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Search Results (4,487)

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17 pages, 1911 KB  
Editorial
Advances in (Bio)Sensors for Physiological Monitoring: A Special Issue Review
by Magnus Falk and Sergey Shleev
Sensors 2026, 26(2), 633; https://doi.org/10.3390/s26020633 (registering DOI) - 17 Jan 2026
Abstract
Physiological monitoring has become an inherently interdisciplinary field, merging advances in engineering, chemistry, biology, medicine, and data analytics to create sensors that continuously track the vital signals of the body. These developments are enabling more personalized and preventive healthcare, as wearable (bio)sensors and [...] Read more.
Physiological monitoring has become an inherently interdisciplinary field, merging advances in engineering, chemistry, biology, medicine, and data analytics to create sensors that continuously track the vital signals of the body. These developments are enabling more personalized and preventive healthcare, as wearable (bio)sensors and intelligent algorithms can detect subtle physiological changes in real-time. In the Special Issue ‘Advances in (Bio)Sensors for Physiological Monitoring’, researchers from diverse domains contributed 18 papers showcasing cutting-edge sensor technologies and applications for health and performance monitoring. In this review, we summarize these contributions by grouping them into logical themes based on their focus: (1) cardiovascular and autonomic monitoring, (2) glucose and metabolic monitoring, (3) wearable sensors for movement and musculoskeletal health, (4) neurophysiological monitoring and brain–computer interfaces, and (5) innovations in sensor technology and methods. This thematic organization highlights the breadth of the research, spanning from fundamental sensor hardware to data-driven analytics, and underscores how modern (bio)sensors are breaking traditional boundaries in healthcare. Full article
(This article belongs to the Special Issue (Bio)sensors for Physiological Monitoring)
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21 pages, 1613 KB  
Article
Dual-Functional Polyurethane Sponge-Based Pressure Sensors Incorporating BZT/BTO, Polypyrrole, and Carbon Nanotubes with Energy Generation Capability
by Nurhan Onar Camlibel and Baljinder K. Kandola
Polymers 2026, 18(2), 241; https://doi.org/10.3390/polym18020241 - 16 Jan 2026
Viewed by 28
Abstract
Flexible and wearable pressure sensors are essential for monitoring of human motion and are distinguished by their increased sensitivity and outstanding mechanical robustness. In this study, we systematically engineered a flexible and wearable pressure sensor with a multilayer conductive architecture, arranging a sponge [...] Read more.
Flexible and wearable pressure sensors are essential for monitoring of human motion and are distinguished by their increased sensitivity and outstanding mechanical robustness. In this study, we systematically engineered a flexible and wearable pressure sensor with a multilayer conductive architecture, arranging a sponge substrate coated in a consecutive manner with a barium zirconium titanate thin film, followed by polypyrrole, multiwalled carbon nanotubes, and eventually polydimethylsiloxane. The foundation of additional conductive pathways is enabled via the utilization of a porous framework and the hierarchical arrangement, causing the achievement of an excellent sensitivity of 9.71 kPa–1 (0–9 kPa), a rapid 40 ms response time, and a fast 60 ms recovery period, combined with a particularly low detection limit (125 Pa) and an extended pressure range from 0 to 225 kPa. Furthermore, the integration of a rough and porous barium zirconium titanate/barium titanate thin film is expected to deliver a voltage output (1.25 V) through piezoelectric working mechanisms. This study possesses the potential to provide an innovative architecture design for advancing the development of future electronic devices for health and sports monitoring. Full article
(This article belongs to the Special Issue Advanced Polymers in Sensor Applications)
23 pages, 16288 KB  
Article
End-Edge-Cloud Collaborative Monitoring System with an Intelligent Multi-Parameter Sensor for Impact Anomaly Detection in GIL Pipelines
by Qi Li, Kun Zeng, Yaojun Zhou, Xiongyao Xie and Genji Tang
Sensors 2026, 26(2), 606; https://doi.org/10.3390/s26020606 - 16 Jan 2026
Viewed by 45
Abstract
Gas-insulated transmission lines (GILs) are increasingly deployed in dense urban power networks, where complex construction activities may introduce external mechanical impacts and pose risks to pipeline structural integrity. However, existing GIL monitoring approaches mainly emphasize electrical and gas-state parameters, while lightweight solutions capable [...] Read more.
