Search Results (1,256)

As a key form of deep foundation in civil engineering, the concrete pouring quality of cast-in-place piles directly determines the integrity and long-term bearing performance of the pile body. Accurate monitoring of the pouring interface is critical to preventing defects such as mud inclusion and pile breakage. To address the limitations of existing monitoring methods for concrete pouring interfaces, this paper proposes a full-pulse acoustic monitoring method for the concrete pouring interface of cast-in-place piles. Firstly, by constructing a hardware system platform consisting of “multi-level in-borehole sound sources + interface acoustic wave sensors + orifice full-pulse receivers + ground processors”, differential capture of signals propagating at different depths is achieved through multi-frequency excitation. Subsequently, a waveform data processing method is proposed to realize denoising, enhancement, and frequency discrimination of different signals, and a target feature recognition model that integrates cross-correlation functions and signal similarity analysis is established. Finally, by leveraging the differential characteristics of measurement signals at different depths, a near-field measurement mode and a far-field measurement mode are developed, thereby establishing a calculation model for the elevation position of the pouring interface under different scenarios. Meanwhile, the feasibility of the proposed method is verified through practical engineering cases. The results indicate that the proposed full pulse acoustic monitoring method can achieve non-destructive, real-time, and high-precision monitoring of the pouring interface, providing an effective technical approach for quality control in pile foundation construction and exhibiting broad application prospects. Full article

This study focuses on the susceptibility and surface degradation of low-alloy carbon steel 42CrMo4 to corrosion and cavitation erosion, as this steel is widely used in marine environments with aggressive chemical species and harsh conditions. Due to its high strength and fatigue resistance, 42CrMo4 steel is often employed in offshore mechanical components such as shafts and fasteners as well as crane parts in ports and harbors. Various experimental methods, including corrosion and cavitation tests, were used to assess the steel’s surface integrity under extreme conditions. Surface changes were monitored using modern analytical tools for precise assessments, including image and morphological analyses, to quantify degradation levels and specific parameters of defects induced by corrosion and cavitation. Non-destructive techniques such as optical microscopy (OM), scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), and image analysis software were employed for the quantitative assessment of morphological parameters and elemental analysis. EDS analysis revealed changes in elemental composition, indicating corrosion products that caused significant mass loss and defect formation, with degradation increasing over time. The average corrosion rate of 42CrMo4 steel in a 3.5% NaCl solution reached a peak value of 0.846 mm/year after 120 days of exposure. Cavitation erosion behavior was measured based on mass loss, indicating the occurrence of different cavitation periods, with the steady-state period achieved after 60 min. The number of formed pits increased until 120 min, after which it decreased slightly. This indicates that a time frame of 120 min was identified as significant for changes in the mechanism of pit formation. Specifically, up to 120 min, pit formation was the dominant mechanism of cavitation erosion, while after that, as the number of pits slightly declined, the growth and merging of formed pits became the dominant mechanism. The cavitation erosion tests showed mass loss and mechanical damage, characterized by the formation of pits and cavities. The findings indicate that the levels of surface degradation were higher for corrosion than for cavitation. The presented approach also provides an assessment of the degradation mechanisms of 42CrMo4 steel exposed to corrosive and cavitation conditions. Full article

Salt efflorescence is always a main barrier for pottery cultural relic conservation. This study presents an innovative two-step process for enhancing the reinforced strength of efflorescence pottery. The first step involves forming a cross-linked mesh structure on the weathered surfaces using ethyl orthosilicate hydrolysate as an organic reinforcement material. In the second step, a two-component inorganic reinforcement material is developed to transform the destructive salt into a filling reinforcement material. The reinforcement pottery was comparatively investigated by XRD, color difference analysis, penetration depth measurements, mechanical strength tests, permeability assessment, and surface morphology characterization. The results demonstrate that the optimized reinforcement material exhibits high water permeability (up to 2.5 cm in penetration depth), stable color variation (ΔE up to 1.44), and excellent mechanical properties (17.01 MPa compressive strength and 2.66 MPa flexural strength). This work presents a promising technique for enhancing the structural interlocking between reinforcement pottery, which is crucial for mitigating dominant salt damage, and suggests an effective strategy that is applicable to the protection of cultural relics. Full article

