Search Results (53)

In response to the growing challenge of electronic waste, we developed an open-source pick-and-remove system for recovering electronic components for reuse. This platform is based on a repurposed 3-D printer chassis, an infrared pre-heater, and a hot-air soldering station. The system is designed for easy adoption in academic laboratories and FabLabs. A literature review highlights the potential of electronic components recovery, while preliminary tests demonstrate high recovery rates and minimal environmental impact of the proposed system. This work aims to support the transition to a circular electronics economy by making component recovery accessible and providing additional value to electronic waste. Full article

Low-cost optical sensors have emerged as promising tools for in situ freshwater quality monitoring, offering the potential to expand spatial and temporal data coverage, particularly in community-based monitoring projects. However, despite rapid technological development of low-cost optical sensors, analytical validation practices of these devices remain poorly studied. This study aims to systematically and critically assess analytical validation practices applied to low-cost optical sensors based on absorbance, fluorescence, colorimetry, and light scattering, potentially designed for community-based freshwater monitoring. A total of 40 studies were analysed to evaluate how key analytical performance parameters, including sensitivity, accuracy, precision, and repeatability, as well as comparison with reference methods or benchtop instruments, were assessed and reported in relation to established validation guidelines. The analysis revealed substantial heterogeneity and critical gaps in validation approaches. While most studies report sensitivity metrics such as limits of detection and quantification, comprehensive evaluation of key analytical parameters such as accuracy, precision, and reproducibility was often limited. The reliance on single calibration experiments and high determination coefficients ($R^2$) frequently overestimates sensor performance. The lack of open-source materials further limits reproducibility and deployment: essential information such as design files, calibration procedures, and open-source resources is often incomplete or unavailable. To address these limitations, we propose a structured framework for validation and reporting that integrates established analytical guidelines with the practicalities of low-cost sensor development. Adoption of this approach would enable more consistent performance evaluation, improving reproducibility and facilitating comparison across studies and devices. Overall, strengthening analytical validation and reporting practices is essential to support the transition of low-cost optical sensors from proof-of-concept systems to reliable analytical devices for freshwater quality monitoring. Full article

Background: Digital surgery integrates advanced imaging, computational modeling, additive manufacturing, and intraoperative navigation technologies. Although widely explored, most platforms remain fragmented and lack regulatory cohesion. The B-onic Platform was conceived as a unified workflow that enables surgical planning, device personalization, and intraoperative navigation within a regulatory-compliant framework. Objective: This study aimed to present a comprehensive single-center clinical evaluation of the implementation of the B-onic Platform in a large single-center cohort, focusing on efficiency, patient safety, and surgeon-reported outcomes. Methods: A retrospective review of 308 consecutive surgical plans was performed at La Paz University Hospital (Madrid, Spain) between 2020 and 2024 and compared with institutional historical controls from 2018 to 2019. Procedures included maxillofacial surgery, traumatology, reconstructive surgery, and other specialties. The platform incorporated imaging-based CAD modeling, 3D-printed biomodels and guides, and immersive validation through the NavigatorPro XR module. Outcomes analyzed were preoperative planning time, operative duration, 30-day complication and rehospitalization rates, intraoperative blood loss, and surgeon-reported perception of anatomical understanding and intraoperative confidence. Results: Mean preoperative planning time was reduced by 34% (−42 h; 95% CI: −48 to −36 h; p < 0.01) compared with historical controls. Mean operative duration decreased from 226 ± 74 min to 181 ± 61 min (−45 min; 95% CI: −52 to −38 min; p < 0.001). The 30-day postoperative complication rate decreased from 12.9% to 10.7% (absolute reduction 2.2%; 95% CI: 0.2–4.1%; p = 0.037), while rehospitalization rates declined from 9.1% to 4.3% (p = 0.012). Mean length of hospital stay decreased from 6.8 ± 3.1 to 5.2 ± 2.3 days (p = 0.022), and intraoperative blood loss was reduced by 12–30% across specialties (p = 0.008). NavigatorPro XR halved validation time for guides and implants (71.8 ± 22.4 h vs. 35.6 ± 18.9 h; p < 0.001). Ninety-two percent of surveyed surgeons reported improved 3D anatomical understanding and enhanced intraoperative safety. Conclusions: The B-onic Platform has transitioned from a prototype to a consolidated system, integrated into routine practice with significant gains in efficiency, safety, and training value. These findings support the potential of the platform as a precision surgery model; however, further multicenter prospective studies are required to confirm scalability. Full article