Gas-insulated transmission lines (GILs) are increasingly deployed in dense urban power networks, where complex construction activities may introduce external mechanical impacts and pose risks to pipeline structural integrity. However, existing GIL monitoring approaches mainly emphasize electrical and gas-state parameters, while lightweight solutions capable of rapidly detecting and localizing impact-induced structural anomalies remain limited. To address this gap, this paper proposes an intelligent end-edge-cloud monitoring system for impact anomaly detection in GIL pipelines. Numerical simulations are first conducted to analyze the dynamic response characteristics of the pipeline under impacts of varying magnitudes, orientations, and locations, revealing the relationship between impact scenarios and vibration mode evolution. An end-tier multi-parameter intelligent sensor is then developed, integrating triaxial acceleration and angular velocity measurement with embedded lightweight computing. Laboratory impact experiments are performed to acquire sensor data, which are used to train and validate a multi-class extreme gradient boosting (XGBoost) model deployed at the edge tier for accurate impact-location identification. Results show that, even with a single sensor positioned at the pipeline midpoint, fusing acceleration and angular velocity features enables reliable discrimination of impact regions. Finally, a lightweight cloud platform is implemented for visualizing structural responses and environmental parameters with downsampled edge-side data. The proposed system achieves rapid sensor-level anomaly detection, precise edge-level localization, and unified cloud-level monitoring, offering a low-cost and easily deployable solution for GIL structural health assessment. Full article
(This article belongs to the Section Industrial Sensors)
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27 pages, 2521 KB  
Article
IoTToe: Monitoring Foot Angle Variability for Health Management and Safety
by Ata Jahangir Moshayedi, Zeashan Khan, Zhonghua Wang and Mehran Emadi Andani
Math. Comput. Appl. 2026, 31(1), 13; https://doi.org/10.3390/mca31010013 - 16 Jan 2026
Viewed by 38
Abstract
Toe-in (inward) and toe-out (outward) foot alignments significantly affect gait, posture, and joint stress, causing issues like abnormal gait, joint strain, and foot conditions such as plantar fasciitis and high arches. Addressing these alignments is crucial for improving mobility and comfort. This study [...] Read more.
Toe-in (inward) and toe-out (outward) foot alignments significantly affect gait, posture, and joint stress, causing issues like abnormal gait, joint strain, and foot conditions such as plantar fasciitis and high arches. Addressing these alignments is crucial for improving mobility and comfort. This study introduces IoTToe, a wearable IoT device designed to detect and monitor gait patterns by using six ADXL345 sensors positioned on the foot, allowing healthcare providers to remotely monitor alignment via a webpage, reducing the need for physical tests. Tested on 45 participants aged 20–25 years with diverse BMIs, IoTToe proved suitable for both children and adults, supporting therapy and diagnostics. Statistical tests, including ICC, DFA, and ANOVA, confirmed the device’s effectiveness in detecting gait and postural control differences between legs. Gait variability results indicated that left leg showed more adaptability (DFA close to 0.5), compared to the right leg which was found more consistent (DFA close to 1). Postural control showed stable and agile standing with values between 0.5 and 1. Sensor combinations revealed that removing sensor B (on the gastrocnemius muscle) did not affect data quality. Moreover, taller individuals displayed smaller ankle angle changes, highlighting challenges in balance and upper body stability. IoTToe offers accurate data collection, reliability, portability, and significant potential for gait monitoring and injury prevention. Future studies would expand participation, especially among women and those with alignment issues, to enhance the system’s applicability for foot health management, safety and rehabilitation, further supporting telemetric applications in healthcare. Full article
(This article belongs to the Special Issue Advances in Computational and Applied Mechanics (SACAM))
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8 pages, 4250 KB  
Communication
A Dual-Mode Flexible Sensor with Capacitive–Resistive Hybrid Response for Bolt Loosening Monitoring
by Yan Ping, Kechen Li, Chao Yuan, Ding Guo and Yuanyuan Yang
Sensors 2026, 26(2), 578; https://doi.org/10.3390/s26020578 - 15 Jan 2026
Viewed by 84
Abstract
The structural health monitoring of bolted connections is important for ensuring the safety and reliability of engineering systems, yet conventional sensing technologies struggle to balance detection range and sensitivity. This study presents a flexible sensor with a hybrid capacitive–resistive sensing mechanism, designed to [...] Read more.
