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Search Results (1,329)

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22 pages, 4895 KB  
Article
Carbon Convenience Yields and Probability Density Forecasts for Carbon Returns
by Meng Han, Jia You and Min Lin
Mathematics 2026, 14(2), 315; https://doi.org/10.3390/math14020315 - 16 Jan 2026
Viewed by 25
Abstract
We explore the role of carbon convenience yields in forecasting the probability density of carbon returns. While theory suggests that convenience yields contain forward-looking information, their predictive content for carbon returns—especially in a density forecasting framework—remains underexplored. We propose a probability density forecasting [...] Read more.
We explore the role of carbon convenience yields in forecasting the probability density of carbon returns. While theory suggests that convenience yields contain forward-looking information, their predictive content for carbon returns—especially in a density forecasting framework—remains underexplored. We propose a probability density forecasting approach that combines a mixed data sampling (MIDAS) regression with a non-parametric bootstrap and kernel density estimation. Using data from the European carbon market, we find that convenience yields significantly predict carbon returns. It takes approximately 19 days for a disturbance in carbon convenience yields to affect carbon returns, with the impact persisting for around 27 days. Moreover, our approach outperforms existing benchmark models in predicting the probability density of carbon returns, showing superior predictive accuracy and robustness. Full article
(This article belongs to the Special Issue Mathematical Problems in Financial Fluctuations and Forecasting)
32 pages, 8754 KB  
Review
Plasmonics Meets Metasurfaces: A Vision for Next Generation Planar Optical Systems
by Muhammad A. Butt
Micromachines 2026, 17(1), 119; https://doi.org/10.3390/mi17010119 - 16 Jan 2026
Viewed by 161
Abstract
Plasmonics and metasurfaces (MSs) have emerged as two of the most influential platforms for manipulating light at the nanoscale, each offering complementary strengths that challenge the limits of conventional optical design. Plasmonics enables extreme subwavelength field confinement, ultrafast light–matter interaction, and strong optical [...] Read more.
Plasmonics and metasurfaces (MSs) have emerged as two of the most influential platforms for manipulating light at the nanoscale, each offering complementary strengths that challenge the limits of conventional optical design. Plasmonics enables extreme subwavelength field confinement, ultrafast light–matter interaction, and strong optical nonlinearities, while MSs provide versatile and compact control over phase, amplitude, polarization, and dispersion through planar, nanostructured interfaces. Recent advances in materials, nanofabrication, and device engineering are increasingly enabling these technologies to be combined within unified planar and hybrid optical platforms. This review surveys the physical principles, material strategies, and device architectures that underpin plasmonic, MS, and hybrid plasmonic–dielectric systems, with an emphasis on interface-mediated optical functionality rather than long-range guided-wave propagation. Key developments in modulators, detectors, nanolasers, metalenses, beam steering devices, and programmable optical surfaces are discussed, highlighting how hybrid designs can leverage strong field localization alongside low-loss wavefront control. System-level challenges including optical loss, thermal management, dispersion engineering, and large-area fabrication are critically examined. Looking forward, plasmonic and MS technologies are poised to define a new generation of flat, multifunctional, and programmable optical systems. Applications spanning imaging, sensing, communications, augmented and virtual reality, and optical information processing illustrate the transformative potential of these platforms. By consolidating recent progress and outlining future directions, this review provides a coherent perspective on how plasmonics and MSs are reshaping the design space of next-generation planar optical hardware. Full article
(This article belongs to the Special Issue Photonic and Optoelectronic Devices and Systems, 4th Edition)
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40 pages, 1968 KB  
Article
Large Model in Low-Altitude Economy: Applications and Challenges
by Jinpeng Hu, Wei Wang, Yuxiao Liu and Jing Zhang
Big Data Cogn. Comput. 2026, 10(1), 33; https://doi.org/10.3390/bdcc10010033 - 16 Jan 2026
Viewed by 238
Abstract
The integration of large models and multimodal foundation models into the low-altitude economy is driving a transformative shift, enabling intelligent, autonomous, and efficient operations for low-altitude vehicles (LAVs). This article provides a comprehensive analysis of the role these large models play within the [...] Read more.