The Fourth Industrial Revolution has reshaped shared spaces in higher education, with manufacturing labs (Fab Labs) emerging as vital hubs for collaboration. However, a systematic framework for ensuring their long-term sustainability as shared resources is lacking. This study addresses this gap by conceptualizing the university Fab Lab as a ‘commons’ and applying Elinor Ostrom’s Institutional Analysis and Development (IAD) framework. We propose a new analytical framework for sustainable space sharing, reconstructed from Ostrom’s principles into three university policy domains: Resource Policy (Rp), Actor/User Policy (Ap), and Community/Governance Policy (C/Gp). To validate this framework, we conduct a case study of the ‘Idea Factory’ at Seoul National University, analyzing its operational policies in conjunction with global standards like the Fab Charter. The proposed framework provides practical guidance for establishing spatial policies and architectural plans that emphasize autonomy, adaptability, and polycentric governance. It offers a new paradigm for sustainability in university commons by integrating bottom-up community approaches with robust institutional design, providing a theoretical foundation for implementing effective sharing schemes in rapidly evolving educational environments. Full article

Particulate matter (PM2.5) is a critical indicator of air quality and has significant health implications. This study presents the development and evaluation of a custom-built PM2.5 device, named the P-Tracker, designed to offer an accessible alternative to commercially available air quality monitors. This paper presents the design framework used to address the requirements of a low-cost, accessible device which meets the performance of existing commercial systems. Step-by step build instructions are provided for hardware and software development and connection to the P-tracker open access website which displays the data and interactive map. To demonstrate the performance, the P-Tracker was compared against leading consumer devices, including the AtmoTube Pro by AtmoTech Inc., Flow by Plume Labs, View Plus by Airthings, and the Smart Citizen Kit 2.1 by Fab Lab Barcelona, across four controlled tests. The tests included: (1) a controlled paper combustion test in which all devices were exposed to combustion aerosols in a sealed environment alongside the DustTrak 8530 (TSI Incorporated, Shoreview, MN, USA), used as the gold standard reference, where the P-Tracker achieved a Pearson correlation of 0.99 with DustTrak over the final measurement period; (2) an outdoor test comparing readings with a stationary reference sensor, Osiris (Turnkey Instruments Ltd., Rudheath, UK), where the P-Tracker recorded a mean PM2.5 concentration of 3.08 µg/m³, closely aligning with the Osiris measurement of 3.53 µg/m³ and achieving a Pearson correlation of 0.77; (3) a controlled indoor air quality assessment, where the P-Tracker displayed stable readings with a standard deviation of 0.11 µg/m³, comparable to the AtmoTube Pro; and (4) a real-world kitchen environment test, where the P-Tracker effectively captured fluctuations in PM2.5 levels due to cooking activities, maintaining a consistent response with the DustTrak reference. The results indicate varied degrees of agreement across devices in different conditions, with the P-Tracker demonstrating strong correlation and low error margins in high-pollution and controlled scenarios. This research underscores the potential of open-source, low-cost, custom-built air quality sensors which may be developed and deployed by communities to provide hyperlocal measurements of air pollution. Full article

This article presents a comparative analysis of digital manufacturing laboratories (DMLs) in Mexico and Spain. It is argued that DMLs, also known as makerspaces or FabLabs, play a key role in innovation and experimentation, but that their success depends on the relationships they establish with social actors, such as local governments, universities, and firms. Key concepts of the transformative innovation approach such as “protective space” and “embeddedness” are introduced, which allow us to understand how DMLs operate within a complex system. The comparative analysis of a DML in Mexico City (Mexico) and a DML in Valencia (Spain) allows us to identify similarities and differences in their operational contexts. While the Mexican DML faces a lack of government support and dependence on the private sector, the Spanish one benefits from strong institutional support and public policies that facilitate its development. This results in greater stability and capacity for action for the Valencian FabLab VLC compared to the Mexican FabLab Finally, we reflect on how the embeddedness received from different social actors affects the autonomy and transformative capacity of DMLs, suggesting that while both labs have the potential to innovate, their contexts and relationships determine their effectiveness and sustainability in the digital sociotechnical system. Full article

The advancement of optical materials has garnered significant interest from the global scientific community in the pursuit of efficient photocatalysts for the purification of water using light. This challenge, which cannot be addressed using traditional methods, is tackled in the present study utilizing unconventional approaches. This study presents the fabrication of an effective photocatalyst using an unconventional approach that employs explosive reactions. This method successfully produces 3D nanostructures composed of carbon nanotubes (CNTs), carbon nanofibers (CNFs), and silica–alumina nanoparticles at temperatures below 270 °C. Gold-supported silica–alumina–CNT–CNF nanostructures were synthesized and characterized using XRD, TEM, SEM, and EDX, in addition to mapping images. To study and determine the photoactivity of these produced nanostructures, two well-known photocatalysts—titanium dioxide and zinc oxide—were synthesized at the nanoscale for comparison. The results showed that the presence of CNTs and CNFs significantly reduced the band gap energy from 5.5 eV to 1.65 eV and 3.65 eV, respectively, after modifying the silica–alumina structure. In addition, complete degradation of green dye was achieved after 35 min of light exposure using the modified silica–alumina structure. Additionally, the surface properties of the modified silica–alumina had a positive role in accelerating the photocatalytic decomposition of the green dye NGB. A kinetic study confirmed that the modified silica–alumina functions as a promising additive for optical applications, accelerating the photocatalytic degradation of NGB to a rate three times faster than that of the prepared titanium dioxide and six times that of the prepared zinc oxide. Full article