The structural health monitoring of bolted connections is important for ensuring the safety and reliability of engineering systems, yet conventional sensing technologies struggle to balance detection range and sensitivity. This study presents a flexible sensor with a hybrid capacitive–resistive sensing mechanism, designed to overcome the limitations of single-mode sensors. By integrating a hierarchically structured composite layer with tailored material properties, the sensor achieves a seamless transition between sensing modes across different pressure ranges. It exhibits high sensitivity in both low-pressure and high-pressure regions, enabling the reliable detection of preload variations in bolted connections. Experimental validation confirms its cyclic durability and rapid response to mechanical changes, demonstrating good potential for real-time monitoring in aerospace and industrial systems. Full article
(This article belongs to the Special Issue Flexible Sensing in Robotics, Healthcare, and Beyond)
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6 pages, 159 KB  
Editorial
Wearable Sensors for Human Health Monitoring and Analysis
by Alessandro Scano, Rebecca Re, Paolo Perego and Alfonso Mastropietro
Sensors 2026, 26(2), 575; https://doi.org/10.3390/s26020575 - 15 Jan 2026
Viewed by 97
Abstract
Many fields of research have recently made significant progress with the use of wearable sensors for the evaluation, monitoring, and analysis of health in several contexts, including healthcare [...] Full article
(This article belongs to the Special Issue Wearable Sensors for Human Health Monitoring and Analysis)
6 pages, 374 KB  
Proceeding Paper
Rethinking Rural Resilience: Bridging Ecology and Technology for Low-Carbon, Biodiverse Rural Economies Within the Context of European Green Deal
by Aphrodite Lioliou and Stavroula Kyritsi
Proceedings 2026, 134(1), 46; https://doi.org/10.3390/proceedings2026134046 - 14 Jan 2026
Viewed by 83
Abstract
This paper explores the intersection of digital technologies, sustainable agriculture, and biodiversity conservation within the framework of the European Green Deal. The study investigates how intelligent agricultural practices—enabled by digital tools such as sensors, AI, and IoT—can enhance soil health and conserve agrobiodiversity. [...] Read more.
This paper explores the intersection of digital technologies, sustainable agriculture, and biodiversity conservation within the framework of the European Green Deal. The study investigates how intelligent agricultural practices—enabled by digital tools such as sensors, AI, and IoT—can enhance soil health and conserve agrobiodiversity. A systematic literature review was conducted to map out current research trajectories, identify the taxonomic focus areas in biodiversity monitoring, and assess the integration of digital tools. Results show a significant upward trend in publications linking digitalization and sustainability in agriculture. Findings highlight that pollinators and soil biota dominate monitoring focus, while technologies like remote sensing and AI show increasing adoption. The study concludes that intelligent agriculture offers a path toward ecological and economic resilience in rural landscapes, aligning with the EU’s green transition agenda. Full article
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22 pages, 3418 KB  
Article
LGSTA-GNN: A Local-Global Spatiotemporal Attention Graph Neural Network for Bridge Structural Damage Detection
by Die Liu, Jianxi Yang, Jianming Li, Jingyuan Shen, Youjia Zhang, Lihua Chen and Lei Zhou
Buildings 2026, 16(2), 348; https://doi.org/10.3390/buildings16020348 - 14 Jan 2026
Viewed by 189
Abstract
Accurate detection of structural damage is essential for ensuring the safety and reliability of bridges. However, traditional vibration-based approaches often struggle to capture rich feature representations and adequately model spatial dependencies among sensors. This study proposes a novel bridge damage detection framework, LGSTA-GNN, [...] Read more.
Accurate detection of structural damage is essential for ensuring the safety and reliability of bridges. However, traditional vibration-based approaches often struggle to capture rich feature representations and adequately model spatial dependencies among sensors. This study proposes a novel bridge damage detection framework, LGSTA-GNN, which integrates local–global spatiotemporal learning with graph neural networks. The framework first extracts multi-scale temporal–frequency features using a multi-scale feature extraction module. A local graph feature extraction module then models intrinsic spatial relationships through graph convolutions, while a global graph attention module adaptively captures inter-sensor dependencies by emphasizing structurally informative nodes. A benchmark dataset generated from a scaled bridge model under progressive damage states is used to evaluate the proposed method. Extensive experiments demonstrate that LGSTA-GNN outperforms multiple graph neural network variants and conventional deep learning techniques, achieving superior accuracy, precision, recall, and F1-score. The confusion matrix and t-SNE visualization further verify its enhanced discriminative capability and robustness. Ablation studies confirm the contribution of each module, highlighting the effectiveness of global attention in identifying subtle structural deterioration. Overall, LGSTA-GNN provides an effective and interpretable solution for intelligent bridge damage detection, with strong potential for practical structural health monitoring and real-time safety assessment. Full article
(This article belongs to the Special Issue Research in Structural Control and Monitoring)
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28 pages, 1779 KB  
Review
Two-Dimensional Carbon-Based Electrochemical Sensors for Pesticide Detection: Recent Advances and Environmental Monitoring Applications
by K. Imran, Al Amin, Gajapaneni Venkata Prasad, Y. Veera Manohara Reddy, Lestari Intan Gita, Jeyaraj Wilson and Tae Hyun Kim
Biosensors 2026, 16(1), 62; https://doi.org/10.3390/bios16010062 - 14 Jan 2026
Viewed by 163
Abstract
Pesticides have been widely applied in agricultural practices over the past decades to protect crops from pests and other harmful organisms. However, their extensive use results in the contamination of soil, water, and agricultural products, posing significant risks to human and environmental health. [...] Read more.
