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21 pages, 22377 KB  
Article
Ecological Risk Assessment of Innovative Soil Substitute Cover in Post-Mining Land Reclamation: A Case Study of the Janina Mine Spoil Heap
by Angelika Więckol-Ryk and Magdalena Cempa
Sustainability 2026, 18(14), 7072; https://doi.org/10.3390/su18147072 - 10 Jul 2026
Viewed by 365
Abstract
Artificial soils derived from coal combustion by-products and industrial waste have been successfully used for mine spoil reclamation; however, their ecological risk and toxic element migration in the soil–plant system have not been assessed. The objective of this study was to evaluate the [...] Read more.
Artificial soils derived from coal combustion by-products and industrial waste have been successfully used for mine spoil reclamation; however, their ecological risk and toxic element migration in the soil–plant system have not been assessed. The objective of this study was to evaluate the ecological risks in soil substitute covers after five years of their exposition, using the ecological risk factor (ERi), potential ecological risk index (PERI) and geoaccumulation index. The modified BCR-sequential extraction method was applied to determine the chemical partitioning of the most toxic heavy metals (Cd, Cr, Cu, Ni, Pb, Zn). Additionally, the bioconcentration and translocation factors were used to assess the uptake of toxic elements by Phragmites australis. Findings from PERI indicate a moderate risk (239 and 258), mainly associated with moderate and considerable ERi for Cd and Hg, respectively. The other toxic metals are associated with a low risk (ERi < 40). Sequential extraction results showed the lowest concentrations of heavy metals in F1 fraction (0–30%) and increased in subsequent fractions: F2 (1–43%), F3 (10–62%) and F4 (10–89%). The calculated BCF values were below 1, indicating that the concentration of toxic metals in plants was lower than that in the soil substitute. The only exception was observed for Mn and Sn (BCF > 1). The results suggest that the tested soil substitutes are suitable for the reclamation of post-mining areas and may support sustainable biomass production. However, due to industrial atmospheric deposition and ecological risk associated with selected trace elements, continued monitoring of toxic metals is recommended. Full article
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22 pages, 3971 KB  
Article
Estimating the Vulnerability to Hydrometeorological Phenomena in Mexican Coffee Crops
by Ofelia Andrea Valdés-Rodríguez and Fernando Salas-Martínez
Crops 2026, 6(3), 50; https://doi.org/10.3390/crops6030050 - 5 May 2026
Viewed by 838
Abstract
Coffee plantations are highly vulnerable to climatic factors. In this regard, the vulnerability of coffee agroecosystems to extreme hydrometeorological events has been underexplored. This research proposes a method to assess coffee plantations’ vulnerability to five phenomena that have led to disaster declarations in [...] Read more.
Coffee plantations are highly vulnerable to climatic factors. In this regard, the vulnerability of coffee agroecosystems to extreme hydrometeorological events has been underexplored. This research proposes a method to assess coffee plantations’ vulnerability to five phenomena that have led to disaster declarations in the municipalities where they are cultivated: extreme rainfall, tropical cyclones, floods, snow and low temperatures, and drought. This study considered coffee production, local climate information, hydrometeorological records, and environmental protection actions, spanning 22 years in the eastern state of Veracruz, Mexico. All data were normalized and evaluated for three production values: harvested area ratio, yield, and volume. The Exposition accounted for the number of events, correlating production data with phenomena to assess sensitivity, while the adaptive capacity was assessed by considering environmental protection actions. The results indicated that the most frequent phenomena were extreme rainfall, followed by tropical cyclones, snow and low temperatures, droughts, and floods. However, tropical cyclones accounted for the highest number of vulnerabilities, and drought caused the highest level of vulnerabilities. Snow and cold temperatures reduced vulnerabilities, and floods have non-statistical effects. In general, coffee agroecosystems have a low vulnerability index (6.21 on a scale of 15) due to their location within the local forest. Full article
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19 pages, 679 KB  
Systematic Review
Educational Innovation and University Research, Distinction, Points of Contact and Productive Interactions
by Raquel Ayala-Carabajo and Joe Llerena-Izquierdo
Educ. Sci. 2026, 16(4), 510; https://doi.org/10.3390/educsci16040510 - 25 Mar 2026
Viewed by 1128
Abstract
Higher education is undergoing a constant paradigm shift, transforming itself into a system of innovation for society. This study has explored and determined the relationship between educational innovation and research in university contexts in order to distinguish, compare, and establish dynamics of interaction. [...] Read more.