This study investigated the enhanced adsorption capacity of a silver nanoparticle (AgNPs)-incorporated tamarind seed activated carbon nanocomposite (Ag/TSAC) for the elimination of methyl orange (MO) from aqueous solutions. The nanocomposite was analyzed using TGA, SEM, FTIR, and BET, revealing a mesoporous structure with a surface area of 54.92 m²/g. The results showed that the structure of tamarind seeds altered during pyrolysis, as shown by the loss of many functional groups and a weight decrease of 66.61% in the nanocomposite. The efficiency of the nanocomposite in eliminating MO was assessed by batch adsorption studies, which also examined the effects of solution pH, starting MO concentration, and nanocomposite dose. The best MO removal was seen at pH 2, indicating a positive electrostatic interaction between the dye and adsorbent. The results demonstrated that the Ag/TSAC nanocomposite significantly enhanced MO removal efficiency from 19% to 96% under optimal adsorptive conditions, due to the synergistic effect of the high surface area of activated carbon and the enhanced adsorption sites provided by the AgNPs. The study demonstrates the potential of Ag/activated carbon nanocomposite as a sustainable adsorbent for removing MO dye from wastewater using a second-order model and Langmuir model. Full article

The study aims to assess the effect of printing orientation on surface roughness and gloss of resins for 3D printing of aligners. Squared specimens (14 × 14 × 4 mm) were printed using Dental LT Clear (Formlabs, Somerville, MA, USA; LT) or Tera Harz TC-85 DAC (Graphy, Seoul, Republic of Korea; TC) with different orientations: 0° (horizontal), 90° (vertical), and as per the manufacturer’s recommendation (40° for LT, 60° for TC). A profilometer was used to measure roughness (Ra) in µm, while gloss was recorded in gloss units (GU) with a glossmeter. The collected data were statistically analyzed. Material type did not significantly influence roughness, while print orientation was an influential factor, with the orientation recommended by the manufacturer yielding the roughest specimens. Vertical printing resulted in significantly higher roughness than horizontal. Material type was a significant factor for gloss, with TC exhibiting significantly higher gloss than LT. Print direction significantly influenced gloss, with vertical printing resulting in the highest gloss. The finding of higher roughness for vertical prints can be explained by the presence of a greater number of layers. The superior gloss exhibited by TC regardless of print angulation could be related to the effective cleaning of uncured resin by centrifugation and to the high degree of monomer conversion in nitrogen atmosphere. Full article

The aim of this study was to the evaluate volumetric and linear adaptation of an indirect adhesive restoration, comparing a novel chairside 3D printer to conventional milling techniques. An intact upper premolar was selected, prepared for an overlay restoration, and replicated. A standardized overlay restoration was designed with CAD software (Cerec inLab CAD SW 4.5.2, Dentsply Sirona, Charlotte, NC, USA), maintaining equal morphology for each sample. Restorations were produced with three CAM processes: chairside 3D printer (D-FAB, DWS, Thiene, Italy), chairside milling unit (Cerec MCXL, Dentsply Sirona, Charlotte, NC, USA), and an industrial milling machine serving as control (Micro 5x, Aman Girrbach, Mäder, Austria). Once cemented, specimens were scanned using micro-computed tomography to assess volumetric, internal, and external adaptation. Data were statistically analyzed with ANOVA and post hoc Bonferroni tests. CAM technique significantly affected volumetric adaptation (p < 0.001), with the chairside 3D printer performing the best and chairside milling unit the worst. Concerning internal adaptation, the chairside milling unit performed significantly worse than the other groups (p < 0.001). No significant differences were reported for external adaptation (p > 0.05). In conclusion, CAM technique influenced volumetric and internal adaptation, with the 3D printer showing optimal volumetric adaptation and chairside milling poor internal adaptation. Full article

On 2015, after the direct study of the most important Late Villafranchian fossil collections of Europe and Western Asia, including Orce (Spain), Pirro Nord and Upper Valdarno (Italy), Appollonia (Greece), Dmanisi (Georgia) and ‘Ubeidiya (Israel), among others, our team proposed the hypothesis that suids disappeared from Europe during the time span between 1.8 and 1.2 Ma. The implications of our conclusions were significant, the arrival of Early Homo into Western Europe, dated to 1.4 Ma at the site of Barranco León in Orce (Spain), preceded the return of pigs into the continent at 1.2 Ma. This hypothesis has been recently challenged because of the finding of an incomplete metatarsal ascribed to Sus sp., with no clear stratigraphic origin, found in the XIX Century Croizet collection of Peyrolles (France), which is housed in the Natural History Museum, London, together with other weak arguments based on the absence of reliable dating for many Early Pleistocene European sites, and other hypothetical records of pigs, with no real fossil support. We answer all these questions and defend that our 2015 hypothesis is correct. Full article