Pesticides have been widely applied in agricultural practices over the past decades to protect crops from pests and other harmful organisms. However, their extensive use results in the contamination of soil, water, and agricultural products, posing significant risks to human and environmental health. Exposure to pesticides can lead to skin irritation, respiratory disorders, and various chronic health problems. Moreover, pesticides frequently enter surface water bodies such as rivers and lakes through agricultural runoff and leaching processes. Therefore, developing effective analytical methods for the rapid and sensitive detection of pesticides in food and water is of great importance. Electrochemical sensing techniques have shown remarkable progress in pesticide analysis due to their high sensitivity, simplicity, and potential for on-site monitoring. Two-dimensional (2D) carbon nanomaterials have emerged as efficient electrocatalysts for the precise and selective detection of pesticides, owing to their large surface area, excellent electrical conductivity, and unique structural features. In this review, we summarize recent advancements in the electrochemical detection of pesticides using 2D carbon-based materials. Comprehensive information on electrode fabrication, sensing mechanisms, analytical performance—including sensing range and limit of detection—and the versatility of 2D carbon composites for pesticide detection is provided. Challenges and future perspectives in developing highly sensitive and selective electrochemical sensing platforms are also discussed, highlighting their potential for simultaneous pesticide monitoring in food and environmental samples. Carbon-based electrochemical sensors have been the subject of many investigations, but their practical application in actual environmental and food samples is still restricted because of matrix effects, operational instability, and repeatability issues. In order to close the gap between laboratory research and real-world applications, this review critically examines sensor performance in real-sample conditions and offers innovative approaches for in situ pesticide monitoring. Full article
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45 pages, 9328 KB  
Review
Advancements in Machine Learning-Assisted Flexible Electronics: Technologies, Applications, and Future Prospects
by Hao Su, Hongcun Wang, Dandan Sang, Santosh Kumar, Dao Xiao, Jing Sun and Qinglin Wang
Biosensors 2026, 16(1), 58; https://doi.org/10.3390/bios16010058 - 13 Jan 2026
Viewed by 97
Abstract
The integration of flexible electronics and machine learning (ML) algorithms has become a revolutionary force driving the field of intelligent sensing, giving rise to a new generation of intelligent devices and systems. This article provides a systematic review of core technologies and practical [...] Read more.
The integration of flexible electronics and machine learning (ML) algorithms has become a revolutionary force driving the field of intelligent sensing, giving rise to a new generation of intelligent devices and systems. This article provides a systematic review of core technologies and practical applications of ML in flexible electronics. It focuses on analyzing the theoretical frameworks of algorithms such as the Long Short-Term Memory Network (LSTM), Convolutional Neural Network (CNN), and Reinforcement Learning (RL) in the intelligent processing of sensor signals (IPSS), multimodal feature extraction (MFE), process defect and anomaly detection (PDAD), and data compression and edge computing (DCEC). This study explores the performance advantages of these technologies in optimizing signal analysis accuracy, compensating for interference in high-noise environments, optimizing manufacturing process parameters, etc., and empirically analyzes their potential applications in wearable health monitoring systems, intelligent control of soft robots, performance optimization of self-powered devices, and intelligent perception of epidermal electronic systems. Full article
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42 pages, 4878 KB  
Review
Carbon Nanotubes and Graphene in Polymer Composites for Strain Sensors: Synthesis, Functionalization, and Application
by Aleksei V. Shchegolkov, Alexandr V. Shchegolkov and Vladimir V. Kaminskii
J. Compos. Sci. 2026, 10(1), 43; https://doi.org/10.3390/jcs10010043 - 13 Jan 2026
Viewed by 177
Abstract
This review provides a comprehensive analysis of modern strategies for the synthesis, functionalization, and application of carbon nanotubes (CNTs) and graphene for the development of high-performance polymer composites in the field of strain sensing. The paper systematically organizes key synthesis methods for CNTs [...] Read more.
