Special Issue Advanced Studies in Marine Mechanical and Naval Engineering)
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16 pages, 7322 KiB  
Article
Structural Study of Thermostable Ginsenoside β-Glucosidase from Caldicellulosiruptor bescii
by Jung-Min Choi
Crystals 2025, 15(5), 447; https://doi.org/10.3390/cryst15050447 - 9 May 2025
Viewed by 512
Abstract
Protopanaxadiol-type ginsenosides, the major bioactive components of Panax ginseng, exhibit diverse pharmacological activities, but suffer from low oral bioavailability due to poor water solubility and membrane permeability. Enzymatic deglycosylation has emerged as an effective strategy to enhance their therapeutic potential; however, most [...] Read more.
Protopanaxadiol-type ginsenosides, the major bioactive components of Panax ginseng, exhibit diverse pharmacological activities, but suffer from low oral bioavailability due to poor water solubility and membrane permeability. Enzymatic deglycosylation has emerged as an effective strategy to enhance their therapeutic potential; however, most glucosidases lack sufficient thermostability for industrial applications. A β-glucosidase from the thermophilic bacterium Caldicellulosiruptor bescii (CbBGL) has demonstrated efficient conversion of major ginsenosides into compound K at elevated temperatures. In this study, the high-resolution crystal structure of CbBGL was determined at 1.9 Å. Structural analysis revealed that CbBGL adopts a classical (α/β)8 TIM barrel fold and functions as a homodimer. Comparative studies with other glucosidases highlighted structural features contributing to its thermostability, including moderate B-factor distribution and a limited hydrogen bond network. Docking analyses revealed a narrow, inverted conical substrate-binding cleft, which imposes specific binding orientations and underlies the enzyme’s stepwise deglycosylation mechanism. These insights provide a structural basis for CbBGL’s thermal resilience and substrate specificity, offering a valuable platform for the rational engineering of glucosidases in ginsenoside bioconversion processes. Full article
(This article belongs to the Special Issue Crystallography of Enzymes)
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