Higher education is undergoing a constant paradigm shift, transforming itself into a system of innovation for society. This study has explored and determined the relationship between educational innovation and research in university contexts in order to distinguish, compare, and establish dynamics of interaction. The contributions of scientific articles published in WoS-indexed journals between 2019 and 2025 in a total of 108 sources were analyzed using the PRISMA method and an analysis inspired by grounded theory with open coding and axial coding (mixed method). As a result, both functions have been conceptually differentiated while establishing these points of contact, productive interactions, and their relationship with university institutional management. It is concluded that higher education is facing a paradigm shift, transforming itself from a center of knowledge and professional training to the hub of innovation systems. The main contribution of this study is its exposition of how this profound change is taking place and the conditions of research–innovation interaction in the university setting. Full article
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28 pages, 4882 KB  
Article
Seasonal Changes of Extreme Precipitation in Relation to Circulation Conditions in the Sudetes Mountains
by Irena Otop and Bartłomiej Miszuk
Water 2026, 18(1), 103; https://doi.org/10.3390/w18010103 - 1 Jan 2026
Cited by 1 | Viewed by 1490
Abstract
Heavy precipitation, and its dependence on atmospheric circulation, is one of the most important weather features in Central Europe. The Polish–Czech Sudetes Mountains and their northern foreland are one of the regions where such precipitation, under certain circulation conditions, often results in floods. [...] Read more.
Heavy precipitation, and its dependence on atmospheric circulation, is one of the most important weather features in Central Europe. The Polish–Czech Sudetes Mountains and their northern foreland are one of the regions where such precipitation, under certain circulation conditions, often results in floods. The main goal of this paper is to examine multiannual changes in seasonal heavy precipitation between 1961–2020 and to assess their relationship with atmospheric circulation. The data were derived from the Polish and Czech meteorological stations, representing various altitudes and geographical regions. For the purposes of the study, several indices were used, including 1-, 3-, and 5-day maximum precipitation, as well as two indices based on the 90th and 95th percentile thresholds. In the analysis concerning atmospheric circulation, the Lityński classification was considered. The results show that the changes in heavy precipitation usually do not indicate homogeneous directions and are strongly affected by applied indices, seasons, and various geographic factors. Those include the northern/southern slope exposition, which significantly determines heavy precipitation under circulation conditions typical for individual seasons. This particularly concerns heavy precipitation for the north and northeast types, which contribute to higher rates of the considered index, especially in the northern part of the mountains. Full article
(This article belongs to the Special Issue Analysis of Extreme Precipitation Under Climate Change)
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24 pages, 22609 KB  
Article
Terrain-Based High-Resolution Microclimate Modeling for Cold-Air-Pool-Induced Frost Risk Assessment in Karst Depressions
by András Dobos, Réka Farkas and Endre Dobos
Climate 2025, 13(10), 205; https://doi.org/10.3390/cli13100205 - 30 Sep 2025
Cited by 4 | Viewed by 3032
Abstract
Cold-air pooling (CAP) and frost risk represent significant climate-related hazards in karstic and agricultural environments, where local topography and surface cover strongly modulate microclimatic conditions. This study focuses on the Mohos sinkhole, Hungary’s cold pole, situated on the Bükk Plateau, to investigate the [...] Read more.