The integration of large models and multimodal foundation models into the low-altitude economy is driving a transformative shift, enabling intelligent, autonomous, and efficient operations for low-altitude vehicles (LAVs). This article provides a comprehensive analysis of the role these large models play within the smart integrated lower airspace system (SILAS), focusing on their applications across the four fundamental networks: facility, information, air route, and service. Our analysis yields several key findings, which pave the way for enhancing the application of large models in the low-altitude economy. By leveraging advanced capabilities in perception, reasoning, and interaction, large models are demonstrated to enhance critical functions such as high-precision remote sensing interpretation, robust meteorological forecasting, reliable visual localization, intelligent path planning, and collaborative multi-agent decision-making. Furthermore, we find that the integration of these models with key enabling technologies, including edge computing, sixth-generation (6G) communication networks, and integrated sensing and communication (ISAC), effectively addresses challenges related to real-time processing, resource constraints, and dynamic operational environments. Significant challenges, including sustainable operation under severe resource limitations, data security, network resilience, and system interoperability, are examined alongside potential solutions. Based on our survey, we discuss future research directions, such as the development of specialized low-altitude models, high-efficiency deployment paradigms, advanced multimodal fusion, and the establishment of trustworthy distributed intelligence frameworks. This survey offers a forward-looking perspective on this rapidly evolving field and underscores the pivotal role of large models in unlocking the full potential of the next-generation low-altitude economy. Full article
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21 pages, 378 KB  
Article
Can Climate Transition Risks Enhance Enterprise Green Innovation? An Analysis Employing a Dual Regulatory Mechanism
by Liping Cao and Fengqi Zhou
Climate 2026, 14(1), 18; https://doi.org/10.3390/cli14010018 - 15 Jan 2026
Viewed by 100
Abstract
In the context of the global pursuit of the ‘carbon neutrality’ objective, Chinese enterprises are proactively advancing green development and low-carbon transformation. Among these efforts, climate transition risks have emerged as a crucial factor affecting strategic enterprise decisions and long-term competitiveness. This study [...] Read more.
In the context of the global pursuit of the ‘carbon neutrality’ objective, Chinese enterprises are proactively advancing green development and low-carbon transformation. Among these efforts, climate transition risks have emerged as a crucial factor affecting strategic enterprise decisions and long-term competitiveness. This study utilizes a sample comprising Chinese A-share listed enterprises over the period from 2012 to 2024 to construct an enterprise climate transition risk index using text analysis methods. It empirically investigates this index’s impact on enterprise green innovation by adopting panel data analysis method to construct a fixed effects model and further examines the moderating roles of institutional investors’ shareholding and enterprise environmental uncertainties in response to climate transition risks. The research findings indicate the following: First, climate transition risks significantly enhance enterprise green innovation. The validity of this conclusion persists following a series of robustness and endogeneity tests, including replacing the explained variable, lagging the explanatory variable, controlling for city-level fixed effects, and applying instrumental variable methods. Second, both institutional investors’ shareholding and enterprise environmental uncertainties exert a significant positive regulatory effect on the relationship between climate transition risk and green innovation, indicating that external monitoring and heightened risk perception jointly enhance enterprises’ responsiveness in driving green innovation. Thirdly, heterogeneity analysis indicates that the positive impact of climate transition risks on green innovation is notably amplified within non-state-owned enterprises and manufacturing enterprises. By examining the dual regulatory mechanisms of ‘external monitoring’ and ‘risk perception’, this study broadens the study framework on the relationship between climate risks and enterprise green innovation, offering new empirical evidence supporting the applicability of the ‘Porter Hypothesis’ within the context of climate-related challenges. Furthermore, it provides valuable implications for policymakers in refining climate information disclosure policies and assists enterprises in developing forward-looking green innovation strategies. Full article
(This article belongs to the Special Issue Climate Change Adaptation Costs and Finance)
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34 pages, 12645 KB  
Article
Multimodal Intelligent Perception at an Intersection: Pedestrian and Vehicle Flow Dynamics Using a Pipeline-Based Traffic Analysis System
by Bao Rong Chang, Hsiu-Fen Tsai and Chen-Chia Chen
Electronics 2026, 15(2), 353; https://doi.org/10.3390/electronics15020353 - 13 Jan 2026
Viewed by 195
Abstract
Traditional automated monitoring systems adopted for Intersection Traffic Control still face challenges, including high costs, maintenance difficulties, insufficient coverage, poor multimodal data integration, and limited traffic information analysis. To address these issues, the study proposes a sovereign AI-driven Smart Transportation governance approach, developing [...] Read more.