This review provides a comprehensive analysis of modern strategies for the synthesis, functionalization, and application of carbon nanotubes (CNTs) and graphene for the development of high-performance polymer composites in the field of strain sensing. The paper systematically organizes key synthesis methods for CNTs and graphene (chemical vapor deposition (CVD), such as arc discharge, laser ablation, microwave synthesis, and flame synthesis, as well as approaches to their chemical and physical modification aimed at enhancing dispersion within polymer matrices and strengthening interfacial adhesion. A detailed examination is presented on the structural features of the nanofillers, such as the CNT aspect ratio, graphene oxide modification, and the formation of hybrid 3D networks and processing techniques, which enable the targeted control of the nanocomposite’s electrical conductivity, mechanical strength, and flexibility. Central focus is placed on the fundamental mechanisms of the piezoresistive response, analyzing the role of percolation thresholds, quantum tunneling effects, and the reconfiguration of conductive networks under mechanical load. The review summarizes the latest advancements in flexible and stretchable sensors capable of detecting both micro- and macro-strains for structural health monitoring, highlighting the achieved improvements in sensitivity, operational range, and durability of the composites. Ultimately, this analysis clarifies the interrelationship between nanofiller structure (CNTs and graphene), processing conditions, and sensor functionality, highlighting key avenues for future innovation in smart materials and wearable devices. Full article
(This article belongs to the Section Nanocomposites)
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34 pages, 4355 KB  
Review
Thin-Film Sensors for Industry 4.0: Photonic, Functional, and Hybrid Photonic-Functional Approaches to Industrial Monitoring
by Muhammad A. Butt
Coatings 2026, 16(1), 93; https://doi.org/10.3390/coatings16010093 - 12 Jan 2026
Viewed by 201
Abstract
The transition toward Industry 4.0 requires advanced sensing platforms capable of delivering real-time, high-fidelity data under extreme industrial conditions. Thin-film sensors, leveraging both photonic and functional approaches, are emerging as key enablers of this transformation. By exploiting optical phenomena such as Fabry–Pérot interference, [...] Read more.
The transition toward Industry 4.0 requires advanced sensing platforms capable of delivering real-time, high-fidelity data under extreme industrial conditions. Thin-film sensors, leveraging both photonic and functional approaches, are emerging as key enablers of this transformation. By exploiting optical phenomena such as Fabry–Pérot interference, guided-mode resonance, plasmonics, and photonic crystal effects, thin-film photonic devices provide highly sensitive, electromagnetic interference-immune, and remotely interrogated solutions for monitoring temperature, strain, and chemical environments. Complementarily, functional thin films including oxide-based chemiresistors, nanoparticle coatings, and flexible electronic skins extend sensing capabilities to diverse industrial contexts, from hazardous gas detection to structural health monitoring. This review surveys the fundamental optical principles, material platforms, and deposition strategies that underpin thin-film sensors, emphasizing advances in nanostructured oxides, 2D materials, hybrid perovskites, and additive manufacturing methods. Application-focused sections highlight their deployment in temperature and stress monitoring, chemical leakage detection, and industrial safety. Integration into Internet of Things (IoT) networks, cyber-physical systems, and photonic integrated circuits is examined, alongside challenges related to durability, reproducibility, and packaging. Future directions point to AI-driven signal processing, flexible and printable architectures, and autonomous self-calibration. Together, these developments position thin-film sensors as foundational technologies for intelligent, resilient, and adaptive manufacturing in Industry 4.0. Full article
(This article belongs to the Section Thin Films)
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28 pages, 4481 KB  
Article
Smart Steering Wheel Prototype for In-Vehicle Vital Sign Monitoring
by Branko Babusiak, Maros Smondrk, Lubomir Trpis, Tomas Gajdosik, Rudolf Madaj and Igor Gajdac
Sensors 2026, 26(2), 477; https://doi.org/10.3390/s26020477 - 11 Jan 2026
Viewed by 334
Abstract
Drowsy driving and sudden medical emergencies are major contributors to traffic accidents, necessitating continuous, non-intrusive driver monitoring. Since current technologies often struggle to balance accuracy with practicality, this study presents the design, fabrication, and validation of a smart steering wheel prototype. The device [...] Read more.