Cold-air pooling (CAP) and frost risk represent significant climate-related hazards in karstic and agricultural environments, where local topography and surface cover strongly modulate microclimatic conditions. This study focuses on the Mohos sinkhole, Hungary’s cold pole, situated on the Bükk Plateau, to investigate the formation, structure, and persistence of CAPs in a Central European karst depression. High-resolution terrain-based modeling was conducted using UAV-derived digital surface models combined with multiple GIS tools (Sky-View Factor, Wind Exposition Index, Cold Air Flow, and Diurnal Anisotropic Heat). These models were validated and enriched by multi-level temperature measurements and thermal imaging under various synoptic conditions. Results reveal that temperature inversions frequently form during clear, calm nights, leading to extreme near-surface cold accumulation within the sinkhole. Inversions may persist into the day due to topographic shading and density stratification. Vegetation and basin geometry influence radiative and turbulent fluxes, shaping the spatial extent and intensity of cold-air layers. The CAP is interpreted as part of a broader interconnected multi-sinkhole system. This integrated approach offers a transferable, cost-effective framework for terrain-driven frost hazard assessment, with direct relevance to precision agriculture, mesoscale model refinement, and site-specific climate adaptation in mountainous or frost-sensitive regions. Full article
(This article belongs to the Section Climate and Environment)
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28 pages, 3926 KB  
Article
Could the Presence of Ferrihydrite in a Riverbed Impacted by Mining Leachates Be Linked to a Reduction in Contamination and Health Indexes?
by Asunción Guadalupe Morales-Mendoza, Ana Karen Ivanna Flores-Trujillo, Luz María Del-Razo, Betsy Anaid Peña-Ocaña, Fanis Missirlis and Refugio Rodríguez-Vázquez
Water 2025, 17(15), 2167; https://doi.org/10.3390/w17152167 - 22 Jul 2025
Cited by 1 | Viewed by 1503
Abstract
Taxco de Alarcón (Mexico) has been affected by mining activities and the presence of potentially toxic elements (PTEs). In this study, water samples from the Acamixtla, Taxco, and San Juan rivers were analyzed using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) to determine [...] Read more.
Taxco de Alarcón (Mexico) has been affected by mining activities and the presence of potentially toxic elements (PTEs). In this study, water samples from the Acamixtla, Taxco, and San Juan rivers were analyzed using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) to determine PTE concentrations. Statistical analyses included principal component analysis, Pearson’s correlation, the Pollution Index, and a Health Risk Assessment. Additionally, solid samples from the San Juan River with leachate from the “La Guadalupana” Mine (RSJMG S2.3) were characterized using Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). Identified PTEs included As, Cr, Ni, Zn, Fe, Mn, Cu, Cd, Pb, Se, and Li. Principal component analysis explained 94.8% of the data variance, and Pearson’s correlation revealed significant associations (p < 0.05) among Fe, As, Cu, Cd, Pb, and Zn. The RSJMG S2.3 site exhibited the highest Pollution Index value (8491.56) and the highest health exposure risks. Lower contamination levels at other sites may be attributed to the complexation of PTEs with ferrihydrite, which was identified in the RSJMG S2.3 site through microscopy and infrared analyses. These findings suggest that the in situ formation of ferrihydrite may enhance the adsorption of PTEs, thereby mitigating environmental contamination and potential health risks. Full article
(This article belongs to the Section Water Quality and Contamination)
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40 pages, 17802 KB  
Article
Mapping Windthrow Risk in Pinus radiata Plantations Using Multi-Temporal LiDAR and Machine Learning: A Case Study of Cyclone Gabrielle, New Zealand
by Michael S. Watt, Andrew Holdaway, Nicolò Camarretta, Tommaso Locatelli, Sadeepa Jayathunga, Pete Watt, Kevin Tao and Juan C. Suárez
Remote Sens. 2025, 17(10), 1777; https://doi.org/10.3390/rs17101777 - 20 May 2025
Cited by 5 | Viewed by 3144
Abstract
As the frequency of strong storms and cyclones increases, understanding wind risk in both existing and newly established plantation forests is becoming increasingly important. Recent advances in the quality and availability of remotely sensed data have significantly improved our capability to make large-scale [...] Read more.