Traditional automated monitoring systems adopted for Intersection Traffic Control still face challenges, including high costs, maintenance difficulties, insufficient coverage, poor multimodal data integration, and limited traffic information analysis. To address these issues, the study proposes a sovereign AI-driven Smart Transportation governance approach, developing a mobile AI solution equipped with multimodal perception, task decomposition, memory, reasoning, and multi-agent collaboration capabilities. The proposed system integrates computer vision, multi-object tracking, natural language processing, Retrieval-Augmented Generation (RAG), and Large Language Models (LLMs) to construct a Pipeline-based Traffic Analysis System (PTAS). The PTAS can produce real-time statistics on pedestrian and vehicle flows at intersections, incorporating potential risk factors such as traffic accidents, construction activities, and weather conditions for multimodal data fusion analysis, thereby providing forward-looking traffic insights. Experimental results demonstrate that the enhanced DuCRG-YOLOv11n pre-trained model, equipped with our proposed new activation function βsilu, can accurately identify various vehicle types in object detection, achieving a frame rate of 68.25 FPS and a precision of 91.4%. Combined with ByteTrack, it can track over 90% of vehicles in medium- to low-density traffic scenarios, obtaining a 0.719 in MOTA and a 0.08735 in MOTP. In traffic flow analysis, the RAG of Vertex AI, combined with Claude Sonnet 4 LLMs, provides a more comprehensive view, precisely interpreting the causes of peak-hour congestion and effectively compensating for missing data through contextual explanations. The proposed method can enhance the efficiency of urban traffic regulation and optimizes decision support in intelligent transportation systems. Full article
(This article belongs to the Special Issue Interactive Design for Autonomous Driving Vehicles)
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21 pages, 2930 KB  
Article
Robust Model Predictive Control with a Dynamic Look-Ahead Re-Entry Strategy for Trajectory Tracking of Differential-Drive Robots
by Diego Guffanti, Moisés Filiberto Mora Murillo, Santiago Bustamante Sanchez, Javier Oswaldo Obregón Gutiérrez, Marco Alejandro Hinojosa, Alberto Brunete, Miguel Hernando and David Álvarez
Sensors 2026, 26(2), 520; https://doi.org/10.3390/s26020520 - 13 Jan 2026
Viewed by 77
Abstract
Accurate trajectory tracking remains a central challenge in differential-drive mobile robots (DDMRs), particularly when operating under real-world conditions. Model Predictive Control (MPC) provides a powerful framework for this task, but its performance degrades when the robot deviates significantly from the nominal path. To [...] Read more.
Accurate trajectory tracking remains a central challenge in differential-drive mobile robots (DDMRs), particularly when operating under real-world conditions. Model Predictive Control (MPC) provides a powerful framework for this task, but its performance degrades when the robot deviates significantly from the nominal path. To address this limitation, robust recovery mechanisms are required to ensure stable and precise tracking. This work presents an experimental validation of an MPC controller applied to a four-wheel DDMR, whose odometry is corrected by a SLAM algorithm running in ROS 2. The MPC is formulated as a quadratic program with state and input constraints on linear (v) and angular (ω) velocities, using a prediction horizon of Np=15 future states, adjusted to the computational resources of the onboard computer. A novel dynamic look-ahead re-entry strategy is proposed, which activates when the robot exits a predefined lateral error band (δ=0.05 m) and interpolates a smooth reconnection trajectory based on a forward look-ahead point, ensuring gradual convergence and avoiding abrupt re-entry actions. Accuracy was evaluated through lateral and heading errors measured via geometric projection onto the nominal path, ensuring fair comparison. From these errors, RMSE, MAE, P95, and in-band percentage were computed as quantitative metrics. The framework was tested on real hardware at 50 Hz through 5 nominal experiments and 3 perturbed experiments. Perturbations consisted of externally imposed velocity commands at specific points along the path, while configuration parameters were systematically varied across trials, including the weight R, smoothing distance Lsmooth, and activation of the re-entry strategy. In nominal conditions, the best configuration (ID 2) achieved a lateral RMSE of 0.05 m, a heading RMSE of 0.06 rad, and maintained 68.8% of the trajectory within the validation band. Under perturbations, the proposed strategy substantially improved robustness. For instance, in experiment ID 6 the robot sustained a lateral RMSE of 0.12 m and preserved 51.4% in-band, outperforming MPC without re-entry, which suffered from larger deviations and slower recoveries. The results confirm that integrating MPC with the proposed re-entry strategy enhances both accuracy and robustness in DDMR trajectory tracking. By combining predictive control with a spatially grounded recovery mechanism, the approach ensures consistent performance in challenging scenarios, underscoring its relevance for reliable mobile robot navigation in uncertain environments. Full article