At present, traditional X-ray inspection is used to inspect the welds of the bottom, barrel section and short shell parts of the launch vehicle, which has the disadvantages of low automation, complicated process and low efficiency, and cannot meet the fast-paced development needs of multiple models at present. Moreover, the degree of digitization is low, the test results are recorded in the form of negatives, data statistics, storage and access are difficult, and the circulation efficiency is low, which is not conducive to product quality control and traceability; At the same time, it cannot adapt to and meet the needs of digital and intelligent transformation and development. In this paper, a dual-robot collaborative digital radiographic inspection system for rocket tank welds is developed by combining dual-robot control technology and digital radiographic inspection technology. The system can be directly applied to digital radiographic inspection of tank bottom, barrel section and short shell welds of multiple types of launch vehicles; meanwhile, the dual-robot path planning technology based on the dual-mode is studied. Finally, the imaging software platform based on VS and Twincat3.0 VS2015 software combined with QT upper computer is designed. Experiments show that compared with the existing traditional ray detection methods, the detection efficiency of the system is improved by 5 times, the image sensitivity reaches W14, the resolution reaches D10, and the standardized signal-to-noise ratio reaches 128, which far exceeds the requirements of process technology A, and meets the current non-destructive detection work of multi-model rocket tank welds. Full article

Social media-based content entrepreneurship is evolving rapidly and emerging as a significant and growing form of employment. Generative AI (GenAI) offers content entrepreneurs a powerful tool for content creation; however, the technology can be abused to produce deepfakes, rumors, plagiarism, and other injurious content. This triggers value co-destruction across the creator economy and society, making it particularly crucial to enhance content entrepreneurs’ compliance with GenAI policies. Aiming to develop an effective governance framework, this study adopts a mixed-methods approach, beginning with exploratory interviews to uncover factors affecting GenAI policy compliance intention. Subsequently, it employs confirmatory quantitative research with a survey to validate the proposed research model. The results indicate that both the deterrence triad (i.e., perceived sanction certainty, severity, and celerity) and perceived social norm strengthen GenAI policy compliance intention. Meanwhile, perceived social norm weakens the impact of perceived sanction certainty on policy compliance intention. Furthermore, peer communication enhances policy compliance intention by increasing perceptions of sanction certainty and celerity as well as social norm. These findings contribute to the sustainable development of content entrepreneurship and effective GenAI governance, fostering a symbiotic creator economy. Full article

The Chang 7 member of the Ordos Basin hosts abundant shale oil and gas resources and plays a vital role in the development of unconventional energy. This study investigates differences in damage evolution and underlying mechanisms between representative shale oil and shale gas reservoir cores from the Chang 7 member under fracturing fluid hydration. A combination of high-temperature expansion tests, nuclear magnetic resonance (NMR), and micro-computed tomography (Micro-CT) was used to systematically characterize macroscopic expansion behavior and microscopic pore structure evolution. Results indicate that shale gas cores undergo faster expansion and higher imbibition rates during hydration (reaching stability in 10 h vs. 23 h for shale oil cores), making them more vulnerable to water-lock damage, while shale oil cores exhibit slower hydration but more pronounced pore structure reconstruction. After 72 h of immersion in fracturing fluid, both core types experienced reduced pore volumes and structural reorganization; however, shale oil cores demonstrated greater capacity for pore reconstruction, with a newly formed pore volume fraction of 34.5% compared to 24.6% for shale gas cores. NMR and Micro-CT analyses reveal that hydration is not merely a destructive process but a dynamic “damage–reconstruction” evolution. Furthermore, the addition of clay stabilizers effectively mitigates water sensitivity and preserves pore structure, with 0.7% identified as the optimal concentration. The research results not only reveal the differential response law of fracturing fluid damage in the Chang 7 shale reservoir but also provide a theoretical basis and technical support for optimizing fracturing fluid systems and achieving differential production increases. Full article

The architectural settlements of the Dong people are the core representatives of China’s Dong culture. The unique architectural forms created by the Dong people, such as stilted houses, drum towers, and wind-and-rain bridges, demonstrate the wisdom of the Dong people in adapting to mountainous environments and their exquisite construction techniques. However, with the acceleration of urbanization and the impact of tourism development, Dong village architecture is facing multiple challenges, including settlement hollowing-out, the discontinuity of traditional craftsmanship, and the destruction of authenticity. This study proposes a series of protection and restoration strategies by integrating relevant domestic and international theories and practical experiences based on the formal characteristics, cultural value, and current issues of Dong village settlement architecture. It emphasizes the principle of holistic protection, advocates for the combination of authentic restoration and adaptive renewal, and aims to achieve the inheritance of cultural heritage through means such as digital technology, community participation mechanisms, and cross-regional collaborative protection. Furthermore, this study explores the path toward balancing traditional architecture with modern needs, intending to provide theoretical support and a practical reference for the sustainable protection of Dong village settlement architecture and the continuation of cultural memory. Full article