Perovskite solar cells (PSCs) are the most rapidly advancing photovoltaic technology in terms of power conversion efficiency. An efficiency of 26.1% was achieved in a decade, which is on par with the efficiency of very mature silicon panels. However, PSC commercialisation is partly hindered by the difficulty of scaling these devices without efficiency loss, mostly due to the increasing sheet resistance of the transparent conductive layer substrates and the nonuniformity of the layers when deposited across large areas. Therefore, it is crucial for the commercialisation of PSCs to implement easily scalable deposition processes with low material waste and compatibility with roll-to-roll (R2R) processes to reduce manufacturing costs. Slot-die coating can meet all these requirements, allowing for great uniformity over large areas. The most recent developments in PSC upscaling using slot-die coating as the main deposition process, along with its extension to the R2R process, are reviewed, including a thorough discussion of the slot-die coating process and the theory behind its operating limits. In fact, R2R coating is a very promising strategy for PSC industrialisation, since all processing steps use low-cost materials and scalable processes at temperatures lower than 120 °C, allowing the cost-effective and high-throughput production of PSC devices. Full article

The last decade has seen dramatic progress in research on FETs with 2D channels. Starting from the single devices fabricated using exfoliated flakes in the early 2010s, by the early 2020s, 2D FETs being trialed for mass production and vertical stacking of 2D channels made by leading semiconductor companies. However, the industry is focused solely on transition metal dichalcogenide (TMD) channels coupled with conventional 3D oxide insulators such as Al₂O₃ and HfO₂. This has resulted in numerous challenges, such as poor-quality interfaces and reliability limitations due to oxide traps. At the same time, the alternative routes for 2D FETs offered by laboratory (LAB) research have not been appreciated until now, even though the use of the native oxides of 2D channels has recently resulted in the first 2D FinFETs. Considering the research progress achieved in the last decade, from this perspective, we will discuss the main challenges for industry integration of 2D FETs and also suggest possible future steps which could propel these emerging technologies towards market applications. Full article

To evaluate whether there are differences among orthodontists in the clinical management of facemask treatment for early treatment of Class III malocclusion, a survey consisting of 16 questions was conducted among members of the Italian Society of Orthodontics (SIDO). Sixty percent of the respondents were Specialists in Orthodontics (S) whereas 40% were General Dentists practicing Orthodontics (GD). Descriptive statistics were calculated to summarize the collected data. Differences in answers between S and GD were assessed with the Fisher’s exact test for dichotomous variables, chi-square test for qualitative variables, and Mann–Whitney test for ordinal variables. A total of 151 clinicians participated in this survey. As for treatment timing, about 80% of the participants reported treating Class III patients with RPE and facemask between 5 and 8 years of age. Most of the participants requested the patients to wear the facemask in the afternoon and at night for a period of 9 or 12 months with recommended forces of 500 g per side. Comparisons between S and GD showed that S preferred the Petit facemask whereas GD favored the Delaire’s type facemask (Fisher’s Exact test, p = 0.0005). S and GD also differed significantly in their judgment of the most critical time of treatment, which for the majority of GD was the initial period but for the S was the final period (Chi-square test p = 0.0188). This survey showed that the facemask is not well received by the patients who, along with their parents, express concerns regarding its tolerability. Full article

Directed evolution is a pivotal strategy for new antibody discovery, which allowed the generation of high-affinity Fabs against gliadin from two antibody libraries in our previous studies. One of the libraries was exclusively derived from celiac patients’ mRNA (immune library) while the other was obtained through a protein engineering approach (semi-immune library). Recent advances in high-throughput DNA sequencing techniques are revolutionizing research across genomics, epigenomics, and transcriptomics. In the present work, an Oxford Nanopore in-lab sequencing device was used to comprehensively characterize the composition of the constructed libraries, both at the beginning and throughout the phage-mediated selection processes against gliadin. A customized analysis pipeline was used to select high-quality reads, annotate chain distribution, perform sequence analysis, and conduct statistical comparisons between the different selection rounds. Some immunological attributes of the most representative phage variants after the selection process were also determined. Sequencing results revealed the successful transfer of the celiac immune response features to the immune library and the antibodies derived from it, suggesting the crucial role of these features in guiding the selection of high-affinity recombinant Fabs against gliadin. In summary, high-throughput DNA sequencing has improved our understanding of the selection processes aimed at generating molecular binders against gliadin. Full article