(This article belongs to the Section Sensors and Robotics)
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32 pages, 946 KB  
Review
Paper-Based Microfluidic Chips for At-Home Point-of-Care Nucleic Acid Testing: Applications and Challenges
by Hao Liu, Yuhan Jia, Yitong Jiang, You Nie and Rongzhang Hao
Diagnostics 2026, 16(2), 251; https://doi.org/10.3390/diagnostics16020251 - 13 Jan 2026
Viewed by 187
Abstract
Along with the growing demands for personalized medicine and public health surveillance, diagnostic technologies capable of rapid and accurate pathogen nucleic acid testing in home settings are becoming increasingly crucial. Paper-based microfluidic chips (μPADs) have emerged as a potential core platform for enabling [...] Read more.
Along with the growing demands for personalized medicine and public health surveillance, diagnostic technologies capable of rapid and accurate pathogen nucleic acid testing in home settings are becoming increasingly crucial. Paper-based microfluidic chips (μPADs) have emerged as a potential core platform for enabling molecular testing at home, owing to their advantages of low cost, portability, and independence from complex instrumentation. However, significant challenges remain in the current μPADs systems regarding nucleic acid extraction efficiency, isothermal amplification stability, and signal readout standardization, which hinder their practical and large-scale application. This review systematically summarizes recent research progress in μPADs for home-based nucleic acid testing from four key aspects: extraction–amplification–detection system integration, with a particular focus on the synergistic effects and development trends of critical technologies such as material engineering, fluid control, signal transduction, and intelligent readout. We further analyze typical application cases of this technology in the rapid screening of infectious disease. Promising optimization pathways are proposed, focusing on standardized manufacturing, cold-chain-independent storage, and AI-assisted result interpretation, aiming to provide a feasible framework and forward-looking perspectives for constructing home-based molecular diagnostic systems. Full article
(This article belongs to the Special Issue Point-of-Care Testing (POCT) for Infectious Diseases)
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34 pages, 5342 KB  
Review
Artificial Intelligence in Medical Diagnostics: Foundations, Clinical Applications, and Future Directions
by Dorota Bartusik-Aebisher, Daniel Roshan Justin Raj and David Aebisher
Appl. Sci. 2026, 16(2), 728; https://doi.org/10.3390/app16020728 - 10 Jan 2026
Viewed by 316
Abstract
Artificial intelligence (AI) is rapidly transforming medical diagnostics by allowing for early, accurate, and data-driven clinical decision-making. This review provides an overview of how machine learning (ML), deep learning, and emerging multimodal foundation models have been used in diagnostic procedures across imaging, pathology, [...] Read more.
Artificial intelligence (AI) is rapidly transforming medical diagnostics by allowing for early, accurate, and data-driven clinical decision-making. This review provides an overview of how machine learning (ML), deep learning, and emerging multimodal foundation models have been used in diagnostic procedures across imaging, pathology, molecular analysis, physiological monitoring, and electronic health record (EHR)-integrated decision-support systems. We have discussed the basic computational foundations of supervised, unsupervised, and reinforcement learning and have also shown the importance of data curation, validation metrics, interpretability methods, and feature engineering. The use of AI in many different applications has shown that it can find abnormalities and integrate some features from multi-omics and imaging, which has shown improvements in prognostic modeling. However, concerns about data heterogeneity, model drift, bias, and strict regulatory guidelines still remain and are yet to be addressed in this field. Looking forward, future advancements in federated learning, generative AI, and low-resource diagnostics will pave the way for adaptable and globally accessible AI-assisted diagnostics. Full article
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22 pages, 341 KB  
Review
The Role of Artificial Intelligence in Enhancing ESG Disclosure Quality in Accounting
by Jiacheng Liu, Ye Yuan and Zhelun Zhu
J. Risk Financial Manag. 2026, 19(1), 58; https://doi.org/10.3390/jrfm19010058 - 9 Jan 2026
Viewed by 283
Abstract
As corporate sustainability reporting evolves into a pivotal resource for investors, regulators, and stakeholders, the imperative to evaluate and elevate ESG disclosure quality intensifies amid persistent challenges like opacity, inconsistency, and greenwashing. This review synthesizes interdisciplinary insights from accounting, finance, and computational linguistics [...] Read more.