Drowsy driving and sudden medical emergencies are major contributors to traffic accidents, necessitating continuous, non-intrusive driver monitoring. Since current technologies often struggle to balance accuracy with practicality, this study presents the design, fabrication, and validation of a smart steering wheel prototype. The device integrates dry-contact electrocardiogram (ECG), photoplethysmography (PPG), and inertial sensors to facilitate multimodal physiological monitoring. The system underwent a two-stage evaluation involving a single participant: laboratory validation benchmarking acquired signals against medical-grade equipment, followed by real-world testing in a custom electric research vehicle to assess performance under dynamic conditions. Laboratory results demonstrated that the prototype captured high-quality signals suitable for reliable heart rate variability analysis. Furthermore, on-road evaluation confirmed the system’s operational functionality; despite increased noise from motion artifacts, the ECG signal remained sufficiently robust for continuous R-peak detection. These findings confirm that the multimodal smart steering wheel is a feasible solution for unobtrusive driver monitoring. This integrated platform provides a solid foundation for developing sophisticated machine-learning algorithms to enhance road safety by predicting fatigue and detecting adverse health events. Full article
(This article belongs to the Section Electronic Sensors)
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19 pages, 653 KB  
Perspective
Assistive Intelligence: A Framework for AI-Powered Technologies Across the Dementia Continuum
by Bijoyaa Mohapatra and Reza Ghaiumy Anaraky
J. Ageing Longev. 2026, 6(1), 8; https://doi.org/10.3390/jal6010008 - 10 Jan 2026
Viewed by 216
Abstract
Dementia is a progressive condition that affects cognition, communication, mobility, and independence, posing growing challenges for individuals, caregivers, and healthcare systems. While traditional care models often focus on symptom management in later stages, emerging artificial intelligence (AI) technologies offer new opportunities for proactive [...] Read more.
Dementia is a progressive condition that affects cognition, communication, mobility, and independence, posing growing challenges for individuals, caregivers, and healthcare systems. While traditional care models often focus on symptom management in later stages, emerging artificial intelligence (AI) technologies offer new opportunities for proactive and personalized support across the dementia trajectory. This concept paper presents the Assistive Intelligence framework, which aligns AI-powered interventions with each stage of dementia: preclinical, mild, moderate, and severe. These are mapped across four core domains: cognition, mental health, physical health and independence, and caregiver support. We illustrate how AI applications, including generative AI, natural language processing, and sensor-based monitoring, can enable early detection, cognitive stimulation, emotional support, safe daily functioning, and reduced caregiver burden. The paper also addresses critical implementation considerations such as interoperability, usability, and scalability, and examines ethical challenges related to privacy, fairness, and explainability. We propose a research and innovation roadmap to guide the responsible development, validation, and dissemination of AI technologies that are adaptive, inclusive, and centered on individual well-being. By advancing this framework, we aim to promote equitable and person-centered dementia care that evolves with individuals’ changing needs. Full article
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29 pages, 3694 KB  
Review
Innovative Bio(Nano)Sensor Designs for Cortisol Stress Hormone Detection: A Continuous Progress
by Alexandra Nicolae-Maranciuc, Dan Chicea and Andreea Campu
Processes 2026, 14(2), 239; https://doi.org/10.3390/pr14020239 - 9 Jan 2026
Viewed by 233
Abstract
Nowadays, the population is subject to a lot of stress, being one of society’s most encountered problems affecting people all over the world. Being under a lot of stress for prolonged periods of time impacts the physical and mental health of individuals with [...] Read more.
Nowadays, the population is subject to a lot of stress, being one of society’s most encountered problems affecting people all over the world. Being under a lot of stress for prolonged periods of time impacts the physical and mental health of individuals with effects on society as an economic burden. Cortisol is one of the main indicators of stress. Long-term exposure to this stress hormone can lead to severe medical conditions such as heart disease, lung issues, obesity, anxiety, or depression. In this context, the current review aims to provide a comprehensive overview of the most recent advances made in the development of versatile and efficient cortisol devices and biosensors capable of monitoring the cortisol levels in biofluids. Lately, both non-plasmonic (polymer-based sensors, optical sensors, electrochemical sensors) and plasmonic sensors (mono- and multiple-metallic nanoparticles-based sensors) have shown great results in cortisol detection. The work focuses on the advantages, remaining restrictions, and limitations in the field of cortisol biosensors from solution-based immunosensors to wearable and Lab-on-Skin monitoring devices, providing a better understanding of the fulfilled requirements and persisting challenges in the accurate detection and monitoring of the cortisol stress hormone. Full article
(This article belongs to the Section Materials Processes)
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