To address the issue of insufficient contrast in conventional X-ray absorption imaging for biological soft tissues and weakly absorbing materials, this paper proposes a beam tracking X-ray phase-contrast imaging system using a conventional X-ray source. A periodic pinhole array mask is placed between the X-ray source and the sample to spatially modulate the X-ray beam, dividing it into multiple independent sub-beams. Each sub-beam is deflected due to the modulation effect of the sample, resulting in slight positional shifts in the intensity patterns formed on the detector. The experiments employ an X-ray source with a 400 μm focal spot and use a two-dimensional step-scanning approach to acquire image sequences of various samples. The experimental results show that this method can extract the edge profile and structural changes in the samples to some extent, and it demonstrates good contrast and detail recovery under weak absorption conditions. These results suggest that this method has certain application potential in material inspection, non-destructive testing, and related fields. Full article

The aim of the present study is to investigate the mechanism behind corrosion destruction in laser-melted layers (LMLs) of AISI 321 austenitic stainless steel after electrochemical corrosion in Ringer’s solution. Surface morphology, microstructure, chemical composition, grain sizes, and orientation are studied using OM, SEM, EDS, and EBSD. It was confirmed that (1) the main mechanism behind corrosion destruction is identical between untreated and laser-melted steel, i.e., the selective destruction of the lower corrosion resistance phase (δ-ferrite) in the form of pits, and (2) the morphology and size of corrosion pits are different, as determined via δ-ferrite morphology, with narrow deep pits of uneven shape observed on the surface of wrought steel and rounded shallower pits seen in LML. The following mechanism is proposed with regard to corrosion destruction in LML: (1) the initial destruction of δ-ferrite; (2) the formation of an austenitic dendrite network; (3) the mechanical fracture of austenitic dendrites and pit formation; and (4) the growth of pits inside the grain. The following relationship between corrosion pit development and dendrite orientation in the LML is observed: (1) In the melted zone, with dendrite axes perpendicular to or inclined toward the surface, the corrosion pit grows within the grain. (2) At the melted zone/base metal (MZ/BM) boundary, with dendrite axes parallel to the surface, the corrosion pit develops in the heat-affected zone, along the MZ/BM boundary. Full article

Dioryctria abietella (Lepidoptera: Pyralidae) is a destructive forest pest for coniferous trees. Bacillus thuringiensis has been widely applied in forestry as a biological control agent to control it. However, the mechanisms of Bt-induced mortality in D. abietella, particularly its effects on gene expression and enzyme activities, remain unclear. Here, bioassay, enzyme assay, transcriptome sequencing, and gene expression profiling were employed to explore the relationship between the toxin-receptor, defense, and lethal mechanisms of D. abietella after Bt exposure. In a toxicity bioassay, Bacillus thuringiensis galleriae 05041 strain (Bt05041) was the most toxic insecticide to the larvae of D. abietella, with LC₅₀ values of 3.15 × 10⁸ Colony-Forming Units (CFUs) mL⁻¹ at 72 h after treatment. Transcriptome analysis revealed that the gene expression patterns of D. abietella after 8 h of Bt05041 exposure (Bt8) varied considerably from the Bt05041-treated for 2 h group (Bt2). In the Bt2 group, differentially expressed genes were significantly enriched in cellular and bioenergy pathways of lysosome, insulin signaling, cGMP-PKG signaling, etc. Immune-related pathways were activated, namely cAMP, AMPK, MAPK, Rap1, IMD, and Toll pathways. Meanwhile, Bt8 treatment caused metabolic changes in basic substances such as amino acids, glucose, nucleic acids, and fatty acids. Bt05041 exposure activated the activities of defense enzymes and induced gene expression changes in D. abietella larvae. Among them, most Bt-receptor genes had higher expression levels than defense enzyme genes. Overall, these findings reveal a possible mechanism underlying Bt-mediated death in D. abietella larvae. This work provides valuable information in terms of biological control strategies. Full article