As corporate sustainability reporting evolves into a pivotal resource for investors, regulators, and stakeholders, the imperative to evaluate and elevate ESG disclosure quality intensifies amid persistent challenges like opacity, inconsistency, and greenwashing. This review synthesizes interdisciplinary insights from accounting, finance, and computational linguistics on artificial intelligence (AI), particularly natural language processing (NLP) and machine learning (ML), as a transformative force in this domain. We delineate ESG disclosure quality across four operational dimensions: readability, comparability, informativeness, and credibility. By integrating cutting-edge methodological innovations (e.g., transformer-based models for semantic analysis), empirical linkages between AI-extracted signals and market/governance outcomes, and normative discussions on AI’s auditing potential, we demonstrate AI’s efficacy in scaling measurement, harmonizing heterogeneous narratives, and prototyping greenwashing detection. Nonetheless, causal evidence linking managerial AI adoption to stakeholder-perceived enhancements remains limited, compounded by biases in multilingual applications and interpretability deficits. We propose a forward-looking agenda, prioritizing cross-lingual benchmarking, curated greenwashing datasets, AI-assurance pilots, and interpretability standards, to harness AI for substantive, equitable improvements in ESG reporting and accountability. Full article
25 pages, 21050 KB  
Article
Predicting ESG Scores Using Machine Learning for Data-Driven Sustainable Investment
by Sanskruti Patel, Abhay Nath and Pranav Desai
Analytics 2026, 5(1), 7; https://doi.org/10.3390/analytics5010007 - 9 Jan 2026
Viewed by 217
Abstract
Environmental, social and governance (ESG) metrics increasingly inform sustainable investment yet suffer from inter-rater heterogeneity and incomplete reporting, limiting their utility for forward-looking allocation. In this study, we developed and validated a two-level stacked-ensemble machine-learning framework to predict total ESG risk scores for [...] Read more.
Environmental, social and governance (ESG) metrics increasingly inform sustainable investment yet suffer from inter-rater heterogeneity and incomplete reporting, limiting their utility for forward-looking allocation. In this study, we developed and validated a two-level stacked-ensemble machine-learning framework to predict total ESG risk scores for S&P 500 firms using a comprehensive feature set comprising pillar sub-scores, controversy measures, firm financials, categorical descriptors and geospatial environmental indicators. Data pre-processing combined median/mean imputation, one-hot encoding, normalization and rigorous feature engineering; models were trained with an 80:20 train–test split and hyperparameters tuned by k-fold cross-validation. The stacked ensemble substantially outperformed single-model baselines (RMSE = 1.006, MAE = 0.664, MAPE = 3.13%, R2 = 0.979, CV_RMSE_Mean = 1.383, CV_R2_Mean = 0.957), with LightGBM and gradient boosting as competitive comparators. Permutation importance and correlation analysis identified environmental and social components as primary drivers (environmental importance = 0.41; social = 0.32), with potential multicollinearity between component and aggregate scores. This study concludes that ensemble-based predictive analytics can produce reliable, actionable ESG estimates to enhance screening and prioritization in sustainable investment, while recommending human review for extreme predictions and further work to harmonize cross-provider score divergence. Full article
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38 pages, 8537 KB  
Review
Towards Next-Generation Smart Seed Phenomics: A Review and Roadmap for Metasurface-Based Hyperspectral Imaging and a Light-Field Platform for 3D Reconstruction
by Jingrui Yang, Qinglei Zhao, Shuai Liu, Jing Guo, Fengwei Guan, Shuxin Wang, Qinglong Hu, Qiang Liu, Qi Song, Mingdong Zhu and Chao Li
Photonics 2026, 13(1), 61; https://doi.org/10.3390/photonics13010061 - 8 Jan 2026
Viewed by 300
Abstract
Seed phenomics is a critical research field for understanding seed germination mechanisms. Metasurfaces, composed of subwavelength nanostructures, offer a promising pathway to achieve both dispersion control and imaging functionalities within an ultra-compact form factor. Recent advances in micro–nano-optics and computational imaging have opened [...] Read more.