As the frequency of strong storms and cyclones increases, understanding wind risk in both existing and newly established plantation forests is becoming increasingly important. Recent advances in the quality and availability of remotely sensed data have significantly improved our capability to make large-scale wind risk predictions. This study models the loss of radiata pine (Pinus radiata D.Don) plantations following a severe cyclone within the Gisborne Region of New Zealand through leveraging repeat regional LiDAR acquisitions, optical imagery, and various surfaces describing key climatic, topographic, and storm-specific conditions. A random forest model was trained on 9713 plots classified as windthrow or no-windthrow. Model validation using 50 iterations of 80/20 train/test splits achieved robust accuracy (accuracy = 0.835; F1 score = 0.841; AUC = 0.913). In comparison to most European empirical models (AUC = 0.51–0.90), our framework demonstrated superior discrimination, underscoring its value for regions prone to cyclones. Among the 14 predictor variables, the most influential were mean windspeed during February, the wind exposition index, site drainage, and stand age. Model predictions closely aligned with the estimated 3705 hectares of cyclone-induced forest damage and indicated that 20.9% of unplanted areas in the region would be at risk of windthrow at age 30 if established in radiata pine. The resulting wind risk surface serves as a valuable decision-support tool for forest managers, helping to mitigate wind risk in existing forests and guide adaptive afforestation strategies. Although developed for radiata pine plantations in New Zealand, the approach and findings have broader relevance for forest management in cyclone-prone regions worldwide, particularly where plantation forestry is widely practised. Full article
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18 pages, 4679 KB  
Article
Coal Combustion Warning System Based on TDLAS and Performance Research
by Zhitao Xie, Guanyu Lin, Jianing Wang, Xi Wang, Weijia Li, Pengbo Li and Hengyuan Kong
Photonics 2025, 12(5), 493; https://doi.org/10.3390/photonics12050493 - 15 May 2025
Cited by 1 | Viewed by 1324
Abstract
As the signature gas released before coal combustion, methane’s telemetry accuracy is susceptible to environmental influences, which is a difficult problem that needs to be solved. This article provides a detailed exposition on the application of Tunable Diode Laser Absorption Spectroscopy (TDLAS) technology [...] Read more.
As the signature gas released before coal combustion, methane’s telemetry accuracy is susceptible to environmental influences, which is a difficult problem that needs to be solved. This article provides a detailed exposition on the application of Tunable Diode Laser Absorption Spectroscopy (TDLAS) technology in the field of gas monitoring, with particular emphasis on its advantages in coal safety detection. The coal combustion experiment is conducted to determine the required performance indexes. Through the temperature compensation algorithm and normalized signals, the impact of factors such as ambient temperature and environmental noise is reduced, effectively improving the signal-to-noise ratio and accuracy. The experiments demonstrate that this system effectively lowers the detection limit for methane while improving measurement accuracy, thereby providing robust support for the early warning of coal spontaneous combustion. Full article
(This article belongs to the Special Issue Advances in Laser Spectroscopy: From Fundamentals to Applications)
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28 pages, 5794 KB  
Article
Rehabilitated Tailing Piles in the Metropolitan Ruhr Area (Germany) Identified as Green Cooling Islands and Explained by K-Mean Cluster and Random Forest Regression Analyses
by Britta Stumpe and Bernd Marschner
Remote Sens. 2024, 16(23), 4348; https://doi.org/10.3390/rs16234348 - 21 Nov 2024
Cited by 4 | Viewed by 2534
Abstract
Urban green spaces, such as parks, cemeteries, and allotment gardens provide important cooling functions for mitigating the urban heat island (UHI) effect. In the densely populated Ruhr Area (Germany), rehabilitated tailing piles (TPs), as relicts of the coal-mining history, are widespread hill-shaped landscape [...] Read more.
Urban green spaces, such as parks, cemeteries, and allotment gardens provide important cooling functions for mitigating the urban heat island (UHI) effect. In the densely populated Ruhr Area (Germany), rehabilitated tailing piles (TPs), as relicts of the coal-mining history, are widespread hill-shaped landscape forms mainly used for local recreation. Their potential role as cooling islands has never been analyzed systematically. Therefore, this study aimed at investigating the TP surface cooling potential compared to other urban green spaces (UGSs). We analyzed the factors controlling the piles’ summer land surface temperature (LST) patterns using k-mean clustering and random forest regression modeling. Generally, mean LST values of the TPs were comparable to those of other UGSs in the region. Indices describing vegetation moisture (NDMI), vitality (NDVI), and height (VH) were found to control the LST pattern of the piles during summer. The index for soil moisture (TVDI) was directly related to VH, with the highest values on the north and northeast-facing slopes and lowest on slopes with south and southeast expositions. Terrain attributes such as altitude, slope, aspect, and curvature were of minor relevance in that context, except on TPs exceeding heights of 125 m. In conclusion, we advise urban planners to maintain and improve the benefit of tailing piles as green cooling islands for UHI mitigation. As one measure, the soil’s water-holding capacity could be increased through thicker soil covers or soil additives during mine tailing rehabilitation, especially on the piles’ south and southeast expositions. Full article
(This article belongs to the Section Urban Remote Sensing)
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8 pages, 252 KB  
Article
Reducing the Number of Times Eating Out Helps to Decrease Adiposity (Overweight/Obesity) in Children
by Arturo Parra-Solano, Minerva Hernández-Flores, Bernarda Sánchez, Carolina Paredes, Luis Monroy, Florinda Palacios, Laura Almaguer and Ana Rodriguez-Ventura
Nutrients 2024, 16(17), 2899; https://doi.org/10.3390/nu16172899 - 30 Aug 2024
Cited by 2 | Viewed by 3811
Abstract
Adiposity is a chronic disease that must be treated from childhood. Despite the transcendence of improving habits, few interventions report their contribution to decreasing adiposity. Methods: This cohort enrolled children and teens of any gender, 8–18 years old, and with a body mass [...] Read more.