Akaganeite is the most destructive corrosion product in a rust layer, and it accelerates the corrosion rate of steel in certain atmospheres. Until now, considerable controversy has existed regarding the conditions required for its formation and its mechanism of formation. In this work, the formation of akaganeite in the specific corrosion process, which was atmospheric corrosion induced by NaCl deliquescence, was investigated through simulated experiments in a laboratory setting. Stereoscopic microscopy and scanning electron microscopy were employed to characterize the morphologies of the corrosion products, which could illuminate the morphological features of the electrolyte induced by the NaCl particles. The constituents of rust in a single droplet were analyzed by micro-Raman spectroscopy, and the components of the corrosion phases on a macroscopic scale were analyzed by XRD. The results indicate that the deliquescence of NaCl particles caused droplets to form around them, and atmospheric corrosion occurred in each droplet independently. Akaganeite can form during atmospheric corrosion induced by NaCl particles in the early stage within 12 h. The initial corrosion products, lepidocrocite and magnetite, increase the amount of akaganeite formed. The amount of salt deposited also plays an essential role in the formation of akaganeite on a macroscopic scale. Full article

Background: Onychomycosis responds poorly to topical therapy, and efinaconazole (EFN) has low aqueous solubility. Methods: This study aimed to develop a 10% w/w EFN self-nanoemulsifying system (SNEDDS) with improved solubility, permeation, antifungal activity, and stability. Excipients were screened by EFN saturation solubility. An MCT oil/Solutol HS 15/Labrafil M2125 CS SNEDDS (5/75/20, w/w) was optimized via a pseudo-ternary diagram. Characterization included droplet size, PDI, and zeta potential, morphology, and drug–excipient compatibility. Solubility was measured across pH. Permeation of EFN SNEDDS vs. EFN suspension was tested by Franz diffusion cells. Antifungal activity against Trichophyton rubrum and Trichophyton mentagrophytes was assessed by paper-disc diffusion, and hyphal damage on human nails was examined by SEM. Stability was studied for six months under room, accelerated, and stress conditions. Results: The optimized SNEDDS formed sub-50 nm droplets with low polydispersity and favourable zeta potential. Solubility was maintained across pH, and cumulative permeation increased 13.6-fold versus suspension. Paper-disc assays showed larger inhibition zones at lower EFN doses. SEM on human nails revealed marked hyphal destruction. TEM confirmed spherical nanoemulsion droplets. FT-IR showed no new peaks, supporting compatibility. Particle size, PDI, zeta potential, and drug content remained stable over six months under all storage conditions. Conclusions: A 10% w/w EFN SNEDDS enhanced solubility, transungual permeation, and antifungal efficacy while maintaining robust stability, supporting its potential as an ethanol-free therapy for onychomycosis. Full article

Background: Diabetes mellitus (DM), periodontal disease (PD), and cardiovascular disease (CVD) are highly prevalent global health conditions with overlapping pathophysiological mechanisms. Emerging evidence suggests a bidirectional and synergistic relationship among them, driven by chronic inflammation, immune dysregulation, oxidative stress, and microbial dysbiosis. Objective: This review synthesizes current literature on the interconnectedness of DM, PD, and CVD, emphasizing shared molecular pathways, clinical implications, and opportunities for integrated management. Methods: A systematic review and narrative synthesis of recent clinical trials, observational studies, and multi-omics investigations was conducted to explore the mechanisms linking these three conditions. A structured literature search was performed across PubMed, Scopus, and Web of Science from database inception until 30 June 2025. Key findings were contextualized within systems biology, precision medicine, and real-world clinical strategies. Results: DM exacerbates periodontal inflammation and accelerates tissue destruction via hyperglycemia-induced inflammatory mediators, while periodontitis worsens glycemic control and insulin resistance. Both conditions independently elevate cardiovascular risk, and their co-occurrence significantly amplifies the incidence of adverse cardiovascular events. Shared biomarkers such as Interleukin (IL)-6, Tumor Necrosis Factor (TNF)-α, and CRP, as well as overlapping genetic and epigenetic signatures, underscore a common inflammatory axis. Periodontal therapy has demonstrated modest but meaningful benefits on glycemic control and endothelial function, while cardiometabolic therapies (e.g., statins, Glucagon-Like Peptide (GLP-1) receptor agonists, SGLT2 inhibitors) show potential to improve periodontal outcomes. Probiotics, microbiome-targeted therapies, and AI-based risk models are emerging as future tools. Conclusions: DM, PD, and CVD form a mutually reinforcing triad mediated by systemic inflammation and metabolic dysregulation. Integrated, multidisciplinary care models and precision health strategies are essential to address this inflammatory burden and improve long-term outcomes. Further large-scale interventional trials and mechanistic human studies are needed to establish causal links and optimize combined therapeutic approaches. Full article