Seed phenomics is a critical research field for understanding seed germination mechanisms. Metasurfaces, composed of subwavelength nanostructures, offer a promising pathway to achieve both dispersion control and imaging functionalities within an ultra-compact form factor. Recent advances in micro–nano-optics and computational imaging have opened new avenues for high-dimensional, multimodal imaging. However, conventional hyperspectral and light-field systems still face limitations in compactness, depth resolution, and spectral–spatial integration. This review summarizes recent progress in metalens and metasurface lens array-based light-field systems for hyperspectral imaging and 3D reconstruction, with a focus on the underlying principles, design strategies, and reconstruction algorithms that enable single-shot 3D hyperspectral acquisition. We further present a forward-looking roadmap toward the realization of a revolutionized imaging paradigm: a metasurface-based light-field platform that fully integrates 3D and hyperspectral imaging capabilities. In particular, we examine how dispersive metasurfaces serve as core optical elements for precise dispersion control in hyperspectral imaging systems, while metalens arrays enable accurate modulation of spatial–angular distributions in light-field configurations. We systematically review both 3D and spectral reconstruction algorithms, highlighting their roles in decoding complex optical encodings. The application of these integrated systems in seed phenotyping is emphasized, demonstrating their capability to capture 3D spatial–spectral distributions in a single exposure. This approach facilitates high-throughput analysis of morphological traits, germination potential, and internal biochemical composition, offering a comprehensive solution for advanced seed characterization. Finally, we outline a practical roadmap for implementing a metasurface-based light-field platform that integrates hyperspectral imaging and computational 3D reconstruction. This review offers a comprehensive overview of the state of the art in compact 3D light-field systems and multimodal hyperspectral imaging platforms, while providing forward-looking insights aimed at advancing smart seed phenotyping, precision agriculture, and next-generation optical imaging technologies. Full article
(This article belongs to the Special Issue Optical Metasurface: Applications in Sensing and Imaging)
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29 pages, 980 KB  
Review
Ketamine in Diabetes Care: Metabolic Insights and Clinical Applications
by Shiryn D. Sukhram, Majandra Sanchez, Ayotunde Anidugbe, Bora Kupa, Vincent P. Edwards, Muhammad Zia and Grozdena Yilmaz
Pharmaceutics 2026, 18(1), 81; https://doi.org/10.3390/pharmaceutics18010081 - 8 Jan 2026
Viewed by 278
Abstract
Background: Depression and diabetic neuropathy (DN) commonly complicate diabetes and impair glycemic control and quality of life. Ketamine and its S-enantiomer, esketamine, provide rapid antidepressant and analgesic effects, yet diabetes-related pathophysiology and co-therapies may modify exposure, response, and safety. Methods: We conducted a [...] Read more.