Adiposity is a chronic disease that must be treated from childhood. Despite the transcendence of improving habits, few interventions report their contribution to decreasing adiposity. Methods: This cohort enrolled children and teens of any gender, 8–18 years old, and with a body mass index (BMI) z-score of ≥1 into “Sacbe”, a comprehensive program to identify which eating habits could reduce BMI z-score. The sample size calculated was 110 participants. We recorded anthropometric measures, clinical history, and habits. A clinically relevant reduction in BMI z-score was defined as ≥0.5 over 12 months or its equivalent according to the months of follow-up. Results: 58.2% were female, the median age was 12 years (range: 9.1–14.7), and the mean BMI z-score was 2.30 ± 0.83. The 82.7% achieved a reduced BMI z-score but 41.8% achieved a clinically relevant reduction with a median follow-up of 6.7 months. Eating out less than once per week was associated with this outcome, even after adjusting for energy intake, other eating patterns, sedentary screen time, physical activity, sleep duration, and sitting time (HR 2.12; 95% CI: 1.07–4.21). Conclusions: Eating out < once/week implicates less processed food exposition and better quality of food; this habit could be the most effective to reduce childhood adiposity. Full article
(This article belongs to the Special Issue Diet and Lifestyle Intervention for Weight Management)
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16 pages, 7092 KB  
Article
The Antagonistic and Synergistic Role of Fe3+ Compounds in Chemo- and Electrochemotherapy in Human Colon Cancer In Vitro
by Wojciech Szlasa, Wiktoria Mazurek, Anna Szewczyk, Nina Rembiałkowska, Joanna Tunikowska and Julita Kulbacka
Pharmaceuticals 2024, 17(5), 651; https://doi.org/10.3390/ph17050651 - 17 May 2024
Cited by 1 | Viewed by 2463
Abstract
Colon cancer (CC) management includes surgery, radio- and chemotherapy based on treatment with 5-fluorouracil (5-FU) or its derivatives. However, its application is limited to low-grade carcinomas. Thus, much research has been conducted to introduce new techniques and drugs to the therapy. CC mostly [...] Read more.