Earthquakes remain among the most destructive natural hazards, causing severe loss of life and property in seismically active regions such as Nepal. Major events such as the 1934 Nepal–Bihar earthquake (M_w 8.2), the 2015 Gorkha earthquake (M_w 7.8), and the 2023 Jajarkot earthquake (M_L 6.4) have repeatedly exposed the vulnerability of Nepal’s built environment. In response, the Ready-to-Use Detailing (RUD) guideline (NBC 205:2024) was introduced to provide standardized structural detailing for low-rise reinforced concrete buildings without masonry infill, particularly for use in areas where access to professional engineering services is limited. This study was motivated by the need to critically assess the structural performance of buildings designed according to such rule-of-thumb detailing, which is widely applied through owner–builder practices. Nonlinear pushover analyses were carried out using finite element modelling for typical configurations on soil types C and D, under peak ground accelerations of 0.25 g, 0.30 g, 0.35 g, and 0.40 g. The response spectrum from NBC 105:2020 was adopted to determine performance points. The analysis focused on global response, capacity curves, storey drift, and hinge formation to evaluate structural resilience. The maximum story drift for the linear static analysis is found to be 0.56% and 0.86% for peak ground acceleration of 0.40 g, for both three and four-storied buildings. Also, from non-linear static analysis, it is found that almost all hinges formed in the beams and columns are in the Immediate Occupancy (IO) level. The findings suggest that the RUD guidelines are capable of providing adequate seismic performance for low-rise reinforced concrete buildings, given that the recommended material quality and construction standards are satisfied. Full article

During the pathological process of spinal cord injury (SCI), ferroptosis is closely related to mitochondrial homeostasis. Following the occurrence of SCI, the interruption of local blood supply leads to mitochondrial damage within cells and a reduction in Adenosine triphosphate (ATP) production. This results in the loss of transmembrane ion gradients, causing an influx of Ca²⁺ into the cells, which in turn generates a significant amount of Reactive oxygen species (ROS) and reactive nitrogen species. This leads to severe mitochondrial dysfunction and an imbalance in mitochondrial homeostasis. Ferroptosis is a form of programmed cell death that differs from other types of apoptosis, as it is dependent on the accumulation of iron and lipid peroxides, along with their byproducts. The double bond structures in intracellular polyunsaturated fatty acids (PUFA) are particularly susceptible to attack by ROS, leading to the formation of lipid alkyl free radicals. This accumulation of lipid peroxides within the cells triggers ferroptosis. After SCI, the triggering of ferroptosis is closely associated with the “death triangle”—a core network that catalyzes cell death through the interaction of three factors: local iron overload, collapse of antioxidant defenses, and dysregulation of PUFA metabolism (where PUFA are susceptible to attack by reactive ROS leading to lipid peroxidation). These three elements interact to form a central network driving cell death. In the pathological cascade of SCI, mitochondria serve as both a major source of ROS and a primary target of their attack, playing a crucial role in the initiation and execution of cellular ferroptosis. Mitochondrial homeostasis imbalance is not only a key inducer of the “death triangle” (such as the intensification of lipid peroxidation by mitochondrial ROS), but is also reverse-regulated by the “death triangle” (such as the destruction of mitochondrial structure by lipid peroxidation products). Through the cascade reaction of this triangular network, mitochondrial homeostasis imbalance and the “death triangle” jointly drive the progression of secondary damage. This study aims to synthesize the mechanisms by which various therapeutic approaches mitigate SCI through targeted regulation of mitochondrial homeostasis and inhibition of ferroptosis. Unlike previous research, we integrate the bidirectional regulatory relationship between “mitochondrial homeostasis disruption” and “ferroptosis” in SCI, and emphasize their importance as a synergistic therapeutic target. We not only elaborate in detail how mitochondrial homeostasis—including biogenesis, dynamics, and mitophagy—modulates the initiation and execution of ferroptosis, but also summarize recent strategies that simultaneously target both processes to achieve neuroprotection and functional recovery. Furthermore, this review highlights the translational potential of various treatments in blocking the pathological cascade driven by oxidative stress and lipid peroxidation. These insights provide a novel theoretical framework and propose combinatory therapeutic approaches, thereby laying the groundwork for designing precise and effective comprehensive treatment strategies for SCI in clinical settings. Full article