Background: Depression and diabetic neuropathy (DN) commonly complicate diabetes and impair glycemic control and quality of life. Ketamine and its S-enantiomer, esketamine, provide rapid antidepressant and analgesic effects, yet diabetes-related pathophysiology and co-therapies may modify exposure, response, and safety. Methods: We conducted a scoping review following PRISMA-ScR. MEDLINE/PubMed, CINAHL, and APA PsycInfo were searched (January 2020–31 May 2025). Eligible human and animal studies evaluated ketamine, esketamine, or norketamine in the context of diabetes (type 1 [T1DM], type 2 [T2DM], gestational [GDM]), or DN, and reported psychiatric, analgesic, metabolic, or mechanistic outcomes. Two reviewers independently screened and charted data; no formal risk-of-bias assessment was performed. Results: Eleven studies met inclusion criteria: four human case reports/series (three T1DM, one T2DM), one randomized trial in GDM, two narrative reviews of topical ketamine for DN, and four preclinical rodent studies using streptozotocin- or diet-induced diabetes models. Short-term improvements were reported for treatment-resistant depression and neuropathic pain, including opioid-sparing postoperative analgesia in GDM. Glycemic effects varied across settings, with both hyperglycemia and hypoglycemia reported. Mechanistic and clinical drug–drug and drug-disease interactions (particularly involving metformin, GLP-1 receptor agonists, SGLT2 inhibitors, and CYP3A4/CYP2B6 modulators) remain insufficiently studied. We outline a forward-looking population pharmacokinetic (popPK) and pharmacokinetic-pharmacodynamic (PK-PD) research agenda, including priority covariates (eGFR, hepatic function, inflammatory status, HbA1c, genotype, co-medications) and sparse-sampling windows for future model-informed precision dosing. Conclusions: Current evidence supports cautious, selective use of ketamine for refractory depression and DN within multidisciplinary diabetes care. Purpose-built popPK/PK-PD studies in both human and preclinical diabetic models cohorts are needed to quantify variability, define drug–disease–drug interactions and glycemic risk, and inform individualized dosing strategies. Full article
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23 pages, 5175 KB  
Article
Landslide Disaster Vulnerability Assessment and Prediction Based on a Multi-Scale and Multi-Model Framework: Empirical Evidence from Yunnan Province, China
by Li Xu, Shucheng Tan and Runyang Li
Land 2026, 15(1), 119; https://doi.org/10.3390/land15010119 - 7 Jan 2026
Viewed by 218
Abstract
Against the backdrop of intensifying global climate change and expanding human encroachment into mountainous regions, landslides have increased markedly in both frequency and destructiveness, emerging as a key risk to socio-ecological security and development in mountain areas. Rigorous assessment and forward-looking prediction of [...] Read more.
Against the backdrop of intensifying global climate change and expanding human encroachment into mountainous regions, landslides have increased markedly in both frequency and destructiveness, emerging as a key risk to socio-ecological security and development in mountain areas. Rigorous assessment and forward-looking prediction of landslide disaster vulnerability (LDV) are essential for targeted disaster risk reduction and regional sustainability. However, existing studies largely center on landslide susceptibility or risk, often overlooking the dynamic evolution of adaptive capacity within affected systems and its nonlinear responses across temporal and spatial scales, thereby obscuring the complex mechanisms underpinning LDV. To address this gap, we examine Yunnan Province, a landslide-prone region of China where intensified extreme rainfall and the expansion of human activities in recent years have exacerbated landslide risk. Drawing on the vulnerability scoping diagram (VSD), we construct an exposure–sensitivity–adaptive capacity assessment framework to characterize the spatiotemporal distribution of LDV during 2000–2020. We further develop a multi-model, multi-scale integrated prediction framework, benchmarking the predictive performance of four machine learning algorithms—backpropagation neural network (BPNN), support vector machine (SVM), random forest (RF), and XGBoost—across sample sizes ranging from 2500 to 360,000 to identify the optimal model–scale combination. From 2000 to 2020, LDV in Yunnan declined overall, exhibiting a spatial pattern of “higher in the northwest and lower in the southeast.” High-LDV areas decreased markedly, and sustained enhancement of adaptive capacity was the primary driver of the decline. At approximately the 90,000-cell grid scale, XGBoost performed best, robustly reproducing the observed spatiotemporal evolution and projecting continued declines in LDV during 2030–2050, albeit with decelerating improvement; low-LDV zones show phased fluctuations of “expansion followed by contraction”, whereas high-LDV zones continue to contract northwestward. The proposed multi-model, multi-scale fusion framework enhances the accuracy and robustness of LDV prediction, provides a scientific basis for precise disaster risk reduction strategies and resource optimization in Yunnan, and offers a quantitative reference for resilience building and policy design in analogous regions worldwide. Full article
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34 pages, 575 KB  
Article
Spatial Stress Testing and Climate Value-at-Risk: A Quantitative Framework for ICAAP and Pillar 2
by Francesco Rania
J. Risk Financial Manag. 2026, 19(1), 48; https://doi.org/10.3390/jrfm19010048 - 7 Jan 2026
Viewed by 143
Abstract
This paper develops a quantitative framework for climate–financial risk measurement that combines a spatially explicit jump–diffusion asset–loss model with prudentially aligned risk metrics. The approach connects regional physical hazards and transition variables derived from climate-consistent pathways to asset returns and credit parameters through [...] Read more.