Colon cancer (CC) management includes surgery, radio- and chemotherapy based on treatment with 5-fluorouracil (5-FU) or its derivatives. However, its application is limited to low-grade carcinomas. Thus, much research has been conducted to introduce new techniques and drugs to the therapy. CC mostly affects older people suffering from cardiac diseases, where iron compounds are commonly used. Ferric citrate and iron (III)–EDTA complexes have proven to be effective in colon cancer in vitro. This study aimed to determine the potency and action of iron-containing compounds in colon cancer treatment by chemo- and electrochemotherapy in both nano- and microsecond protocols. The viability of the cells was assessed after standalone iron (III) citrate and iron (III)–EDTA incubation. Both compounds were also assessed with 5-FU to determine the combination index. Additionally, frataxin expression was taken as the quantitative response to the exposition of iron compounds. Each of the substances exhibited a cytotoxic effect on the LoVo cell line. Electroporation with standalone drugs revealed the potency of 5-FU and iron(III)–EDTA in CC treatment. The combination of 5-FU with iron(III)–EDTA acted synergistically, increasing the viability of the cells in the nanosecond electrochemotherapy protocol. Iron(III)–EDTA decreased the frataxin expression, thus inducing ferroptosis. Iron(III) citrate induced the progression of cancer; therefore, it should not be considered as a potential therapeutic option. The relatively low stability of iron(III) citrate leads to the delivery of citrate anions to cancer cells, which could increase the Krebs cycle rate and promote progression. Full article
(This article belongs to the Section Medicinal Chemistry)
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20 pages, 16922 KB  
Article
An Index-Based Method to Assess the Resilience of Urban Areas to Coastal Flooding: The Case of Attica, Greece
by Charalampos Nikolaos Roukounis, Vasiliki K. Tsoukala and Vassilios A. Tsihrintzis
J. Mar. Sci. Eng. 2023, 11(9), 1776; https://doi.org/10.3390/jmse11091776 - 11 Sep 2023
Cited by 9 | Viewed by 5095
Abstract
The aim of this study is to assess the resilience of coastal urban areas and their exposure to sea-level rise and coastal flooding, using the proposed Coastal Resilience Index (CResI). The CResI is an innovative combination of diverse characteristics. It includes 19 parameters [...] Read more.
The aim of this study is to assess the resilience of coastal urban areas and their exposure to sea-level rise and coastal flooding, using the proposed Coastal Resilience Index (CResI). The CResI is an innovative combination of diverse characteristics. It includes 19 parameters and is implemented using GIS techniques. The parameters included in the CResI are classified into six category factors (geomorphology, flooding, wave exposition, land use, socioeconomic, and infrastructure/functional). The Analytic Hierarchy Process is used to assign weights and rank the parameters. The framework is tested in the southwest waterfront of the Athens Metropolitan Area in Greece. The study identified that around 25% of the coastal area could be at risk of coastal flooding in the upcoming years, including areas in both the metropolitan and suburban environments. As a result, the need for adaptation measures cannot be overlooked. Full article
(This article belongs to the Special Issue Estuaries, Coasts, and Seas in a Changing Climate)
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12 pages, 2083 KB  
Article
Near-Infrared Spectroscopy-Guided, Individualized Arterial Blood Pressure Management for Carotid Endarterectomy under General Anesthesia: A Randomized, Controlled Trial
by Tina Tomić Mahečić, Branko Malojčić, Dinko Tonković, Mirabel Mažar, Robert Baronica, Snježana Juren Meaški, Andrea Crkvenac Gregorek, Jens Meier and Martin W. Dünser
J. Clin. Med. 2023, 12(15), 4885; https://doi.org/10.3390/jcm12154885 - 25 Jul 2023
Cited by 7 | Viewed by 3213
Abstract
Background: Differences in blood pressure can influence the risk of brain ischemia, perioperative complications, and postoperative neurocognitive function in patients undergoing carotid endarterectomy (CEA). Methods: In this single-center trial, patients scheduled for CEA under general anesthesia were randomized into an intervention [...] Read more.
Background: Differences in blood pressure can influence the risk of brain ischemia, perioperative complications, and postoperative neurocognitive function in patients undergoing carotid endarterectomy (CEA). Methods: In this single-center trial, patients scheduled for CEA under general anesthesia were randomized into an intervention group receiving near-infrared spectroscopy (NIRS)-guided blood pressure management during carotid cross-clamping and a control group receiving standard care. The primary endpoint was postoperative neurocognitive function assessed before surgery, on postoperative days 1 and 7, and eight weeks after surgery. Perioperative complications and cerebral autoregulatory capacity were secondary endpoints. Results: Systolic blood pressure (p < 0.001) and norepinephrine doses (89 (54–122) vs. 147 (116–242) µg; p < 0.001) during carotid cross-clamping were lower in the intervention group. No group differences in postoperative neurocognitive function were observed. The rate of perioperative complications was lower in the intervention group than in the control group (3.3 vs. 26.7%, p = 0.03). The breath-holding index did not differ between groups. Conclusions: Postoperative neurocognitive function was comparable between CEA patients undergoing general anesthesia in whom arterial blood pressure during carotid cross-clamping was guided using NIRS and subjects receiving standard care. NIRS-guided, individualized arterial blood pressure management resulted in less vasopressor exposition and a lower rate of perioperative complications. Full article
(This article belongs to the Special Issue Carotid Angioplasty and Stenting: Current State and Future Directions)
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20 pages, 10730 KB  
Article
On the Role of Microstructure and Defects in the Room and High-Temperature Tensile Behavior of the PBF-LB A357 (AlSi7Mg) Alloy in As-Built and Peak-Aged Conditions
by Lavinia Tonelli, Erica Liverani, Gianluca Di Egidio, Alessandro Fortunato, Alessandro Morri and Lorella Ceschini
Materials 2023, 16(7), 2721; https://doi.org/10.3390/ma16072721 - 29 Mar 2023
Cited by 11 | Viewed by 3067
Abstract
Additive processes like Laser Beam Powder Bed Fusion (PBF-LB) result in a distinctive microstructure characterized by metastability, supersaturation, and finesse. Post-process heat treatments modify microstructural features and tune mechanical behavior. However, the exposition at high temperatures can induce changes in the microstructure. Therefore, [...] Read more.
Additive processes like Laser Beam Powder Bed Fusion (PBF-LB) result in a distinctive microstructure characterized by metastability, supersaturation, and finesse. Post-process heat treatments modify microstructural features and tune mechanical behavior. However, the exposition at high temperatures can induce changes in the microstructure. Therefore, the present work focuses on the analyses of the tensile response at room and high (200 °C) temperature of the A357 (AlSi7Mg0.6) alloy processed by PBF-LB and subjected to tailored T5 (direct aging) and T6R (rapid solution treatment, quenching, and aging) treatments. Along with the effect of microstructural features in the as-built T5 and T6R alloy, the role of typical process-related defects is also considered. In this view, the structural integrity of the alloy is evaluated by a deep analysis of the work-hardening behavior, and quality indexes have been compared. Results show that T5 increases tensile strength at room temperature without compromising ductility. T6R homogenizes the microstructure and enhances the structural integrity by reducing the detrimental effect of defects, resulting in the best trade-off between strength and ductility. At 200 °C, tensile properties are comparable, but if resilience and toughness moduli are considered, as-built and T5 alloys show the best overall mechanical performance. Full article
(This article belongs to the Special Issue Heat Treatments and Performance of Alloy and Metal)
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17 pages, 1971 KB  
Article
Synergistic Antioxidant Effect of Prebiotic Ginseng Berries Extract and Probiotic Strains on Healthy and Tumoral Colorectal Cell Lines
by Alessandra De Giani, Monica Oldani, Matilde Forcella, Marina Lasagni, Paola Fusi and Patrizia Di Gennaro
Int. J. Mol. Sci. 2023, 24(1), 373; https://doi.org/10.3390/ijms24010373 - 26 Dec 2022
Cited by 10 | Viewed by 4566
Abstract
Oxidative stress caused by reactive oxygen species (ROS, O2, HO•, and H2O2) affects the aging process and the development of several diseases. A new frontier on its prevention includes functional foods with both specific probiotics [...] Read more.
Oxidative stress caused by reactive oxygen species (ROS, O2, HO•, and H2O2) affects the aging process and the development of several diseases. A new frontier on its prevention includes functional foods with both specific probiotics and natural extracts as antioxidants. In this work, Panax ginseng C.A. Meyer berries extract was characterized for the presence of beneficial molecules (54.3% pectin-based polysaccharides and 12% ginsenosides), able to specifically support probiotics growth (OD600nm > 5) with a prebiotic index of 0.49. The administration of the extract to a probiotic consortium induced the production of short-chain fatty acids (lactic, butyric, and propionic acids) and other secondary metabolites derived from the biotransformation of Ginseng components. Healthy and tumoral colorectal cell lines (CCD841 and HT-29) were then challenged with these metabolites at concentrations of 0.1, 0.5, and 1 mg/mL. The cell viability of HT-29 decreased in a dose-dependent manner after the exposition to the metabolites, while CCD841 vitality was not affected. Regarding ROS production, the metabolites protected CCD841 cells, while ROS levels were increased in HT-29 cells, potentially correlating with the less functionality of glutathione S-transferase, catalase, and total superoxide dismutase enzymes, and a significant increase in oxidized glutathione. Full article
(This article belongs to the Section Molecular Pharmacology)
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