This paper develops a quantitative framework for climate–financial risk measurement that combines a spatially explicit jump–diffusion asset–loss model with prudentially aligned risk metrics. The approach connects regional physical hazards and transition variables derived from climate-consistent pathways to asset returns and credit parameters through the use of climate-adjusted volatilities and jump intensities. Fat tails and geographic heterogeneity are captured by it, which conventional diffusion-based or purely narrative stress tests fail to reflect. The framework delivers portfolio-level Spatial Climate Value-at-Risk (SCVaR) and Expected Shortfall (ES) across scenario–horizon matrices and incorporates an explicit robustness layer (block bootstrap confidence intervals, unconditional/conditional coverage backtests, and structural-stability tests). All ES measures are understood as Conditional Expected Shortfall (CES), i.e., tail expectations evaluated conditional on climate stress scenarios. Applications to bank loan books, pension portfolios, and sovereign exposures show how climate shocks reprice assets, alter default and recovery dynamics, and amplify tail losses in a region- and sector-dependent manner. The resulting, statistically validated outputs are designed to be decision-useful for Internal Capital Adequacy Assessment Process (ICAAP) and Pillar 2: climate-adjusted capital buffers, scenario-based stress calibration, and disclosure bridges that complement alignment metrics such as the Green Asset Ratio (GAR). Overall, the framework operationalises a move from exposure tallies to forward-looking, risk-sensitive, and auditable measures suitable for supervisory dialogue and internal risk appetite. Full article
(This article belongs to the Special Issue Climate and Financial Markets)
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26 pages, 9258 KB  
Article
TriGEFNet: A Tri-Stream Multimodal Enhanced Fusion Network for Landslide Segmentation from Remote Sensing Imagery
by Zirui Zhang, Qingfeng Hu, Haoran Fang, Wenkai Liu, Ruimin Feng, Shoukai Chen, Qifan Wu, Peng Wang and Weiqiang Lu
Remote Sens. 2026, 18(2), 186; https://doi.org/10.3390/rs18020186 - 6 Jan 2026
Viewed by 314
Abstract
Landslides are among the most prevalent geological hazards worldwide, posing severe threats to public safety due to their sudden onset and destructive potential. The rapid and accurate automated segmentation of landslide areas is a critical task for enhancing capabilities in disaster risk assessment, [...] Read more.
Landslides are among the most prevalent geological hazards worldwide, posing severe threats to public safety due to their sudden onset and destructive potential. The rapid and accurate automated segmentation of landslide areas is a critical task for enhancing capabilities in disaster risk assessment, emergency response, and post-disaster management. However, existing deep learning models for landslide segmentation predominantly rely on unimodal remote sensing imagery. In complex Karst landscapes characterized by dense vegetation and severe shadow interference, the optical features of landslides are difficult to extract effectively, thereby significantly limiting recognition accuracy. Therefore, synergistically utilizing multimodal data while mitigating information redundancy and noise interference has emerged as a core challenge in this field. To address this challenge, this paper proposes a Triple-Stream Guided Enhancement and Fusion Network (TriGEFNet), designed to efficiently fuse three data sources: RGB imagery, Vegetation Indices (VI), and Slope. The model incorporates an adaptive guidance mechanism within the encoder. This mechanism leverages the terrain constraints provided by slope to compensate for the information loss within optical imagery under shadowing conditions. Simultaneously, it integrates the sensitivity of VIs to surface destruction to collectively calibrate and enhance RGB features, thereby extracting fused features that are highly responsive to landslides. Subsequently, gated skip connections in the decoder refine these features, ensuring the optimal combination of deep semantic information with critical boundary details, thus achieving deep synergy among multimodal features. A systematic performance evaluation of the proposed model was conducted on the self-constructed Zunyi dataset and two publicly available datasets. Experimental results demonstrate that TriGEFNet achieved mean Intersection over Union (mIoU) scores of 86.27% on the Zunyi dataset, 80.26% on the L4S dataset, and 89.53% on the Bijie dataset, respectively. Compared to the multimodal baseline model, TriGEFNet achieved significant improvements, with maximum gains of 7.68% in Recall and 4.37% in F1-score across the three datasets. This study not only presents a novel and effective paradigm for multimodal remote sensing data fusion but also provides a forward-looking solution for constructing more robust and precise intelligent systems for landslide monitoring and assessment. Full article
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